BetterLife Pharma Inc. develops BETR-001, a proprietary non-hallucinogenic derivative of LSD and neuroplastogen, for psychiatric and neurological disorders. News about BETRF commonly covers scientific updates on BETR-001’s mechanism of action and neuroplastogenic activity, intellectual property and regulatory-preparation disclosures, and disease areas such as traumatic brain injury, post-traumatic stress disorder, cluster headache, depression and anxiety.
Company updates also include strategic partnering and conference participation, development alternatives for its viral-infection therapeutic candidate, debt settlements and warrant exercises, board and advisory appointments, and public-company disclosure matters in Canada and the U.S. OTC market.
BetterLife Pharma (CSE: BETR / OTCQB: BETRF) has appointed Dr. Steven Sangha to its Board of Directors. Dr. Sangha brings 25 years of experience in investment banking, business development, and asset management, along with expertise in public company governance and compliance. He holds a Doctorate of Dental Surgery from the University of Western Ontario and a Bachelor of Pharmaceutical Science from UBC.
As the largest shareholder of BetterLife, Dr. Sangha expressed confidence in BETR-001, describing it as the best asset in its class for treating depression, anxiety, PTSD, and addiction. The company is focusing on developing non-hallucinogenic compounds for psychiatric and neurological disorders, with plans to advance BETR-001 to human clinical trials in the near future.
BetterLife Pharma (CSE: BETR / OTCQB: BETRF / FRA: NPAU), a biotech company developing BETR-001 (a non-hallucinogenic LSD derivative), has announced debt conversions. The company has issued 642,329 common shares and an equal number of share purchase warrants following the conversion of convertible debentures and accrued interest totaling $64,232.88.
The share purchase warrants can be exercised on a one-for-one basis at $0.10 per warrant, with expiration dates set for September 27, 2026, and October 29, 2026.
BetterLife Pharma (CSE: BETR, OTCQB: BETRF, FRA: NPAU), an emerging biotech company, announced that the USPTO has granted the BETR-001 composition of matter patent (US2023/0219955), expiring in 2042. BETR-001 is a non-hallucinogenic derivative of LSD. This new patent adds to BetterLife's existing intellectual property, which includes patents for the synthesis of 2-bromo-LSD (US9,868,732B2 and US10,377,752B2) issued in 2018 and 2019.
Dr. Ahmad Doroudian, CEO of BetterLife, stated that this patent is a significant milestone, ensuring the commercial potential of BETR-001, the R:R stereoisomer of 2-bromo-LSD. BetterLife is the first to demonstrate that the R:R stereoisomer is active at the neuroreceptors involved in treating various mental health disorders.
The company is actively pursuing additional claims such as method-of-use and has filed other patent applications covering BETR-001 and other forms of 2-bromo-LSD. BetterLife is confident in its strong intellectual property position and the commercial viability of BETR-001.
BetterLife Pharma (CSE: BETR / OTCQB: BETRF) announced a favorable outcome in legal claims filed against the company and its subsidiary, MedMelior. The case, initiated in early 2021 by a former MedMelior director seeking US$12.5 million in damages, has concluded with no obligations for BetterLife.
The resolution came through a series of New York state and federal court dismissals on grounds of forum non conveniens. The former director's subsequent federal appeal attempt lapsed in early November after unsuccessful settlement attempts, effectively ending the legal proceedings without any payments or penalties against the company.
BetterLife Pharma has announced favorable cardiac safety data for its drug candidate BETR-001, a non-hallucinogenic derivative of LSD. The company completed GLP in vitro studies showing minimal impact on the hERG channel, important for cardiac functioning. The results align with previous in vivo cardiac safety telemetry studies and complement findings on BETR-001's activity at the 5HT-2B receptor, where it acts as an antagonist rather than an agonist. This is significant as agonism at 5HT-2B receptor is associated with cardiac valvulopathy. These positive results bring the company closer to completing IND-enabling studies and initiating clinical trials.
BetterLife Pharma has announced favorable results from IND-enabling genotoxicity studies for its lead drug candidate BETR-001, a non-hallucinogenic LSD derivative. The studies showed that oral BETR-001, even at high doses, demonstrates no bone marrow toxicity or DNA/chromosome damage. The GLP studies included bacterial reverse mutation assay and micronucleus tests both in vitro and in vivo. These safety assessments are required by the FDA for clinical trial approval. Additionally, the company issued 200,000 common shares and warrants following a $20,000 debenture conversion.
BetterLife Pharma (CSE: BETR / OTCQB: BETRF) has announced a fully subscribed non-brokered private placement of $1,100,000. The offering consists of units priced at $0.15, each comprising one common share and one full warrant. Each warrant allows the purchase of one common share at $0.20 for up to two years post-closing. The company plans to use the proceeds to advance its lead compound BETR-001, a non-hallucinogenic LSD derivative, and for general working capital. BetterLife, an emerging biotech firm, focuses on developing non-hallucinogenic LSD-based therapeutics for mental disorders. The closing is pending regulatory approvals.
BetterLife Pharma (CSE: BETR / OTCQB: BETRF) has announced the publication of its patent for treating mental or mood disorders using 2-bromo-LSD (BETR-001), a non-hallucinogenic LSD derivative. The company highlights BETR-001's advantage over traditional psychedelics, as it maintains therapeutic benefits without hallucinogenic effects. This comes after the FDA's recent rejection of MDMA for PTSD treatment due to concerns about hallucinogenic drugs.
BetterLife aims for patient self-administration of BETR-001 at home for various psychiatric and neurological disorders. The company is completing IND-enabling studies and plans to start human clinical trials soon. Additionally, BetterLife has issued 4,983,699 common shares and warrants through the conversion of convertible debentures, with 2,250,000 shares and warrants issued to CEO Dr. Ahmad Doroudian.
BetterLife Pharma, a biotech company focused on mental disorder treatments, announced the closure of a non-brokered private placement. The offering, initially announced on June 13, 2024, involved the issuance of 1,750,000 units at $0.10 per unit, raising $175,000 in gross proceeds. Each unit includes one common share and one full warrant, with each warrant allowing the purchase of an additional common share at $0.13 within 24 months. These units will be subject to a four-month hold period under Canadian securities laws.
BetterLife Pharma announced that its researchers will present preclinical data on BETR-001 at the 2024 FENS conference in Vienna. BETR-001 is a non-hallucinogenic LSD derivative targeting mental health disorders. The study, conducted by Drs. Vern Lewis and Argel Aguilar-Valles from Carleton University, reveals that BETR-001 activates key signaling pathways linked to neuroplasticity and neurotransmission, which are critical in treating depression and anxiety. Additionally, BETR-001 shows potential in addressing neurodegeneration and addiction. CEO Dr. Ahmad Doroudian expressed optimism about these findings, indicating broad therapeutic applications for BETR-001.