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Annovis Appoints Mark Guerin as Chief Financial Officer

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Annovis Bio (NYSE: ANVS), a late-stage clinical drug platform company focused on neurodegenerative diseases, has appointed Mark Guerin as Chief Financial Officer. Guerin brings significant biopharma financial leadership experience, notably serving as CFO at Onconova Therapeutics (now Traws Pharma) where he managed multiple financing transactions.

The appointment comes at a crucial time as Annovis's lead drug candidate buntanetap advances through late-stage clinical development for Alzheimer's and Parkinson's disease. Guerin's extensive background includes roles at Cardiokine and Barrier Therapeutics, where he oversaw key financial operations including IPOs and corporate transactions.

[ "Appointment of experienced CFO with strong track record in biopharma financing", "Lead drug buntanetap showing promise in late-stage clinical development", "Strategic timing of CFO appointment ahead of potential commercialization phase" ]
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Positive

  • None.

Negative

  • Company will need significant financing for late-stage clinical trials
  • Success of buntanetap in larger trials still needs to be proven

News Market Reaction – ANVS

-2.74% 4.8x vol
12 alerts
-2.74% Session close to close
+2.2% Peak Tracked
-6.3% Trough Tracked
$39.06M Market Cap
4.8x Rel. Volume

In the Sep 25 session, ANVS declined 2.74%, reflecting a moderate negative market reaction. Argus tracked a peak move of +2.2% during that session. Argus tracked a trough of -6.3% from its starting point during tracking. Our momentum scanner triggered 12 alerts that day, indicating notable trading interest and price volatility. Trading volume was very high at 4.8x the daily average, suggesting heavy selling pressure.

Data tracked by StockTitan Argus on the day of publication.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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MALVERN, Pa., Sept. 25, 2025 (GLOBE NEWSWIRE) -- Annovis Bio, Inc. (NYSE: ANVS) ("Annovis" or the “Company”), a late-stage clinical drug platform company pioneering transformative therapies for neurodegenerative diseases such as Alzheimer's disease (AD) and Parkinson's disease (PD), today announced the appointment of Mark Guerin, CPA, CMA, CFM, as Chief Financial Officer (CFO) to help lead the Company through a pivotal phase as buntanetap continues to show promise in late-stage clinical development.

Mr. Guerin has extensive experience and a successful track record in managing financial operations within biopharma companies. In 2013, he joined Onconova Therapeutics, now known as Traws Pharma, Inc. (Nasdaq: TRAW), to augment the company’s financial reporting, forecasting, and internal controls following its IPO in July 2013, and was named its CFO in 2016. During his tenure as CFO, Onconova completed several critical financing transactions, including a rights offering, public offerings, registered direct offerings, and at-the-market offerings. Onconova merged with Trawsfynydd Therapeutics, Inc. in April 2024, with concurrent investments from OrbiMed and Torrey Pines, to form Traws Pharma, Inc. and to advance product candidates of both companies in virology and oncology. The company also completed an additional $20 million financing in December 2024.

Prior to joining Onconova, Mr. Guerin worked as an interim senior finance and accounting executive, facilitating post-acquisition integration activities of newly acquired private equity portfolio companies. He also served as Vice President of Finance and CFO at Cardiokine, Inc., overseeing its New Drug Application filing and subsequent sale of the company. Earlier in his career, Mr. Guerin was Director, Financial Reporting and Internal Controls at Barrier Therapeutics, Inc., supporting the company through its IPO and follow-on offering.

Mr. Guerin began his career at Coopers & Lybrand in Philadelphia. He has a bachelor’s degree in accounting from DeSales University and holds CPA, CMA, and CFM professional certifications.

“I am very excited to join the Annovis team at this critical juncture for the company and for patients with neurodegenerative diseases, as buntanetap has demonstrated efficacy in smaller trials and is on track to replicate that success in larger, registrational clinical studies,” commented Mark Guerin, CFO at Annovis. “I look forward to supporting the clinical success of buntanetap and to Annovis delivering a therapeutic solution for patients who need it most.”

About Annovis
Headquartered in Malvern, Pennsylvania, Annovis is dedicated to addressing neurodegeneration in diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD). The Company is committed to developing innovative therapies that improve patient outcomes and quality of life. For more information, visit www.annovisbio.com and follow us on LinkedIn, YouTube, and X.

Investor Alerts
Interested investors and shareholders are encouraged to sign up for press releases and industry updates by registering for email alerts at https://www.annovisbio.com/email-alerts.

Forward-Looking Statements
This press release contains forward-looking statements under the Securities Act of 1933 and the Securities Exchange Act of 1934, as amended. Actual results may differ due to various risks and uncertainties, including those outlined in the Company’s SEC filings under “Risk Factors” in its Annual Report on Form 10-K and Quarterly Reports on Form 10-Q. The Company undertakes no obligation to update forward-looking statements except as required by law.

Contact Information:
Annovis Bio Inc.
101 Lindenwood Drive
Suite 225
Malvern, PA 19355
www.annovisbio.com

Investor Contact:
Alexander Morin, Ph.D.
Director, Strategic Communications
Annovis Bio
ir@annovisbio.com


FAQ

Who is the new CFO of Annovis Bio (NYSE: ANVS)?

Mark Guerin, CPA, CMA, CFM, has been appointed as the new Chief Financial Officer of Annovis Bio. He previously served as CFO at Onconova Therapeutics (now Traws Pharma).

What is Annovis Bio's main drug candidate?

Annovis Bio's main drug candidate is buntanetap, which is in late-stage clinical development for treating Alzheimer's disease and Parkinson's disease.

What experience does Mark Guerin bring to Annovis Bio?

Mark Guerin brings extensive experience in biopharma financial operations, including managing IPOs, public offerings, and corporate transactions at companies like Onconova Therapeutics, Cardiokine, and Barrier Therapeutics.

Why is this CFO appointment significant for Annovis Bio (ANVS)?

The appointment comes at a critical time as the company's lead drug buntanetap advances through late-stage clinical trials, with Guerin's experience in financing and public offerings being crucial for potential commercialization.

What diseases is Annovis Bio targeting with its drug development?

Annovis Bio is developing treatments for neurodegenerative diseases, specifically Alzheimer's disease (AD) and Parkinson's disease (PD).