Welcome to our dedicated page for Crescent Biopharma news (Ticker: CBIO), a resource for investors and traders seeking the latest updates and insights on Crescent Biopharma stock.
Crescent Biopharma reports news about its clinical-stage oncology pipeline, including CR-001, a PD-1 x VEGF bispecific antibody, and antibody-drug conjugate programs such as CR-002 and CR-003. Company updates commonly cover clinical trial activity in solid tumors, pipeline combinations, collaboration activity, financial results, and business highlights.
Recurring corporate announcements also include investor conference presentations and equity inducement awards under the company’s employment inducement incentive plan. These updates reflect Crescent’s status as a Nasdaq-listed biotechnology issuer focused on cancer therapeutics.
Catalyst Biosciences disclosed promising preclinical data for its gene therapy candidate CB 2679d-GT in hemophilia B, published in Blood. The study showed that CB 2679d-GT outperformed the R338L-Padua variant, demonstrating enhanced efficacy with significantly reduced bleeding times. Conducted by Vrije Universiteit Brussel, the findings suggest CB 2679d-GT may allow for lower vector doses in future human trials. This advancement supports further clinical development of CB 2679d-GT as a leading option for hemophilia B treatment.
Catalyst Biosciences (NASDAQ: CBIO) has announced the extension of its patent protection for the lead candidate CB 2782-PEG until at least 2038, following the issuance of U.S. Patent Number 10,954,501 B2. This patent secures intellectual property related to modified proteases that target complement factor 3 (C3), supporting the company’s ongoing work in treating dry age-related macular degeneration (AMD). Catalyst's CEO emphasized the importance of a robust patent estate for future development, aiming to enhance shareholder value through various protease medicine assets.
Catalyst Biosciences (NASDAQ: CBIO) will present a corporate overview at the 20th Annual Needham Virtual Healthcare Conference on April 15, 2021, at 3:00 PM ET. Interested parties can access a live webcast and an archived version available for 90 days. The company focuses on developing treatments for rare disorders, featuring their protease engineering platform, which includes MarzAA, a next-generation coagulation Factor VIIa for episodic bleeding. Additionally, they are collaborating with Biogen on a pre-clinical C3-degrader program for dry age-related macular degeneration.
Catalyst Biosciences (NASDAQ: CBIO) reported fourth quarter and full-year 2020 results on March 4, 2021. The company achieved Fast Track designation for MarzAA, a treatment for hemophilia. Catalyst raised approximately $49.3 million in net proceeds from a financing round, enhancing its total capital to over $130 million. The firm reported a net loss of $18.9 million for Q4 and $56.2 million for the full year. R&D expenses increased to $53 million annually, driven by personnel and research costs. Cash and investments stood at $81.9 million as of year-end 2020.
Catalyst Biosciences, Inc. (NASDAQ: CBIO) will participate in a fireside chat at the Raymond James 42nd Annual Institutional Investors Conference on March 3, 2021, at 2:10 pm ET. Investors can access a live webcast of the event here. Catalyst focuses on rare disorders related to the complement and coagulation systems, with late-stage programs like MarzAA for bleeding disorders.
Catalyst Biosciences (NASDAQ:CBIO) announced the closing of an additional 485,000 shares at $5.75 each, netting approximately $2.8 million. The company aims to use these funds for general corporate needs, including research and development in hemophilia and complement programs, capital expenditures, and working capital.
Piper Sandler & Co. and Raymond James & Associates acted as bookrunners for the offering. This transaction follows an effective registration statement filed with the SEC in February 2019.
Catalyst Biosciences (NASDAQ: CBIO) announced positive pre-clinical findings for Marzeptacog alfa (activated) – MarzAA, at the EAHAD Congress on February 3, 2021. The next-gen engineered coagulation Factor VII demonstrated significant efficacy in controlling spontaneous bleeding in Hemophilia A rats and dogs. Most subjects required only a single subcutaneous dose for effective management. MarzAA is advancing to a Phase 3 trial for hemophilia patients. Catalyst aims to address unmet needs in bleeding disorders with its innovative therapies.
Catalyst Biosciences (NASDAQ:CBIO) has successfully closed an underwritten public offering of 8,700,000 shares at $5.75 each, raising approximately $50 million in gross proceeds. The funds will support general corporate purposes, including R&D in hemophilia and complement programs like MarzAA and CB 4332. The offering utilized an effective shelf registration with the SEC, showcasing Catalyst's ongoing commitment to address rare disorders. Piper Sandler & Co. served as the lead bookrunner for this offering.
Catalyst Biosciences, Inc. (NASDAQ:CBIO) announced a public offering of 8,700,000 shares at $5.75 each, with expected gross proceeds of $50 million. The offering includes a 30-day option for underwriters to purchase an additional 1,305,000 shares. Proceeds will support general corporate purposes, focusing on hemophilia and complement programs, including MarzAA and CB 4332. The offering is anticipated to close on January 29, 2021. Piper Sandler & Co. is the lead bookrunner.
Catalyst Biosciences (NASDAQ: CBIO) has announced an underwritten public offering of its common stock, with market conditions influencing the amount and terms. The company may grant underwriters a 30-day option to purchase an additional 15% of shares. Proceeds will support general corporate purposes, including research and development in hemophilia and complement programs, capital expenditures, and operational costs. The offering will use a previously filed effective registration statement. Piper Sandler & Co. and Raymond James & Associates are involved as bookrunners.