Bruker Light-Sheet Microscopes at Major Comprehensive Cancer Center

Bruker Corporation (Nasdaq: BRKR), a leading supplier of single-plane illumination microscopy (SPIM) technology for research on live cells and cleared biological samples, today announced that two Luxendo MuVi™ and LCS SPIM™ light-sheet microscopes have been installed by Memorial Sloan Kettering Cancer Center (MSK). The funding for the two light-sheet fluorescence microscopes was supported by Cycle for Survival (https://www.cycleforsurvival.org). The new SPIM microscopes will help researchers visualize the cellular and tissue hallmarks of cancer and translate those findings into better cancer treatment methods.

MuVi SPIM Multiview light-sheet microscope for live samples (Photo: Business Wire)

“By understanding how cells mobilize to build organs, researchers can glean insights into why some cells become cancerous and lead to organ destruction,” said Dr. Anna-Katerina Hadjantonakis, MSK Chair of the Developmental Biology Program. “Instruments such as these are useful for imaging across differing length scales — from subcellular to single cells to tissue-level processes — allowing researchers to study cellular dynamics and cellular motion, processes that enable cells to metastasize.”

“Light-sheet fluorescence microscopy has emerged as a uniquely powerful method for high-resolution, cleared-sample and dynamic biological imaging,” added Dr. Lars Hufna