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Biomea Fusion Announces Oral Presentation of Icovamenib at the 23rd World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease (WCIRDC)

Biomea Fusion (Nasdaq: BMEA) will deliver an oral presentation of Week 52 long-term follow up data for icovamenib at the 23rd World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease (WCIRDC) in Los Angeles on Dec 3-6, 2025.

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Biomea Fusion (Nasdaq: BMEA) will deliver an oral presentation of Week 52 long-term follow up data for icovamenib at the 23rd World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease (WCIRDC) in Los Angeles on Dec 3-6, 2025. The oral talk (Abstract #0062COVALENT-111) is titled "Durable Glycemic and C-Peptide Improvements with Icovamenib, a Menin Inhibitor Targeting β-Cell Restoration in Insulin-Deficient Type 2 Diabetes" and is scheduled for Dec 5, 2025, 6:15 pm–7:45 pm PST. Biomea noted it is one of six oral presentations at the meeting and said poster and presentation materials will be available on the company website.

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Argus Dec 2 session
-5.22% close to close Open Argus
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News Market Reaction – BMEA

On Dec 2, the first trading day after this news, BMEA closed 5.22% below the previous close.

Data tracked by StockTitan Argus for the Dec 2 session.

Key Figures

Week 52 follow-up: Week 52 Congress dates: December 3–6, 2025 Oral presentation count: 6 oral presentations +5 more
Week 52 follow-up
Week 52
Long-term icovamenib follow-up data in insulin-deficient type 2 diabetes
Congress dates
December 3–6, 2025
23rd WCIRDC meeting in Los Angeles
Oral presentation count
6 oral presentations
Icovamenib talk is one of six oral presentations at WCIRDC
Presentation window
6:15 pm–7:45 pm PST
Scheduled oral presentation time on December 5, 2025
Price change
14.93%
Pre-news 24h price change for BMEA
52-week range high
6.44
52-week high price before this news
52-week range low
0.8719
52-week low price before this news
Market cap
$108,883,604
Market capitalization prior to this announcement

Historical Context

5 past events · Latest: Dec 09
5 events
  1. Dec 09

    KOL presentation

    24h Move
    -0.7%

    KOL interview and WCIRDC presentation on menin inhibitors and icovamenib.

  2. Dec 05

    Clinical results

    24h Move
    +3.9%

    COVALENT-111 data showing durable glycemic and C-peptide improvements at week 52.

  3. Dec 01

    Conference presentation

    24h Move
    -7.3%

    Announcement of WCIRDC oral presentation for week 52 icovamenib follow-up data.

  4. Dec 01

    Equity inducement

    24h Move
    -7.3%

    Inducement stock option grant to a new employee under 2023 plan.

  5. Nov 24

    Investor conferences

    24h Move
    +2.9%

    Planned participation in early December investor healthcare conferences.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Key Terms

c-peptide, menin inhibitor, β-cell, type 2 diabetes
4 terms
c-peptide medical
"Durable Glycemic and C-Peptide Improvements with Icovamenib, a Menin Inhibitor"
C‑peptide is a short protein fragment released at the same time the pancreas produces insulin; because it lingers in the blood longer than insulin itself, clinicians measure C‑peptide levels as a clear sign of how much natural insulin a person still makes. For investors, C‑peptide matters because it’s used as a measurable outcome in diabetes drug and device trials, in diagnostic tests, and by regulators to judge treatment benefit — results that can affect clinical success, approvals, and market value.
menin inhibitor medical
"Icovamenib, a Menin Inhibitor Targeting β-Cell Restoration in Insulin-Deficient"
A menin inhibitor is a type of experimental drug that blocks the action of a protein called menin, which some cancers use to keep growing. Think of it as flipping off a switch that cancer cells rely on to survive; by doing so, these drugs can slow or stop tumor growth. Investors watch menin inhibitors because clinical trial results, regulatory approvals, and market demand determine whether they become valuable cancer treatments and potential revenue drivers.
β-cell medical
"a Menin Inhibitor Targeting β-Cell Restoration in Insulin-Deficient Type 2"
β-cells are the tiny hormone-producing cells in the pancreas that make and release insulin, the key chemical that tells the body to store or use sugar. Think of them as the body’s sugar thermostat and delivery service: when they work properly blood sugar stays steady, and when they fail diabetes can follow. Investors watch β-cell function because drugs, devices or therapies that protect, replace or improve these cells can change patient outcomes, regulatory approval chances and company value in the large diabetes market.
type 2 diabetes medical
"potential paradigm shift in the treatment of type 2 diabetes. Insulin-deficient"
Type 2 diabetes is a chronic condition where the body struggles to control blood sugar levels because it becomes less responsive to insulin, a hormone that helps regulate sugar in the blood. It matters to investors because it can lead to increased healthcare costs, affect workforce productivity, and influence the performance of companies in the healthcare and pharmaceutical sectors. Managing or preventing the condition has significant implications for public health and economic stability.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SAN CARLOS, Calif., Dec. 01, 2025 (GLOBE NEWSWIRE) -- Biomea Fusion, Inc. (“Biomea” or “Biomea Fusion” or “the Company”) (Nasdaq: BMEA), a clinical-stage diabetes and obesity company, today announced that it has been selected for an oral presentation of its long-term icovamenib follow up data at the 23rd World Congress on Insulin Resistance, Diabetes & Cardiovascular Disease (WCIRDC) taking place in Los Angeles, California on December 3-6, 2025. The Congress showcases cutting-edge developments from both emerging investigators and world-renowned leaders.

“We are delighted to present our Week 52 long-term follow up data at WCIRDC, a meeting renowned for showcasing exciting advances in diabetes and metabolic research,” said Mick Hitchcock, Ph.D., Interim CEO and Board Member of Biomea Fusion. “Being one of only six oral presentations this year speaks to the interest in icovamenib as a potential paradigm shift in the treatment of type 2 diabetes. Insulin-deficient diabetes remains an underserved population with limited therapeutic options, and icovamenib is potentially a novel treatment option for these patients.”

Oral Presentation Abstract #0062
COVALENT-111: Durable Glycemic and C-Peptide Improvements with Icovamenib, a Menin Inhibitor Targeting β-Cell Restoration in Insulin-Deficient Type 2 Diabetes
Presentation Time
Oral Presentation: December 5, 2025, from 6:15 pm – 7:45 pm PST

Please find a link here to our website where the poster and presentations will be available.

About Icovamenib
Icovamenib is an investigational, orally bioavailable, potent, and selective covalent inhibitor of menin. The proposed mechanism of action for icovamenib in diabetes is selective and partial inhibition of menin, a regulator of beta cell quantity and function, thereby enabling the proliferation, preservation, and reactivation of a patient’s own healthy, functional, insulin-producing beta cells. As the first non-chronic therapy for T2D, icovamenib could become an important addition to the diabetes treatment landscape once it has successfully completed its ongoing clinical studies.

About Biomea Fusion  
Biomea Fusion is a clinical-stage biopharmaceutical company advancing oral small molecule therapies, icovamenib and BMF-650, for diabetes and obesity. These programs target metabolic disorders, a global health challenge affecting nearly half of Americans and one-fifth of the world’s population. Biomea’s mission is to deliver transformative treatments that restore health for patients living with diabetes, obesity, and related conditions. We aim to cure.

Visit us at www.biomeafusion.com and follow us on LinkedIn, X and Facebook. 

Contact:
Meichiel Jennifer Weiss
Sr. Director of Investor Relations and Corporate Development
ir@biomeafusion.com


FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

When will Biomea Fusion (BMEA) present icovamenib data at WCIRDC 2025?

The oral presentation is scheduled for Dec 5, 2025, 6:15 pm–7:45 pm PST at WCIRDC in Los Angeles.

What data will Biomea Fusion (BMEA) present for icovamenib at WCIRDC?

Biomea will present Week 52 long-term follow up data showing durable glycemic and C-peptide improvements in insulin-deficient type 2 diabetes.

What is the WCIRDC abstract number for Biomea Fusion's icovamenib presentation (BMEA)?

The presentation is listed as Abstract #0062COVALENT-111.

Does Biomea Fusion (BMEA) expect to post materials from the WCIRDC presentation online?

Yes, the company indicated the poster and presentation materials will be available on the company website.

How notable is Biomea Fusion's (BMEA) selection for an oral presentation at WCIRDC 2025?

The company highlighted that it is one of six oral presentations at the meeting, indicating selective placement.

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