Welcome to our dedicated page for Candel Therapeutics news (Ticker: CADL), a resource for investors and traders seeking the latest updates and insights on Candel Therapeutics stock.
Candel Therapeutics, Inc. (NASDAQ: CADL) is a clinical-stage biopharmaceutical company pioneering viral immunotherapies for solid tumor treatment. This page serves as the definitive source for official updates on the company's innovative adenovirus and herpes simplex virus (HSV) platform developments.
Investors and researchers will find timely updates on clinical trial progress, regulatory milestones, and strategic partnerships. Our curated collection includes press releases detailing therapy advancements, peer-reviewed research collaborations, and manufacturing updates relevant to CADL's immuno-oncology pipeline.
Key content categories include phase trial results, FDA communications, intellectual property developments, and executive leadership announcements. All materials are sourced directly from company filings and verified channels to ensure accuracy.
Bookmark this page for streamlined access to Candel Therapeutics' latest developments in cancer immunotherapy. Check regularly for updates on their gmci™ and rqnestin34.5 platforms as they progress through clinical evaluation.
Candel Therapeutics (Nasdaq: CADL) has appointed Dr. Elizabeth M. Jaffee to its Research Advisory Board. Dr. Jaffee, an internationally recognized expert in cancer immunology and pancreatic cancer, currently serves as the Dana and Albert Broccoli Professor of Oncology and Deputy Director at Johns Hopkins' Sidney Kimmel Comprehensive Cancer Center.
The appointment is particularly significant given Candel's focus on borderline resectable pancreatic cancer and follows their recent positive survival data for the CAN-2409 program. Dr. Jaffee's expertise will contribute to designing late-stage clinical trials for this program.
Dr. Jaffee's credentials include serving as past President of the American Association for Cancer Research, co-chair of the Biden Moonshot Blue Ribbon Panel, and Chief Medical Advisor to the Lustgarten Foundation for Pancreatic Cancer Research. She is also a member of the National Academy of Medicine and previously chaired President Biden's Cancer Panel.
Candel Therapeutics (NASDAQ: CADL) reported its Q4 and full year 2024 financial results, highlighting significant clinical progress across its pipeline. The company announced positive phase 3 data for CAN-2409 in prostate cancer, showing a 30% reduction in cancer recurrence risk and 80.4% pathological complete responses. In pancreatic cancer, CAN-2409 demonstrated notable survival improvements, with median overall survival of 31.4 months versus 12.5 months in the control group.
Financial highlights include:
- Q4 2024 R&D expenses: $4.8M (vs $7.3M in Q4 2023)
- Q4 2024 net loss: $14.1M (vs $11.1M in Q4 2023)
- Cash position: $102.7M as of December 31, 2024
- Runway extended into Q1 2027
Key upcoming milestones include final overall survival data for CAN-2409 in NSCLC (Q1 2025) and biomarker data for CAN-3110 in high-grade glioma (Q4 2025). The company plans to submit a BLA for CAN-2409 in prostate cancer in Q4 2026.
Candel Therapeutics (NASDAQ: CADL) has announced positive final survival data from its Phase 2 clinical trial of CAN-2409 in non-metastatic pancreatic cancer. The randomized controlled study showed a remarkable improvement in estimated median overall survival - 31.4 months in the CAN-2409 treatment group versus only 12.5 months in the control group for patients with borderline resectable pancreatic ductal adenocarcinoma (PDAC).
Notably, three of seven patients treated with CAN-2409 were still alive at 66.0, 63.6, and 35.8 months after enrollment, with survival from diagnosis reaching 73.5, 68.8, and 41.3 months respectively. This survival duration significantly exceeds expectations for standard pancreatic cancer treatment.
CAN-2409, a first-in-class multimodal immunotherapy designed for in situ vaccination against the patient's tumor, demonstrated a favorable safety profile and has previously received both Fast Track Designation and Orphan Drug Designation from the FDA for PDAC treatment. Based on these promising results, Candel plans to prepare for a larger, late-stage randomized controlled clinical trial of CAN-2409 in PDAC.
Candel Therapeutics (NASDAQ: CADL) provided a corporate update highlighting pipeline progress and 2025 milestones. The company reported positive phase 3 data for CAN-2409 in prostate cancer, showing a 30% reduction in cancer recurrence risk and 80.4% pathological complete responses. Updated survival data for CAN-2409 in pancreatic cancer showed median overall survival of 28.8 months versus 12.5 months in the control group.
Key upcoming milestones include updated overall survival data for CAN-2409 in pancreatic cancer and non-small cell lung cancer (Q1 2025), overall survival data for CAN-3110 in recurrent high-grade glioma (Q4 2025), and BLA submission for CAN-2409 in prostate cancer (Q4 2026). The company's cash position of $102.9M as of December 31, 2024, is expected to fund operations into Q1 2027.
Candel Therapeutics (NASDAQ: CADL) has successfully closed its public offering, selling 12,000,001 shares of common stock at $6.00 per share and 3,333,333 pre-funded warrants at $5.99 per warrant. The offering includes 2,000,000 additional shares from the full exercise of the underwriters' option. The company raised approximately $92 million in gross proceeds before deducting expenses.
The funds will be used to advance product development, including the preparation of a Biologics License Application for CAN-2409 in prostate cancer, and for general corporate purposes. The offering was managed by Citigroup, BofA Securities, and Canaccord Genuity as joint bookrunners, with H.C. Wainwright & Co. as lead manager.
Candel Therapeutics (CADL) has announced the pricing of a public offering, consisting of 10,000,001 shares of common stock at $6.00 per share and pre-funded warrants to purchase 3,333,333 shares at $5.99 per warrant. The offering is expected to generate approximately $80 million in gross proceeds and close around December 16, 2024. The company has granted underwriters a 30-day option to purchase up to 2,000,000 additional shares. Proceeds will fund product development, including preparation for a Biologics License Application for CAN-2409 in prostate cancer, and general corporate purposes. The offering is led by joint bookrunning managers Citigroup, BofA Securities, and Canaccord Genuity.
Candel Therapeutics (NASDAQ: CADL) has announced an underwritten public offering of $80 million of its common stock and pre-funded warrants. The company will grant underwriters a 30-day option to purchase up to an additional $12 million of common stock. The proceeds will be used to continue product development, including preparing a Biologics License Application for CAN-2409 in prostate cancer, and for general corporate purposes. Citigroup, BofA Securities, and Canaccord Genuity are acting as joint bookrunning managers, with H.C. Wainwright & Co. as lead manager. The offering will be made through a shelf registration statement previously filed with the SEC.
Candel Therapeutics (CADL) announced positive Phase 3 clinical trial results for CAN-2409 viral immunotherapy in localized prostate cancer patients. The trial met its primary endpoint, demonstrating statistically significant improvement in disease-free survival when combined with radiation therapy. Key results include:
- 14.5% relative improvement in disease-free survival at 54 months
- Highly significant effect on prostate cancer-free survival (p=0.0046)
- 80.4% pathological complete responses vs 63.6% in control group
- Safety profile consistent with previous studies
The trial enrolled 745 patients and was conducted under FDA Special Protocol Assessment. The addressable market for CAN-2409 in localized prostate cancer is estimated at over $10 billion in the U.S. alone. The company plans to initiate FDA discussions regarding regulatory approval.
Candel Therapeutics (CADL) reported Q3 2024 financial results with a net loss of $10.6 million compared to $8.4 million in Q3 2023. Research and development expenses decreased to $5.4 million from $5.8 million year-over-year, while general and administrative expenses increased to $3.3 million from $3.0 million. The company's cash position stands at $16.6 million, expected to fund operations through Q1 2025.
The company remains on track for two key clinical trial readouts in Q4 2024: topline disease-free survival data from the phase 3 trial of CAN-2409 in intermediate/high-risk prostate cancer and topline progression-free survival data from the phase 2b trial in low/intermediate risk prostate cancer. Additionally, promising clinical data was reported for CAN-3110 in recurrent high-grade glioma, with 3 out of 6 patients surviving over one year.
Candel Therapeutics (Nasdaq: CADL), a clinical stage biopharmaceutical company developing biological immunotherapies for cancer treatment, has announced its participation in the Jefferies London Healthcare Conference 2024.
The company's President and CEO, Paul Peter Tak, will deliver a presentation on Wednesday, November 20, 2024, from 9:30-9:55AM GMT / 4:30-4:55AM EST. The presentation will be accessible via webcast, with a replay available for up to 90 days on the company's website under the Investors section.
FAQ
What is the current stock price of Candel Therapeutics (CADL)?
What is the market cap of Candel Therapeutics (CADL)?
