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Cypherpunk Technologies Reports First Quarter 2026 Financial Results

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(Moderate)
Rhea-AI Sentiment
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Cypherpunk Technologies (Nasdaq: CYPH) reported a Q1 2026 net loss of $77.2 million, largely driven by a $77.6 million unrealized loss as Zcash (ZEC) fell from $508.09 to $240.47.

The company increased its Zcash treasury to 314,185.70 ZEC (about 1.88% of circulating supply) and invested $5 million in Zcash Open Development Labs. Subsidiary Leap Therapeutics reported positive Phase 2 DeFianCe colorectal cancer data and received FDA Fast Track designation for sirexatamab.

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AI-generated analysis. Not financial advice.

Positive

  • Zcash treasury expanded to 314,185.70 ZEC, about 1.88% of circulating supply
  • $5 million strategic investment in Zcash Open Development Labs in March 2026
  • FDA Fast Track designation for sirexatamab in DKK1-high metastatic colorectal cancer
  • DeFianCe DKK1-high subgroup ORR 42% vs 16% control, p=0.003
  • DeFianCe DKK1-high subgroup OS hazard ratio 0.47, p=0.0244
  • Launch of new website and investor dashboard providing visibility into ZEC and other metrics

Negative

  • Q1 2026 net loss widened to $77.2 million from $15.4 million in Q1 2025
  • Unrealized loss of $77.6 million on ZEC holdings as price declined in Q1 2026
  • ZEC price dropped from $508.09 to $240.47 during Q1 2026
  • General and administrative expenses rose to $4.7 million from $3.0 million year over year
  • Cash and cash equivalents at March 31, 2026 totaled $6.7 million

News Market Reaction – CYPH

+15.38%
28 alerts
+15.38% News Effect
+17.6% Peak in 3 hr 37 min
+$17M Valuation Impact
$124.05M Market Cap
1.0x Rel. Volume

On the day this news was published, CYPH gained 15.38%, reflecting a significant positive market reaction. Argus tracked a peak move of +17.6% during that session. Our momentum scanner triggered 28 alerts that day, indicating elevated trading interest and price volatility. This price movement added approximately $17M to the company's valuation, bringing the market cap to $124.05M at that time.

Data tracked by StockTitan Argus on the day of publication.

Key Figures

Net loss Q1 2026: $77.2 million Unrealized ZEC loss: $77.6 million Cash: $6.7 million +5 more
8 metrics
Net loss Q1 2026 $77.2 million First quarter 2026, vs. $15.4 million in Q1 2025
Unrealized ZEC loss $77.6 million Change in fair value of ZEC holdings in Q1 2026
Cash $6.7 million Cash and cash equivalents at March 31, 2026
ZEC holdings value $73.8 million ZEC treasury at March 31, 2026, priced at $240.47 per ZEC
ZEC price move $508.09 to $240.47 ZEC price decline during Q1 2026
DKK1-high subgroup size 87 patients Part B DeFianCe study, DKK1-high colorectal cancer subgroup
ORR improvement 42% vs. 16% (p=0.003) Sirexatamab arm vs control in DKK1-high subgroup
OS benefit signal HR 0.47, p=0.0244 mOS not reached vs 14.39 months in control arm

Market Reality Check

Price: $1.2000 Vol: Volume 3,899,598 vs 20-da...
normal vol
$1.2000 Last Close
Volume Volume 3,899,598 vs 20-day average 3,738,940 (relative volume 1.04). normal
Technical At $1.04, shares trade slightly above the $1.02 200-day MA but 71.89% below the 52-week high.

Peers on Argus

No peers in the provided dataset show momentum flags or same-day headlines, poin...

No peers in the provided dataset show momentum flags or same-day headlines, pointing to company-specific drivers tied to ZEC exposure and Q1 results.

Previous Earnings Reports

1 past event · Latest: Mar 16 (Positive)
Same Type Pattern 1 events
Date Event Sentiment Move Catalyst
Mar 16 Full-year earnings Positive +12.6% Full-year 2025 results with large unrealized ZEC gains and net income return.
Pattern Detected

The prior earnings release with positive ZEC-driven gains coincided with a double-digit positive price move, suggesting earnings tied to ZEC marks have been a key catalyst.

Recent Company History

In March 2026, Cypherpunk’s full-year 2025 results highlighted a strategic shift into ZEC and privacy assets, including a $58.88 million private placement and 294,743.10 ZEC (~1.78% of supply) at $335.89. A $5 million ZODL investment and a $50.4 million unrealized ZEC gain drove a return to $4.8 million net income, with ZEC holdings valued at $147.4 million. Today’s Q1 2026 results continue this ZEC-centric strategy but show the opposite effect when ZEC prices decline.

Historical Comparison

+12.6% avg move · Past earnings (FY 2025) linked strong ZEC gains to a 12.6% positive move. Q1 2026 flips this, with a...
earnings
+12.6%
Average Historical Move earnings

Past earnings (FY 2025) linked strong ZEC gains to a 12.6% positive move. Q1 2026 flips this, with a large ZEC-driven unrealized loss replacing prior gains.

Earnings have shifted from FY 2025 profitability driven by a $50.4M unrealized ZEC gain to Q1 2026 results dominated by a $77.6M unrealized ZEC loss as prices fell.

Market Pulse Summary

The stock surged +15.4% in the session following this news. A strong positive reaction aligns with h...
Analysis

The stock surged +15.4% in the session following this news. A strong positive reaction aligns with how prior earnings linked ZEC performance to share moves; the last earnings event saw a 12.6% gain on ZEC-driven profits. Here, investors would be weighing a large Q1 net loss of $77.2M, driven by a $77.6M unrealized ZEC markdown, against sizable ZEC treasury value of $73.8M and encouraging sirexatamab Fast Track status and Phase 2 efficacy data.

Key Terms

zero-knowledge proofs, fast track designation, overall response rate, overall survival, +4 more
8 terms
zero-knowledge proofs technical
"Zcash uses a cryptographic method called "zero-knowledge proofs" to allow users..."
A zero-knowledge proof is a mathematical technique that lets one party prove to another that a statement is true without revealing the underlying data or secrets. Think of it like showing you have the keys to a safe without opening it: investors care because this can protect sensitive information, enable private but verifiable transactions, and improve scalability and regulatory compliance in digital finance, all of which affect risk, value, and adoption of technologies.
fast track designation regulatory
"sirexatamab received Fast Track designation from the FDA in May 2026."
A "fast track designation" is a process that speeds up the review and approval of a product or project, allowing it to reach the market or be completed more quickly than usual. For investors, it can signal that a product may become available sooner, potentially leading to earlier revenue or benefits, and indicating a priority status that might influence company performance and market opportunities.
overall response rate medical
"Sirexatamab demonstrated a statistically significant benefit on overall response rate ("ORR")..."
Overall response rate is the percentage of patients in a clinical study whose measurable disease shrinks or disappears after receiving a treatment. Investors watch it like a product’s “hit rate” because higher response rates can signal a drug’s effectiveness, boost chances of regulatory approval and market demand, and affect a company’s future revenue prospects, similar to how a higher batting average suggests a more reliable player.
overall survival medical
"Sirexatamab demonstrated a statistically significant benefit on... overall survival ("OS")..."
Overall survival is the average or median length of time patients remain alive after starting a treatment or entering a clinical study, measured regardless of cause of death. Investors care because it is a clear, hard measure of a therapy’s real-world benefit — like timing how long a new battery actually runs — and strong improvements in overall survival can drive regulatory approval, market adoption and revenue potential.
p-value medical
"ORR was 42%... vs. 16% ORR in the Control Arm, p-value = 0.003."
A p-value is a number that helps determine how likely it is that a result or pattern happened by chance rather than because of a real effect. For investors, a low p-value suggests that the findings in a study or analysis are probably meaningful and not just random noise—like noticing a pattern in coin flips that’s unlikely to occur by chance. This helps in assessing the reliability of information used to make financial decisions.
hazard ratio medical
"mOS was not reached... vs. 14.39 months in the Control Arm, HR 0.47, p-value = 0.0244."
A hazard ratio is a way scientists compare the chance of something happening over time between two groups, like patients taking different medicines. If the ratio is high, it means one group is more likely to experience the event sooner or more often, which helps determine how effective a treatment is or how risky a situation might be.
monoclonal antibody medical
"sirexatamab, the Company's anti-DKK1 monoclonal antibody."
A monoclonal antibody is a laboratory-made protein designed to recognize and attach to a specific target in the body, such as a disease-causing substance or cell. It functions like a highly precise lock-and-key tool, helping to treat or detect illnesses. For investors, companies developing monoclonal antibodies can represent promising opportunities in the healthcare sector, especially as these treatments often address unmet medical needs.
companion diagnostic medical
"a new plasma DKK1 biomarker assay that could be used as a companion diagnostic..."
A companion diagnostic is a medical test designed to identify which patients are likely to benefit from a specific drug or medical treatment, much like a key that shows whether a particular lock will open. For investors, these tests matter because they can increase a drug’s chances of approval and market uptake, create a separate revenue stream, and reduce commercial risk by matching treatments to the patients most likely to respond.

AI-generated analysis. Not financial advice.

CAMBRIDGE, Mass., May 14, 2026 /PRNewswire/ -- Cypherpunk Technologies Inc., (Nasdaq: CYPH) ("Cypherpunk"), today reported financial results for the first quarter ended March 31, 2026.

"Since the start of 2026, Cypherpunk has advanced the mission to become a leading privacy technology company with a digital asset treasury strategy focused on Zcash by making our first privacy technology investment and increasing our treasury holdings to 314,185.70 ZEC," said Douglas E. Onsi, President and CEO of Cypherpunk Technologies. "At AACR 2026, our Leap Therapeutics subsidiary presented a new DKK1 biomarker assay developed to support the selection of patients likely to benefit from sirexatamab therapy, along with the positive outcomes from our DeFianCe colorectal cancer study generated in patients with high DKK1 levels. In addition, sirexatamab received Fast Track designation from the FDA in May 2026."

"Privacy-protecting assets and related technologies will be critical in the increasingly digital and AI driven world. Our $5 million investment in Zcash Open Development Labs (ZODL), the core developers of the Zcash Network and Zodl, the leading Zcash wallet, reflects our commitment to supporting the Zcash ecosystem and to building innovative companies that make the promise of private digital money a reality," said Will McEvoy, Chief Investment Officer of Cypherpunk.

Cypherpunk Highlights:

  • Increased Zcash treasury holdings to 314,185.70 ZEC
    • From the last update on April 15, 2026 through May 13, 2026, Cypherpunk purchased an additional 10,279.30 ZEC for $5 million at an average purchase price of $486.41 per ZEC.
    • As of May 13, 2026, Cypherpunk held a total of 314,185.70 ZEC at an average purchase price of $337.86, representing approximately 1.88% of the total circulating supply of the Zcash network.
    • ZEC is a digital currency that can be transmitted over a peer-to-peer payment system. Zcash uses a cryptographic method called "zero-knowledge proofs" to allow users to engage in financial transactions while maintaining greater privacy.
  • Invested $5 million into Zcash Open Development Labs (ZODL)
    • In March 2026, Cypherpunk expanded its holdings with a $5 million investment in ZODL, alongside key investors including a16z, Winklevoss Capital, Coinbase, Paradigm, Chapter One, David Friedberg, Balaji Srinivasan, and others. This marked Cypherpunk's first technology investment outside of ZEC. ZODL, which houses the top Zcash wallet, Zodl, aims to make Zcash easier to use with continued development of the wallet and support of the Zcash protocol.
  • Launched new website and investor dashboard at cypherpunk.com
    • The Company launched its new website and investor dashboard at cypherpunk.com. The dashboard provides shareholders with direct visibility into the Company's key metrics, ZEC holdings, other privacy investments, and Zcash network metrics.

Leap Therapeutics Subsidiary Highlights:

  • Sirexatamab received Fast Track designation from FDA
    • In May 2026, the U.S. Food and Drug Administration (FDA) granted Fast Track designation to sirexatmab in combination with fluoropyrimidine plus oxaliplatin- or irinotecan-based chemotherapy and bevacizumab, for the treatment of patients with DKK1-high metastatic colorectal cancer whose disease has progressed following one prior systemic therapy.
    • The Fast Track program is intended to facilitate the development and expedite the review of drug candidates and vaccines that treat serious conditions and fill an unmet medical need. Programs with Fast Track designation may benefit from frequent communication with the FDA, in addition to a rolling submission of the marketing application.
  • Presented new plasma DKK1 biomarker assay and results based on Part B of the DeFianCe study of sirexatamab plus bevacizumab and chemotherapy in colorectal cancer ("CRC") patients at the American Association for Cancer Research (AACR) 2026:
    • At AACR 2026 in April, the Company presented a new plasma DKK1 biomarker assay that could be used as a companion diagnostic to select patients who would benefit from treatment with sirexatamab, the Company's anti-DKK1 monoclonal antibody.
    • The new plasma DKK1 biomarker assay was used to test the patient samples from Part B of the DeFianCe study, a Phase 2 study of sirexatamab in combination with bevacizumab and chemotherapy compared to bevacizumab and chemotherapy in patients with microsatellite stable CRC who have received one prior systemic therapy for advanced disease.
    • Sirexatamab demonstrated a statistically significant benefit on overall response rate ("ORR") and overall survival ("OS") in patients with high levels of DKK1 using the new plasma DKK1 biomarker assay.
    • 50% of patients had DKK1-high levels > 380 pg/ml, and in this subgroup of patients (n=87):
      • ORR was 42% (including one complete response) in the Sirexatamab Arm vs. 16% ORR in the Control Arm, p-value = 0.003.
      • mOS was not reached in the Sirexatamab Arm vs. 14.39 months in the Control Arm, HR 0.47, p-value = 0.0244.
    • DKK1 plasma levels from patients in the DeFianCe study were similar to commercially acquired CRC patient samples.

Selected First Quarter 2026 Financial Results

Net loss was $77.2 million for the first quarter 2026, compared to $15.4 million for the first quarter of 2025. The increase was primarily due to unrealized losses on the fair value of the Company's ZEC treasury holdings which are marked to market at the end of each period. During the first quarter of 2026, the price of ZEC declined from $508.09 to $240.47.

Research and development expenses were $0.2 million for the three months ended March 31, 2026, compared to $12.9 million for the same period in 2025. The decrease for the three months ended March 31, 2026 was primarily due to a decrease in clinical trial costs and manufacturing costs due to the completion of our clinical trials.

General and administrative expenses were $4.7 million for the three months ended March 31, 2026, compared to $3.0 million for the same period in 2025. The increase for the three months ended March 31, 2026 was primarily due to an increase in stock-based compensation expense due to RSUs granted to employees and directors.

During the three months ended March 31, 2026, the Company recorded a $77.6 million unrealized loss on the change in fair value of the Company's ZEC treasury holdings as the price of ZEC declined during the first quarter of 2026 from $508.09 to $240.47.

Cash and cash equivalents totaled $6.7 million on March 31, 2026, and ZEC treasury holdings, categorized as digital asset receivable, totaled $73.8 million based on the ZEC price of $240.47 on March 31, 2026.

About Cypherpunk

Cypherpunk Technologies is a privacy technology company. The Company's mission is to advance technologies that guarantee privacy for humans on the internet. Cypherpunk pursues this mission through two primary strategies: accumulating Zcash (ZEC); and investing in, acquiring, and building technologies that push the frontier of privacy forward. Additionally, through its subsidiary Leap Therapeutics, the Company is developing novel therapies for patients with cancer, continuing the development of sirexatamab and FL-501. For more information about the Company, visit our websites at http://www.cypherpunk.com and http://www.leaptx.com or view our public filings with the SEC that are available via EDGAR at http://www.sec.gov.

About Winklevoss Capital

Winklevoss Capital is an investment firm founded in 2012 by Cameron and Tyler Winklevoss that invests in frontier technologies.

FORWARD-LOOKING STATEMENTS

This press release includes forward-looking statements within the meaning of Section 27A of the Securities Act of 1933, as amended, Section 21E of the Securities Exchange Act of 1934, as amended. These forward-looking statements generally can be identified by the use of words such as "anticipate," "expect," "plan," "could," "may," "will," "believe," "estimate," "forecast," "goal," "project," and other words of similar meaning. Forward-looking statements address various matters including statements relating to the value of the Company's ZEC holdings, the investment in ZODL, or digital assets held or to be held by the Company, the expected future market, price, and liquidity of ZEC or other digital assets the Company acquires, the macro and political conditions surrounding Zcash or digital assets, the Company's plan for value creation and strategic advantages, market size and growth opportunities, regulatory conditions, competitive position and the interest of other corporations in similar business strategies, technological and market trends, and future financial condition and performance. Risks and uncertainties of the digital asset treasury strategy include, among others: (a) risks relating to the Company's operations and business, including the highly volatile nature of the price of ZEC; (b) the risk that material changes in the price of ZEC, such as decreases in price, will result in significant changes to the Company's financial statements, such as unrealized losses on fair value of ZEC holdings and net loss; (c) the risk that the price of the Company's Common Stock may be highly correlated to the price of ZEC; (d) the risk that the Company will fail to realize the anticipated benefits of the ZEC digital asset treasury strategy or the investment in ZODL; (e) risks related to the custody of our ZEC and our reliance on Gemini Space Station and its affiliates for trading and custody services; (f) changes in business, market, financial, political and regulatory conditions; (g) risks related to increased competition in the industries in which the Company does and will operate; (h) risks relating to significant legal, commercial, regulatory and technical uncertainty regarding digital assets generally; (i) risks relating to the treatment of crypto assets for U.S. and foreign tax purposes; and (j) the ability to comply with the continued listing requirements of the Nasdaq Capital Market. With respect to our biotechnology operations, important factors that could cause actual results to differ materially from our plans, estimates or expectations could include, but are not limited to: (i) our ability and plan to develop and commercialize sirexatamab; (ii) our estimates regarding our capital requirements and our ability to raise additional financing to support continued development; (iii) the success of other competing therapies that may become available; (iv) the manufacturing capacity for sirexatmab; and (v) our ability to maintain and protect our intellectual property rights.

New risks and uncertainties may emerge from time to time, and it is not possible to predict all risks and uncertainties. No representations or warranties (expressed or implied) are made about the accuracy of any such forward-looking statements. The Company may not actually achieve the forecasts disclosed in such forward-looking statements, and you should not place undue reliance on such forward-looking statements. Such forward-looking statements are subject to a number of material risks and uncertainties including but not limited to those set forth under the caption "Risk Factors" in the Company's most recent Annual Report on Form 10-K filed with the SEC, or as may be included in other reports or information we file with the SEC, as well as discussions of potential risks, uncertainties, and other important factors in its subsequent filings with the SEC. Any forward-looking statement speaks only as of the date on which it was made. Neither the Company, nor any of its affiliates, advisors or representatives, undertake any obligation to publicly update or revise any forward-looking statement, whether as a result of new information, future events or otherwise, except as required by law. These forward-looking statements should not be relied upon as representing the Company's views as of any date subsequent to the date hereof.

Cypherpunk Technologies Inc.

Consolidated Balance Sheets

(in thousands, except share and per share amounts)




















March 31, 


December 31, 









2026


2025









(Unaudited)














Assets








Current assets:






Cash and cash equivalents


$           6,689


$         14,035


Digital assets receivable


73,849


147,404


Research and development incentive receivable


616


602


Prepaid expenses and other current assets


768


40






Total current assets


81,922


162,081













Right of use assets, net


38


38


Deferred costs


385


401


Deposits



33


662


Other investment


5,000


-






Total assets


$         87,378


$        163,182

Liabilities and Stockholders' Equity 





Current liabilities:






Accounts payable


$              516


$           1,981


Accrued expenses


1,966


2,067


Income tax payable


483


472


Lease liability 


38


38






Total current liabilities


3,003


4,558












Non-current liabilities:






Deferred tax liability


-


5,118






Total liabilities


3,003


9,676












Stockholders' equity:






Preferred stock, $0.001 par value; 10,000,000 shares authorized; 0 shares issued
    and outstanding as of March 31, 2026 and December 31, 2025, respectively


-


-


Common stock, $0.001 par value; 490,000,000 shares authorized; 93,927,528 and 83,851,051
    shares issued and outstanding as of March 31, 2026 and December 31, 2025, respectively


94


84


Stock subscription receivable


-


(150)


Additional paid-in capital


624,082


616,216


Accumulated other comprehensive loss


(86)


(95)


Accumulated deficit 


(539,715)


(462,549)






Total stockholders' equity 


84,375


153,506






Total liabilities and stockholders' equity 


$         87,378


$        163,182

Cypherpunk Technologies Inc.

Consolidated Statements of Operations

(in thousands, except share and per share amounts)




















(Unaudited)









Three Months Ended March 31









2026


2025












Operating expenses:






Research and development


$                  161


$             12,911


General and administrative 


4,656


3,006




    Total operating expenses


4,817


15,917

Loss from operations


(4,817)


(15,917)

Interest income 


95


437

Interest expense


(7)


(6)

Australian research and development incentives


-


55

Change in fair value of embedded derivative


(77,555)


-

Foreign currency loss


-


(4)

Loss before income taxes


(82,284)


(15,435)

Benefit from income taxes


5,118


-

Net loss attributable to common stockholders


$            (77,166)


$            (15,435)












Net loss per share 








Basic and Diluted


$               (0.46)


$               (0.37)












Weighted average common shares outstanding 








Basic and diluted


168,103,535


41,268,894

 Cypherpunk Technologies Inc. 

 Condensed Consolidated Statements of Cash Flows 

 (in thousands) 




















 (Unaudited) 









 Three Months Ended March 31, 









2026


2025










 Cash used in operating activities 


$                (3,430)


$               (14,480)

 Cash used in investing activities 


(9,000)


-

 Cash provided by (used in) financing activities 


5,075


(61)

 Effect of exchange rate changes on cash and cash equivalents 


9


5

 Net decrease in cash and cash equivalents 


(7,346)


(14,536)

 Cash and cash equivalents at beginning of period 


14,035


47,249

 Cash and cash equivalents at end of period 


$                  6,689


$                32,713

CONTACT:
Douglas E. Onsi
President & Chief Executive Officer
Cypherpunk Technologies Inc.
617-714-0360

For Investors:

Matthew DeYoung
Investor Relations
Argot Partners
212-600-1902
leap@argotpartners.com

For Media:

Jacqueline Ortiz Ramsey
It Factor Strategies
954-294-3249
jacqueline@itfactorstrategies.com

Cypherpunk Technologies Inc. Logo (PRNewsfoto/Leap Therapeutics, Inc.)

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/cypherpunk-technologies-reports-first-quarter-2026-financial-results-302771640.html

SOURCE Cypherpunk Technologies Inc.

FAQ

What were Cypherpunk (Nasdaq: CYPH) Q1 2026 financial results?

Cypherpunk reported a Q1 2026 net loss of $77.2 million. According to Cypherpunk, the loss was mainly driven by a $77.6 million unrealized loss on ZEC holdings, with cash of $6.7 million and ZEC treasury valued at $73.8 million on March 31, 2026.

How large are Cypherpunk's Zcash (ZEC) holdings as of May 13, 2026?

Cypherpunk held 314,185.70 ZEC as of May 13, 2026. According to Cypherpunk, this represents about 1.88% of Zcash’s circulating supply, at an average purchase price of $337.86 per ZEC, after buying 10,279.30 ZEC for $5 million at $486.41 each.

What is Cypherpunk's $5 million investment in Zcash Open Development Labs (ZODL)?

Cypherpunk invested $5 million in ZODL in March 2026. According to Cypherpunk, ZODL develops the Zcash protocol and the Zodl wallet, aiming to make Zcash easier to use and marking Cypherpunk’s first technology investment outside of directly holding ZEC.

What FDA Fast Track designation did sirexatamab receive in May 2026?

Sirexatamab received FDA Fast Track designation in May 2026. According to Cypherpunk, it covers sirexatamab plus chemotherapy and bevacizumab for DKK1-high metastatic colorectal cancer after one prior systemic therapy, enabling more frequent FDA interactions and rolling review of a marketing application.

What were the DeFianCe study results for sirexatamab in DKK1-high colorectal cancer?

In DKK1-high patients, sirexatamab improved response and survival versus control. According to Cypherpunk, ORR was 42% vs 16% (p=0.003), and median overall survival was not reached vs 14.39 months (HR 0.47; p=0.0244) in 87 patients with DKK1 levels above 380 pg/ml.

How did Zcash price movements affect Cypherpunk's Q1 2026 results?

A sharp Zcash price decline drove a large unrealized loss for Cypherpunk. According to Cypherpunk, ZEC fell from $508.09 to $240.47 during Q1 2026, leading to a $77.6 million unrealized loss on ZEC treasury holdings and contributing to the $77.2 million net loss.