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Compugen to Present New Clinical Data Showing Preliminary Anti-Tumor Activity of COM701 Triple Combination in Recurrent MSS-Metastatic Endometrial Cancer at ASCO 2023

Compugen Ltd. (Nasdaq: CGEN) has announced that it will present new clinical data regarding its candidate COM701 during the upcoming American Society of Clinical Oncology (ASCO) annual meeting from June 2-6, 2023, in Chicago.

(Moderate)

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Rhea-AI Summary

Compugen Ltd. (Nasdaq: CGEN) has announced that it will present new clinical data regarding its candidate COM701 during the upcoming American Society of Clinical Oncology (ASCO) annual meeting from June 2-6, 2023, in Chicago. The data will focus on the triple combination therapy of COM701, BMS-986207 (anti-TIGIT), and nivolumab in patients with metastatic endometrial cancer. The presentation titled Preliminary antitumor activity of the combination of COM701 + BMS-986207 + nivolumab is scheduled for June 5, 2023. This research highlights Compugen's commitment to innovative cancer immunotherapy methods.Company Background: Compugen is advancing several therapeutic programs, including COM902 and the partnered program rilvegostomig, with a focus on addressing immune resistance in cancer treatments.

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Positive

  • Presentation of new clinical data at ASCO 2023.
  • Focus on innovative triple combination therapy for metastatic endometrial cancer.
  • Strong pipeline with programs targeting immune resistance mechanisms.

Negative

  • None.
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HOLON, Israel, April 27, 2023 /PRNewswire/ -- Compugen Ltd. (Nasdaq: CGEN) (TASE:CGEN), a clinical-stage cancer immunotherapy company and a pioneer in computational target discovery, today announced that it will present new clinical data on COM701 in triple combination with BMS-986207 (anti-TIGIT) and nivolumab in metastatic endometrial cancer at the American Society of Clinical Oncology (ASCO) annual meeting on June 2-6, 2023, in Chicago, Illinois.

Poster Presentation Details:

Title: Preliminary antitumor activity of the combination of COM701 + BMS-986207 + nivolumab in patients with recurrent, metastatic MSS endometrial cancer
Abstract Number: 5595
Session Title: Gynecologic Cancer
Lead Author: Rasco, D, MD
Date: Monday, June 5, 2023

About Compugen
Compugen is a clinical-stage therapeutic discovery and development company utilizing its broadly applicable predictive computational discovery capabilities to identify new drug targets and biological pathways for developing cancer immunotherapies. Compugen has developed two proprietary product candidates: COM701, a potential first-in-class anti-PVRIG antibody and COM902, a potential best-in-class antibody targeting TIGIT for the treatment of solid tumors. Compugen also has a clinical stage partnered program, rilvegostomig (previously AZD2936), a PD-1/TIGIT bi-specific derived from COM902, that is in Phase 2 development by AstraZeneca through a license agreement for the development of bi-specific and multi-specific antibodies. In addition, the Company's therapeutic pipeline of early-stage immuno-oncology programs consists of programs aiming to address various mechanisms of immune resistance. The most advanced program, COM503 is advancing in IND enabling studies. COM503 is a potential first-in-class, high affinity antibody which blocks the interaction between IL-18 binding protein and IL-18, thereby freeing natural IL-18 to inhibit cancer growth in the tumor microenvironment. Compugen is headquartered in Israel, with offices in San Francisco, CA. Compugen's shares are listed on Nasdaq and the Tel Aviv Stock Exchange under the ticker symbol CGEN.

Company contact:
Yvonne Naughton, Ph.D.
Head of Investor Relations and Corporate Communications
Email: ir@cgen.com  
Tel: +1 (628) 241-0071 

 

Cision View original content:https://www.prnewswire.com/news-releases/compugen-to-present-new-clinical-data-showing-preliminary-anti-tumor-activity-of-com701-triple-combination-in-recurrent-mss-metastatic-endometrial-cancer-at-asco-2023-301809359.html

SOURCE Compugen Ltd.

FAQ

AI-generated questions and answers. How Rhea-AI works. Not financial advice.

What is the focus of Compugen's presentation at ASCO 2023?

Compugen's presentation will focus on the clinical data for COM701 in combination with BMS-986207 and nivolumab for metastatic endometrial cancer.

When is Compugen presenting at ASCO 2023?

Compugen is set to present on June 5, 2023, at the ASCO annual meeting.

What is the significance of the COM701 triple combination?

The COM701 triple combination aims to demonstrate preliminary antitumor activity in patients with recurrent metastatic endometrial cancer.

What are Compugen's therapy targets?

Compugen targets various mechanisms of immune resistance with its therapeutic programs, including COM701, COM902, and rilvegostomig.

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