Avantor® Unveils Next-Generation Sterile Sampling Platform and PUPSIT Assemblies
Avantor (NYSE: AVTR) on October 30, 2025 launched a next-generation sterile sampling platform and pre-engineered PUPSIT assemblies to streamline bioprocessing qualification and in-process decision-making.
The suite includes NBSS (needle-based), NFSS (needle-free), EVSS (exact-volume sampling) and OmniTop, offering modular multi-sample configurations, closed-path designs, standardized bills of materials, and supplier-agnostic PUPSIT assemblies that integrate with common filtration trains to reduce line breaks, operator intervention, and setup variability.
Avantor says the products support single-use and hybrid facilities across clinical to commercial scale, aiming to improve product protection, operational safety, and speed of decisions.
Avantor (NYSE: AVTR) il 30 ottobre 2025 ha lanciato una piattaforma di campionamento sterile di ultima generazione e assemblaggi PUPSIT pre-ingegnerizzati per snellire la qualificazione dei bioprocessi e la decisione in-process.
La suite include NBSS (basato su ago), NFSS (senza ago), EVSS (campionamento a volume esatto) e OmniTop, offrendo configurazioni modulari multi-campione, progetti a percorso chiuso, distinte basi standardizzate e assemblaggi PUPSIT agnostici al fornitore che si integrano con linee di filtrazione comuni per ridurre spezzature di linea, intervento dell'operatore e variabilità nell'allestimento.
Avantor afferma che i prodotti supportano strutture usa-e-getta e ibride dalla clinica alla scala commerciale, mirando a migliorare la protezione del prodotto, la sicurezza operativa e la velocità delle decisioni.
Avantor (NYSE: AVTR) el 30 de octubre de 2025 lanzó una plataforma de muestreo estéril de próxima generación y ensamblajes PUPSIT preengenierados para optimizar la calificación de bioprocesos y la toma de decisiones en proceso.
La suite incluye NBSS (con aguja), NFSS (sin aguja), EVSS (muestreo de volumen exacto) y OmniTop, ofreciendo configuraciones modulares de múltiples muestras, diseños de recorrido cerrado, listas de materiales estandarizadas y ensamblajes PUPSIT independientes del proveedor que se integran con trenes de filtración comunes para reducir fallos de línea, intervención de operarios y variabilidad en la configuración.
Avantor afirma que los productos soportan instalaciones de un solo uso y híbridas desde clínico hasta escala comercial, con el objetivo de mejorar la protección del producto, la seguridad operativa y la velocidad de las decisiones.
Avantor (NYSE: AVTR)는 2025년 10월 30일에 차세대 멸균 샘플링 플랫폼과 예비 설계된 PUPSIT 어셈블리를 출시하여 생물공정 자격인증 및 프로세스 중 의사결정을 간소화했습니다.
이 suite에는 NBSS (바늘 기반), NFSS (바늘 없는), EVSS (정확 부피 샘플링) 및 OmniTop이 포함되어 모듈식 멀티 샘플 구성, 클로즈드 루프 디자인, 표준화된 자재 명세서, 그리고 공급업체에 구애받지 않는 PUPSIT 어셈블리가 일반 필터링 트레인과 통합되어 생산 라인 중단, 작업자 개입, 설정 가변성을 줄입니다.
Avantor는 이 제품들이 임상에서 상업 규모까지의 단일 사용 및 하이브리드 시설을 지원한다고 말하며, 제품 보호, 운영 안전성 및 의사결정 속도 향상을 목표로 합니다.
Avantor (NYSE: AVTR) a lancé le 30 octobre 2025 une plateforme d'échantillonnage stérile de nouvelle génération et des ensembles PUPSIT pré-conçus pour rationaliser la qualification des bioprocédés et la prise de décision en cours de procédé.
La suite comprend NBSS (à aiguille), NFSS (sans aiguille), EVSS (échantillonnage à volume exact) et OmniTop, offrant des configurations modulaires multi-échantillons, des conceptions à trajet fermé, des nomenclatures standardisées et des assemblages PUPSIT indépendants du fournisseur qui s'intègrent aux trains de filtration courants pour réduire les arrêts de ligne, l'intervention de l'opérateur et la variabilité de mise en place.
Avantor affirme que les produits prennent en charge les installations à usage unique et hybrides, de la clinique à l'échelle commerciale, dans le but d'améliorer la protection des produits, la sécurité opérationnelle et la rapidité des décisions.
Avantor (NYSE: AVTR) hat am 30. Oktober 2025 eine neu generation sterile Probenahmeplattform und vorgefertigte PUPSIT- Baugruppen eingeführt, um die Qualifizierung von Bioprozessen und die Entscheidungsfindung im Prozess zu rationalisieren.
Die Suite umfasst NBSS (Nadel-basiert), NFSS (Nadelfrei), EVSS (Präzises Volumenprobenahme) und OmniTop, bietet modulare Multi-Sample-Konfigurationen, Closed-Path-Designs, standardisierte Stücklisten und herstellerunabhängige PUPSIT-Baugruppen, die sich in gängige Filtrationszüge integrieren, um Anlagenunterbrechungen, Eingriffe von Bedienern und Einrichtungsvariabilität zu verringern.
Avantor sagt, dass die Produkte Einweg- und Hybridanlagen von der klinischen bis zur kommerziellen Skala unterstützen und darauf abzielen, den Produktschutz, die Betriebssicherheit und die Entscheidungsfindung zu verbessern.
Avantor (NYSE: AVTR) في 30 أكتوبر 2025 أطلقت منصة أخذ عينات معقمة من الجيل التالي وتجميعات PUPSIT معدة مسبقاً لتبسيط تأهيل عمليات البيوبروسيز واتخاذ القرار أثناء العملية.
تشمل المجموعة NBSS (قابلة للإبرة)، NFSS (بدون إبرة)، EVSS (أخذ عينات بالحجم الدقيق) وOmniTop، وتوفر تكوينات متعددة العينات قابلة للتعديل، وتصاميم مسار مغلق، وقوائم مواد موحدة وتجميعات PUPSIT مستقلة عن المورد تتكامل مع خطوط الترشيح الشائعة لتقليل توقف الخط، وتدخل المشغل، وعدم الاتساق في الإعداد.
وتقول Avantor إن المنتجات تدعم مرافق الاستخدام الأحادي والهجين من العيادة إلى المقياس التجاري، مع هدف تحسين حماية المنتج، وسلامة التشغيل، وسرعة اتخاذ القرار.
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Insights
Avantor launched a configurable sterile sampling and PUPSIT product suite to simplify qualification and reduce contamination risk.
Avantor bundles modular sampling systems (NBSS, NFSS, EVSS, OmniTop) with pre-engineered PUPSIT assemblies to create a closed, standardized flow path from vessel to filter to sample. These products aim to reduce operator interventions, minimize line breaks, and shorten qualification steps by providing standardized bills of materials and documentation that support site-to-site consistency.
Success depends on customer adoption, integration with existing filtration trains, and regulatory qualification at each user site; the announcement cites supplier-agnostic connectivity and closed-path designs but provides no adoption metrics. Implementation risks include the need for local qualification and potential process-specific customization despite the pre-engineered approach.
Watch for customer qualification activity and deployment across clinical and commercial sites following the
Integrated sterile sampling and PUPSIT solutions streamline bioprocessing, enhance flexibility, and reduce risk while accelerating in-process decisions
Avantor's sterile sampling suite addresses common bioproduction needs through modular, multi-sample configurations that minimize line breaks and operator intervention. Standardized bills of materials and documentation streamline setup and qualification, while closed-path designs protect sample integrity. By tailoring components and connection formats to each process, customers can standardize across sites and scales, reducing variability and the need for custom engineering.
The suite includes:
- NBSS (Needle-Based Sampling System): Enables closed, aseptic sampling from stainless-steel vessels using a needle interface.
- NFSS (Needle-Free Sampling System): A closed, needle-free alternative that enhances operator safety and ease of use while maintaining sampling accuracy and efficiency. Both NBSS and NFSS support multi-sample formats and flexible collection options including bags, bottles, and conical tubes.
- EVSS (Exact Volume Sampling System): Provides closed, precise small-volume sampling ideal for cell and gene therapy applications where accuracy and material conservation are essential.
- OmniTop: Offers weld-on or aseptic connection to process vessels with flexible chamber options, supporting routine sampling requirements with added versatility.
Avantor's pre-engineered, configurable PUPSIT assemblies integrate supplier-agnostic components that connect seamlessly with common filtration trains. By standardizing integrity testing after sterilization and maintaining closed flow paths, these assemblies simplify implementation, reduce setup variability, and minimize the need for ad hoc rigging — helping manufacturers streamline PUPSIT qualification while maintaining full compliance.
Together, the sterile sampling suite and PUPSIT assemblies create a consistent, closed pathway from vessel to filter to sample, helping biomanufacturers protect product quality, improve operational safety, reduce risk, and accelerate decision-making across single-use and hybrid facilities, from clinical to commercial scale.
"Biopharmaceutical manufacturers need solutions that are configurable, easy to implement, and consistently perform across scales," said Benoit Gourdier, Executive Vice President, Bioscience Production, Avantor. "The new products we highlighted at CPHI meet these core needs—from established biologics to emerging advanced therapies—helping customers strengthen process control and bring therapies to patients with greater reliability and speed."
The newly launched NFSS and EVSS, combined with existing OmniTop and NBSS, makes Avantor's sampling platform one of the most comprehensive solutions for any bioprocessing sampling application. Contact your Avantor representative or visit Avantorsciences.com for more information.
About Avantor
Avantor® is a leading life science tools company and global provider of mission-critical products and services to the life sciences and advanced technology industries. We work side-by-side with customers at every step of the scientific journey to enable breakthroughs in medicine, healthcare, and technology. Our portfolio is used in virtually every stage of the most important research, development and production activities at more than 300,000 customer locations in 180 countries. For more information, visit avantorsciences.com and find us on LinkedIn, X (Twitter) and Facebook.
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Eric Van Zanten
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Avantor
610-529-6219
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SOURCE Avantor and Financial News
FAQ
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