Welcome to our dedicated page for CervoMed news (Ticker: CRVO), a resource for investors and traders seeking the latest updates and insights on CervoMed stock.
CervoMed Inc. (CRVO) is a clinical-stage biotechnology company pioneering treatments for neurodegenerative disorders, including dementia with Lewy bodies (DLB). This page serves as the definitive source for official company announcements, research breakthroughs, and clinical development milestones.
Investors and researchers will find timely updates on CervoMed's lead drug candidate neflamapimod, a p38MAPK inhibitor targeting synaptic dysfunction. The curated news collection includes press releases on clinical trial progress, regulatory filings, scientific presentations, and strategic partnerships.
Key updates cover Phase 2b trial developments, biomarker validation studies, and expert analyses of neurodegenerative disease mechanisms. All content is sourced directly from CervoMed's communications to ensure accuracy and compliance with financial disclosure standards.
Bookmark this page for streamlined access to CervoMed's latest advancements in neurotherapeutics. Regularly updated to reflect new developments, this resource supports informed decision-making for stakeholders tracking innovative neurological treatments.
CervoMed (NASDAQ: CRVO) presented Phase 2b RewinD-LB biomarker data on December 1, 2025 at CTAD showing neflamapimod reduced plasma GFAP, increased the Aβ42/40 ratio, and trended to lower NfL in dementia with Lewy bodies (DLB).
Key controlled comparison used participants who received a higher-bioavailability capsule batch (DP Batch B) during a 32-week open-label extension versus their prior placebo period; GFAP change correlated with clinical CDR-SB change (r=0.35, p=0.036).
CervoMed (NASDAQ: CRVO) announced that neflamapimod will be featured in two presentations at the 18th CTAD conference, Dec 1–4, 2025 in San Diego.
A late-breaking oral presentation on Dec 4, 2:10 p.m. PT will present full results from the Phase 2b RewinD-LB trial at 32 weeks, delivered by Prof. John-Paul Taylor. A poster (Poster 071) on Dec 1–2 reports that neflamapimod significantly lowers plasma GFAP and examines effects on NfL and Aβ42/40. Plasma assays were run at the Neurochemistry Laboratory, Amsterdam UMC under Prof. Charlotte Teunissen.
CervoMed (NASDAQ: CRVO) reported Q3 2025 results and clinical progress on neflamapimod for dementia with Lewy bodies (DLB). The company said it aligned with the FDA on Phase 3 trial design and plans to meet other global regulators before initiating a global pivotal trial in H2 2026. Phase 2b RewinD-LB 32-week data showed a 64% risk reduction in clinically significant worsening (CDR-SB ≥1.5) in patients with low AD co-pathology (p<0.001) and correlated reductions in plasma GFAP biomarker. Cash on hand was $27.3M (Sept 30, 2025), with funding expected into the third quarter of 2026. Q3 net loss was $7.7M.
CervoMed (NASDAQ: CRVO) announced written FDA feedback aligning on key elements of its planned global Phase 3 trial of neflamapimod for dementia with Lewy bodies (DLB).
The company plans a single, randomized, double-blind, placebo-controlled Phase 3 in ~300 DLB patients, starting in the second half of 2026, with 32-week randomized treatment and a 48-week open-label extension. The primary endpoint is change in CDR-SB; participants with Alzheimer’s co-pathology will be excluded by imaging/CSF and a plasma ptau181 cutoff (≥21.0 pg/mL).
CervoMed (NASDAQ: CRVO) appointed David Quigley to its Board of Directors effective Oct 28, 2025. Mr. Quigley is a former Senior Partner at McKinsey & Company who led Life Sciences and Private Capital practices (Senior Partner 2010–2025) and brings strategy, commercial, transaction, and M&A experience.
The appointment aligns with CervoMed’s near‑term corporate priorities: planned Phase 3 in dementia with Lewy bodies (DLB) and anticipated FDA feedback on Phase 3 design in Q4 2025. Management says Quigley’s network and commercial expertise will support Phase 3 planning, partnering, and potential commercialization of neflamapimod following Phase 2b results.
CervoMed (NASDAQ: CRVO) announced that Matthew Winton, Ph.D., Chief Commercial and Business Officer, will present a corporate presentation at the Emerging Growth Conference on Wednesday, October 22, 2025. The virtual presentation is scheduled for 11:25–11:55 AM ET. A live webcast and replay will be available via the provided webcast link and in the Investor section of the CervoMed website.
CervoMed (NASDAQ: CRVO) reported Phase 2b RewinD-LB results on Oct 8, 2025 showing neflamapimod activity in dementia with Lewy bodies (DLB).
In participants with plasma ptau181 <21 pg/mL (low likelihood of Alzheimer’s co-pathology), NFMD/B produced significant within-subject improvement on CDR-SB versus placebo (difference = −1.12, p=0.005) and improved clinical scales during the first 16 weeks of the Extension Phase. NFMD/B reduced risk of clinically meaningful progression by 67% versus NFMD/A over 32 weeks and 75% versus placebo over 16 weeks (both p<0.001).
Plasma GFAP fell with NFMD/B (median −16.7 pg/mL vs +5.8 pg/mL on placebo; median difference −23.1 pg/mL, p=0.016), and GFAP change correlated with CDR-SB change (p=0.036). The company expects FDA feedback on Phase 3 design in Q4 2025.
CervoMed (NASDAQ: CRVO) appointed Matthew Winton, Ph.D., as Chief Commercial and Business Officer on Oct 7, 2025 to strengthen commercialization and corporate growth as the company advances into late‑stage Phase 3 development for neflamapimod in dementia with Lewy bodies (DLB). Dr. Winton brings nearly two decades of CNS commercial experience, including leadership roles at Biogen and Inozyme and involvement in a recent acquisition. CervoMed granted an inducement option for 75,000 shares at an exercise price of $8.62 on Oct 6, 2025 that vests monthly over three years commencing Oct 31, 2025.
CervoMed (NASDAQ: CRVO), a clinical stage company developing treatments for age-related neurologic disorders, announced its participation in the 4th Annual ROTH Healthcare Opportunities Conference in New York, NY.
Company management will join a panel discussion titled "Small Firms Tackling Blockbuster Indications" on Thursday, October 9, 2025, at 8:00 AM ET. The company will also be available for one-on-one meetings with institutional investors during the conference.
CervoMed (NASDAQ: CRVO) highlighted its drug neflamapimod's potential benefits for treating Dementia with Lewy Bodies (DLB) at the 150th Annual American Neurological Association conference. The presentation showcased promising Phase 2b trial results, which demonstrated a significant 74% risk reduction in disease progression compared to placebo in patients with low likelihood of concurrent Alzheimer's Disease pathology.
The company is preparing to initiate a Phase 3 trial for DLB patients and expects to finalize the trial design with the FDA in Q4 2025. The presentation was delivered by Dr. James Galvin, Professor of Neurology and Co-Principal Investigator of the RewinD-LB study.
FAQ
What is the current stock price of CervoMed (CRVO)?
What is the market cap of CervoMed (CRVO)?
