Welcome to our dedicated page for Corbus Pharmaceu news (Ticker: CRBP), a resource for investors and traders seeking the latest updates and insights on Corbus Pharmaceu stock.
Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) is a clinical-stage oncology and obesity company whose news flow is driven by clinical trial progress, regulatory milestones, and capital markets activity. The company regularly issues press releases on Phase 1 and Phase 2 data for its investigational drug candidates, as well as updates on financing transactions and participation in major healthcare conferences.
Investors following CRBP news can expect detailed updates on CRB-701, Corbus’ Nectin-4–targeting antibody-drug conjugate being studied in a multi-center Phase 1/2 trial in advanced solid tumors such as head and neck squamous cell carcinoma, cervical cancer, and metastatic urothelial cancer. News items have highlighted objective response rates, disease control rates, safety findings, and Fast Track designations granted by the U.S. Food and Drug Administration. Corbus also announces presentations of CRB-701 data at scientific meetings like the European Society for Medical Oncology Congress and associated key opinion leader events.
Another major news theme is the company’s obesity program, particularly CRB-913, a highly peripherally restricted oral CB1 receptor inverse agonist. Corbus has reported results from a Phase 1a SAD/MAD study in the United States, including safety, tolerability, pharmacokinetic data, and emerging evidence of weight loss in people with obesity. Subsequent news covers the initiation and design of the 12‑week CANYON‑1 Phase 1b study in obese, non-diabetic participants.
Corbus’ news feed also includes quarterly financial results, preliminary financial updates via Form 8‑K, and announcements of underwritten public offerings of common stock and pre-funded warrants. In addition, the company frequently discloses its participation in investor conferences and healthcare symposia, where it presents corporate overviews and engages in one-on-one investor meetings. Bookmarking the CRBP news page on Stock Titan allows readers to track these clinical, regulatory, and financing developments in one place.
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Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) is set to host a virtual 'Meet the Expert' event on April 25, 2023, at 11:00 AM ET. The focus will be on CRB-601, an anti-integrin monoclonal antibody targeting Transforming Growth Factor β (TGFβ) in oncology. Featuring notable researchers Dr. Jeffrey Clarke and Dr. Joan Seoane, the session will highlight CRB-601's potential to inhibit tumor growth, as evidenced in non-clinical studies. The company plans to submit an Investigational New Drug (IND) application for CRB-601 in the latter half of 2023. This initiative underscores Corbus's commitment to advancing precision oncology by innovating treatments for serious illnesses.
Corbus Pharmaceuticals (NASDAQ: CRBP) recently showcased promising pre-clinical data for its drug CRB-601 at the 2023 AACR annual meeting. The study revealed that CRB-601, an avβ8 blocking antibody, demonstrated dose-dependent antitumor activity and significantly enhanced the efficacy of anti-PD-1 immunotherapy. Additionally, the IND submission for CRB-601 is on track for the second half of 2023. The findings highlighted a notable increase in immune cell populations within tumors, along with a blockade of the TGFβ signaling pathway. The combination therapy showed substantial tumor growth inhibition in pre-clinical models, suggesting a strong potential for CRB-601 in cancer treatment.
Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) announced that pre-clinical data for its avβ8 blocking antibody, CRB-601, has been accepted for presentation at the 2023 American Association for Cancer Research annual meeting in Orlando, FL, from April 14-19, 2023.
The poster presentation is titled CRB-601, an avβ8 blocking antibody, prevents activation of TGFβ and exhibits anti-tumor activity associated with immune cell remodeling of the tumor microenvironment and will occur on April 16, 2023, from 1:30 PM - 5:00 PM.
Corbus focuses on innovative treatments targeting well-understood biological pathways in cancer therapy.
Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) has announced significant advancements in its precision oncology pipeline, highlighted by the exclusive licensing of CRB-701, a next-generation Nectin-4 antibody-drug conjugate. CRB-701 is currently in Phase 1 trials in China, targeting advanced solid tumors. Additionally, the company is on track for an IND submission of CRB-601 in late 2023, showcasing promising pre-clinical data. Financially, Corbus reported a net loss of approximately $10.9 million for Q4 2022, slightly worsening from the previous year. Despite these losses, the company maintains $59.2 million in cash, sufficient to fund operations into mid-2024.
Corbus Pharmaceuticals (NASDAQ: CRBP) announced the appointment of Yong Ben, M.D., MBA, to its Board of Directors on March 6, 2023. Dr. Ben brings over 20 years of oncology experience, having led numerous clinical development programs, including drug approvals at renowned companies. His expertise in healthcare venture investment is expected to enhance Corbus' strategic capabilities. The company's recent license agreement for CRB-701 bolsters its position in precision oncology. Corbus aims to advance its pipeline, including CRB-701 and CRB-601, under Dr. Ben's guidance.
Corbus Pharmaceuticals Holdings, Inc. (NASDAQ: CRBP) announced that CEO Yuval Cohen, Ph.D., will present a corporate update and engage in one-on-one investor meetings at the Oppenheimer 33rd Annual Healthcare Conference, hosted virtually from March 13-15, 2023.
The presentation is scheduled for March 14, 2023, at 9:20 a.m. ET. Investors can access the webcast here.
Corbus focuses on precision oncology, with key products including CRB-701 and CRB-601 targeting cancer cells.
Corbus Pharmaceuticals Holdings has entered an exclusive licensing agreement with CSPC Pharmaceutical Group for the development of CRB-701, an antibody drug conjugate targeting Nectin-4. This drug is being developed for various cancers, including urothelial, lung, breast, and prostate. An upfront payment of $7.5 million will be made to CSPC, with potential milestone payments totaling $685 million. The agreement also includes a 1-for-30 reverse stock split effective February 14, 2023, aimed at maintaining compliance with Nasdaq's minimum bid price requirement of $1.00. Corbus aims to initiate US clinical trials in 2024.