Firefly Neuroscience, Inc. develops AI-enabled precision neuroscience tools built around EEG/ERP brain data, including its FDA 510(k)-cleared brain analytics technology, the BNA platform, the Evoke System and the CLEAR Platform. News about AIFF centers on commercialization of cognitive electrophysiology analytics, growth in brain scan volumes, expansion of its standardized EEG/ERP data repository, and the use of NVIDIA GPU acceleration for signal processing and biomarker discovery.
Recurring company updates also cover research applications in neurological and mental health conditions such as ADHD, depression, dementia, anxiety disorders, concussions and cognitive disorders; partnerships with clinics, researchers and institutional customers; integration of Evoke Neuroscience; and periodic financial results tied to equipment sales, rentals, per-use fees and services for projects or clinical studies.
Firefly (NASDAQ: AIFF) reported a >20-fold expansion of its commercial footprint and a 33-fold increase in EEG/ERP scan volumes, ending 2025 with 99 commercial users and more than 10,800 EEG/ERP brain scans.
The company cited its acquisition of Evoke Neuroscience and deployment of NVIDIA L40S GPU acceleration as enablers for AI-driven biomarker discovery and progress toward an EEG/ERP-based foundation model of the human brain.
Firefly Neuroscience (NASDAQ: AIFF) reported Q3 2025 results showing significant integration benefits from its May 2025 acquisition of Evoke. Q3 revenue was $388,000, up from $33,000 year‑over‑year and +30% sequentially. EEG/ERP scan volumes rose 10.9% sequentially. Total operating expenses fell ~35% versus Q3 2024 to ~$2.8 million, helping reduce Q3 net loss to ~$2.6 million (‑38% year‑over‑year). Cash used in operations was ~$1.5 million (lowest quarter in first nine months of 2025) and the company ended the quarter with $4.3 million cash. The company also highlighted new CLEAR preprocessing technology and strategic partnerships advancing its EEG/ERP offerings.
Firefly Neuroscience (NASDAQ: AIFF) has announced a strategic partnership with HealingMaps and Advanced Behavioral Strategies to provide EEG-based cognitive analytics to over 2,500 specialized clinics across North America. The collaboration follows HealingMaps' launch of the Healing Health Alliance, a pioneering Group Purchasing Organization for alternative therapy clinics.
The partnership will integrate Firefly's FDA-510(k)-cleared brain health analytics platform, which uses AI and EEG technology to provide objective assessments, replacing traditional subjective questionnaires. The platform analyzes brain activity using the world's largest normative EEG/ERP database, offering standardized insights for ketamine, psilocybin, and TMS treatments.
Firefly Neuroscience (NASDAQ: AIFF) has announced the successful deployment of its new 'CLEAR' (CLeaning EEG ARtifacts) Platform, powered by NVIDIA L40S GPU technology. The platform represents a significant advancement in EEG data preprocessing, achieving 60-80% faster processing times while maintaining high signal quality.
The CLEAR Platform utilizes state-of-the-art signal processing and machine learning techniques to clean EEG recordings from various artifacts, including muscle activity and environmental interference. This technology enhancement enables better detection of neural biomarkers crucial for neurological and psychiatric condition diagnosis and treatment.
This development follows Firefly's recent acceptance into the NVIDIA Connect Program and leverages the company's position as owner of the world's largest standardized EEG/ERP repository.
Firefly Neuroscience (NASDAQ: AIFF) has announced a new commercial agreement with the Institute of Human Genetics at Heidelberg University Hospital to utilize its FDA-cleared BNA™ Platform in a groundbreaking neuroscience study. The research focuses on investigating the neurophysiological impact of 15q13.3 copy number variants (CNVs).
The study involves analyzing EEG data from 30 subjects (15 with deletions and 15 with duplications) using Firefly's technology through 2026. The company will provide EEG systems, training, and analytical support, comparing results to its proprietary FDA-cleared normative database.
This collaboration builds on previous work between Firefly and Prof. Dr. med. Christian Schaaf, including a joint publication on CHRNA7-related phenotypes, and represents an important step in Firefly's commercial licensing strategy.
Firefly Neuroscience (NASDAQ: AIFF) has acquired Evoke Neuroscience for $6 million, paid 50% in cash and 50% in common stock at $3.50 per share. The acquisition includes a potential $500,000 earn-out in stock if Evoke achieves $3 million in annualized revenues within three years.
The deal significantly expands Firefly's assets, including: a 2x increase in proprietary brain scans to over 180,000 EEG/ERP assessment records, a 3x expansion in granted patents to 27, and a 10x growth in commercial users to over 60. Evoke brings $30 million in historical revenues and extensive EEG/ERP electrophysiology data collection.
This acquisition, combined with Firefly's recent acceptance into the NVIDIA Connect program, advances the company's goal of developing the world's first EEG/ERP-based foundation model of the human brain using its FDA-cleared Brain Network Analytics (BNA™) technology.
Hemostemix (TSXV: HEM) and Firefly Neuroscience (NASDAQ: AIFF) have announced a collaboration to conduct a Phase 1 clinical trial studying ACP-01 as a treatment for vascular dementia. The trial will evaluate brain wave activity in up to 100 patients using Firefly's FDA-Cleared BNA™ platform.
The study will assess patients before treatment and at 3 and 6-month intervals post-treatment. Hemostemix will leverage Firefly's database of 77,000 EEG brain scans across twelve disorders. The trial's primary endpoints include safety assessment, ACP-01 delivery feasibility via intrathecal injection, dosage safety, and tolerability.
Secondary endpoints encompass cognitive functional assessment, clinical dementia rating, quality of life assessment, and MRI analyses of brain volume and blood flow. The exploratory endpoint will use Firefly's BNA™ readout at specified intervals to objectively evaluate ACP-01's efficacy in treating vascular dementia.