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Cognition Therapeutics, Inc. develops clinical-stage drug candidates for neurodegenerative disorders, with news centered on zervimesine (CT1812), an investigational oral small molecule designed to protect neuronal synapses from toxic protein oligomers. Company updates commonly address dementia with Lewy bodies, Alzheimer’s disease, mild cognitive impairment, and geographic atrophy secondary to dry AMD.
Recurring developments include Phase 2 study data from programs such as SHIMMER and START, regulatory interactions with U.S. and European agencies, scientific conference presentations, expanded access activity, and quarterly financial results. News also covers NIH-related grant funding, cash runway commentary, and clinical-development plans tied to zervimesine’s use across central nervous system and retina indications.
Cognition Therapeutics, Inc. (Nasdaq: CGTX) plans to announce its fourth quarter and full year financial results for 2021 on March 30, 2022, before market open. Following this release, the company will host a conference call at 8:00 a.m. ET to discuss the results and provide a business update. Participants can join via telephone or an audio webcast accessible on the company’s website. Cognition focuses on developing innovative therapeutics targeting age-related degenerative diseases.
Cognition Therapeutics (CGTX) is showcasing findings from its clinical development program for CT1812, a sigma-2 receptor modulator targeting Alzheimer's disease, at the AD/PD™ 2022 conference in Barcelona from March 15-20, 2022. Results from the Phase 1b SNAP study indicate significant beta amyloid oligomer displacement into cerebrospinal fluid after CT1812 administration, contrasting with placebo results. Additionally, preliminary findings from the Phase 2 SHINE study highlight potential pharmacodynamic biomarkers linked to Alzheimer's treatment. Full SNAP results will be published in a peer-reviewed journal later this year.
Cognition Therapeutics (Nasdaq: CGTX) announces CEO Lisa Ricciardi's participation in two healthcare conferences. The Oppenheimer 32nd Annual Healthcare Conference will take place on March 16, 2022, at 4:00 p.m. ET, with a live webcast available for 90 days. The Sachs Neuroscience Innovation Forum, focusing on Alzheimer's and dementia, is scheduled for March 22, 2022, at 10:00 a.m. ET, also offering live and on-demand access for registered participants. One-on-one meetings with Ricciardi can be scheduled through event representatives.
Cognition Therapeutics (Nasdaq: CGTX) announced that Anthony Caggiano, M.D., Ph.D., will participate in the BIO CEO & Investor Conference on February 15, 2022, discussing neurodegenerative therapeutics. This panel aims to explore innovative partnerships in the field following a significant investment surge in neuroscience in 2020. Dr. Caggiano emphasized the renewed interest in therapies targeting biological pathways in neurological diseases, highlighting their sigma-2 receptor modulators. The event will be webcasted for registered attendees.
Cognition Therapeutics (Nasdaq: CGTX) announced significant achievements for 2021, including an upsized IPO that generated approximately $52 million and $45 million in grants from the National Institute on Aging for clinical studies. The company appointed new leadership for R&D and expanded its clinical pipeline, demonstrating clinical engagement in Alzheimer's and other neurodegenerative diseases. Looking ahead, Cognition aims to advance multiple studies funded by substantial grants and deliver new therapeutics to enhance shareholder value in 2022.
Cognition Therapeutics (NASDAQ: CGTX) has received a Therapeutic Pipeline Program Grant from The Michael J. Fox Foundation for Parkinson's Research. This funding will support preclinical studies of two sigma-2 receptor modulators in animal models of Parkinson's disease, led by VP of research Mary E. Hamby, Ph.D. The studies aim to develop disease-modifying therapies for Parkinson's, where current options are lacking. CEO Anthony Caggiano emphasized the potential of σ-2 receptor targeting to impact disease progression biomarkers.
Cognition Therapeutics (Nasdaq: CGTX) announced that Lisa Ricciardi, CEO, will participate as a panelist in a virtual discussion titled, "Aduhelm: Stimulating the Next Generation of AD Treatment" on January 11, 2022, from 8:00 to 9:00 a.m. PT.
The panel focuses on the evolving investment landscape in Alzheimer's disease treatments, featuring CEOs from five companies in the sector. Cognition's key product, CT1812, is in Phase 2 development and has received FDA Fast Track designation for Alzheimer's.
Cognition Therapeutics, Inc. (Nasdaq: CGTX) will hold a virtual R&D symposium on December 7, 2021, from 10:00 am to 12:00 pm ET. The event will focus on dementia with Lewy bodies (DLB), featuring presentations by experts from the DLB community, including insights on treatment and patient burden.
Cognition's management will discuss advancing their small molecule sigma-2 modulator for DLB. Registration is available on their website, and a live webcast will be provided.
Cognition Therapeutics (Nasdaq: CGTX) announced significant financial results for the third quarter ended September 30, 2021, following its upsized IPO which raised approximately $52 million. The firm received NIA grants totaling $43.6 million to support clinical studies for its lead candidate, CT1812, targeting mild-to-moderate Alzheimer’s disease and dementia with Lewy bodies. They reported a net loss of $5.0 million for Q3, with increased R&D expenses of 8.1% and overall optimistic projections for clinical advancements. The firm maintains a cash reserve of $8.3 million and positive funding outlook for the next 24 months.
Cognition Therapeutics, Inc. (Nasdaq: CGTX) has closed the sale of 565,217 additional shares of common stock following the full exercise of the underwriters' over-allotment option related to its initial public offering. The shares were sold at $12.00 each, raising approximately $6.8 million before expenses. With this over-allotment, the total offering comprises 4,333,333 shares, generating about $52 million in gross proceeds. The IPO commenced trading on October 8, 2021.