Welcome to our dedicated page for Can-Fite BioPharma Ltd. news (Ticker: CANF), a resource for investors and traders seeking the latest updates and insights on Can-Fite BioPharma Ltd. stock.
Can-Fite BioPharma Ltd. (CANF) is a clinical-stage biotechnology company whose news flow centers on the development of orally administered small-molecule drugs targeting the A3 adenosine receptor. On this page, readers can follow company announcements on clinical trial progress, regulatory designations, patent developments, financing events, and corporate actions related to its oncology, liver disease, inflammatory, and sexual dysfunction programs.
Recent news has highlighted pivotal and mid-stage clinical studies, including a Phase III trial of Namodenoson in advanced hepatocellular carcinoma, a Phase IIb trial in MASH, and a Phase IIa study in pancreatic cancer. The company has also reported compassionate use cases in advanced liver disease and cirrhosis, as well as long-term survival outcomes in liver cancer patients treated with Namodenoson. For Piclidenoson, updates include Phase III psoriasis development and protocol preparation for rare diseases such as Lowe Syndrome, along with preclinical findings in vascular dementia models.
News items also cover CF602, an A3AR allosteric modulator in development for erectile dysfunction, including patent allowances and grants in markets such as Brazil, the United States, and Europe. Can-Fite regularly reports on its intellectual property strategy, out-licensing and distribution agreements for human and veterinary indications, participation in industry conferences, and capital markets activities such as public offerings, warrant amendments, and share structure changes like reverse splits and ADS ratio adjustments.
Investors and observers can use this CANF news feed to monitor key milestones that may affect the company’s clinical pipeline, regulatory interactions, partnering discussions, and financial position over time.
Can-Fite BioPharma Ltd. (NYSE American: CANF) reported financial results for the quarter ended September 30, 2021, highlighting key developments in its clinical pipeline. The company completed patient enrollment in its Phase III Comfort™ psoriasis study, with results expected in Q1 2022. Notably, Can-Fite discontinued its Phase II COVID-19 trial to focus on its primary indications. The financial results show revenues of $0.65 million, a slight increase from $0.61 million, while net loss decreased to $8.49 million, down from $10.81 million in 2020. The company’s cash and equivalents reached $13.3 million, bolstered by fundraising activities.
Can-Fite BioPharma (NYSE American: CANF) announced that CEO Dr. Pnina Fishman will present at the 5th Annual NASH Summit from November 29 to December 2, 2021. Dr. Fishman's presentation, scheduled for December 1 at 1:30 PM ET, will discuss the Phase 2a study of Namodenoson, an A3AR Agonist, in treating Non-alcoholic Fatty Liver Disease and Non-alcoholic Steatohepatitis. The 5th Annual NASH Summit gathers experts to enhance understanding of NASH clinical science. Namodenoson recently completed a successful Phase IIa trial, meeting its primary endpoint.
Can-Fite BioPharma announced that its veterinary partner, Vetbiolix, has initiated a safety and efficacy study of Piclidenoson for treating canine osteoarthritis, targeting a market expected to reach $3 billion by 2024. Safety results are anticipated in Q1 2022, with efficacy data expected in Q4 2022. Piclidenoson has shown a favorable safety profile in over 1,500 human patients. The study aims to provide a safer alternative to existing treatments, with Vetbiolix responsible for development costs and potential royalties upon regulatory approval.
Can-Fite BioPharma (NYSE American: CANF) announced that CEO Dr. Pnina Fishman will present at the H.C. Wainwright 7th Annual Israel Conference on November 15, 2021, at 12:30 PM ET. The presentation will emphasize Can-Fite's advanced-stage pipeline, including a Phase III study in psoriasis with results expected in Q1 2022. Upcoming studies include a Phase II study in NASH and a pivotal Phase III trial in liver cancer. Can-Fite is focused on developing proprietary drugs for inflammatory diseases, cancer, and liver conditions, including the candidates Piclidenoson and Namodenoson.
Can-Fite BioPharma (NYSE American: CANF) announced that CEO Dr. Pnina Fishman will present research on the CBD Rich T3/C15 cannabis fraction at the American Association for the Study of Liver Diseases (AASLD) The Liver Meeting from November 12-15, 2021. The study indicates that this cannabis fraction inhibits the growth of HEP-3b hepatocellular carcinoma cells via the A3 Adenosine Receptor. This inhibitory activity suggests potential therapeutic applications in liver cancer treatment.
Can-Fite BioPharma (NYSE: CANF) announced the granting of a patent for its NASH drug candidate, Namodenoson, in Hong Kong and Mexico, with a notice of allowance in Japan. This patent enhances Can-Fite's intellectual property in treating ectopic fat accumulation related to NAFLD and NASH, projected to reach a $35 billion market by 2025. Namodenoson has successfully completed a Phase IIa study and is currently in Phase IIb trials. The company has secured about $20 million in non-dilutive payments for Namodenoson across multiple regions.
Can-Fite BioPharma (NYSE American: CANF) announced that CEO Dr. Pnina Fishman will present at the 5th Annual Antifibrotic Drug Development Summit on November 3, 2021. Her presentation will highlight innovative strategies for promoting tissue regeneration, focusing on clinical trial data for Namodenoson, which showed a dose-dependent reduction in liver fat and fibrosis in a Phase IIa study. The Phase IIb study is currently approved and underway, while Can-Fite continues to advance its clinical pipeline in cancer and liver diseases.
Can-Fite BioPharma Ltd (NYSE: CANF) announced the publication of a study on Namodenoson for treating non-alcoholic fatty liver disease (NASH) in the journal Alimentary Pharmacology & Therapeutics. The Phase IIa trial met its endpoints, showcasing significant anti-steatotic, anti-fibrotic, and anti-inflammatory effects. A Phase IIb trial is set to enroll patients in Q4 2021. The market for NASH treatments is projected to reach $35-40 billion by 2025. With no current U.S. approved drugs for NASH, the potential for Namodenoson is substantial.
Can-Fite BioPharma Ltd. (NYSE American: CANF) announced that CEO Dr. Pnina Fishman will present at the NASH Investor Conference on October 12, 2021, at 9:30 am ET. The conference will include a panel of experts discussing NASH, a liver disease with no approved treatments in the U.S. Can-Fite's drug candidate, Namodenoson, is set to enter a Phase IIb trial for NASH in Q4 2021, following successful Phase IIa results. The NASH market is projected to reach $35-40 billion by 2025.
Can-Fite BioPharma Ltd. (NYSE American: CANF) will have CEO Dr. Pnina Fishman present at the Benzinga Healthcare Small Cap Conference on September 29, 2021.
The presentation will include a panel discussion on medical cannabis and insights into Can-Fite’s drug development efforts, including ongoing trials for Piclidenoson and Namodenoson targeting psoriasis and liver cancer. With FDA designations for Namodenoson, Can-Fite aims to capture significant market opportunities in the pharmaceutical industry.