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Coherus Oncology, Inc. reports commercial-stage oncology developments centered on LOQTORZI® (toripalimab-tpzi), an approved next-generation PD-1 inhibitor for recurrent or metastatic nasopharyngeal carcinoma. Company updates also cover its antibody immunotherapy pipeline, including tagmokitug, an anti-CCR8 cytolytic antibody, and casdozokitug, an IL-27 antagonistic antibody, across solid-tumor programs such as liver, prostate, head and neck, colorectal, gastric and esophageal cancers.
Recurring news includes financial results, LOQTORZI revenue commentary, clinical-development updates, strategic partnerships, investor-conference presentations, public common-stock offerings, debt reduction and other capital-structure actions tied to the company's transition from biosimilars to innovative oncology.
Coherus BioSciences, Inc. (NASDAQ: CHRS) has announced that it will release its second quarter 2024 financial results after market close on Thursday, August 8, 2024. The company's management team will host a conference call and webcast at 5:00 p.m. EDT on the same day to discuss the results and provide a general business update.
Investors and interested parties can pre-register for the conference call to receive dial-in information and a personal PIN. A live webcast will be available, and a replay will be accessible on the company's investor relations website. The press release containing the financial results and related materials will be available on the Coherus website before the start of the conference call.
On June 27, 2024, Coherus BioSciences (Nasdaq: CHRS) announced the divestiture of YUSIMRY (adalimumab-aqvh) to Hong Kong King-Friend Industrial Co. (HKF) for $40 million in an all-cash deal. The transaction, completed on June 26, 2024, aligns with Coherus' strategic focus on oncology.
Meitheal Pharmaceuticals, a wholly owned subsidiary of HKF, will continue the commercialization of YUSIMRY in the U.S. Coherus plans to use the proceeds to strengthen its cash position and further its oncology initiatives.
Coherus' oncology portfolio includes LOQTORZI (toripalimab-tpzi), an FDA-approved PD-1 inhibitor, and the UDENYCA (pegfilgrastim-cbqv) franchise with three FDA-approved presentations, along with a clinical-stage immuno-oncology portfolio.
Coherus BioSciences (CHRS) has appointed Rita Karachun, CPA, CGMA, to its Board of Directors, effective May 31, 2024. Karachun, a seasoned financial expert with nearly four decades of experience, previously served as SVP and Global Controller at Merck. At Merck, she managed a global team responsible for the company's accounting and operational aspects. Coherus believes her extensive background in finance, accounting, and operational transformation will significantly benefit the company's strategic direction and pipeline advancement. CEO Denny Lanfear expressed confidence in Karachun's ability to contribute to Coherus's growth and transformation.
Coherus BioSciences (Nasdaq: CHRS) will present at the 2024 Jefferies Global Healthcare Conference on June 6, 2024, at 8:30 a.m. EDT/5:30 a.m. PDT.
Senior management will discuss the company's latest developments and strategies.
The presentation can be accessed via a webcast on the Coherus website, and it will be available for replay until July 7, 2024.
Coherus BioSciences announced preliminary Phase 1 results for CHS-114, an anti-CCR8 antibody, at the 2024 ASCO Annual Meeting. CHS-114 exhibited an acceptable safety profile with no dose-limiting toxicities in heavily pretreated patients with solid tumors. Selective depletion of CCR8+ Tregs was maintained, establishing proof of mechanism. One patient experienced Grade 2 colitis as a serious adverse event. Pharmacokinetic data showed dose proportional exposure and a linear elimination half-life of about 10 days. The results support further evaluation of CHS-114 in combination with toripalimab and other immuno-oncology agents. No objective responses were noted, but a stable disease rate of 47% was observed in 19 evaluable patients.
Coherus BioSciences (Nasdaq: CHRS) has announced that its senior management will present at the TD Cowen 5th Annual Oncology Innovation Virtual Summit. This event, set for May 29, 2024, at 12:00 p.m. EDT, will provide insights ahead of the ASCO and EHA conferences. The presentation will be available via webcast through the Coherus website until June 26, 2024. This offers an opportunity for investors and stakeholders to gain valuable insights from Coherus' management team. For more information, investors can reach out to Jami Taylor, Head of Investor Relations at Coherus.
Coherus BioSciences reported net revenue of $77.1 million in Q1 2024, with significant increases in UDENYCA sales and LOQTORZI launch. The company entered into a partnership for toripalimab development, replaced term loan with new debt, and presented positive clinical data. Despite increased expenses, Coherus showed a strong financial performance, with net income of $102.9 million and cash reserves of $259.8 million.
Coherus BioSciences, Inc. announced the full repayment of a $75 million term loan through a new combined term loan and product royalty financing agreement with Barings. This move reduces the Company's term loan debt by half, with a new maturity date of May 2029. The transaction also included a $37.5 million royalty monetization financing based on future sales of LOQTORZI® and UDENYCA®.
Coherus BioSciences, Inc. announced a clinical collaboration with the Cancer Research Institute (CRI) to explore a combination of LOQTORZI (toripalimab-tpzi) with ENB-003 for the treatment of ovarian cancer. The iPROC platform study aims to investigate the potential benefits of this innovative combination in drug-resistant cancers. The selection of LOQTORZI and ENB-003 for this study is supported by strong preclinical and clinical data, with a focus on advancing meaningful solutions for patients.
Coherus BioSciences, Inc. (NASDAQ: CHRS) will report its first quarter 2024 financial results on May 9, 2024. The management team will host a conference call and webcast to discuss the results and business update. Investors can access the webcast replay and related materials on the Coherus website.