Cellectar Biosciences Inc Stock Price, News & Analysis

Cellectar Biosciences (NASDAQ: CLRB) has expanded its collaboration with IntoCell Inc. to further develop phospholipid drug conjugates (PDCs). This collaboration utilizes IntoCell's innovative OHPAS linker chemistry alongside Cellectar's phospholipid ethers to create new PDCs. The partnership has demonstrated sufficient preclinical success to proceed with IND-enabling studies. Cellectar retains rights to globally develop any resulting OHPAS-containing PDCs, enhancing its pipeline of targeted cancer therapies.

Cellectar Biosciences (NASDAQ: CLRB) has formed a collaboration with South Korea-based LegoChemBio for developing first-in-class phospholipid drug conjugates (PDCs). This partnership aims to leverage both companies' technologies to create new therapies targeting solid tumors with unmet medical needs. The agreement allows for joint development of three novel PDC candidates and offers options for global commercialization rights. Financial terms remain undisclosed. Both companies are optimistic about enriching their oncology pipelines and advancing cancer treatment.

Cellectar Biosciences, focused on cancer treatment, announced that President and CEO James Caruso will present at the Ladenburg Thalmann 2021 Virtual Healthcare Conference on July 14, 2021, at 3:00 pm. The presentation will detail the company's drug development initiatives, including the CLR 131 treatment for Waldenstrom’s macroglobulinemia. A replay will be available on their website after the event. Cellectar utilizes its proprietary Phospholipid Drug Conjugate™ platform to create targeted cancer therapies, aiming for improved efficacy and safety.

Cellectar Biosciences, Inc. (NASDAQ: CLRB) announced the election of Dr. Asher Alban Chanan-Khan to its board of directors as an independent director. Dr. Chanan-Khan brings extensive experience in oncology, notably in hematologic cancers, and will play a critical role in advancing the company's cancer-targeting assets, including CLR 131. The company continues to focus on developing drugs that leverage its Phospholipid Drug Conjugate™ platform, which aims for improved efficacy in cancer treatment.

Cellectar Biosciences, Inc. (CLRB) presented promising results at the ASCO Annual meeting regarding CLR 131, a treatment for relapsed/refractory B-cell hematologic cancers. The Phase 2 CLOVER-1 study revealed a 100% overall response rate in six patients with Waldenstrom's macroglobulinemia, including an 83.3% major response rate and a 16.7% complete response rate. Notably, mean treatment-free remission is 1.1 years, with progression-free survival not yet reached after 18 months for high-risk patients. The ongoing trial aims to enroll 50 WM patients and explore further efficacy and safety outcomes.

Cellectar Biosciences (NASDAQ: CLRB) has announced a virtual poster presentation at the ASCO Annual Meeting from June 4-8, 2021, detailing findings from its Phase 2a study of CLR 131 in Waldenstrom’s macroglobulinemia (WM). The presentation will highlight results from six patients. Management will host a KOL call with Dr. Sikandar Ailawadhi, the lead investigator, on June 4 at 10:00 am. CLR 131 targets cancer cells using the company’s Phospholipid Drug Conjugate (PDC) delivery platform and is part of a pivotal trial aimed at understanding treatment responses in WM patients.

On May 14, 2021, Cellectar Biosciences (NASDAQ: CLRB) announced its participation in the Oppenheimer Rare & Orphan Disease Summit on May 21, 2021. The company will be available for one-on-one meetings and will host an on-demand presentation for registered participants. Cellectar is focused on developing cancer-targeted therapies using its proprietary Phospholipid Drug Conjugate™ delivery platform. The company’s product pipeline includes CLR 131 and other preclinical PDC programs aimed at enhancing treatment efficacy and safety for cancer patients.

Cellectar Biosciences, Inc. (NASDAQ: CLRB) announced a pivotal study initiation of CLR 131 for Waldenstrom’s macroglobulinemia, titled CLOVER-WaM, aiming to enroll 50 patients. The study is aligned with FDA feedback and focuses on a major response rate.

The company received European Orphan Drug Designation for CLR 131, granting 10 years of market exclusivity. As of March 31, 2021, Cellectar holds approximately $54 million in cash, supporting operations into Q3 2023. Q1 net loss increased to $6.4 million, or $0.13 per share, compared to a loss of $4.0 million, or $0.42 per share, last year.

Cellectar Biosciences (NASDAQ: CLRB) announced the grant of a new patent titled "Phospholipid-Ether Analogs as Cancer-Targeting Drug Vehicles" by patent authorities in Eurasia, Australia, and Mexico. This patent provides protection for their phospholipid-ether (PLE) analogs used in combination with various small molecule chemotherapies. CEO James Caruso highlighted the patent's role in enhancing their phospholipid drug conjugate (PDC) platform, aimed at improving drug efficacy and safety in cancer treatment. Their lead candidate, CLR 131, is in pivotal clinical studies for hematologic cancers.