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Avalo Therapeutics to Join the Russell 2000® and Russell 3000® Indexes

(Positive)
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Avalo Therapeutics (Nasdaq: AVTX), a clinical-stage biotech focused on IL-1β pathway therapies for immune-mediated inflammatory diseases, will join the Russell 2000 and Russell 3000 indexes.

Inclusion is effective after the close of U.S. equity markets on June 26, 2026, increasing exposure to index-based and benchmark-driven investors.

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Positive

  • Inclusion in Russell 2000 index effective June 26, 2026
  • Inclusion in broad-market Russell 3000 index
  • Increased visibility among index funds and institutional managers using Russell benchmarks

Negative

  • None.

News Market Reaction – AVTX

+1.11%
+1.11% Session close to close

In the Jun 26 session, AVTX gained 1.11%, reflecting a mild positive market reaction.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement adds AVTX to the Russell 2000 and 3000, potentially broadening institutional aware...
Analysis

This announcement adds AVTX to the Russell 2000 and 3000, potentially broadening institutional awareness via index funds. With an active shelf and notable short interest, investors may watch how added visibility interacts with future financing decisions and positioning.

Key Figures

Index constituents: 3,000 companies Market coverage: 96% of investable U.S. equity market Index inclusion date: June 26, 2026
3 metrics
Index constituents 3,000 companies Largest 3,000 publicly traded U.S. companies in the Russell 3000 Index
Market coverage 96% of investable U.S. equity market Portion of U.S. equity market represented by the Russell 3000 Index
Index inclusion date June 26, 2026 Effective after U.S. market close for Russell 2000 and 3000 additions

Historical Context

5 past events · Latest: Jun 23 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Jun 23 Board appointment Positive +4.4% Added an experienced biopharma executive to the board after recent pipeline progress.
Jun 16 Pipeline expansion Positive -1.9% Advanced AVTX-010, a next‑generation anti‑IL‑1β antibody, expanding the HS pipeline.
May 22 Inducement option grant Neutral -2.0% Granted 34,000 stock options to a new employee under Nasdaq inducement rules.
May 13 Earnings and updates Positive -0.5% Reported positive Phase 2 LOTUS data and stronger cash from a large equity raise.
May 05 Equity offering Negative +34.1% Priced a sizeable public equity and pre‑funded warrant offering for Phase 3 funding.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

AVTX often shows price moves that diverge from the apparent positivity of its news flow.

Key Terms

russell 2000® index, russell 3000® index
2 terms
russell 2000® index financial
"it will be added to the small-cap Russell 2000® Index and the broad-market"
A stock market index that tracks the performance of roughly 2,000 publicly traded U.S. companies with smaller market values, representing the broader small-cap segment of the market. It matters to investors because it acts like a thermometer for smaller companies—used as a benchmark to compare fund performance, guide portfolio allocation, and gauge economic or market trends affecting growth-oriented, higher-risk firms.
russell 3000® index financial
"it will be added to the small-cap Russell 2000® Index and the broad-market Russell 3000® Index"
A broad stock market index that tracks the performance of about 3,000 publicly traded U.S. companies of all sizes, acting as a wide-ranging snapshot of the U.S. equity market. It matters to investors because it serves as a common yardstick for the overall market’s health and is the basis for many index funds and investment strategies—think of it as a single basket that shows how the whole U.S. stock market is doing.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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WAYNE, Pa., June 26, 2026 (GLOBE NEWSWIRE) -- Avalo Therapeutics, Inc. (Nasdaq: AVTX), a clinical stage biotechnology company fully dedicated to developing therapeutics targeting the IL-1β pathway for immune-mediated inflammatory diseases, today announced that it will be added to the small-cap Russell 2000® Index and the broad-market Russell 3000® Index, effective after the close of U.S. equity markets on June 26, 2026.

The Russell 3000® Index measures the performance of the largest 3,000 publicly traded U.S. companies, representing approximately 96% of the investable U.S. equity market. The Russell 2000® Index is a subset of the Russell 3000® Index and serves as the leading benchmark for U.S. small-cap equities. The Russell Indexes are used by investment managers and institutional managers for index funds and as benchmarks for active investment strategies.

For more information on the Russell 3000® Index and Russell 2000® Index and the Russell indexes reconstitution, visit the “Russell Reconstitution” section on the FTSE Russell website.

About Avalo Therapeutics

Avalo Therapeutics is a clinical stage biotechnology company fully dedicated to developing therapeutics targeting the IL-1β pathway for immune-mediated inflammatory diseases. Our lead asset, abdakibart, is an anti-IL-1β monoclonal antibody (mAb). Positive topline data was recently reported for abdakibart in a Phase 2 clinical trial in hidradenitis suppurativa (HS). In addition to HS, we’re exploring additional opportunities to make an impact in prevalent indications that have significant remaining unmet needs. We are also advancing AVTX-010, a long-acting next-generation anti-IL-1β mAb designed to extend dosing intervals and build upon the differentiated profile established by abdakibart. For more information about Avalo, please visit www.avalotx.com.

Forward-Looking Statements

This press release may include forward-looking statements made pursuant to the Private Securities Litigation Reform Act of 1995. Forward-looking statements are statements that are not historical facts. Such forward-looking statements are subject to significant risks and uncertainties that are subject to change based on various factors (many of which are beyond Avalo’s control), which could cause actual results to differ from the forward-looking statements. Such statements may include, without limitation, statements with respect to Avalo’s plans, objectives, projections, expectations and intentions and other statements identified by words such as “projects,” “may,” “might,” “will,” “could,” “would,” “should,” “continue,” “seeks,” “aims,” “predicts,” “believes,” “expects,” “anticipates,” “estimates,” “intends,” “plans,” “potential,” or similar expressions (including their use in the negative), or by discussions of future matters such as: drug development costs, timing of trials and trial results and other risks, including reliance on investigators and enrollment of patients in clinical trials; reliance on key personnel; regulatory risks; general economic and market risks and uncertainties, including those caused by the war in Ukraine and the Middle East; and those other risks detailed in Avalo’s filings with the Securities and Exchange Commission, available at www.sec.gov. Actual results may differ from those set forth in the forward-looking statements. Except as required by applicable law, Avalo expressly disclaims any obligations or undertaking to release publicly any updates or revisions to any forward-looking statements contained herein to reflect any change in Avalo’s expectations with respect thereto or any change in events, conditions or circumstances on which any statement is based.

For media and investor inquiries

Christopher Sullivan, CFO
Avalo Therapeutics, Inc.
ir@avalotx.com
410-803-6793

or

Meru Advisors
Lauren Glaser
lglaser@meruadvisors.com 


FAQ

What did Avalo Therapeutics (AVTX) announce about the Russell indexes on June 26, 2026?

Avalo Therapeutics announced its addition to the Russell 2000 and Russell 3000 indexes, effective after the U.S. market close on June 26, 2026. According to Avalo Therapeutics, this reflects its status among publicly traded U.S. companies.

When will Avalo Therapeutics (AVTX) be added to the Russell 2000 and Russell 3000 indexes?

Avalo Therapeutics will be added to the Russell 2000 and Russell 3000 indexes after the close of U.S. equity markets on June 26, 2026. According to Avalo Therapeutics, this timing aligns with the Russell indexes’ annual reconstitution.

What does Russell 2000 index inclusion mean for Avalo Therapeutics (AVTX) investors?

Russell 2000 inclusion places Avalo among U.S. small-cap equities tracked by a leading benchmark. According to Avalo Therapeutics, Russell indexes are widely used by investment and institutional managers for index funds and as benchmarks for active strategies, potentially increasing investor attention.

How does the Russell 3000 index relate to Avalo Therapeutics (AVTX)?

Avalo Therapeutics will join the Russell 3000, which measures performance of the largest 3,000 U.S. public companies. According to Avalo Therapeutics, this index represents about 96% of the investable U.S. equity market, broadening the company’s market benchmarking universe.

What kind of company is Avalo Therapeutics (AVTX) joining the Russell indexes?

Avalo Therapeutics is a clinical-stage biotechnology company focused on developing therapeutics targeting the IL-1β pathway for immune-mediated inflammatory diseases. According to Avalo Therapeutics, this specialization underpins its growth profile as it joins the Russell 2000 and Russell 3000 indexes.