Alnylam Pharmaceuticals Inc Stock Price, News & Analysis

Alnylam Pharmaceuticals (Nasdaq: ALNY) announced the retirement of Steven Paul, M.D. from its Board of Directors effective April 16, 2022. Dr. Paul has served on the board since September 2010, contributing over 25 years of management experience in the pharmaceutical sector. His leadership has been crucial in guiding Alnylam's growth, including the launch of three products in recent years. CEO Yvonne Greenstreet acknowledged his significant contributions and wished him well in his future endeavors.

Alnylam Pharmaceuticals announced an extension of the New Drug Application (NDA) review for vutrisiran, an investigational treatment for transthyretin-mediated amyloidosis (ATTR). The new Prescription Drug User Fee Act (PDUFA) goal date is July 14, 2022, due to regulatory amendments concerning a third-party packaging facility. No FDA-requested clinical data is pending, and a new facility has been identified. Vutrisiran is also under review by the European Medicines Agency, the Brazilian Health Regulatory Agency, and the Japanese Pharmaceuticals and Medical Devices Agency.

Alnylam Pharmaceuticals (Nasdaq: ALNY) will present an overview of the company at the Stifel 2022 CNS Days on March 28, 2022, at 2:00 pm ET. This presentation will be available via a live audio webcast on the company’s Investors section. A replay will be accessible within 48 hours post-event. Alnylam is a leader in RNA interference therapeutics, aiming to transform treatment for rare and prevalent diseases. The company has a rich pipeline and is committed to delivering innovative medicines through its Alnylam P5x25 strategy.

Alnylam Pharmaceuticals (NASDAQ: ALNY) has filed a lawsuit against Pfizer and Moderna in the U.S. District Court for the District of Delaware, claiming patent infringement related to biodegradable cationic lipids essential for mRNA COVID-19 vaccines, specifically U.S. Patent No. 11,246,933. Alnylam seeks compensation for its patented technology but does not intend to disrupt vaccine production. This legal action highlights Alnylam's investment in RNAi therapeutics, a sector poised for growth and innovation in medicine.

Alnylam Pharmaceuticals (Nasdaq: ALNY) has published its 2021 Corporate Responsibility Report, its first full report, highlighting its GHG emissions and sustainability efforts.

Key points include the establishment of baseline GHG emissions, a strengthened corporate responsibility structure, a $1 million investment in health equity initiatives, and enhanced diversity, equity, and inclusion goals.

Alnylam Pharmaceuticals announced that the FDA has accepted its supplemental New Drug Application (sNDA) for lumasiran, an RNAi therapeutic targeting HAO1, aimed at reducing plasma oxalate in patients with advanced primary hyperoxaluria type 1 (PH1). The FDA has set a PDUFA action date for October 6, 2022. The six-month results from the ILLUMINATE-C study demonstrated significant reductions in plasma oxalate levels for patients, including those on hemodialysis. Alnylam also submitted a Type II Variation to the EMA for lumasiran's label amendment.

Alnylam Pharmaceuticals (Nasdaq: ALNY) will present company overviews at two upcoming conferences: the Cowen 42nd Annual Healthcare Conference on March 8, 2022, at 9:50 am ET, and the Barclays Global Healthcare Conference on March 15, 2022, at 8:00 am ET in Miami, Florida. Live audio webcasts will be accessible on the Investor section of Alnylam's website, with replays available within 48 hours post-event. Alnylam specializes in RNA interference therapeutics, aiming to transform treatment for rare and prevalent diseases.

Alnylam Pharmaceuticals has premiered a documentary titled Two of Me: Living with Porphyria on Rare Disease Day, highlighting the challenges faced by individuals living with acute hepatic porphyria (AHP).

The film aims to raise awareness about AHP, a rare genetic disorder that can take up to 15 years to diagnose, by encouraging viewers to tell 15 others about it.

The documentary focuses on the emotional and psychological impact of AHP, emphasizing the need for better understanding and prompt diagnosis of this debilitating condition.

Alnylam Pharmaceuticals reported impressive financial results for Q4 and the full year 2021, achieving global net product revenues of $199 million and $662 million, representing 83% annual growth compared to 2020. The company anticipates combined net product revenues of $900 million to $1 billion for 2022, indicating 44% growth at the midpoint. Positive results from the HELIOS-A Phase 3 study of vutrisiran demonstrate its potential in treating hATTR amyloidosis. Despite operating losses, Alnylam expects significant upcoming milestones in its product pipeline.