Chemomab Therapeutics to Present Nebokitug Clinical Data at Upcoming Scientific Conferences

Rhea-AI Summary

Chemomab Therapeutics (Nasdaq: CMMB) has announced upcoming presentations of clinical data for nebokitug (CM-101) in treating primary sclerosing cholangitis (PSC) at three major scientific conferences.

The presentations will take place at:

• DDW25 (May 3-6, 2025, San Diego) featuring an oral presentation by Dr. Paul Pockros on safety, tolerability, and biomarker improvements
• EASL 2025 (May 7-10, 2025, Amsterdam) with two poster presentations by CEO Adi Mor on pharmacokinetics, pharmacodynamics, and proteomic profile changes
• BSG LIVE'25 (June 23-26, 2025, Glasgow) featuring an oral presentation by Prof. Douglas Thorburn on the SPRING Study results

The presentations will focus on CM-101's impact on inflammation, fibrosis, and cholestasis in PSC patients.

TEL AVIV, Israel, April 21, 2025 (GLOBE NEWSWIRE) -- Chemomab Therapeutics, Ltd., (Nasdaq: CMMB), a clinical stage biotechnology company developing innovative therapeutics for fibro-inflammatory diseases with high unmet need, today announced that clinical data on nebokitug (CM-101) for the treatment of patients with primary sclerosing cholangitis (PSC) will be presented at major upcoming scientific conferences including DDW25, Digestive Disease Week 2025^®; EASL 2025, the Annual Congress of the European Association for the Study of the Liver; and BSG LIVE'25, the British Society of Gastroenterology’s annual meeting. Chemomab will report information on the content of the presentations after the meeting embargoes lift.

DDW25, May 3-6, 2025, San Diego, USA
Date:	May 4, 2025
Time:	4:00 - 5:30pm PDT
Format:	Oral presentation: CM-101, a novel monoclonal antibody targeting CCL24, was safe, well-tolerated and showed improvements of biomarkers associated with inflammation, fibrosis and cholestasis in patients with primary sclerosing cholangitis (PSC): The Spring Study
Presenter:	Paul Pockros, MD, Director, Liver Disease Scripps Clinic and SC Liver Disease Consortium
Session:	Liver & Biliary Section Distinguished Abstract Plenary
Information:	https://ddw.org/
EASL 2025, May 7-10, 2025, Amsterdam, Netherlands
Date:	May 8, 2025
Time:	8:30-17:30 CEDT
Format:	Poster presentation: CM-101 impacts disease biomarkers in primary sclerosing cholangitis: assessment of the SPRING study pharmacokinetics and pharmacodynamics
Presenter:	Adi Mor, PhD, co-founder and CEO, Chemomab
Session:	Immune-mediated and cholestatic disease: Clinical aspects; Abstract #1255
Information:	https://www.easlcongress.eu
EASL 2025, May 7-10, 2025, Amsterdam, Netherlands
Date:	May 9, 2025
Time:	8:30-17:30 CEDT
Format:	Poster presentation: CCL24 blockade alters the proteomic profile of patients with primary sclerosing cholangitis and down-regulates central disease processes
Presenter:	Adi Mor, PhD, co-founder and CEO, Chemomab
Session:	Immune-mediated and cholestatic: Experimental and pathophysiology; Abstract #1243
Information:	https://www.easlcongress.eu
BSG Live’25, June 23-26, 2025, Glasgow, UK
Date:	June 23-26, 2025
Time:	TBD
Format:	Oral presentation: CM-101, a novel monoclonal antibody targeting CCL24, in patients with primary sclerosing cholangitis: results from SPRING Study
Presenter:	Douglas Thorburn, MD, Divisional Clinical Director for Liver and Digestive Health at the Royal Free London NHS Trust and Professor of Hepatology in the Institute for Liver and Digestive Health at UCL
Session:	Liver
Information:	https://live.bsg.org.uk/

     

About Chemomab Therapeutics Ltd.
Chemomab is a clinical stage biotechnology company developing innovative therapeutics for fibro-inflammatory diseases with high unmet need. Based on the unique role of the soluble protein CCL24 in promoting fibrosis and inflammation, Chemomab developed nebokitug (CM-101), a first-in-class dual activity monoclonal antibody that neutralizes CCL24 and has demonstrated disease-modifying potential. In clinical and preclinical studies, nebokitug has been shown to have a favorable safety profile and has been generally well-tolerated, with the potential to treat multiple severe and life-threatening fibro-inflammatory diseases. Chemomab has reported positive results from four clinical trials of nebokitug in patients. Based on positive data from its Phase 2 SPRING trial in primary sclerosing cholangitis (PSC), the company is preparing for potential initiation of a nebokitug PSC Phase 3 trial. The design of Phase 3 calls for a single pivotal trial based on a clinical event primary endpoint that provides a clear and streamlined pathway to potential full regulatory approval. Nebokitug has received FDA and EMA Orphan Drug and FDA Fast Track designations for the treatment of PSC. Chemomab’s nebokitug program for the treatment of systemic sclerosis has an open U.S. IND. For more information, visit: chemomab.com.
  
Contacts:

Media and Investors:
Barbara Lindheim
Consulting Vice President, Investor & Public Relations, Strategic Communications
Phone: +1 917-355-9234
barbara.lindheim@chemomab.com
IR@chemomab.com

FAQ

What clinical data will Chemomab (CMMB) present at the upcoming conferences?

Chemomab will present clinical data on nebokitug (CM-101) for primary sclerosing cholangitis (PSC) treatment, including safety, tolerability, and biomarker improvements in inflammation, fibrosis, and cholestasis.

When and where will the CMMB SPRING Study results be presented in 2025?

The SPRING Study results will be presented at DDW25 in San Diego (May 3-6), EASL 2025 in Amsterdam (May 7-10), and BSG LIVE'25 in Glasgow (June 23-26).

What are the key findings of nebokitug (CM-101) in PSC treatment?

According to the presentation abstracts, CM-101 was safe, well-tolerated, and showed improvements in biomarkers associated with inflammation, fibrosis, and cholestasis in PSC patients.

Who will present the CMMB clinical data at the scientific conferences?

The data will be presented by Dr. Paul Pockros at DDW25, CEO Adi Mor at EASL 2025, and Prof. Douglas Thorburn at BSG LIVE'25.