C4 Therapeutics, Inc. reports developments tied to its clinical-stage targeted protein degradation business, including oncology programs designed with its TORPEDO® platform. Recurring company updates cover cemsidomide, an oral IKZF1/3 degrader being studied in relapsed/refractory multiple myeloma, as well as broader degrader-medicine research intended to address disease-causing proteins.
Company news also includes collaboration activity, such as its Roche agreement for degrader-antibody conjugates, along with clinical disclosures, operating and financial results, conference participation, equity inducement grants, and other governance matters under Nasdaq rules.
C4 Therapeutics, Inc. (Nasdaq: CCCC) announced that a late-breaking abstract featuring preclinical data for its protein degrader CFT7455 has been selected for presentation at the AACR 2021 Annual Meeting, scheduled for April 10-15, 2021. CFT7455 targets IKZF1/3 to treat hematologic malignancies and has demonstrated potent tumor regression in IMiD-resistant multiple myeloma models. This signifies a key milestone for C4T in advancing innovative cancer treatments through targeted protein degradation, potentially overcoming limitations of traditional therapies.
C4 Therapeutics, Inc. (Nasdaq: CCCC), a biopharmaceutical company innovating small-molecule medicines that degrade disease-causing proteins, has announced participation in two investor conferences in March 2021. They will present at the Cowen 41st Annual Health Care Conference on March 3 at 11:40 a.m. ET and the Guggenheim Targeted Protein Degradation Day on March 16 at 10:30 a.m. ET. Webcasts can be accessed on their website and will be available for two weeks post-event. C4T focuses on targeted protein degradation to treat cancer, neurodegenerative diseases, and more.
C4 Therapeutics (Nasdaq: CCCC) announced its participation in the BMO BioPharma Spotlight Series on February 18, 2021, at 10:30 a.m. ET. The panel discussion, titled “Ligating” Competitors for Collaboration in the Protein Degradation Space, will focus on next-generation technologies in protein degradation. A recording will be available for replay four hours post-event on the company’s website, archived for at least two weeks. C4T specializes in small-molecule medicines targeting disease-causing proteins, offering improved treatment options for cancer and neurodegenerative diseases.
C4 Therapeutics (Nasdaq: CCCC) announced FDA clearance of its IND application for CFT7455, an innovative oral MonoDAC targeting IKZF1/3, aimed at treating hematologic malignancies like multiple myeloma and non-Hodgkin lymphomas. This milestone allows the company to commence a Phase 1/2 clinical trial in the first half of 2021, following a positive 30-day safety review. The trial will evaluate CFT7455's safety, tolerability, and efficacy as a single agent and in combination therapies.
C4 Therapeutics, a biopharmaceutical company, announced its participation in the 39th Annual J.P. Morgan Healthcare Conference on January 14, 2021, at 2:50 p.m. ET. This event will showcase C4T's pioneering approach to developing small-molecule medicines that target and degrade disease-causing proteins. A live webcast of the presentation will be available in the Investors section of their website, with a replay accessible for two weeks post-event. C4T focuses on cancer and neurodegenerative disease treatments, emphasizing advantages like higher potency and reduced side effects.
C4 Therapeutics (Nasdaq: CCCC) has submitted an Investigational New Drug (IND) application for its lead candidate CFT7455, aimed at treating hematologic malignancies, with FDA review underway. A Phase 1/2 trial is anticipated to begin in the first half of 2021. Additionally, C4T plans to submit an IND for CFT8634 in the second half of 2021 and advance BRAF and RET programs into IND-enabling studies later this year. The company expects its current cash reserves of approximately $370 million to support operations through the end of 2023.
C4 Therapeutics, Inc. (Nasdaq: CCCC) has been added to the Russell 2000® and Russell 3000® Indexes, effective December 21, 2020. This inclusion follows their IPO just two months earlier and aims to enhance the company's visibility to investors. The Russell 2000® Index tracks small-cap stocks and serves as a benchmark for investment strategies, with around $9 trillion in assets connected to it. C4 Therapeutics focuses on developing small-molecule drugs to degrade disease-causing proteins, targeting cancer and neurodegenerative diseases.
C4 Therapeutics (Nasdaq: CCCC), a biopharmaceutical pioneer in targeted protein degradation, will present at the Evercore ISI 3rd Annual HealthCONx on December 3, 2020, at 8:25 a.m. ET.
Investors can access a live webcast of the presentation on the company’s website, with a replay available for two weeks post-event. C4T focuses on therapeutics that selectively destroy disease-causing proteins, offering potential advantages over traditional treatments, particularly in cancer and neurodegenerative diseases.
C4 Therapeutics (Nasdaq: CCCC), a biopharmaceutical innovator, will present at the Jefferies Virtual London Healthcare Conference on November 19, 2020, at 8:30 a.m. ET. C4T specializes in a unique class of small-molecule drugs aimed at selectively degrading disease-causing proteins, targeting conditions like cancer and neurodegenerative diseases. A live webcast of the presentation will be available on their website, with a replay archived for two weeks. This targeted protein degradation approach offers potential advantages over traditional therapies, including reduced drug resistance and fewer side effects.
C4 Therapeutics, Inc. (Nasdaq: CCCC) has reinforced its leadership team with key appointments, including Andrew Hirsch as CEO. The company successfully completed an upsized IPO in October 2020, raising $209.8 million, extending its cash runway into the second half of 2023. For Q3 2020, C4T reported revenues of $8.4 million, up from $5.4 million in Q3 2019, driven by collaboration agreements. However, R&D expenses surged to $23.9 million, resulting in a net loss of $21.8 million. The company anticipates an IND submission for its lead candidate, CFT7455, by the end of 2020.