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Cognition Therapeutics, Inc. develops clinical-stage drug candidates for neurodegenerative disorders, with news centered on zervimesine (CT1812), an investigational oral small molecule designed to protect neuronal synapses from toxic protein oligomers. Company updates commonly address dementia with Lewy bodies, Alzheimer’s disease, mild cognitive impairment, and geographic atrophy secondary to dry AMD.
Recurring developments include Phase 2 study data from programs such as SHIMMER and START, regulatory interactions with U.S. and European agencies, scientific conference presentations, expanded access activity, and quarterly financial results. News also covers NIH-related grant funding, cash runway commentary, and clinical-development plans tied to zervimesine’s use across central nervous system and retina indications.
Cognition Therapeutics (Nasdaq: CGTX) will host a virtual KOL symposium on June 9, 2022, from 10:00 - 11:30 a.m. ET, focusing on dry age-related macular degeneration (dry AMD). The company plans to initiate a Phase 2 study with its lead candidate, CT1812, in the second half of 2022. Notable speakers include Dr. Mary Hamby and Dr. Karl Csaky, who will discuss recent findings and the current treatment landscape for dry AMD. The event is free to register and will also offer a live Q&A session.
Cognition Therapeutics (Nasdaq: CGTX) announced its participation in the H.C. Wainwright Global Investment Conference from May 23-26, 2022. CEO Lisa Ricciardi and VP of Research Mary Hamby will present on May 25 at 3:30 p.m. EDT. The event will be accessible via a live and archived webcast on both the conference platform and the company's investor website. Registered investors can also schedule one-on-one meetings with management during the conference, aimed at fostering investor relations.
Cognition Therapeutics (NASDAQ: CGTX) announced the commencement of patient dosing in the second cohort of its Phase 2 SHINE study focusing on mild-to-moderate Alzheimer’s disease. The company plans to enroll patients in a dry AMD trial and the START trial in collaboration with the Alzheimer’s Clinical Trials Consortium in the second half of 2022. Financially, the company's Q1 2022 net loss was $3.8 million, or $(0.17) per share, compared to a loss of $0.9 million, or $(1.64) per share, in Q1 2021. As of March 31, 2022, cash reserves stood at $51.5 million.
Cognition Therapeutics, Inc. (NASDAQ: CGTX) announced it will release its financial results for Q1 2022 on May 11, 2022. The company focuses on developing small molecule therapeutics for age-related degenerative diseases, specifically targeting Alzheimer's disease and related conditions with its lead candidate CT1812. Cognition aims to leverage its unique mechanism to regulate impaired pathways in these diseases. The announcement corrects the report date previously stated as May 10, 2022.
Cognition Therapeutics (NASDAQ: CGTX) announced it will report its financial results for Q1 2022 on May 11, 2022. The company focuses on therapies for age-related degenerative diseases in the central nervous system and retina, with its lead candidate CT1812 under investigation for conditions like Alzheimer’s and dry age-related macular degeneration. Cognition aims to innovate treatments by targeting σ-2 receptors, offering a distinct mechanism compared to current therapies.
Cognition Therapeutics (NASDAQ: CGTX) showcased a poster at the ARVO meeting, highlighting that sigma-2 receptor modulators can restore the normal functioning of retinal pigment epithelial (RPE) cells impaired by dry age-related macular degeneration (AMD).
CT1812, Cognition's lead candidate, demonstrated the ability to rescue vital functions of RPE cells in in vitro models. The company plans to initiate a Phase 2 clinical trial with CT1812 in patients with dry AMD in late 2022. Dry AMD affects around 190 million individuals globally, making it a significant health concern.
Cognition Therapeutics (NASDAQ: CGTX) announced its participation in the ARVO 2022 conference, showcasing preclinical results on sigma-2 receptor modulators that protect retinal pigmented epithelium (RPE) cells. Their lead candidate, CT1812, aims to address dry age-related macular degeneration (AMD) and a Phase 2 clinical study is planned. Dry AMD affects approximately 190 million globally, causing significant vision loss. The poster presentation is scheduled for May 3, 2022, highlighting how these modulators can normalize disrupted homeostatic processes in RPE cells.
Cognition Therapeutics, Inc. (Nasdaq: CGTX) announced that its management will participate in a virtual fireside chat at the B. Riley Securities’ Neuro & Ophthalmology Conference on April 27-28, 2022. The discussion will focus on advancements in their clinical programs targeting age-related diseases affecting the central nervous system and retina, particularly their lead candidate, CT1812. A webcast will be available for viewers, outlining the company's ongoing research and development efforts in Alzheimer’s disease and other conditions.
Cognition Therapeutics, Inc. (Nasdaq: CGTX) announced participation in Needham & Company's 21st Annual Virtual Healthcare Conference from April 11-14, 2022. CEO Lisa Ricciardi will provide a corporate update on April 11, 2022, from 3:00 to 3:40 p.m. ET. A live and archived webcast will be available on the company's investor website. The company focuses on developing innovative drugs targeting age-related degenerative diseases affecting the central nervous system and retina, leveraging expertise in sigma-2 receptor mechanisms.
Cognition Therapeutics (NASDAQ: CGTX) reported a solid financial position after raising $52 million through an upsized IPO and securing $169 million in grant funding. The company is advancing its clinical pipeline for Alzheimer’s disease and dementia with Lewy bodies (DLB), with plans for Phase 2 studies in dry AMD and early-stage Alzheimer’s expected to begin in H2 2022. Despite a net loss of $11.7 million in 2021, Cognition's robust cash reserves of $54.7 million are projected to sustain operations through mid-2023.