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Castle Biosciences Stock Price, News & Analysis

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Welcome to our dedicated page for Castle Biosciences news (Ticker: CSTL), a resource for investors and traders seeking the latest updates and insights on Castle Biosciences stock.

Castle Biosciences, Inc. (Nasdaq: CSTL) is a diagnostics company focused on molecular tests that guide patient care in dermatologic and gastroenterological disease. The CSTL news feed highlights company announcements, clinical data, financial results and corporate updates that shape how investors and clinicians view its role in precision medicine.

Readers can follow news on Castle’s core test portfolio, including DecisionDx-Melanoma for cutaneous melanoma, TissueCypher Barrett’s Esophagus, DecisionDx-SCC for high-risk cutaneous squamous cell carcinoma, MyPath Melanoma and its suite of tests for uveal melanoma such as DecisionDx-UM, DecisionDx-PRAME and DecisionDx-UMSeq. Coverage also includes updates on AdvanceAD-Tx, the company’s gene expression profile test designed to guide systemic treatment decisions in moderate-to-severe atopic dermatitis.

In addition to product and clinical evidence updates, CSTL news items feature quarterly and annual financial results, test volume trends for core revenue drivers, and guidance ranges reported in earnings releases. Regulatory and corporate governance developments, such as bylaw amendments disclosed in Form 8-K filings, as well as participation in healthcare and investor conferences, are also common topics.

Because Castle Biosciences emphasizes rigorous clinical validation, many news releases center on new studies, meta-analyses and expert consensus papers that evaluate the performance of its tests in real-world and prospective cohorts. These articles provide insight into how DecisionDx-Melanoma, TissueCypher and other assays are being integrated into clinical decision-making.

For investors, clinicians and researchers tracking CSTL, this news page offers a centralized view of earnings announcements, product launches, reimbursement developments, clinical data presentations and corporate events related to Castle Biosciences’ molecular diagnostics business.

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Castle Biosciences, Inc. (CSTL) has partnered with ModMed to create an interface for their dermatologic electronic health record system, EMA®. This integration allows dermatologic clinicians to order Castle's skin cancer tests directly from patient records, streamlining their workflow. The DecisionDx® suite of tests, which provides actionable information for melanoma and skin cancer management, will be accessible within EMA. This initiative aims to improve patient care and is expected to be operational by the end of 2021.

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Castle Biosciences (NASDAQ: CSTL) has enhanced its DecisionDx-Melanoma test by integrating the new i31-GEP for Risk of Recurrence (i31-ROR) algorithm. This innovation aims to predict five-year outcomes for melanoma-specific survival, distant metastasis-free survival, and recurrence-free survival, improving treatment precision for patients. The company previously launched i31-SLNB to provide risk assessments for sentinel lymph node positivity. Both algorithms utilize tumor-specific data, with validation from over 5,700 samples, promising better patient management and treatment pathways.

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Castle Biosciences (Nasdaq: CSTL) has announced new data validating its DecisionDx® DiffDx™-Melanoma test as an accurate tool for diagnosing challenging melanocytic lesions. Highlighted at the ASDP Annual Meeting (Oct. 20-24), the study demonstrated a high 96% sensitivity and 92.2% specificity, showcasing the test's reliability. When combined with myPath® Melanoma, the diagnostic workflow increased actionable results from 78% to 99%. This advancement enhances diagnostic confidence, improving patient care in uncertain cases.

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Pittsburgh Life Science Greenhouse announced that Castle Biosciences (CSTL) will acquire Cernostics, a company focused on spatial biology and AI-driven tissue biopsy analysis. The acquisition involves an initial payment of $30 million, with additional potential payments of up to $50 million based on performance metrics in 2022. Cernostics is known for its TissueCypher® Barrett's Esophagus Assay, which predicts the risk of high-grade dysplasia and esophageal cancer in Barrett's esophagus patients. The deal is expected to close by year-end 2021.

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Castle Biosciences, Inc. (NASDAQ: CSTL) is set to release its financial results for the third quarter and nine months ended Sept. 30, 2021, after market close on Nov. 8, 2021. Management will hold a conference call and webcast at 4:30 p.m. Eastern time to discuss these results. The company focuses on innovative diagnostics aimed at improving disease management and patient outcomes, particularly in skin cancer diagnostics.

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Castle Biosciences (Nasdaq: CSTL) has announced recent presentations at the 2021 Fall Clinical Dermatology Conference, showcasing advancements in dermatologic cancer gene expression profile (GEP) tests and a pipeline initiative for inflammatory skin conditions. The company demonstrated the capabilities of its DecisionDx-Melanoma test, which provides personalized risk predictions for melanoma patients. Additionally, Castle is developing a GEP test to guide therapy selection for moderate to severe psoriasis and atopic dermatitis, addressing a significant unmet clinical need.

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Castle Biosciences, Inc. (CSTL) has announced the acquisition of Cernostics, Inc., enhancing its growth strategy with the TissueCypher® platform aimed at improving the diagnosis of esophageal cancer. This acquisition is expected to expand Castle's U.S. total addressable market by approximately $1 billion. The deal includes an initial payment of $30 million, with potential milestone payments of up to $50 million based on 2022 performance. The acquisition aligns with Castle's mission to utilize innovative technology for better patient outcomes in gastrointestinal diagnostics.

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Castle Biosciences (NASDAQ: CSTL) announced that CEO Derek Maetzold will keynote the AZAdvances Life Science Innovation Showcase on October 6, 2021, during Arizona Bioscience Week, occurring from October 3-9. The event, presented by AZBio and the Arizona Commerce Authority, celebrates the state's bioscience industry and its commitment to patient care and innovation. Maetzold expressed pride in supporting future innovators through AZAdvances, which provides mentorship and funding.

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Castle Biosciences (Nasdaq: CSTL) has secured approval from the New York State Department of Health for its DecisionDx® DiffDx™-Melanoma gene expression profile test. This test aims to aid dermatopathologists in diagnosing ambiguous melanocytic lesions. The approval expands the company's diagnostic offerings, which include myPath® Melanoma, enhancing the accuracy of melanoma management. Castle has previously received state approvals for other genomic tests, indicating a robust position in the dermatologic diagnostics market.

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FAQ

What is the current stock price of Castle Biosciences (CSTL)?

The current stock price of Castle Biosciences (CSTL) is $25.75 as of March 23, 2026.

What is the market cap of Castle Biosciences (CSTL)?

The market cap of Castle Biosciences (CSTL) is approximately 743.3M.

CSTL Rankings

CSTL Stock Data

743.28M
28.39M
Diagnostics & Research
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