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Aldeyra Therapeutics, Inc. - $ALDX STOCK NEWS

Welcome to our dedicated page for Aldeyra Therapeutics news (Ticker: $ALDX), a resource for investors and traders seeking the latest updates and insights on Aldeyra Therapeutics stock.

Aldeyra Therapeutics, Inc. (Nasdaq: ALDX) is a biotechnology company dedicated to improving lives by developing products that treat aldehyde-mediated diseases. The company's mission is to discover and develop innovative therapies designed to tackle immune-mediated diseases. Aldeyra focuses primarily on inflammation, inborn errors of metabolism, and other diseases associated with toxic and pro-inflammatory aldehydes.

Key highlights of Aldeyra's portfolio include:

  • ADX-102: In development for noninfectious anterior uveitis, allergic conjunctivitis, and dry eye disease.
  • Reproxalap: A first-in-class treatment in late-stage development for dry eye disease and allergic conjunctivitis.
  • ADX-2191: A novel methotrexate formulation for proliferative vitreoretinopathy and retinitis pigmentosa.

Aldeyra's approach involves developing pharmaceuticals that modulate immunological systems, optimizing multiple pathways while minimizing toxicity. Recent achievements include positive top-line results from Phase 2 clinical trials and strategic partnerships, such as an exclusive option agreement with AbbVie.

The company is financially stable with sufficient resources projected to fund operations through late 2025, enabling continued advancement of its promising pipeline. Aldeyra’s innovative therapies hold the potential to address significant unmet medical needs in ophthalmology and systemic immune-mediated diseases.

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Aldeyra Therapeutics (Nasdaq: ALDX) has completed enrollment for its Phase 3 clinical trial of Reproxalap, a topical ocular treatment for dry eye disease. The trial, which enrolled 132 patients, aims to assess ocular discomfort and potentially enable a New Drug Application (NDA) resubmission in the second half of 2024. Previous trials showed statistically significant improvements in ocular discomfort when treated with Reproxalap versus a vehicle. Results are expected in Q3 2024. If successful, this could lead to the first dry eye disease label incorporating clinical data on both chronic symptoms and ocular redness.

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Aldeyra Therapeutics (Nasdaq: ALDX) will host an Investor Roundtable Q&A via webcast on Thursday, June 20, 2024, at 8:00 a.m. ET.

This event will feature remarks from Todd C. Brady, M.D., Ph.D., President and CEO, followed by a Q&A session. Shareholders and prospective investors can submit questions via the webcast portal during the event or ahead of time by email starting Monday, June 17.

The live audio webcast and slide presentation will be accessible on the Aldeyra website, with a replay available for 90 days.

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Aldeyra Therapeutics (Nasdaq: ALDX), a clinical-stage biotech firm focused on immune-mediated and metabolic diseases, announced that CEO Todd C. Brady will participate in a fireside chat at the Jefferies Global Healthcare Conference. The event, featuring a discussion with Jefferies' SVP Kelly Shi, is scheduled for 3:30 p.m. ET on June 5, 2024. The company specializes in developing RASP modulators like reproxalap and ADX-2191 for treating conditions such as dry eye disease and retinitis pigmentosa. Webcast details are available on Aldeyra's website, with the session archived for 90 days.

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Aldeyra Therapeutics has enrolled the first patient in a Phase 3 clinical trial for reproxalap in treating dry eye disease, aiming for a potential NDA resubmission by the second half of 2024. The company expects positive results to lead to an NDA resubmission to the FDA, incorporating acute and chronic improvements in symptoms and ocular redness. The planned review period for the resubmission is six months, with promising preliminary data from previous trials.

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Aldeyra Therapeutics highlights recent preclinical data in obesity, atopic dermatitis, pain, and alcoholic hepatitis, and announces a planned pivotal clinical trial in retinitis pigmentosa at the 2024 Research & Development Day. The company presents new preclinical data on investigational RASP modulators in various animal models, showcasing potential treatment opportunities for obesity, dermatitis, pain, and liver conditions. Aldeyra intends to initiate a potentially pivotal Phase 2/3 clinical trial for ADX-2191 in patients with retinitis pigmentosa, supported by positive results from a Phase 2 trial. The company addresses the significant unmet medical need in retinitis pigmentosa and emphasizes the demand for effective treatments in the field.
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Aldeyra Therapeutics, a clinical-stage biotechnology company, will host a Research & Development Day on April 25, 2024, in New York City. The event will showcase pipeline programs and feature presentations from senior leadership.
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Aldeyra Therapeutics, Inc. (ALDX) announces a clinical development plan for resubmission of NDA for reproxalap to treat dry eye disease. The plan includes a dry eye chamber trial in 2024 with potential NDA resubmission in the same year. Positive results could lead to rapid improvement in symptoms of dry eye disease.
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Aldeyra Therapeutics, Inc. (ALDX) announced that its CEO will participate in a fireside chat at the Oppenheimer 34th Annual Healthcare Life Sciences Conference. The virtual conference will take place on February 13-14, 2024. The conversation will be available for live webcast and archived for 90 days.
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Aldeyra Therapeutics, Inc. (Nasdaq: ALDX) announces advancement of its RASP modulator platform, including the expected submission to the FDA of a proposed expansion of the Phase 2 clinical trial of the investigational RASP modulator ADX-629 in Sjögren-Larsson Syndrome to include pediatric patients, initiation of a Phase 2 clinical trial of ADX-629 in moderate alcoholic hepatitis, and submission of IND applications for ADX-246 and ADX-248 for clinical trials in atopic dermatitis and dry age-related macular degeneration patients, respectively.
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Aldeyra Therapeutics, Inc. (Nasdaq: ALDX) announced positive top-line results from a Phase 2 clinical trial of ADX-629, an investigational RASP modulator, in patients with atopic dermatitis. The trial demonstrated statistically significant improvement in EASI, IGA, HAM-D, and POEM scores, with complete resolution of affected body surface area observed in one patient. The company plans to advance ADX-246, a next-generation investigational RASP modulator, to Phase 1/2 clinical testing in healthy volunteers and atopic dermatitis patients.
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FAQ

What is Aldeyra Therapeutics' core business?

Aldeyra Therapeutics focuses on developing innovative therapies designed to treat immune-mediated diseases by modulating immunological systems.

What are some of Aldeyra's key product candidates?

Key product candidates include ADX-102, reproxalap, and ADX-2191, all targeting diseases like dry eye, allergic conjunctivitis, and retinitis pigmentosa.

What recent achievements has Aldeyra Therapeutics accomplished?

The company has reported positive Phase 2 clinical trial results and entered into a strategic partnership with AbbVie.

What is the financial outlook for Aldeyra Therapeutics?

Aldeyra is financially stable, with resources projected to fund operations through late 2025.

How does Aldeyra's approach to drug development differ?

Aldeyra develops pharmaceuticals that modulate immunological systems, optimizing multiple pathways at once while minimizing toxicity.

What is reproxalap?

Reproxalap is a first-in-class treatment for dry eye disease and allergic conjunctivitis, currently in late-stage development.

What diseases does ADX-2191 target?

ADX-2191 targets proliferative vitreoretinopathy and retinitis pigmentosa, both rare retinal diseases with no approved therapies.

What upcoming milestones does Aldeyra anticipate?

Aldeyra anticipates potential NDA submissions and further clinical trial results for its key product candidates in 2024.

What strategic partnerships has Aldeyra entered into?

Aldeyra has an exclusive option agreement with AbbVie for the development and commercialization of reproxalap.

How does Aldeyra Therapeutics impact the field of ophthalmology?

Aldeyra is developing therapies that may provide significant relief for conditions like dry eye disease and retinitis pigmentosa, addressing substantial unmet medical needs in ophthalmology.

Aldeyra Therapeutics, Inc.

Nasdaq:ALDX

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