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Aptose Biosciences Announces Results of Annual Meeting of Shareholders

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SAN DIEGO and TORONTO, June 02, 2020 (GLOBE NEWSWIRE) -- Aptose Biosciences Inc. (“Aptose” or the “Company”) (NASDAQ: APTO, TSX: APS), a clinical-stage company developing highly differentiated therapeutics that target the underlying mechanisms of cancer, today announced the voting results from the Company’s annual meeting of shareholders held today, June 2, 2020, in (the “Meeting”). A total of 73.21% of the issued and outstanding common shares of the Company were represented by shareholders present or represented by proxy at the Meeting.

The Company is pleased to announce that all of the nominees listed in the proxy statement dated April 24, 2020 were elected as Directors.  The results of the vote are detailed below:

100%; border-collapse:collapse !important;">
20%; width:20%; min-width:20%;">Nominee20%; width:20%; min-width:20%;">Votes For20%; width:20%; min-width:20%;">% Votes
For
20%; width:20%; min-width:20%;">Votes
Withheld
20%; width:20%; min-width:20%;">% Votes
Withheld
Ms. Carol G. Ashe 
Dr. Denis Burger 
Ms. Caroline M. Loewy
Dr. Erich Platzer 
Dr. William G. Rice 
Dr. Mark D. Vincent 
Mr. Warren Whitehead 
31,350,450
27,579,743
31,350,772
31,357,321
31,260,354
31,358,492
31,358,562
99.84
87.83
99.84
99.86
99.56
99.87
99.87
49,262
3,819,969
48,940
42,391
139,358
41,220
41,150
0.16
12.17
0.16
0.14
0.44
0.13
0.13

Aptose shareholders also voted to re-appoint KPMG LLP as the independent registered public accounting firm of the Company.

Please refer to the Company’s management proxy circular available on SEDAR at www.sedar.com or EDGAR https://www.sec.gov/edgar.shtml for more details on the matters covered at the Meeting.  Final voting results on all matters voted on at the Meeting will also be filed on SEDAR and EDGAR.

About Aptose Biosciences

Aptose Biosciences is a clinical-stage biotechnology company committed to developing personalized therapies addressing unmet medical needs in oncology, with an initial focus on hematology. The Company's small molecule cancer therapeutics pipeline includes products designed to provide single agent efficacy and to enhance the efficacy of other anti-cancer therapies and regimens without overlapping toxicities. The Company has two clinical-stage investigational products for hematologic malignancies: CG-806, an oral, first-in-class mutation-agnostic FLT3/BTK kinase inhibitor, is in a Phase 1 trial in patients with relapsed or refractory B cell malignancies, including chronic lymphocytic leukemia (CLL), small lymphocytic lymphoma (SLL) and non-Hodgkin lymphoma (NHL), who have failed or are intolerant to standard therapies; APTO-253, the only clinical stage agent that directly targets the MYC oncogene and suppresses its expression, is in a Phase 1b clinical trial for the treatment of patients with relapsed or refractory acute myeloid leukemia (AML) or high risk myelodysplastic syndrome (MDS). For further information, please visit www.aptose.com.

For further information, please contact:

100%; border-collapse:collapse !important;">
40%; width:40%; min-width:40%;">Aptose Biosciences Inc. 
Greg Chow  
Executive Vice President, CFO
858-926-2730 
gchow@aptose.com
60%; width:60%; min-width:60%;">LifeSci Advisors, LLC
Dan Ferry, Managing Director
617-535-7746
Daniel@LifeSciAdvisors.com

SMP Communications

Susan Pietropaolo
201-923-2049
susan@smpcommunications.com
 

Aptose Biosciences Inc.

NASDAQ:APTO

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Biological Product (except Diagnostic) Manufacturing
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United States of America
TORONTO

About APTO

aptose biosciences is a science-driven biotechnology company advancing first-in-class agents to treat life-threatening cancers, such as acute myeloid leukemia (aml), high-risk myelodysplastic syndromes (mds) and other hematologic malignancies. based on insights into the genetic and epigenetic profiles of certain cancers and patient populations, aptose is building a pipeline of novel oncology therapies directed at dysregulated processes and signaling pathways. aptose is developing targeted medicines for precision treatment of these diseases, based on a patient’s specific gene expression signature. in the treatment of cancer, this strategy is intended to optimize efficacy and quality of life by minimizing the cytotoxic side effects associated with conventional therapies. cg026806 (cg’806) is a highly potent first-in-class pan-flt3/btk inhibitor. this small molecule therapeutic agent, exhibits a picomolar ic50 toward the fms-like tyrosine kinase 3 with the internal tandem duplication (flt