Welcome to our dedicated page for Cellectar Biosciences news (Ticker: CLRB), a resource for investors and traders seeking the latest updates and insights on Cellectar Biosciences stock.
Cellectar Biosciences, Inc. (NASDAQ: CLRB) is a late-stage clinical radiopharmaceutical company developing targeted cancer drugs based on its proprietary Phospholipid Drug Conjugate (PDC) platform. The CLRB news feed on Stock Titan aggregates company announcements, scientific presentations and regulatory updates that reflect the progress of this oncology pipeline.
Investors and researchers following Cellectar’s news can track developments around its lead asset, iopofosine I 131, including data from the CLOVER WaM Phase 2b study in Waldenstrom’s macroglobulinemia, the CLOVER‑2 pediatric high‑grade glioma program, and investigator‑initiated work in head and neck cancer. News items also cover FDA designations such as Breakthrough Therapy, Orphan Drug, Rare Pediatric Disease and Fast Track, as well as EMA PRIME and orphan designations and feedback from the EMA’s Scientific Advice Working Party on a potential Conditional Marketing Authorization filing in Europe.
The CLRB news stream highlights updates on Auger‑ and alpha‑emitting candidates CLR 121125 (CLR 125) and CLR 121225 (CLR 225), including preclinical data in triple‑negative breast cancer and pancreatic ductal adenocarcinoma, clinical trial planning, and supply agreements for key radioisotopes like actinium‑225 and astatine‑211. Financial results, capital raises, warrant transactions, and reverse stock split actions reported in SEC‑linked press releases provide additional context on how the company funds its development plans.
By monitoring this page, users can review historical and ongoing disclosures about Cellectar’s clinical results, regulatory interactions, partnerships and financing activities, all drawn from company-issued news and related filings.
Cellectar Biosciences (Nasdaq: CLRB) announced a reverse stock split effective July 22, 2022, consolidating every ten shares into one new share. Post-split, approximately 6.1 million shares will be outstanding while the ticker symbol and par value remain unchanged. Stockholder rights will stay the same except for fractional shares, which will be cashed out. The company aims to enhance its share value and improve trading liquidity amid its ongoing development of targeted cancer therapies, particularly iopofosine, currently in pivotal clinical studies.
Cellectar Biosciences, Inc. (NASDAQ: CLRB) reported financial results for Q1 2022, emphasizing the continuation of its pivotal Phase 2b trial of iopofosine for Waldenstrom’s macroglobulinemia (WM) after a positive assessment from an independent data monitoring committee. The company had cash and equivalents of $30.6 million as of March 31, 2022. Net loss for the quarter was $6.1 million, down from $6.4 million in Q1 2021. R&D expenses decreased to approximately $3.9 million, while G&A expenses rose to $2.3 million, reflecting increased professional fees.
Cellectar Biosciences (NASDAQ: CLRB) announced that an independent Data Monitoring Committee has completed a futility/efficacy assessment of its pivotal Phase 2b study of iopofosine in Waldenstrom’s macroglobulinemia (WM) and recommended continuation. The study aims to enroll 50 patients, focusing on a primary endpoint of a 20% major response rate. Cellectar noted an encouraging 83.3% major response rate in a prior study. The pivotal trial will assess treatment-free survival and duration of response, further advancing Cellectar's mission in targeted cancer therapies.
Cellectar Biosciences has announced the appointments of Matthew Hagan as Vice President, Marketing and Strategic Alliances, and David Lasecki as Executive Director, Strategic Alliances. Both bring extensive experience in oncology therapeutics, which the company believes will aid its transition to a commercial-stage entity. Cellectar's pivotal trial for iopofosine, targeting Waldenstrom’s macroglobulinemia, is ongoing, with interim data expected soon. The company continues to develop its Phospholipid Drug Conjugate platform, aiming to enhance cancer treatment efficacy while reducing side effects.
Cellectar Biosciences, Inc. (NASDAQ: CLRB) reported its 2021 financial results, showing a net loss of $24.1 million, or $0.43 per share, up from a $15.1 million loss in 2020. The company highlighted data from its Phase 2 CLOVER-1 study of iopofosine I-131, revealing a 45.5% overall response rate in multiple myeloma patients. Notable progress was made in a Phase 1 study involving children with relapsed high-grade gliomas, with positive tumor response and a recommendation to proceed with higher dosing. Cellectar maintains a strong balance sheet with $35.7 million in cash to fund operations into 2023.
Cellectar Biosciences (NASDAQ: CLRB) announced its participation in upcoming investor conferences, including the Roth Capital Partners 34th Annual Conference on March 15, 2022, and the Oppenheimer 32nd Annual Healthcare Conference on March 16, 2022. Both events will feature fireside chats and opportunities for 1x1 meetings with investors. Cellectar is focused on developing innovative cancer treatments using its proprietary Phospholipid Drug Conjugate platform, with ongoing studies on its lead asset, iopofosine, targeting various cancer types, including Waldenstrom's macroglobulinemia and pediatric cancers.
Cellectar Biosciences (NASDAQ: CLRB) has appointed Chad Kolean as Chief Financial Officer and promoted Jarrod Longcor to Chief Operating Officer. Kolean returns after a successful tenure at other companies, aiming to leverage his extensive industry experience. Longcor, with six years at Cellectar, will oversee operations and strategic growth efforts as the company prepares for a potential NDA filing for its drug targeting Waldenstrom’s macroglobulinemia. The company also plans a pivotal trial assessment of its lead compound, iopofosine I-131, in the near future.
Cellectar Biosciences (NASDAQ: CLRB) announced participation in a fireside chat at the H.C. Wainwright Bioconnect conference, scheduled for January 10-13, 2022. CEO Jim Caruso and CBO Jarrod Longcor will discuss company updates, with the chat available on-demand from 7:00 am ET on January 10.
Cellectar is focused on developing targeted cancer therapies, leveraging its proprietary Phospholipid Drug Conjugate™ (PDC) platform. The pipeline includes iopofosine for relapsed or refractory cancers, currently in pivotal studies.
Cellectar Biosciences (NASDAQ: CLRB) presented promising data from 11 patients in its ongoing Phase 2 CLOVER-1 study of iopofosine I-131 for treating refractory multiple myeloma at the ASH Annual Meeting. The trial showed an overall response rate (ORR) of 45.5%, with a clinical benefit rate (CBR) of 72.7% and a disease control rate (DCR) of 100%. In a subgroup of quad/penta drug refractory patients, the ORR reached 80%.
Despite these positive results, cytopenias were noted as the primary adverse events. The company anticipates sharing further data as the study progresses.
On December 8, 2021, Cellectar Biosciences (NASDAQ: CLRB) announced a poster presentation at the ASH Annual Meeting, showcasing data from the ongoing Phase 2 CLOVER-1 study of iopofosine I-131. The study focuses on eleven patients with triple-class refractory multiple myeloma, highlighting preliminary efficacy and safety results. The poster session will occur on December 11, 2021. Iopofosine is designed for targeted cancer treatment and is undergoing multiple clinical studies, including a pivotal trial for Waldenstrom's macroglobulinemia.