Welcome to our dedicated page for Cyclacel Phar Pr news (Ticker: CYCCP), a resource for investors and traders seeking the latest updates and insights on Cyclacel Phar Pr stock.
Cyclacel Pharmaceuticals Inc. (CYCCP) is a clinical-stage biopharmaceutical company advancing novel cancer therapies through targeted cell cycle inhibition. This news hub provides investors and researchers with timely updates on the company’s progress in developing CDK and PLK inhibitors for oncology applications.
Access consolidated updates on clinical trial milestones, regulatory developments, and strategic partnerships. Our curated feed includes essential announcements regarding:
• Phase 1/2 clinical trial results for fadraciclib and plogosertib
• Regulatory submissions and FDA communications
• Intellectual property developments and patent grants
• Research collaborations with academic institutions
Bookmark this page for direct access to primary source materials and analysis-neutral reporting on Cyclacel’s progress in precision oncology. Check regularly for updates on the company’s efforts to address unmet needs in solid tumors and hematologic malignancies through cell cycle-targeted therapies.
Cyclacel Pharmaceuticals announced preclinical data for fadraciclib, a CDK2/9 inhibitor, demonstrating efficacy in metastatic colorectal cancer (CRC) models. Presented at the 2024 ASCO Annual Meeting, the study showed that fadraciclib significantly inhibited tumor growth, induced apoptosis, and triggered anaphase catastrophe in CRC patient-derived organoids (PDOs) and xenografts (PDXs). The research highlighted fadraciclib's superiority over standard chemotherapy and palbociclib in CRC models. Cyclacel's CEO, Spiro Rombotis, emphasized fadraciclib’s broad potential in multiple tumor types. Initial proof of concept data is expected in the second half of 2024.
Cyclacel Pharmaceuticals presented new clinical data on their CDK2/9 inhibitor, fadraciclib, at the 2024 ASCO Annual Meeting. The Phase 1 study, CYC065-101, involved heavily pretreated patients with various cancers, demonstrating clinical benefits in endometrial, lung, ovarian, pancreatic cancers, and T-cell lymphoma. Fadraciclib showed good tolerance with the most common adverse events being nausea, vomiting, and diarrhea. Pharmacokinetic (PK) and pharmacodynamic (PD) data indicated dose proportionality and efficacy in CDKN2A/B suppression. The Phase 2 proof of concept part is currently enrolling patients with CDKN2A/B loss or T-cell lymphoma, with initial results expected in the second half of 2024.
Cyclacel Pharmaceuticals (NASDAQ: CYCC) reported its first quarter 2024 financial results and provided a business update. Key highlights include enrolling patients in the Phase 2 proof-of-concept (PoC) study of oral fadraciclib, a CDK2/9 inhibitor, with data to be presented at the ASCO Annual Meeting. The company received $8.0 million from a private placement, bolstering its balance sheet. As of March 31, 2024, Cyclacel had $9.9 million in pro forma cash and cash equivalents, including $0.8 million from the UK R&D tax credit. The net loss for Q1 2024 was $2.9 million, a decrease from $5.8 million in Q1 2023. R&D expenses were $2.8 million compared to $5.7 million last year. The company plans to report key data from its ongoing clinical trials later this year.
Cyclacel Pharmaceuticals, Inc. will release its first quarter 2024 financial results on May 14, 2024. The company focuses on developing innovative cancer treatments and will host a conference call and webcast to discuss the results.
Cyclacel Pharmaceuticals, a biopharmaceutical company, closed an $8.0 million private placement under NASDAQ rules, offering shares of common stock, series A warrants, and short-term series B warrants. The gross proceeds were $8.0 million, with H.C. Wainwright & Co. as the exclusive placement agent. The company plans to use the net proceeds for working capital and general corporate purposes.
Cyclacel Pharmaceuticals, Inc. announced an $8.0 million private placement under Nasdaq rules, offering shares of common stock and warrants to purchase more shares at a fixed price. The placement is expected to close on May 2, 2024, with H.C. Wainwright & Co. acting as the exclusive placement agent. The company plans to use the net proceeds for working capital and general corporate purposes.
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