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Corbus Pharmaceuticals to Present Late Breaking CRB-913 Data from Canyon-1 Study at Obesity Week® 2026

Corbus Pharmaceuticals (CRBP) will present late-breaking CRB-913 Canyon-1 Phase 1B study data at Obesity Week 2026 on November 15, 2026.

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Corbus Pharmaceuticals (CRBP) will present late-breaking CRB-913 Canyon-1 Phase 1B study data at Obesity Week 2026 on November 15, 2026.

Harold Bays will present the poster on efficacy, safety and tolerability from 2:30–3:30 p.m. ET at the Gaylord National Resort & Convention Center in National Harbor, Maryland.

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Market Reaction – CRBP

+1.3% Peak Tracked
$4.12 – $4.52 Day Range
$81.23M Mkt Cap at Last Price

On Oct 22, the day this news came out, the latest delayed price for CRBP is 1.98% below the previous close. Argus tracked a peak move of +1.3% during the session. Our momentum scanner has recorded 4 alerts for this stock so far that day. The latest delayed price is $4.20. Relative volume is very high at 3.5x the average.

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Key Terms

inverse agonist
1 terms
inverse agonist medical
"orally delivered highly peripherally restricted CB1 inverse agonist"
An inverse agonist is a type of drug that binds to a biological receptor and reduces the receptor’s natural, ongoing activity, producing the opposite effect of what an activating drug would do. For investors, this matters because inverse agonists can treat conditions where reducing baseline receptor activity is beneficial, potentially creating distinct clinical uses, regulatory pathways, and market value compared with drugs that merely block or activate the same target; think of it as a brake that not only stops a moving car but pushes it slightly backward.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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NORWOOD, Mass., Oct. 22, 2026 (GLOBE NEWSWIRE) -- Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP), a clinical-stage company focused on new therapies in oncology and obesity, today announced that late breaking data from the CRB-913 Canyon-1 Phase 1B study will be presented as a poster presentation at Obesity Week® 2026, taking place from November 14–17, 2026 in National Harbor, MD.

Title: Efficacy, Safety, and Tolerability of CRB-913 in the Ph1b CANYON-1 Study
Presenter: Harold Bays, M.D, Louisville Metabolic and Atherosclerosis Research Center
Date/Time: November 15, 2026, 2:30 p.m. – 3:30 p.m. ET
Location: Gaylord National Resort & Convention Center: Exhibit Hall BCD

About Corbus
Corbus Pharmaceuticals Holdings, Inc. is a clinical-stage company focusing on new therapies in oncology and obesity and is committed to helping people defeat serious illness by bringing innovative scientific approaches to well-understood biological pathways. Corbus’ pipeline includes CRB-701, a next-generation antibody drug conjugate for the treatment of Nectin-4-expressing tumors, and CRB-913, an orally delivered highly peripherally restricted CB1 inverse agonist for the treatment of obesity. Corbus is headquartered in Norwood, Massachusetts. For more information on Corbus, visit corbuspharma.com. Connect with us on X, LinkedIn and Facebook.

Forward-Looking Statements
This press release contains certain forward-looking statements within the meaning of the safe harbor provisions of the Private Securities Litigation Reform Act of 1995, as amended, including statements relating to the timing and occurrence of the presentation of data from the CANYON-1 study, the data to be presented, and the Company’s clinical development plans for CRB-913, and other statements that are predictive in nature. These forward-looking statements are based on current expectations, estimates, forecasts and projections about the industry and markets in which the Company operates and management's current beliefs and assumptions.

These statements may be identified by the use of forward-looking expressions, including, but not limited to, "expect," "anticipate," "intend," "plan," "believe," "estimate," "potential,” "predict," "project," "should," “will,” "would" and similar expressions and the negatives of those terms. These statements relate to future events and involve known and unknown risks, uncertainties, and other factors, which may cause actual results, performance or achievements to be materially different from any future results, performance or achievements expressed or implied by the forward-looking statements. Such factors include, among others, the risk that the timing of the presentation may change; that results from early-stage clinical trials, including the CANYON-1 study, may not be predictive of results in later-stage or larger trials; that interim, preliminary or topline data may change as additional patient data become available or are subject to further analysis; and those set forth in the Company's filings with the Securities and Exchange Commission, including those described in the Company’s Annual Report on Form 10-K for the year ended December 31, 2025, its subsequent Quarterly Reports on Form 10-Q, and other filings the Company makes with the Securities and Exchange Commission. Readers are cautioned not to place undue reliance on such forward-looking statements, which speak only as of the date of this press release. The Company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise, except as required by law.

All product names, logos, brands and company names are trademarks or registered trademarks of their respective owners. Their use does not imply affiliation or endorsement by these companies.

INVESTOR CONTACTS:
Sean Moran
Chief Financial Officer
Corbus Pharmaceuticals
smoran@corbuspharma.com

Dan Ferry
Managing Director
LifeSci Advisors, LLC
daniel@lifesciadvisors.com

MEDIA CONTACT:
Liz Melone
Founder & Principal
Melone Communications, LLC
liz@melonecomm.com


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