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BioStem Technologies Announces Notice of Allowance for Four U.S. Design Patent Applications Covering Fenestrated Human Placental Allografts and One European Patent

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BioStem Technologies (OTCQB:BSEM) announced USPTO Notices of Allowance for four U.S. design patents covering fenestrated human placental allografts and a new European patent for sterile placental allografts and proprietary processing methods.

The patents expand a portfolio of over 70 patents supporting wound care, surgical, dental, cosmetic and regenerative applications.

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AI-generated analysis. Not financial advice.

Positive

  • Four new U.S. design patents allowed for fenestrated placental allografts
  • New European patent for sterile placental allografts and processing methods
  • Intellectual property portfolio expanded to more than 70 patents globally
  • Patented technologies target wound care, surgical, dental and cosmetic uses

Negative

  • None.

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BioStem Technologies Expands Global Placental Allograft Patent Portfolio

Pompano Beach, FL, May 20, 2026 (GLOBE NEWSWIRE) -- BioStem Technologies®, a leading regenerative medicine company focused on developing and commercializing placental-derived biologics, today announced that the United States Patent and Trademark Office (USPTO) has issued Notices of Allowance for four new divisional U.S. design patent applications related to its fenestrated human placental allograft technologies. The European Patent Office also issued BioStem a new patent covering sterile human placental allografts and proprietary manufacturing methods for growth factor-rich placental tissue allografts.

No. 30/010,024: FENESTRATED HUMAN PLACENTAL ALLOGRAFT
The patent is directed to fenestrated human placental allograft designs intended to improve conformability, fluid transfer, and handling characteristics during clinical use. The technology supports applications in wound care and surgical environments where enhanced drainage, flexibility, and tissue integration may help optimize placement and healing outcomes.

No. 30/010,026: FENESTRATED HUMAN PLACENTAL ALLOGRAFT
The patent is directed to fenestrated human placental allograft designs that facilitate fluid management. The design supports use in wound care and surgical settings where effective drainage is important.

No. 30/010,032: FENESTRATED HUMAN PLACENTAL ALLOGRAFT
The patent is directed to fenestrated allograft designs that preserve the structural integrity of amniotic and chorion tissues while supporting moisture management in complex wound environments.

No. 30/010,034: FENESTRATED HUMAN PLACENTAL ALLOGRAFT
The patent is directed to fenestrated allograft designs that enable controlled fluid passage that supports wound drainage and overall wound management across a range of applications.

Additionally, the European Patent Office issued BioStem a new patent covering sterile human placental allografts and proprietary methods of manufacturing growth factor-rich placental tissue allografts.

EP4442316A2: STERILE HUMAN PLACENTAL ALLOGRAFTS AND METHODS OF MAKING THEREOF
The patent is directed to sterile human placental allografts and proprietary processing methods designed to preserve the natural structural integrity and endogenous growth factors of placental tissue. The technology utilizes gentle cleaning, low-temperature dehydration, and low-dose e-beam sterilization techniques to create growth factor-rich allografts for wound healing, dental, cosmetic and surgical applications, while supporting improved tissue regeneration and reduced immunogenic response.

“This milestone reflects our continued focus on protecting the innovation behind our advanced perinatal tissue allograft technologies,” Jason Matuszewski, Chief Executive Officer of BioStem Technologies, said. “Our growing intellectual property portfolio supports our mission to deliver leading-edge solutions to clinicians and their patients.  These proprietary innovations continue to enhance our ability to differentiate BioStem’s product offering from the competition and drive adoption by clinicians.”

These patents represent continued momentum in BioStem's global intellectual property strategy, further strengthening a portfolio of more than 70 patents while advancing the development of next-generation products.

BioStem’s proprietary processing technologies are designed to optimize preservation of the innate structural and biological characteristics of placental tissues, supporting their use in a variety of clinical applications, including wound care and surgical procedures.

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Investor Relations:

Philip Trip Taylor, Gilmartin 

Group E-Mail: ir@biostemtech.com 

 

Public Relations:

Jennifer Horton, Relevance

jennifer@relevance.com

Press Inquiries

pr@biostemtech.com
954-380-8342
https://biostemtechnologies.com/


FAQ

What patents did BioStem Technologies (BSEM) announce on May 20, 2026?

BioStem Technologies announced four allowed U.S. design patents and one new European patent. According to BioStem, these patents cover fenestrated human placental allografts and sterile placental allografts with proprietary processing methods that preserve structural integrity and endogenous growth factors for clinical applications.

How do BioStem Technologies' new fenestrated placental allograft patents benefit clinical use?

The new patents describe fenestrated allograft designs aimed at improving fluid management and handling. According to BioStem, they support wound care and surgical settings by enhancing drainage, conformability, moisture management, and tissue integration, which may help optimize placement and overall wound management across various complex wound environments.

What does the new European patent EP4442316A2 cover for BioStem Technologies (BSEM)?

European patent EP4442316A2 covers sterile human placental allografts and methods of making them. According to BioStem, the methods use gentle cleaning, low-temperature dehydration, and low-dose e-beam sterilization to preserve natural tissue structure and growth factors for wound healing, dental, cosmetic, and surgical applications.

How large is BioStem Technologies' patent portfolio after the latest placental allograft patents?

BioStem reports that these patents further strengthen a portfolio of more than 70 patents. According to BioStem, the expanded intellectual property supports its global strategy and helps differentiate its perinatal tissue allograft products, potentially aiding clinician adoption in wound care and surgical markets.

What clinical applications are targeted by BioStem Technologies' newly protected placental allograft technologies?

The patented technologies target multiple clinical applications, including wound healing, dental, cosmetic, and surgical procedures. According to BioStem, their processing aims to optimize preservation of placental tissue’s structural and biological characteristics, supporting tissue regeneration, improved handling in surgery, and potentially reduced immunogenic response.

Why is BioStem Technologies expanding its fenestrated placental allograft IP portfolio?

BioStem is expanding this IP to protect innovation and support product differentiation. According to BioStem, the growing portfolio of advanced perinatal tissue allograft patents underpins its mission to deliver leading-edge regenerative solutions and helps drive adoption of its placental-derived biologics by clinicians and patients.