Welcome to our dedicated page for Aptevo Therapeutics news (Ticker: APVO), a resource for investors and traders seeking the latest updates and insights on Aptevo Therapeutics stock.
Aptevo Therapeutics Inc. (NASDAQ: APVO) is a clinical-stage biotechnology company developing bispecific and trispecific immunotherapies for cancer, and its news flow reflects both scientific progress and capital markets activity. On this APVO news page, readers can follow company-issued updates and third-party coverage related to its immune-oncology pipeline and corporate developments.
Aptevo’s recent press releases highlight key milestones for mipletamig, its CD123 x CD3 T-cell engager in the RAINIER Phase 1b/2 trial for frontline acute myeloid leukemia. News items include reports of remission rates in early cohorts, safety observations such as the absence of cytokine release syndrome in frontline patients treated to date in reported cohorts, and presentations of data at major medical meetings like the American Society of Hematology (ASH).
Investors and clinicians can also track announcements on Aptevo’s expanding CD3-engaging portfolio, including bispecific candidates APVO442 (PSMA x CD3) for prostate cancer and APVO455 (Nectin-4 x CD3) for multiple solid tumor types, as well as trispecific candidates APVO451 and APVO452 that combine tumor targeting, T-cell activation, and CD40-mediated costimulation. News coverage often details preclinical data presented at scientific conferences such as the Society for Immunotherapy of Cancer (SITC).
In addition to R&D and clinical trial updates, APVO news includes quarterly financial results, descriptions of its cash runway, and disclosures about equity financings, including at-the-market offerings, registered direct offerings, and an equity line of credit structure. Regulatory and governance developments, such as reverse stock split implementation, Nasdaq compliance updates, and amendments to rights agreements, are also reported.
By reviewing the APVO news feed, readers can monitor how Aptevo communicates progress on its ADAPTIR and ADAPTIR-FLEX platform-derived candidates, its interactions with the capital markets, and its participation in scientific and industry conferences.
Aptevo Therapeutics (NASDAQ: APVO) released its second quarter 2020 financial results, reporting a net loss of $6.8 million or $2.10 per share, a significant decrease from a $13.3 million loss in Q2 2019. The company generated $0.5 million in royalty revenue from Pfizer's RUXIENCE sales, marking its entry into non-dilutive revenue streams. Cash and equivalents stood at $10.2 million, bolstered by a $25 million loan, ensuring operations through Q3 2021. Clinical developments include completion of cohort 6 in the APVO436 trial for AML and high-grade MDS, with promising preclinical data for ALG.APV-527.
Aptevo Therapeutics (NASDAQ: APVO) announced advancements in its clinical trial for APVO436 treating Acute Myeloid Leukemia (AML) and High-Grade Myelodysplastic Syndrome (MDS), completing cohort 6 enrollment. The company reported $0.5 million in royalty revenue from Pfizer's RUXIENCE sales and extended its cash runway into Q3 2021 through a $25 million loan. The net loss narrowed to $6.8 million in Q2 2020 from $13.3 million in Q2 2019. Preclinical data for ALG.APV-527 suggests a favorable safety profile, with further development opportunities being explored.