Welcome to our dedicated page for Autolus Therapeutics news (Ticker: AUTL), a resource for investors and traders seeking the latest updates and insights on Autolus Therapeutics stock.
Autolus Therapeutics plc reports news on its commercial-stage biopharmaceutical business developing, manufacturing and delivering next-generation programmed T cell therapies. Updates center on AUCATZYL (obecabtagene autoleucel, or obe-cel), product revenue, manufacturing capacity, gross margin plans and the company’s acute lymphoblastic leukemia business.
Company announcements also cover clinical programs using obe-cel and related T cell therapy candidates in pediatric relapsed/refractory acute lymphoblastic leukemia, lupus nephritis and progressive multiple sclerosis. Other recurring items include financial results, operational efficiency actions, investor presentations, Nasdaq inducement equity grants and ADR-related public-company disclosures.
Autolus Therapeutics plc (Nasdaq: AUTL) has successfully closed a public offering of 16,428,572 ADSs at a price of $7.00 each, raising approximately $115 million in gross proceeds. The offering included the full exercise of an option by underwriters for an additional 2,142,857 ADSs. J.P. Morgan and Wells Fargo Securities were the joint bookrunners for this transaction. The funds will support the development of Autolus' next-generation T cell therapies aimed at treating cancer, leveraging advanced programming technologies to improve efficacy against malignancies.
Autolus Therapeutics plc (Nasdaq: AUTL) has priced a public offering of 14,285,715 American Depositary Shares (ADSs) at $7.00 each, aiming to raise approximately $100 million. The offering is expected to close on February 12, 2021, pending customary conditions. Additionally, underwriters have a 30-day option to purchase up to 2,142,857 ADSs.
This offering follows an effective shelf registration statement with the SEC, and all securities will be offered solely through a prospectus. Autolus is focused on developing advanced T cell therapies for cancer treatment.
Autolus Therapeutics plc (Nasdaq: AUTL) has announced a public offering of up to $100 million of its American Depositary Shares (ADSs). The offering, managed by J.P. Morgan and Wells Fargo Securities, may include an additional $15 million option for underwriters. This move is part of the company's strategy to support its development of next-generation T cell therapies for cancer. The offering is subject to market conditions, with no assurance regarding completion or terms.
Autolus Therapeutics (Nasdaq: AUTL) will disclose its Q4 2020 and full-year financial results on March 4, 2021, prior to U.S. market open. The company develops next-generation programmed T cell therapies and is expected to provide operational highlights during this release. A conference call will occur at 8:30 am ET, featuring a general business update and an opportunity for investors to engage. For those interested, access to the call will be available via the company’s website and dedicated phone lines.
Autolus Therapeutics plc (Nasdaq: AUTL) is prioritizing its CAR T cell therapy, AUTO1, targeting Adult Acute Lymphoblastic Leukemia (ALL). Key data from the AUTO1-AL1 study is expected in 2022. The company aims to partner its AUTO3 program and adjust its workforce by approximately 20%, anticipating annual cash savings of about $15 million. AUTO1 demonstrated promising results with a 52% event-free survival at 12 months. Autolus is advancing its pipeline focused on oncology, aiming for pivotal data and exploring additional B-cell malignancies.
Autolus Therapeutics plc (Nasdaq: AUTL) announced participation in investor conferences in January 2021. Key events include:
- 11 January 2021 - Presentation at the H.C. Wainwright BioConnect 2021 Conference available on demand from 6:00 am ET.
- 13 January 2021 - Presentation at the 39th Annual J.P. Morgan Healthcare Conference at 9:10 am ET, with virtual meetings and a live webcast.
Archived replays will be accessible for 30 days post-conferences. Autolus develops innovative T cell therapies for cancer treatment.
Autolus Therapeutics (AUTL) announced progress on its CAR T product candidate AUTO3 at the ASH Annual Meeting. The ALEXANDER study, focusing on relapsed/refractory diffuse large B cell lymphoma, showed AUTO3 to be well tolerated, with low rates of cytokine release syndrome and neurotoxicity. The overall objective response rate was 65%, with a complete response rate of 51%. Notably, higher dosing improved outcomes, with an 87% response rate at the highest dose. The company is evaluating a strategy to optimize AUTO3's development path and will provide updates in Q1 2021.
Autolus Therapeutics announced promising results from its AUTO1 CAR T cell therapy in the ongoing ALLCAR Phase 1 study for adult patients with relapsed/refractory B-Acute Lymphocytic Leukemia (ALL). As of November 12, 2020, 20 patients had received AUTO1, showing a tolerance profile with no Grade 3 cytokine release syndrome. Among evaluable patients, 84% achieved minimal residual disease-negative complete response at one month, with encouraging overall survival rates. The pivotal Phase 1b/2 study is anticipated to enroll patients throughout 2021, with full data expected in 2022.
Autolus Therapeutics (AUTL) has announced promising results from a Phase 1 study of AUTO6, a GD2-targeting CAR T therapy. The study demonstrated rapid regression of solid tumors in children without causing neurotoxicity, a common side effect of similar therapies. All six patients in higher dosage cohorts displayed CAR T cell expansion and partial response. The company aims to enhance AUTO6's effectiveness with AUTO6NG, which is expected to enter clinical trials in 2021. The study underscores the potential of CAR T cells against advanced solid cancers, highlighting significant implications for neuroblastoma treatment.
Autolus Therapeutics (Nasdaq: AUTL) announced an upcoming investor conference call to discuss AUTO1 and AUTO3 data from the ASH Virtual Congress 2020. The call will feature Dr. Christian Itin, CEO, who will engage in a fireside chat at the Jefferies Virtual London Healthcare Conference on November 19, 2020, at 11:25 PM ET. Additionally, on December 7, 2020, the team will present their findings on CAR T cell therapies for adult Acute Lymphoblastic Leukemia and relapsed/refractory diffuse large B cell lymphoma. Webcasts of the events will be available on their website.