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Castle Biosciences Stock Price, News & Analysis

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Welcome to our dedicated page for Castle Biosciences news (Ticker: CSTL), a resource for investors and traders seeking the latest updates and insights on Castle Biosciences stock.

Castle Biosciences, Inc. (Nasdaq: CSTL) is a diagnostics company focused on molecular tests that guide patient care in dermatologic and gastroenterological disease. The CSTL news feed highlights company announcements, clinical data, financial results and corporate updates that shape how investors and clinicians view its role in precision medicine.

Readers can follow news on Castle’s core test portfolio, including DecisionDx-Melanoma for cutaneous melanoma, TissueCypher Barrett’s Esophagus, DecisionDx-SCC for high-risk cutaneous squamous cell carcinoma, MyPath Melanoma and its suite of tests for uveal melanoma such as DecisionDx-UM, DecisionDx-PRAME and DecisionDx-UMSeq. Coverage also includes updates on AdvanceAD-Tx, the company’s gene expression profile test designed to guide systemic treatment decisions in moderate-to-severe atopic dermatitis.

In addition to product and clinical evidence updates, CSTL news items feature quarterly and annual financial results, test volume trends for core revenue drivers, and guidance ranges reported in earnings releases. Regulatory and corporate governance developments, such as bylaw amendments disclosed in Form 8-K filings, as well as participation in healthcare and investor conferences, are also common topics.

Because Castle Biosciences emphasizes rigorous clinical validation, many news releases center on new studies, meta-analyses and expert consensus papers that evaluate the performance of its tests in real-world and prospective cohorts. These articles provide insight into how DecisionDx-Melanoma, TissueCypher and other assays are being integrated into clinical decision-making.

For investors, clinicians and researchers tracking CSTL, this news page offers a centralized view of earnings announcements, product launches, reimbursement developments, clinical data presentations and corporate events related to Castle Biosciences’ molecular diagnostics business.

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Castle Biosciences, Inc. (CSTL) announced that the Centers for Medicare & Medicaid Services (CMS) granted Advanced Diagnostic Laboratory Test (ADLT) status for its TissueCypher Barrett’s Esophagus test, effective March 24, 2022. This status allows for Medicare reimbursement, expanding access for patients at risk of esophageal cancer. TissueCypher is designed to predict the development of high-grade dysplasia and/or esophageal cancer in patients with Barrett’s esophagus. This is Castle's fourth test to achieve ADLT status.

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Castle Biosciences (Nasdaq: CSTL) announced its participation in the 2022 American Academy of Dermatology Annual Meeting in Boston, showcasing its skin cancer gene expression profile tests, DecisionDx-Melanoma and DecisionDx-SCC. These tests provide independent risk stratification for melanoma and cutaneous squamous cell carcinoma, aiding in patient management. DecisionDx-Melanoma predicts metastasis risk using a 31-gene expression profile, while DecisionDx-SCC evaluates risk for high-risk patients using a 40-gene test. Presentations are scheduled for March 26 and 27, 2022, demonstrating their clinical utility.

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Castle Biosciences (CSTL) presented new findings on the performance of its DecisionDx®-Melanoma test at the Society of Surgical Oncology’s 2022 Conference. The study showed that DecisionDx-Melanoma, combined with the proprietary i31-SLNB algorithm, improved predictions of sentinel lymph node (SLN) positivity in melanoma patients compared to traditional T-stage criteria. It demonstrated an Area Under the Curve (AUC) of 0.89 for low-risk tumor identification versus 0.78 for T-stage, highlighting better precision. This advancement could lead to reduced unnecessary procedures and healthcare costs.

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Castle Biosciences, Inc. (NASDAQ: CSTL) has announced that CEO Derek Maetzold and CFO Frank Stokes will present at two upcoming investor conferences: the 42nd Annual Cowen Health Care Conference on March 8, 2022, at 2:50 p.m. Eastern time, and the KeyBanc Capital Markets’ Virtual Life Sciences & MedTech Investor Forum on March 22, 2022, at 9:45 a.m. Eastern time. Live webcasts will be available on the company's website, with replays accessible for two weeks post-event. Castle Biosciences focuses on innovative diagnostic tests to enhance patient care.

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Castle Biosciences (CSTL) reported a significant increase in full-year 2021 revenue, achieving $94.1 million, a 50% rise from 2020. The company's GEP testing volume grew by 55%, with expectations for 2022 revenue between $115-120 million. Key achievements include expanding the commercial team and successful acquisitions in dermatology and gastrointestinal testing markets, which collectively expand the U.S. addressable market by about $1 billion. However, the company faced a net loss of $31.3 million for 2021, highlighting ongoing challenges despite its operational growth.

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Castle Biosciences (CSTL) will announce its fourth quarter and full year 2021 financial results on February 28, 2022, after market close. A conference call and webcast will follow at 4:30 PM ET the same day, providing an opportunity for management to discuss the results and engage in a Q&A session. Investors can access the live event via phone or through the Company’s website. This release highlights the company's dedication to innovative diagnostics aimed at improving patient outcomes.

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Castle Biosciences (NASDAQ: CSTL) announced that CEO Derek Maetzold and CFO Frank Stokes will present at the SVB Leerink Global Healthcare Conference on February 17, 2022, at 3:00 p.m. ET. The presentation will be available via a live audio webcast on the company's website, with a replay accessible for two weeks after the event.

Castle focuses on innovative diagnostics, particularly for skin cancer. Their tests aim to provide personalized and actionable insights to improve treatment decisions and patient outcomes.

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Castle Biosciences (CSTL) announced a collaboration with the National Cancer Institute (NCI) to link its DecisionDx-Melanoma test data with the SEER Program's melanoma case registry. Initial findings show that DecisionDx-Melanoma significantly improves overall survival rates in patients aged 65+ when compared to untested individuals. This data, presented at the 2022 Winter Clinical Dermatology Conference, indicates that patients tested with DecisionDx-Melanoma have a 34% lower risk of death, enhancing the test's clinical relevance. Future collaborations aim to include more recent data.

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Castle Biosciences (NASDAQ: CSTL) will showcase its skin cancer diagnostic tests at Maui Derm for Dermatologists 2022 from January 24-28, 2022, in Maui, Hawaii. Key presentations include the integration of a 31-gene expression profile for melanoma risk assessment and the appropriate use of a 40-gene expression profile test for cutaneous squamous cell carcinoma. The DecisionDx-Melanoma and DecisionDx-SCC tests aim to enhance patient management by predicting metastatic risks. These tests have been validated in numerous studies, indicating their reliability in clinical settings.

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FAQ

What is the current stock price of Castle Biosciences (CSTL)?

The current stock price of Castle Biosciences (CSTL) is $40.01 as of January 19, 2026.

What is the market cap of Castle Biosciences (CSTL)?

The market cap of Castle Biosciences (CSTL) is approximately 1.2B.
Castle Biosciences

Nasdaq:CSTL

CSTL Rankings

CSTL Stock Data

1.17B
27.89M
2.9%
93.07%
5.23%
Diagnostics & Research
Services-medical Laboratories
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United States
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