Amarin Reports Third Quarter 2025 Financial Results
Amarin (NASDAQ: AMRN) reported Q3 2025 results showing a shift toward a fully partnered international commercial model and initial margin improvement after a June 2025 global restructuring.
Key Q3 2025 metrics: Total net revenue $49.7M (+17% YoY), Product revenue $48.6M (+16% YoY) driven by U.S. product revenue $40.9M (+34% YoY). Operating loss narrowed to $11.1M (operating margin -22%) from $25.2M year-ago. Net loss was $7.7M ($0.02/share). SG&A fell 47%; restructuring charges of $9.4M were recorded. Cash and investments totaled $286.6M and the company is debt free, targeting sustainable positive free cash flow in 2026.
Amarin (NASDAQ: AMRN) ha riportato i risultati del Q3 2025 che mostrano uno spostamento verso un modello commerciale internazionale interamente partnerizzato e un miglioramento iniziale dei margini dopo la ristrutturazione globale di giugno 2025.
Metriche chiave del Q3 2025: Ricavi netti totali $49,7M (+17% YoY), Ricavi da prodotto $48,6M (+16% YoY) trainati da Ricavi da prodotto negli USA $40,9M (+34% YoY). L’utile operativo è diminuito a $11,1M (margine operativo -22%) rispetto a $25,2M l’anno precedente. La perdita netta è stata $7,7M ($0,02/azione). SG&A è diminuita del 47%; sono stati registrati oneri di ristrutturazione per $9,4M. Le disponibilità liquide e gli investimenti ammontano a $286,6M e l’azienda è senza debiti, mirando a generare flussi di cassa liberi positivi sostenibili nel 2026.
Amarin (NASDAQ: AMRN) informó resultados del 3T 2025 que muestran un cambio hacia un modelo comercial internacional totalmente asociado y una mejora inicial de los márgenes tras la reestructuración global de junio de 2025.
Datos clave del 3T 2025: Ingresos netos totales $49,7M (+17% interanual), Ingresos por producto $48,6M (+16% interanual) impulsados por Ingresos por producto en EE. UU. $40,9M (+34% interanual). La pérdida operativa se redujo a $11,1M (margen operativo -22%) desde $25,2M en el año anterior. La pérdida neta fue $7,7M ($0,02/acción). SG&A cayó 47%; se registraron cargos de reestructuración de $9,4M. Los efectivo y inversiones totalizan $286,6M y la compañía está libre de deudas, apuntando a generar flujo de caja libre positivo sostenible en 2026.
Amarin (NASDAQ: AMRN)은 2025년 3분기 실적에서 국제적인 파트너십 중심의 완전한 해외 상업 모델로의 전환과 2025년 6월 글로벌 구조조정 이후 초기 마진 개선을 보였습니다.
2025년 3분기의 주요 지표: 총 순매출 $49.7M (+전년 동기 대비 17%), 제품 매출 $48.6M (+전년 동기 대비 16%), 미국 내 제품 매출 $40.9M (+전년 동기 대비 34%)에 의해 견인되었습니다. 영업손실은 $11.1M(영업마진 -22%)로 전년의 $25.2M에서 축소되었습니다. 순손실은 $7.7M ($0.02/주당)였습니다. SG&A는 47% 감소했으며, 재구조화 비용으로 $9.4M이 기록되었습니다. 현금 및 투자자산은 총 $286.6M이며 부채가 없는 상태이고, 2026년에는 지속 가능한 긍정적 자유현금흐름을 목표로 하고 있습니다.
Amarin (NASDAQ: AMRN) a publié les résultats du T3 2025 montrant une transition vers un modèle commercial international entièrement en partenariat et une amélioration initiale des marges après la restructuration mondiale de juin 2025.
Principales métriques du T3 2025 : Revenus nets totaux de 49,7 M$ (+17 % YoY), Revenus de produit de 48,6 M$ (+16 % YoY) tirés par les revenus de produit américains de 40,9 M$ (+34 % YoY). La perte opérationnelle s’est réduite à 11,1 M$ (marge opérationnelle -22 %) contre 25,2 M$ l’année précédente. La perte nette était de 7,7 M$ (0,02 $/Action). SG&A a chuté de 47 % ; des charges de restructuration de 9,4 M$ ont été enregistrées. La trésorerie et les investissements s’élèvent à 286,6 M$ et l’entreprise est sans dette, visant à générer un flux de trésorerie disponible positif durable en 2026.
Amarin (NASDAQ: AMRN) meldete die Ergebnisse des Q3 2025, die eine Verschiebung hin zu einem vollständig partnergestützten internationalen Vertriebsmodell und eine erste Margenverbesserung nach der globalen Restrukturierung im Juni 2025 zeigen.
Wichtige Kennzahlen Q3 2025: Gesamtertragsumme $49,7 Mio. (+YoY 17%), Produktumsatz $48,6 Mio. (+YoY 16%) getrieben von US-Produktumsatz $40,9 Mio. (+YoY 34%). Operativer Verlust Verringerte sich auf $11,1 Mio. (operativer Margin -22%) gegenüber $25,2 Mio. im Vorjahr. Nettverlust betrug $7,7 Mio. ($0,02/Aktie). SG&A fiel um 47%; Restrukturierungskosten von $9,4 Mio. wurden verbucht. Bar- und Investitionsmittel beliefen sich auf $286,6 Mio. und das Unternehmen ist schuldenfrei, mit dem Ziel, 2026 einen nachhaltigen positiven freien Cashflow zu erzielen.
Amarin (NASDAQ: AMRN) أصدرت نتائج الربع الثالث 2025 التي تُظهر تحولاً نحو نموذج تجاري دولي قائم على الشراكة بالكامل وتحسنًا أوليًا في الهامش بعد إعادة الهيكلة العالمية في يونيو 2025.
المؤشرات الرئيسية للربع الثالث 2025: إيرادات صافية إجمالية 49.7 مليون دولار (+17% على أساس سنوي), إيرادات المنتج 48.6 مليون دولار (+16% على أساس سنوي) مدفوعة بـ إيرادات منتج الولايات المتحدة 40.9 مليون دولار (+34% على أساس سنوي). تقلصت الخسارة التشغيلية إلى 11.1 مليون دولار (هامش تشغيلي -22%) من 25.2 مليون دولار في العام السابق. الخسارة الصافية كانت 7.7 مليون دولار (0.02 دولار/سهم). انخفض SG&A بنسبة 47%; تم تسجيل أعباء إعادة هيكلة قدرها 9.4 مليون دولار. بلغت السيولة والاستثمارات 286.6 مليون دولار والشركة خالية من الدين، وتستهدف تحقيق تدفق نقدي حقيقي إيجابي مستدام في 2026.
Amarin (纳斯达克股票代码:AMRN) 公布了2025年第三季度业绩,显示出向完全由合作伙伴支撑的国际化商业模式的转变,以及在2025年6月全球重组后 margin 的初步改善。
2025年第三季度的关键指标:总净收入$49.7M(同比增长 17%),产品收入$48.6M(同比增长 16%),由 美国地区产品收入$40.9M(同比增长 34%) 推动。营业亏损收窄至 $11.1M(营业利润率 -22%),较去年同期的 $25.2M。净亏损为 $7.7M($0.02/股)。销售与管理费用下降了 47%;记录了重组费用 $9.4M。现金及投资总额为 $286.6M,公司无债务,目标在2026年实现可持续的正向自由现金流。
- Total net revenue +17% YoY to $49.7M
- U.S. product revenue +34% YoY to $40.9M
- Product revenue +16% YoY to $48.6M
- SG&A reduced 47% reflecting cost discipline
- Operating loss improved 56% to $11.1M
- Debt free with $286.6M cash and investments
- Europe product revenue -5% YoY reflecting transition
- Rest-of-World product revenue -48% YoY
- Restructuring charge $9.4M in Q3 2025
- Sequential cash decline $12.1M from Q2 2025 to Q3 2025
- Operating margin still negative at -22% in Q3 2025
Insights
Q3 shows revenue growth, materially lower operating expenses, and a path to positive free cash flow in
Amarin reported total net revenue of
The company narrowed its operating loss to
The shift to a fully partnered international model coincides with early margin improvement but reduces near-term Europe product revenue.
The new partner-based approach covers ~100 countries and aims to leverage third-party scale; Europe product revenue dipped to
Key dependencies include successful execution of the Recordati transition, partner sell-through, and continued U.S. pricing/volume strength. Monitor quarterly Europe and ROW product revenue trends and licensing receipts over the next 4 quarters and the company’s cash consumption versus its target to reach positive free cash flow in
Company completes transition to fully partnered commercialization model across all international markets
Q3 2025 performance reflects initial impact of new approach to Europe, ongoing expansion of Rest-of-World demand, continued success in managing US market, and initial operating margin improvements following corporate rightsizing
Targeting sustainable positive free cash flow in 2026
DUBLIN and BRIDGEWATER, N.J., Oct. 29, 2025 (GLOBE NEWSWIRE) -- Amarin Corporation plc (NASDAQ: AMRN), a company committed to advancing the science of cardiovascular care worldwide, today announced financial results for the third quarter of 2025.
“With the reporting of Q3 2025 we usher in the next phase in the Amarin story,” said Aaron Berg, President & CEO, Amarin. “Our international commercial strategy is now a fully partnered model comprising seven parties and close to 100 countries with regional and in-country economies of scale, infrastructure and proven experience to commercialize a unique product like VASCEPA®/VAZKEPA® (icosapent ethyl).”
Mr. Berg continued,” We are confident in the strategic actions we have taken at Amarin to date and optimistic about the potential of our global business. Meanwhile, we remain focused on additional ways to create value for shareholders. As always, we look forward to reporting on our future progress.”
Q3 2025 Financial Highlights
| ($ in millions) | Q3 2025 | Q3 2024 | % Change | |||
| Total Net Revenue | ||||||
| Operating Expenses | (20)% | |||||
| Operating Loss Operating Margin % * | (22)% | (60)% | NM | |||
| Net Loss Net Margin | (16)% | (59)% | NM | |||
| Cash | ||||||
| * Operating margin is calculated as operating income (loss) divided by total net revenue. NM – Not Meaningful | ||||||
Commenting on the third quarter and current state of the business, Peter Fishman, Amarin’s Chief Financial Officer said, “Our third quarter performance reflects the initial impact following the strategic steps we’ve taken in creating a different operating profile. Revenues remained stable, supported by ongoing resilience domestically and growing international demand. Operating expenses declined meaningfully, demonstrating the benefits of our global reorganization and continued cost discipline. As we progress with the transition to Recordati, we continue to build toward positive free cash flow, which we expect to achieve in 2026. Overall, with the new strategy and foundation in place, Amarin is positioned for steady operating margin and cash flow improvements."
Q3 2025 Financial Performance
Revenues
| ($ in millions) | Q3 2025 | Q3 2024 | % Change | |||
| Product Revenue, net: | ||||||
| U.S. Europe Rest-of-World (ROW) | (5)% (48)% | |||||
| Total Product Revenue, net | ||||||
| Licensing & Royalties | NM | |||||
| Total Net Revenue | ||||||
| NM - Not Meaningful | ||||||
Total Net Revenue: For Q3 2025, total net revenue increased
Product Revenue, Net: For Q3 2025, product revenue, net increased
Licensing and Royalties: For Q3 2025, licensing and royalties increased
Operating Expenses
| ($ in millions) | Q3 2025 | Q3 2024 | % Change | ||
| COGS | |||||
| SG&A | (47)% | ||||
| R&D | (7)% | ||||
| Restructuring | -- | NM | |||
| Total Operating Expenses * | (20)% | ||||
| * Total operating expenses reflect the sum of SG&A, R&D, and Restructuring expenses. NM - Not Meaningful | |||||
COGS: For Q3 2025, cost of goods sold (COGS) increased
SG&A: For Q3 2025, selling general and administrative expenses decreased
R&D: For Q3 2025, research and development expenses decreased
Restructuring: In Q3 2025, the Company recognized
Total Operating Expenses: For Q3 2025, total operating expenses decreased
Overall, the Company will maintain adequate operating expense levels necessary to support the global VASCEPA/VAZKEPA brand and its partners. Such expenses include: regulatory affairs, nonclinical development, clinical development, biostatistics and data management, medical affairs, medical information, scientific publications, and pharmacovigilance, as well as public company related costs, among others.
Additional Financial Information
Operating Loss: For Q3 2025, the Company reported an operating loss of
Net Loss: For Q3 2025, the Company reported a net loss of
Cash: As of the end of Q3 2025, the Company reported aggregate cash and investments of
Debt: As of the end of Q3 2025, the Company remained debt free.
Third Quarter 2025 Earnings Conference Call and Webcast Information
Amarin will host a conference call on October 29, 2025, at 8:00 a.m. ET to discuss this information. The conference call can be accessed on the investor relations section of the Company's website at www.amarincorp.com, or via telephone by dialing 877-545-0523 within the United States, 973-528-0016 from outside the United States, and referencing conference ID 459510. A replay of the call will be made available for a period of two weeks following the conference call. To listen to a replay of the call, dial 877-481-4010 from within the United States and 919-882-2331 from outside of the United States, and reference conference ID 53008. A replay of the call will also be available through the Company's website shortly after the call.
About Amarin
Amarin is a global pharmaceutical company committed to reducing the cardiovascular disease (CVD) burden for patients and communities and to advancing the science of cardiovascular care around the world. We own and support a global branded product approved by multiple regulatory authorities based on a track record of proven efficacy and safety and backed by robust clinical trial evidence. Our commercialization model includes a direct sales approach in the U.S. and an indirect distribution strategy internationally, through a syndicate of reputable and well-established partners with significant geographic expertise, covering close to 100 markets worldwide. Our success is driven by a dedicated, talented, and highly skilled team of experts passionate about the fight against the world’s leading cause of death, CVD.
About VASCEPA®/VAZKEPA® (icosapent ethyl) Capsules
VASCEPA (icosapent ethyl) capsules are the first prescription treatment approved by the U.S. Food and Drug Administration (FDA) comprised solely of the active ingredient, icosapent ethyl (IPE), a unique form of eicosapentaenoic acid. VASCEPA was launched in the United States in January 2020 as the first drug approved by the U.S. FDA for treatment of the studied high-risk patients with persistent cardiovascular risk despite being on statin therapy. VASCEPA was initially launched in the United States in 2013 based on the drug’s initial FDA approved indication for use as an adjunct therapy to diet to reduce triglyceride levels in adult patients with severe (≥500 mg/dL) hypertriglyceridemia. Since launch, VASCEPA has been prescribed more than twenty-five million times. VASCEPA is covered by most major medical insurance plans. In addition to the United States, VASCEPA is approved and sold in Canada, China, Australia, Lebanon, the United Arab Emirates, Saudi Arabia, Qatar, Bahrain, and Kuwait. In Europe, in March 2021 marketing authorization was granted to icosapent ethyl in the European Union for the reduction of risk of cardiovascular events in patients at high cardiovascular risk, under the brand name VAZKEPA. In April 2021 marketing authorization for VAZKEPA (icosapent ethyl) was granted in the United Kingdom (applying to England, Scotland, Wales, and Northern Ireland). VAZKEPA (icosapent ethyl) is currently approved and sold in Europe in Sweden, Finland, England/Wales, Spain, Netherlands, Scotland, Greece, Portugal, Italy, Denmark and Austria.
United States Indications and Limitation of Use
VASCEPA is indicated:
- As an adjunct to maximally tolerated statin therapy to reduce the risk of myocardial infarction, stroke, coronary revascularization and unstable angina requiring hospitalization in adult patients with elevated triglyceride (TG) levels (≥ 150 mg/dL) and established cardiovascular disease or diabetes mellitus and two or more additional risk factors for cardiovascular disease.
- As an adjunct to diet to reduce TG levels in adult patients with severe (≥ 500 mg/dL) hypertriglyceridemia.
The effect of VASCEPA on the risk for pancreatitis in patients with severe hypertriglyceridemia has not been determined.
Important Safety Information
- VASCEPA is contraindicated in patients with known hypersensitivity (e.g., anaphylactic reaction) to VASCEPA or any of its components.
- VASCEPA was associated with an increased risk (
3% vs2% ) of atrial fibrillation or atrial flutter requiring hospitalization in a double-blind, placebo-controlled trial. The incidence of atrial fibrillation was greater in patients with a previous history of atrial fibrillation or atrial flutter. - It is not known whether patients with allergies to fish and/or shellfish are at an increased risk of an allergic reaction to VASCEPA. Patients with such allergies should discontinue VASCEPA if any reactions occur.
- VASCEPA was associated with an increased risk (
12% vs10% ) of bleeding in a double-blind, placebo-controlled trial. The incidence of bleeding was greater in patients receiving concomitant antithrombotic medications, such as aspirin, clopidogrel or warfarin. - Common adverse reactions in the cardiovascular outcomes trial (incidence ≥
3% and ≥1% more frequent than placebo): musculoskeletal pain (4% vs3% ), peripheral edema (7% vs5% ), constipation (5% vs4% ), gout (4% vs3% ), and atrial fibrillation (5% vs4% ). - Common adverse reactions in the hypertriglyceridemia trials (incidence >
1% more frequent than placebo): arthralgia (2% vs1% ) and oropharyngeal pain (1% vs0.3% ). - Adverse events may be reported by calling 1-855-VASCEPA or the FDA at 1-800-FDA-1088.
- Patients receiving VASCEPA and concomitant anticoagulants and/or anti-platelet agents should be monitored for bleeding.
FULL U.S. FDA-APPROVED VASCEPA PRESCRIBING INFORMATION CAN BE FOUND AT WWW.VASCEPA.COM
Europe
For further information about the Summary of Product Characteristics (SmPC) for VAZKEPA® in Europe, please visit: https://www.ema.europa.eu/en/documents/product-information/vazkepa-epar-product-information_en.pdf
Globally, prescribing information varies; refer to the individual country product label for complete information.
Use of Non-GAAP Adjusted Financial Information
Included in this press release are non-GAAP adjusted financial information as defined by U.S. Securities and Exchange Commission Regulation G. The GAAP financial measure is most directly comparable to each non-GAAP adjusted financial measure used or discussed, and a reconciliation of the differences between each non-GAAP adjusted financial measure and the comparable GAAP financial measure, is included in this press release after the condensed consolidated financial statements.
Non-GAAP adjusted net (loss) income was derived by taking GAAP net loss and adjusting it for non-cash stock-based compensation expense, restructuring expense and other one-time expenses. Management uses these non-GAAP adjusted financial measures for internal reporting and forecasting purposes, when publicly providing its business outlook, to evaluate the company’s performance and to evaluate and compensate the company’s executives. The company has provided these non-GAAP financial measures in addition to GAAP financial results because it believes that these non-GAAP adjusted financial measures provide investors with a better understanding of the company’s historical results from its core business operations.
While management believes that these non-GAAP adjusted financial measures provide useful supplemental information to investors regarding the underlying performance of the company’s business operations, investors are reminded to consider these non-GAAP measures in addition to, and not as a substitute for, financial performance measures prepared in accordance with GAAP. Non-GAAP measures have limitations in that they do not reflect all the amounts associated with the company’s results of operations as determined in accordance with GAAP. In addition, it should be noted that these non-GAAP financial measures may be different from non-GAAP measures used by other companies, and management may utilize other measures to illustrate performance in the future.
Forward-Looking Statements
This press release contains forward-looking statements which are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, including beliefs about Amarin’s key achievements in 2024 and the potential impact and outlook for achievements in 2025 and beyond; Amarin’s 2025 financial outlook and cash position; Amarin’s overall efforts to expand access and reimbursement to VAZKEPA across global markets; expectations regarding potential strategic collaboration and licensing agreements with third parties, including our ability to attract additional collaborators, as well as our plans and strategies for entering into potential strategic collaboration and licensing agreements and the overall potential and future success of VASCEPA/VAZKEPA and Amarin that are based on the beliefs and assumptions and information currently available to Amarin.
All statements other than statements of historical fact contained in this press release are forward-looking statements. These forward-looking statements are not promises or guarantees and involve substantial risks and uncertainties. A further list and description of these risks, uncertainties and other risks associated with an investment in Amarin can be found in Amarin's filings with the U.S. Securities and Exchange Commission, including Amarin’s quarterly report on Form 10-Q for the period ending September 30, 2025 and annual report on Form 10-K for the fiscal year ended 2024. Existing and prospective investors are cautioned not to place undue reliance on these forward-looking statements, which speak only as of the date they are made. Amarin undertakes no obligation to update or revise the information contained in its forward-looking statements, whether as a result of new information, future events or circumstances or otherwise. Amarin’s forward-looking statements do not reflect the potential impact of significant transactions the company may enter into, such as mergers, acquisitions, dispositions, joint ventures or any material agreements that Amarin may enter into, amend or terminate. Investors and others should note that Amarin communicates with its investors and the public using the company website (www.amarincorp.com), the investor relations website (www.amarincorp.com/investor-relations), including but not limited to investor presentations and investor FAQs, U.S. Securities and Exchange Commission filings, press releases, public conference calls and webcasts.
Amarin Contact Information
Media Inquiries:
Tegan Berry
Amarin Corporation plc
PR@amarincorp.com
Investor Inquiries:
Bob Burrows
Western Avenue Advisers LLC
bob.burrows.ext@amarincorp.com
Investor.relations@amarincorp.com
-Tables to Follow-
| CONSOLIDATED BALANCE SHEET DATA | ||||||||||
| (U.S. GAAP) | ||||||||||
| Unaudited | ||||||||||
| September 30, 2025 | December 31, 2024 | |||||||||
| (in thousands) | ||||||||||
| ASSETS | ||||||||||
| Current Assets: | ||||||||||
| Cash and cash equivalents | $ | 122,802 | $ | 121,038 | ||||||
| Restricted cash | 301 | 300 | ||||||||
| Short-term investments | 163,785 | 173,182 | ||||||||
| Net income (loss) for EPS1- non-GAAP | 127,309 | 122,279 | ||||||||
| Inventory | 184,703 | 166,048 | ||||||||
| Prepaid and other current assets | 29,434 | 12,552 | ||||||||
| Total current assets | 628,334 | 595,399 | ||||||||
| Earnings (loss) per Ordinary Share: | 13 | 16 | ||||||||
| Long-term inventory | 9,106 | 64,740 | ||||||||
| Operating lease right-of-use asset | 7,186 | 7,592 | ||||||||
| Other long-term assets | 1,109 | 1,213 | ||||||||
| Earnings (loss) per ADS: | 14,066 | 16,389 | ||||||||
| TOTAL ASSETS | $ | 659,814 | $ | 685,349 | ||||||
| LIABILITIES AND STOCKHOLDERS’ EQUITY | ||||||||||
| Current Liabilities: | ||||||||||
| Accounts payable | $ | 36,712 | $ | 40,366 | ||||||
| Accrued expenses and other current liabilities | 145,521 | 139,583 | ||||||||
| Total current liabilities | 182,233 | 179,949 | ||||||||
| Long-Term Liabilities: | ||||||||||
| Long-term operating lease liability | 6,731 | 7,723 | ||||||||
| Other long-term liabilities | 11,956 | 11,501 | ||||||||
| Total liabilities | 200,920 | 199,173 | ||||||||
| Stockholders’ Equity: | ||||||||||
| Common stock | 310,019 | 305,298 | ||||||||
| Additional paid-in capital | 1,922,351 | 1,914,750 | ||||||||
| Treasury stock | (67,356 | ) | (65,326 | ) | ||||||
| Accumulated deficit | (1,706,120 | ) | (1,668,546 | ) | ||||||
| Total stockholders’ equity | 458,894 | 486,176 | ||||||||
| TOTAL LIABILITIES AND STOCKHOLDERS’ EQUITY | $ | 659,814 | $ | 685,349 | ||||||
| CONSOLIDATED STATEMENTS OF OPERATIONS DATA | |||||||||||||||||
| (U.S. GAAP) | |||||||||||||||||
| Unaudited | |||||||||||||||||
| Three months ended September 30, | Nine months ended September 30, | ||||||||||||||||
| (in thousands, except per share amounts) | (in thousands, except per share amounts) | ||||||||||||||||
| 2025 | 2024 | 2025 | 2024 | ||||||||||||||
| Product revenue, net | $ | 48,558 | $ | 41,852 | $ | 136,210 | $ | 144,522 | |||||||||
| Licensing and royalty revenue | 1,112 | 446 | 28,217 | 21,786 | |||||||||||||
| Total revenue, net | 49,670 | 42,298 | 164,427 | 166,308 | |||||||||||||
| Less: Cost of goods sold | 27,462 | 26,022 | 66,728 | 75,359 | |||||||||||||
| Gross margin | 22,208 | 16,276 | 97,699 | 90,949 | |||||||||||||
| Operating expenses: | |||||||||||||||||
| Selling, general and administrative (1) | 19,697 | 36,904 | 94,944 | 115,340 | |||||||||||||
| Research and development (1) | 4,208 | 4,540 | 14,435 | 14,884 | |||||||||||||
| Restructuring | 9,406 | — | 32,165 | — | |||||||||||||
| Total operating expenses | 33,311 | 41,444 | 141,544 | 130,224 | |||||||||||||
| Operating loss | (11,103 | ) | (25,168 | ) | (43,845 | ) | (39,275 | ) | |||||||||
| Interest income, net | 2,783 | 3,374 | 8,277 | 10,028 | |||||||||||||
| Other income, net | 205 | 265 | 372 | 1,954 | |||||||||||||
| Loss from operations before taxes | (8,115 | ) | (21,529 | ) | (35,196 | ) | (27,293 | ) | |||||||||
| Benefit from (provision for) income taxes | 377 | (3,605 | ) | (2,378 | ) | (6,272 | ) | ||||||||||
| Net loss | $ | (7,738 | ) | $ | (25,134 | ) | $ | (37,574 | ) | $ | (33,565 | ) | |||||
| Loss per Ordinary Share: | |||||||||||||||||
| Basic | $ | (0.02 | ) | $ | (0.06 | ) | $ | (0.09 | ) | $ | (0.08 | ) | |||||
| Diluted | $ | (0.02 | ) | $ | (0.06 | ) | $ | (0.09 | ) | $ | (0.08 | ) | |||||
| Weighted average Ordinary Shares: | |||||||||||||||||
| Basic | 415,531 | 411,150 | 414,607 | 410,786 | |||||||||||||
| Diluted | 415,531 | 411,150 | 414,607 | 410,786 | |||||||||||||
| (1) - Excluding non-cash stock-based compensation, selling, general and administrative expenses were | |||||||||||||||||
| RECONCILIATION OF NON-GAAP NET INCOME (LOSS) | ||||||||||||||||||||
| Unaudited | ||||||||||||||||||||
| Three months ended September 30, | Nine months ended September 30, | |||||||||||||||||||
| (in thousands, except per share amounts) | (in thousands, except per share amounts) | |||||||||||||||||||
| 2025 | 2024 | 2025 | 2024 | |||||||||||||||||
| Net loss for EPS1- GAAP | (7,738 | ) | (25,134 | ) | (37,574 | ) | (33,565 | ) | ||||||||||||
| Stock-based compensation expense | 2,354 | 4,698 | 12,720 | 14,303 | ||||||||||||||||
| ADS Ratio Change Fees | — | — | 2,015 | — | ||||||||||||||||
| Licensing Agreement Fees | — | — | 5,038 | — | ||||||||||||||||
| Restructuring | 9,406 | — | 32,165 | — | ||||||||||||||||
| Net income (loss) for EPS1- non-GAAP | $ | 4,022 | $ | (20,436 | ) | $ | 14,364 | $ | (19,262 | ) | ||||||||||
| 1basic and diluted | ||||||||||||||||||||
| Earnings (loss) per Ordinary Share: | ||||||||||||||||||||
| Basic - non-GAAP | $ | 0.01 | $ | (0.05 | ) | $ | 0.03 | $ | (0.05 | ) | ||||||||||
| Diluted - non-GAAP | $ | 0.01 | $ | (0.05 | ) | $ | 0.03 | $ | (0.05 | ) | ||||||||||
| Earnings (loss) per ADS: | ||||||||||||||||||||
| Basic - non-GAAP | $ | 0.19 | $ | (0.99 | ) | $ | 0.69 | $ | (0.94 | ) | ||||||||||
| Diluted - non-GAAP | $ | 0.19 | $ | (0.99 | ) | $ | 0.69 | $ | (0.94 | ) | ||||||||||
| Weighted average Ordinary Shares: | ||||||||||||||||||||
| Basic | 415,531 | 411,150 | 414,607 | 410,786 | ||||||||||||||||
| Diluted | 416,117 | 411,150 | 415,127 | 410,786 | ||||||||||||||||