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ClearPoint Neuro Announces FDA Clearance of the Velocity Alpha(R) MR High Speed Surgical Drill System and First Clinical Use, Further Expanding Our Drug Delivery Ecosystem and Global Footprint

(Very Positive)

ClearPoint Neuro (NASDAQ:CLPT) announced FDA 510(k) clearance of the Velocity Alpha MR High Speed Surgical Drill and reported the system's first clinical use on April 22, 2026 in a four-trajectory procedure. The drill integrates with ClearPoint's SmartFrame navigation and is manufactured by adeor medical AG.

The device is designed for multi-trajectory, MR and OR workflows, aims to streamline procedures, and is expected to be compatible with ClearPoint's robotic navigation platform now in development.

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Positive

  • Received FDA 510(k) clearance for Velocity Alpha MR drill
  • Completed first clinical use on April 22, 2026 (four-trajectory procedure)
  • Integration with SmartFrame navigation for multi-trajectory procedures

Negative

  • Device manufactured by third party adeor medical AG, implying supply dependence
  • Robotic navigation compatibility is prospective and currently in development

News Market Reaction – CLPT

-2.18%
11 alerts
-2.18% Session close to close
+6.4% Peak in 3 min
$329.55M Market Cap
0.0x Rel. Volume

In the Apr 23 session, CLPT declined 2.18%, reflecting a moderate negative market reaction. Argus tracked a peak move of +6.4% during that session. Our momentum scanner triggered 11 alerts that day, indicating notable trading interest and price volatility.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement adds an FDA-cleared, MR-compatible high-speed surgical drill that integrates with ...
Analysis

This announcement adds an FDA-cleared, MR-compatible high-speed surgical drill that integrates with ClearPoint’s SmartFrame platform, supporting multi-trajectory, cell- and gene-therapy procedures. It builds on earlier FDA clearances for navigation software and Prism accessories, further connecting the company’s neurosurgical ecosystem. Investors may track adoption in complex clinical workflows, progress toward robotic platform compatibility, and how these tools support broader commercial use of partnered biologic and gene-therapy programs.

Key Figures

Procedure trajectories: 4 trajectories
1 metrics
Procedure trajectories 4 trajectories First clinical procedure using Velocity Alpha MR High Speed Surgical Drill

Previous Clinical trial,fda approval Reports

3 past events · Latest: Sep 04 (Positive)
Same Type Pattern 3 events
Date Event Sentiment 24h Move Catalyst
Sep 04 FDA clearance update Positive -0.3% 510(k) clearance expanding Prism laser therapy compatibility to 1.5T MRI.
Jan 27 FDA software clearance Positive +5.5% ClearPoint Navigation 3.0 cleared to add intraoperative CT and Conebeam CT.
Apr 29 FDA accessory clearance Positive +1.3% Prism Bone Anchor Accessory cleared, enabling OR laser therapy navigation.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Past FDA/clinical-platform clearances generally saw modest price moves, with one small negative and two positive reactions, indicating mixed but usually contained trading responses.

Recent Company History

Recent history shows a series of regulatory and platform-expansion milestones. Prior same-tag FDA 510(k) clearances for Prism and navigation software (on Jan 27, 2025 and Sep 4, 2025) modestly moved the stock, with one small decline and two gains. These events, like today’s drill clearance and first clinical use, consistently expand ClearPoint’s neurosurgical and therapy-delivery ecosystem in MRI/OR settings.

Key Terms

510(k)-cleared, pneumatic drill
2 terms
510(k)-cleared regulatory
"first clinical procedure utilizing the 510(k)-cleared Velocity Alpha MR High Speed"
A 510(k)-cleared device is a medical device that the U.S. Food and Drug Administration has reviewed and found to be substantially equivalent to a legally marketed device, allowing it to be sold without undergoing the more rigorous premarket approval process. For investors, 510(k) clearance is a regulatory green light that reduces time and uncertainty before commercial sales—like passing a safety inspection that lets a product enter stores—while still carrying different regulatory expectations than full approval.
pneumatic drill technical
"it is a versatile pneumatic drill system designed to streamline ClearPoint"
A pneumatic drill is a heavy-duty tool powered by compressed air that delivers rapid hammering blows to break rock, concrete or pavement — like an air-driven jackhammer used for digging or demolition. Investors watch mentions of pneumatic drills because they signal active construction, mining or infrastructure work, which can affect a company’s revenue prospects, equipment and materials demand, project timelines and capital spending.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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SOLANA BEACH, CA / ACCESS Newswire / April 22, 2026 / ClearPoint Neuro, Inc. (NASDAQ:CLPT) ("Company"), a global device, cell, and gene therapy-enabling company offering precise navigation to the brain and spine, today announced the successful completion of the first clinical procedure utilizing the 510(k)-cleared Velocity Alpha MR High Speed Surgical Drill System. Utilized in a four-trajectory clinical trial procedure, the system highlights its scalability and potential to support a broader range of programs within the Company's partnered biologics portfolio.

The Velocity Alpha MR High Speed Surgical Drill is manufactured by a German-based surgical equipment leader, adeor medical AG, and it is a versatile pneumatic drill system designed to streamline ClearPoint procedures and improve case efficiency in both MR and Operating Room environments. The new drill is purpose-built to uniquely integrate with ClearPoint Neuro's SmartFrame navigation platform, featuring specialized drill bits and cutters - further differentiating it from conventional surgical drills. Designed primarily to support multi-trajectory procedures, including investigational cell- and gene-therapy cases, it integrates into procedural workflows for complex neurosurgical applications.

The addition of the new drill reflects the Company's strategy to broaden its product portfolio with complimentary technologies designed to function cohesively across ClearPoint Neuro procedures, supporting a more connected ecosystem and long-term growth. In the future, the Company expects the drill to be compatible with its robotic navigation platform, which is currently in development.

"The design of the drill bits provides tactile feedback during bone access, and facilitates consistent, predictable opening of the skull even during minimally invasive procedures where the bone is not fully visualized," said Dr. Paul Larson, Professor of Neurosurgery at University of Arizona/Banner University Medical Center-Tucson and the Company's Chief Medical Officer. "For my cases that involve multiple trajectories, its integration with the SmartFrame platform has the potential to reduce my procedure times by an hour or more."

"This new drill will expand our ability to support complex therapeutic workflows such as advanced clinical trials, as well as established workflows like DBS and LITT," said Nate Williams, Director of Research and Development at ClearPoint Neuro. "We believe solutions like this can help our neurosurgeon customers perform cases more efficiently today and provides a clear pathway to scale across surgical environments and toward broader commercial adoption of therapies."

"High-speed surgical drilling and cranial access have been at the core of what we do at adeor medical AG for decades. The Velocity Alpha MR high-speed system is a product that truly reflects this experience - built by a team that knows the neurosurgical environment inside out. We deeply value our partnership with ClearPoint Neuro and are genuinely proud to play a role in contributing to further streamline the surgical workflow for their SmartFrame navigation platform. Seeing this newly developed drill achieve FDA clearance and perform well in the first clinical use is exactly the kind of outcome we work towards," said Dominic Hasbach, Chief Executive Officer of adeor medical AG.

About the Velocity Alpha® MR High Speed Surgical Drill System

The Velocity Alpha MR High Speed Surgical Drill System is 510(k) cleared by the FDA for use in the United States for trephination, incision, cutting, removal, shaping, and sawing of soft and hard tissue, bone and biomaterials in or near a magnetic field of 3.0 Tesla or less for use in Neurosurgery. A universal cutter system with one-click coupling and integrated telescoping functionality is designed to support the needs of today's OR personnel. The system is designed for ease of handling and operates at up to 80,000 rpm with a low noise profile.

About ClearPoint Neuro

ClearPoint Neuro is a device, cell, and gene therapy-enabling company offering precise navigation to the brain and spine. The Company uniquely provides both established clinical products as well as preclinical development services for controlled drug and device delivery. The Company's flagship product, the ClearPoint Neuro Navigation System, has FDA clearance and is CE-marked. ClearPoint Neuro is engaged with healthcare and research centers in North America, Europe, Asia, and South America. The Company is also partnered with the most innovative pharmaceutical/biotech companies, academic centers, and contract research organizations, providing solutions for direct central nervous system delivery of therapeutics in preclinical studies and clinical trials worldwide. To date, thousands of procedures have been performed and supported by the Company's field-based clinical specialist team, which offers support and services to our customers and partners worldwide. For more information, please visit www.clearpointneuro.com.

Disclosure Statement: Dr. Paul Larson is the Chief Medical Officer at ClearPoint Neuro.

Forward Looking Statements

This press release contains forward-looking statements within the context of the federal securities laws, including the Company's expectation for the future market of the Velocity Alpha MR High Speed Surgical Drill System, and the product's other performance and results, including the product's ability to reduce procedural time, streamline complex workflows, enhance overall case efficiency, and advance commercial adoption of therapies. These forward-looking statements are based on management's current expectations and are subject to the risks inherent in the business, which may cause the Company's actual results to differ materially from those expressed in or implied by forward-looking statements. Particular uncertainties and risks include those relating to: the Company's ability to market, commercialize and achieve broader market acceptance for new products and services offered by the Company; the ability of our biologics and drug delivery partners to achieve commercial success, including their use of the Company's products and services in their delivery of therapies; the Company's ability to maintain its current relationships with biologics and drug delivery partners or enter into new relationships with such partners; the Company's expectations, projections and estimates regarding expenses, future revenue, capital requirements, and the availability of and the need for additional financing; the Company's ability to obtain additional funding to support its research and development programs; the ability of the Company to manage the growth of its business; the Company's ability to attract and retain its key employees; and risks inherent in the research, development, and regulatory approval of the Company's new products. For a detailed description of the Company's risks and uncertainties, you are encouraged to review its documents filed with the SEC including the Company's recent filings on Form 8-K, Form 10-K and Form 10-Q. You are cautioned not to place undue reliance on forward-looking statements, which speak only as of the date on which they were made. The Company undertakes no obligation to update such statements to reflect events that occur or circumstances that exist after the date on which they were made, except as required by law.

Contact Information

Investor Relations:
Danilo D'Alessandro, Chief Financial Officer
(888) 287-9109 ext. 3
ir@clearpointneuro.com

SOURCE: ClearPoint Neuro, Inc.



View the original press release on ACCESS Newswire

FAQ

What clearance did ClearPoint Neuro (CLPT) receive for the Velocity Alpha MR drill on April 22, 2026?

ClearPoint Neuro received FDA 510(k) clearance for the Velocity Alpha MR drill. According to ClearPoint Neuro, the clearance authorizes the device for use in MR and OR environments and supports multi-trajectory neurosurgical workflows.

Did ClearPoint Neuro (CLPT) perform a clinical procedure with the Velocity Alpha MR drill?

Yes. ClearPoint Neuro completed the first clinical use on April 22, 2026 in a four-trajectory procedure. According to ClearPoint Neuro, that initial case demonstrated the drill's integration with the SmartFrame navigation platform.

Who manufactures the Velocity Alpha MR drill used by ClearPoint Neuro (CLPT)?

The Velocity Alpha MR drill is manufactured by adeor medical AG, a German-based surgical equipment company. According to ClearPoint Neuro, adeor supplies the pneumatic high-speed system designed for MR and operating room use.

How does the Velocity Alpha MR drill integrate with ClearPoint Neuro's systems (CLPT)?

The drill is designed to integrate with the SmartFrame navigation platform for multi-trajectory procedures. According to ClearPoint Neuro, specialized drill bits and cutters enable seamless workflow integration in MR and OR settings.

Will the Velocity Alpha MR drill work with ClearPoint Neuro's robotic navigation platform (CLPT)?

ClearPoint Neuro expects future compatibility between the drill and its robotic navigation platform, which is currently in development. According to ClearPoint Neuro, this compatibility represents a planned pathway rather than an immediate capability.