Adc Therapeutics Sa Stock Price, News & Analysis

ADC Therapeutics (NYSE: ADCT) has entered a joint venture with Overland Pharmaceuticals, forming Overland ADCT BioPharma (CY) Limited. Under this agreement, ADC has licensed exclusive rights for the development and commercialization of four drugs, including Lonca, in Greater China and Singapore. Overland Pharmaceuticals will invest $50 million, acquiring a 51% stake, while ADC retains 49%. This strategic partnership aims to expand access to innovative therapies in oncology and could result in additional milestone payments and royalties for ADC.

ADC Therapeutics (NYSE:ADCT) and Overland Pharmaceuticals have established Overland ADCT BioPharma (CY) Limited to develop four ADC product candidates for hematologic and solid tumors in Greater China and Singapore. Overland Pharmaceuticals has invested $50 million, granting them a 51% stake. ADC Therapeutics retains 49% and can earn milestone payments and royalties. The lead product, Loncastuximab tesirine (Lonca), has shown a 48.3% overall response rate in pivotal trials for relapsed DLBCL. The partnership aims to expand access to innovative therapies in the licensed territories.

ADC Therapeutics (NYSE:ADCT) released updated clinical data for its lead programs, loncastuximab tesirine (Lonca) and camidanlumab tesirine (Cami), at the ASH Annual Meeting. Lonca's pivotal LOTIS 2 trial indicated a 48.3% overall response rate and a 24.8% complete response rate in patients with relapsed or refractory DLBCL. The FDA accepted Lonca's Biologics License Application for priority review, with a PDUFA date of May 21, 2021. Cami's Phase 2 trial showed an 83% overall response rate in Hodgkin lymphoma patients. Both drugs exhibit manageable safety profiles.

ADC Therapeutics SA (NYSE:ADCT) announced a live conference call on December 7, 2020, at 8:00 a.m. ET to showcase presentations at the 62nd ASH Annual Meeting. Key presentations will focus on the lead candidate, loncastuximab tesirine (Lonca), for treating relapsed diffuse large B-cell lymphoma and camidanlumab tesirine (Cami) for Hodgkin lymphoma. Lonca has a 48.3% overall response rate in a Phase 2 trial, while Cami showed an 86.5% response in Phase 1. The call will include insights from expert Mehdi Hamadani, MD, and will be available via webcast.

ADC Therapeutics SA (NYSE: ADCT) announced the FDA's acceptance of its Biologics License Application (BLA) for loncastuximab tesirine (Lonca), targeting relapsed or refractory diffuse large B-cell lymphoma (DLBCL), with a priority review status. A PDUFA target date is set for May 21, 2021. The BLA is based on the LOTIS 2 trial, reporting a 48.3% overall response rate among 145 patients. Common severe adverse events included neutropenia (25.5%) and thrombocytopenia (17.9%). Long-term efficacy and safety data are pending further studies.

ADC Therapeutics (ADCT) reported its third quarter 2020 financial results and business highlights. Key points include the submission of a Biologics License Application for its drug Lonca to the FDA for treating relapsed DLBCL, with a commercial launch planned for mid-2021. The company initiated Phase 3 and Phase 2 clinical trials for Lonca, showing promising preliminary data from ongoing trials. Cash and cash equivalents reached $494.4 million. However, the adjusted net loss widened to $41.3 million from $31.1 million year-over-year, mainly due to increased operational costs.

ADC Therapeutics SA (NYSE: ADCT) announced that CEO Chris Martin will present a company overview at the Stifel 2020 Virtual Healthcare Conference on November 17, 2020, at 9:20 am ET. A live webcast will be accessible, and an archived version will be available post-event. The company specializes in developing antibody drug conjugates (ADCs) for hematological malignancies and solid tumors, with lead products Loncastuximab tesirine and Camidanlumab tesirine showing promising results in pivotal trials. For more details, visit adctherapeutics.com.

ADC Therapeutics (NYSE: ADCT) announces a conference call on November 12, 2020, at 8:30 AM ET to discuss its financial results for Q3 2020 and provide business updates. The call can be accessed via phone or live webcast. The company focuses on developing targeted antibody drug conjugates (ADCs) for treating hematological malignancies and solid tumors. Key product candidates include Loncastuximab tesirine, which demonstrated a 48.3% overall response rate in a pivotal clinical trial, and Camidanlumab tesirine, with an 86.5% response rate in Hodgkin lymphoma patients.

ADC Therapeutics SA (NYSE:ADCT) announced eight abstracts for presentation at the 62nd ASH Annual Meeting, focusing on the efficacy of its ADCs, particularly loncastuximab tesirine (Lonca) and camidanlumab tesirine (Cami). The data includes results from pivotal trials, showcasing a 48.3% overall response rate for Lonca in relapsed/refractory diffuse large B-cell lymphoma. The abstracts will be published in the November supplemental issue of Blood. ADC Therapeutics is positioned as a leader in developing targeted therapies for hematological malignancies.