STOCK TITAN

Notifications

Limited Time Offer! Get Platinum at the Gold price until January 31, 2026!

Sign up now and unlock all premium features at an incredible discount.

Read more on the Pricing page

Cryoport Reports Third Quarter 2025 Financial Results

Rhea-AI Impact
(Moderate)
Rhea-AI Sentiment
(Neutral)
Tags

Cryoport (NASDAQ: CYRX) reported Q3 2025 revenue of $44.2M, up 15% year‑over‑year, and raised full‑year continuing operations revenue guidance to $170.0–$174.0M. Commercial cell & gene therapy revenue grew 36% to $8.3M; Life Sciences Services revenue rose 16% and Life Sciences Products revenue rose 15% in Q3. Gross margin improved to 48.2% in Q3. Adjusted EBITDA from continuing operations narrowed to a $0.6M loss in Q3. Cryoport held $421.3M cash and completed share repurchases of 483,397 shares for $3.7M. The company noted strategic moves including a new Paris Global Supply Chain Center, MVE product launches, and a DHL partnership.

Cryoport (NASDAQ: CYRX) ha riportato ricavi del terzo trimestre 2025 pari a $44.2M, in aumento del 15% rispetto all'anno precedente, e ha alzato le previsioni annuali dei ricavi da operazioni continue a $170.0–$174.0M. I ricavi da terapie cellulari e geniche commerciali sono cresciuti del 36% a $8.3M; i ricavi dei Life Sciences Services sono saliti del 16% e i ricavi dei Life Sciences Products sono aumentati del 15% nel Q3. Il margine lordo è migliorato al 48.2% nel Q3. L'EBITDA rettificato da operazioni continue è diminuito a una perdita di $0.6M nel trimestre. Cryoport contava $421.3M di cassa e ha completato i riacquisti di azioni per 483.397 azioni per $3.7M. L'azienda ha segnalato mosse strategiche tra cui un nuovo Global Supply Chain Center a Parigi, lanci di prodotti MVE e una partnership con DHL.

Cryoport (NASDAQ: CYRX) informó ingresos del 3T 2025 de $44.2M, un 15% más año tras año, y elevó las previsiones de ingresos para el año completo de operaciones continuas a $170.0–$174.0M. Los ingresos de terapias celulares y génicas comerciales crecieron un 36% hasta $8.3M; los ingresos de Life Sciences Services subieron un 16% y Life Sciences Products subieron 15% en el 3T. El margen bruto mejoró al 48.2% en el 3T. El EBITDA ajustado de las operaciones continuas se redujo a una pérdida de $0.6M en el 3T. Cryoport contaba con $421.3M en efectivo y completó recompras de 483,397 acciones por $3.7M. La empresa señaló movimientos estratégicos, como un nuevo Global Supply Chain Center en París, lanzamientos de productos MVE y una asociación con DHL.

Cryoport (NASDAQ: CYRX)가 2025년 3분기 매출 $44.2M를 보고했으며 전년 동기 대비 15% 증가했고, 계속 영업 매출 가이던스를 $170.0–$174.0M으로 상향했습니다. 상업용 세포 및 유전자 치료 매출은 36% 증가하여 $8.3M에 이르렀고; Life Sciences Services 매출은 16% 상승, Life Sciences Products 매출은 3분기에 15% 증가했습니다. 3분기 총이익률은 48.2%로 개선되었습니다. 계속 영업에서의 조정 EBITDA는 3분기에 $0.6M 손실로 축소되었습니다. Cryoport는 현금 $421.3M를 보유하고 있으며 483,397주를 $3.7M에 재매입했습니다. 회사는 파리의 새로운 Global Supply Chain Center, MVE 제품 출시, DHL 파트너십 등 전략적 움직임을 언급했습니다.

Cryoport (NASDAQ: CYRX) a annoncé un chiffre d'affaires du 3e trimestre 2025 de $44.2M, en hausse de 15% sur un an, et a relevé les prévisions de chiffre d'affaires annuels des activités opérationnelles continues à $170.0–$174.0M. Les revenus des thérapies cellulaires et géniques commerciales ont augmenté de 36% pour atteindre $8.3M; les revenus Life Sciences Services ont augmenté de 16% et les revenus Life Sciences Products ont progressé de 15% au T3. La marge brute s'est améliorée à 48.2% au T3. L'EBITDA ajusté des activités continues s'est réduit à une perte de $0.6M au T3. Cryoport disposait de $421.3M de liquidités et a mené des rachats d'actions de 483 397 actions pour $3.7M. L'entreprise a évoqué des évolutions stratégiques, dont un nouveau Global Supply Chain Center à Paris, des lancements de produits MVE et un partenariat avec DHL.

Cryoport (NASDAQ: CYRX) meldete für das Q3 2025 einen Umsatz von $44.2M, ein Anstieg von 15% gegenüber dem Vorjahr, und hob die Umsatzprognose für das Gesamtjahr der fortgeführten Geschäftsaktivitäten auf $170.0–$174.0M an. Der Umsatz aus kommerziellen Zell- & Gentherapie-Aktivitäten wuchs um 36% auf $8.3M; der Umsatz aus Life Sciences Services stieg um 16% und der Umsatz aus Life Sciences Products stieg im Q3 um 15%. Die Bruttomarge verbesserte sich im Q3 auf 48.2%. Das bereinigte EBITDA aus fortgeführten Aktivitäten verringerte sich im Q3 auf einen Verlust von $0.6M. Cryoport verfügte über $421.3M an Bargeld und hat den Rückkauf von 483.397 Aktien für $3.7M abgeschlossen. Das Unternehmen verwies auf strategische Schritte, darunter ein neues Global Supply Chain Center in Paris, Veröffentlichungen von MVE-Produkten und eine DHL-Partnerschaft.

Cryoport (NASDAQ: CYRX) أبلغت عن إيرادات الربع الثالث 2025 بقيمة $44.2M، بزيادة 15% على أساس سنوي، ورفعت توجيهات الإيرادات للسنة كاملة من عمليات مستمرة إلى $170.0–$174.0M. ارتفعت إيرادات العلاجات الخلوية والجينية التجارية بنسبة 36% لتصل إلى $8.3M؛ وارتفعت إيرادات خدمات العلوم الحياتية بنسبة 16% وارتفعت إيرادات منتجات العلوم الحياتية بنسبة 15% في الربع الثالث. تحسن الهامش الإجمالي إلى 48.2% في الربع الثالث. تقلص EBITDA المعدلة من العمليات المستمرة إلى خسارة قدرها $0.6M في الربع الثالث. بلغت لدى Cryoport نقداً قدره $421.3M وأتمت إعادة شراء أسهم لـ 483,397 سهماً بقيمة $3.7M. أشارت الشركة إلى تحركات استراتيجية بما في ذلك مركز سلسلة الإمداد العالمي الجديد في باريس، وإطلاقات منتجات MVE، وشراكة مع DHL.

Positive
  • Total revenue +15% YoY to $44.2M in Q3 2025
  • Commercial cell & gene revenue +36% YoY to $8.3M
  • Gross margin improved to 48.2% in Q3 2025
  • Raised FY2025 continuing operations guidance to $170.0–$174.0M
  • Cash, cash equivalents, and short‑term investments of $421.3M
Negative
  • Q3 2025 net loss of $6.9M
  • Adjusted EBITDA still negative at $0.6M loss in Q3 2025
  • 9M 2025 net income driven by one‑time CRYOPDP sale of $115.4M
  • Guidance exposed to U.S. federal government shutdown and macro risks

Insights

Cryoport shows broad revenue growth, margin expansion, stronger cash and raised 2025 guidance, signaling improving operational performance.

Cryoport reported Q3 revenue of $44.2 million, a 15% year‑over‑year increase, with Life Sciences Services at $24.3 million (+16%) and Life Sciences Products at $20.0 million (+15%). Commercial cell & gene therapy support rose 36% to $8.3 million, BioStorage/BioServices grew 21%, and management raised full‑year 2025 revenue guidance to $170.0$174.0 million. Gross margin improved to 48.2% in Q3 and adjusted EBITDA from continuing operations narrowed to a negative $0.6 million versus negative $2.7 million a year earlier.

These facts describe a company moving toward profitability while investing in growth: improved margins, narrower adjusted EBITDA losses, significant cash and equivalents of $421.3 million, and an active share repurchase of ~483k shares for $3.7 million. Key dependencies and risks are explicit: the company cites the ongoing U.S. federal government shutdown as a potential adverse factor and notes guidance depends on macro, supply chain, and foreign exchange items. Watchables over the near term include delivery against the raised 2025 revenue range, the impact of the DHL partnership on EMEA/APAC Life Sciences Services growth, execution of the Paris and planned Santa Ana Global Supply Chain Centers, and upcoming customer regulatory milestones (up to 7 filings and 1 new therapy approval expected in the remainder of 2025, and multiple PDUFA dates in early 2026), all of which could materially affect revenue recognition and service demand within the next 6–12 months.

  • Third quarter revenue increased 15% year-over-year to $44.2 million
  • Commercial Cell & Gene Therapy revenue increased 36% year-over-year to $8.3 million
  • Life Sciences Services revenue grew 16% year-over-year, including a 21% rise in BioStorage/BioServices revenue
  • Life Sciences Products revenue grew 15% year-over-year
  • Company updates full year 2025 revenue guidance of $170 to $174 million

NASHVILLE, Tenn., Nov. 4, 2025 /PRNewswire/ -- Cryoport, Inc. (NASDAQ: CYRX) ("Cryoport" or the "Company"), a leading global provider of temperature-controlled supply chain solutions for the life sciences, today announced financial results for its third quarter (Q3) and first nine months (9M) of 2025. Provided in this press release are financial performance highlights, an update to our annual revenue guidance for 2025 and access information for today's earnings conference call.

Jerrell Shelton, CEO of Cryoport, commented, "Q3 was another outstanding quarter for Cryoport with 15% year-over-year growth in revenue from continuing operations. During the third quarter, we continued to see strong momentum, with double-digit growth. A driver of our total Q3 revenue was from the support of commercial cell and gene therapies, which grew 36% year-over-year to $8.3 million. Our Q3 Life Sciences Services revenue increased 16% year-over-year, representing 55% of total revenue from continuing operations. This included a 21% rise in BioStorage/BioServices revenue, reflecting continued strong demand for our integrated platform. We also saw encouraging signs of stability in our Life Sciences Products segment, where revenue grew 15% year-over-year, supported by sustained demand for our market-leading cryogenic systems. Cryoport continues to demonstrate a visible pathway to profitability with improvements in adjusted EBITDA and a solid gross margin of 48% in Q3, while continuing to invest in our priority growth initiatives to drive long-term value.

"We also executed on key strategic and operational initiatives during the quarter. MVE Biological Solutions launched its next-generation SC 4/2V and SC 4/3V dry vapor shippers equipped with integrated Condition Monitoring Solutions for these dewars, combining its trusted cryogenic systems with our advanced, real-time condition monitoring technology supplied by Tec4med, another Cryoport company. Our pipeline of new innovative products and services, including IntegriCell, positions Cryoport well to capture greater wallet share and offer clients a more integrated solution.

"We also expanded our global infrastructure with the opening of our newest Global Supply Chain Center near the Charles de Gaulle Airport in Paris, France, while advancing plans to open another Global Supply Chain Center in Santa Ana, California targeted for late 2026 that will replace three existing facilities in the area. In addition, we have begun leveraging our recently established strategic partnership with the DHL Group, which we anticipate, as it develops, will fuel growth in our Life Sciences Services business in EMEA and APAC and further strengthen our leadership in supporting the global life sciences market. 

"With our momentum and year-to-date performance along with our strong Q3 results, we are raising our full-year revenue guidance from continuing operations to a range of $170.0 million to $174.0 million. Cryoport continues to maintain competitive differentiation as the only pure-play end-to-end temperature-controlled supply chain platform that supports the largest portfolio of clinical and commercial Cell & Gene therapies," concluded Mr. Shelton.

In tabular form, Q3 2025 and 9M 2025 revenue compared to Q3 2024 and 9M 2024, respectively, were as follows:

Cryoport, Inc. and Subsidiaries







Revenue 







(unaudited)








Three Months Ended
September 30,

Nine Months Ended
September 30,

(in thousands)

2025

2024

% Change

2025

2024

% Change

Life Sciences Services

$            24,258

$            20,931

16 %

$            71,492

$            60,568

18 %

BioLogistics Solutions

19,428

16,955

15 %

57,832

49,540

17 %

BioStorage/BioServices 

4,830

3,976

21 %

13,660

11,028

24 %

Life Sciences Products

$            19,975

$            17,386

15 %

$            59,235

$            54,749

8 %

Total Revenue From Continuing Operations

$            44,233

$            38,317

15 %

$          130,727

$          115,317

13 %

BioStorage/BioServices revenue continued to experience strong year-over-year growth, increasing 21% in Q3 2025 as we continue to introduce our capabilities to existing clients, add new clients into our global network, and as more commercial therapies progress in the number of patients treated.

Revenue from the support of commercial cell & gene therapies increased 36% year-over-year to $8.3 million and included revenue from BioLogistics Solutions and sale of accessories. As of September 30, 2025, we supported nineteen (19) commercial therapies.

As of September 30, 2025, Cryoport supported a total of 745 global clinical trials, a net increase of 54 clinical trials over September 30, 2024, with 83 of these clinical trials in Phase 3. The number of trials by phase and region are as follows: 

Cryoport Supported Clinical Trials by Phase

Clinical Trials

September 30,

2023

2024

2025

Phase 1

275

295

309

Phase 2

314

317

353

Phase 3

81

79

83

Total

670

691

745





Cryoport Supported Clinical Trials by Region

Clinical Trials

September 30,

2023

2024

2025

Americas

516

531

559

EMEA

112

112

137

APAC

42

48

49

Total

670

691

745

In Q3 2025, 4 Biologics License Applications (BLA) / Marketing Authorization Applications (MAA) filings occurred. Post quarter-end, 3 additional BLA filings occurred. During the quarter, Cryoport's customer ExCellThera received conditional marketing authorization from the European Commission (EC) for their cell therapy Zemcelpro®, as the first and only cell therapy for blood cancer patients without access to suitable donor cells. This EC decision authorizes the marketing of Zemcelpro® in all European Union member states, as well as Iceland, Norway and Liechtenstein.

Recently and subsequent to the end of Q3 2025, Cryoport's customer Bristol Myers Squibb received another supplemental approval from the EC to expand the label of Breyanzi® as a third line treatment for relapsed or refractory follicular lymphoma. During the remainder of 2025, we anticipate up to an additional 7 application filings, 1 new therapy approval and an additional 2 approvals for label/geographic expansions; however, these anticipated approvals and filings may be adversely impacted by the current federal government shutdown in the United States.

Looking ahead to 2026, 5 customers have Prescription Drug User Fee Act (PDUFA) dates in the first and very early second quarter. Additionally, we are currently forecasting up to 25 possible BLA/MAA filings in 2026, with the majority being for new therapies.

Operational milestones

Life Sciences Services

  • Launched our newest, state-of-the-art Global Supply Chain Center at Charles de Gaulle airport in Paris, France, with another Global Supply Chain Center in Santa Ana, California targeted for late 2026.
  • IntegriCell, with cryopreservation service centers located near Liège, Belgium and in Houston, Texas, made further progress in onboarding our first clients, with technology transfer activities nearing completion for multiple biotechnology and top 10 pharmaceutical companies.

Life Sciences Products

  • MVE Biological Solutions (MVE) launched its next generation SC 4/2V and SC 4/3V dry vapor shippers, offering improved safety and reliability for transporting and preserving sensitive biological materials at cryogenic temperatures.
  • Unveiled MVE's integrated Condition Monitoring Solutions for its SC 4/2V and 4/3V dry vapor shippers, combining MVE's trusted cryogenic systems with advanced, real-time condition monitoring technology supplied by Tec4med, a Cryoport company.

Financial Highlights

On June 11, 2025, the Company completed its previously announced divestiture of its specialty courier CRYOPDP business to DHL Supply Chain International Holding B.V. ("DHL") and entered into a strategic partnership with DHL. The divestiture and strategic partnership are expected to enhance the Company's ability to develop its business, particularly in the EMEA and APAC regions, and to provide differentiated and high-value services aligned with Cryoport's long-term growth strategy. The results of CRYOPDP, a former business within Cryoport's Life Sciences Services segment, are presented as discontinued operations for all periods presented within the Condensed Consolidated Statements of Operations and Condensed Consolidated Balance Sheets included in this press release and are also not included in the non-GAAP financial measures presented herein.

Revenue

  • Total revenue from continuing operations for Q3 2025 was $44.2 million compared to $38.3 million for Q3 2024, a year-over-year increase of 15% or $5.9 million.
    • Life Sciences Services revenue for Q3 2025 (representing 55% of our total revenue from continuing operations) was $24.3 million compared to $20.9 million for Q3 2024, up 16% year-over-year, including BioStorage/BioServices revenue of $4.8 million, up 21% year-over-year.
    • Life Sciences Products revenue for Q3 2025 (representing 45% of our total revenue from continuing operations) was $20.0 million compared to $17.4 million for Q3 2024, up 15% year-over-year.
  • Total revenue from continuing operations for 9M 2025 was $130.7 million compared to $115.3 million for 9M 2024.
    • Life Sciences Services revenue for 9M 2025 was $71.5 million compared to $60.6 million for 9M 2024, including BioStorage/BioServices revenue of $13.7 million for 9M 2025 compared to $11.0 million for 9M 2024.
    • Life Sciences Products revenue for 9M 2025 was $59.2 million compared to $54.7 million for 9M 2024.

Gross Margin

  • Total gross margin from continuing operations was 48.2% for Q3 2025 compared to 45.5% for Q3 2024.
    • Gross margin for Life Sciences Services was 49.7% for Q3 2025 compared to 48.3% for Q3 2024. 
    • Gross margin for Life Sciences Products was 46.4% for Q3 2025 compared to 42.1% for Q3 2024.
  • Total gross margin from continuing operations was 46.9% for 9M 2025 compared to 43.5% for 9M 2024.
    • Gross margin for Life Sciences Services was 48.8% for 9M 2025 compared to 46.2% for 9M 2024. 
    • Gross margin for Life Sciences Products was 44.6% for 9M 2025 compared to 40.5% for 9M 2024.

Operating Costs and Expenses

  • Operating costs and expenses from continuing operations were $31.3 million for Q3 2025 compared to $30.8 million for Q3 2024. Operating costs and expenses for 9M 2025 decreased to $88.1 million compared to $159.1 million for 9M 2024. The decrease for 9M 2025 reflects an impairment charge of $63.8 million in Q2 2024, which was primarily related to the write off of remaining goodwill for MVE. Excluding the impairment charge, adjusted operating costs and expenses for 9M 2025 were $88.1 million, compared to $95.3 million for 9M 2024.

Net Income (Loss) – including Discontinued Operations

  • Net loss for Q3 2025 was $6.9 million and net income for 9M 2025 was $89.9 million, compared to net income of $0.8 million and a net loss of $96.1 million for the same periods in 2024, respectively. Net income for 9M 2025 was primarily driven by the sale of our CRYOPDP specialty courier business during Q2 2025, which contributed $115.4 million, net of taxes, to income from discontinued operations.
  • Net loss attributable to common stockholders for Q3 2025 was $8.9 million, or $0.18 per share. Net income attributable to common stockholders for 9M 2025 was $83.9 million, or $1.68 per share. This compares to net losses attributable to common stockholders of $1.2 million, or $0.02 per share, and $102.1 million, or $2.07 per share, for Q3 2024 and 9M 2024, respectively.
  • Non GAAP adjusted net loss was $25.4 million for 9M 2025, compared to $50.8 million for 9M 2024.

Adjusted EBITDA from continuing operations

  • Adjusted EBITDA from continuing operations was a negative $0.6 million for Q3 2025, compared to a negative $2.7 million for Q3 2024. Adjusted EBITDA from continuing operations for 9M 2025 was a negative $ 4.4 million compared to a negative $14.9 million for 9M 2024.

Cash, Cash equivalents, and Short-Term Investments

  • Cryoport held $421.3 million in cash, cash equivalents, and short-term investments as of September 30, 2025.

Share Repurchase Programs

  • During Q3 2025, the Company purchased 483,397 shares of its common stock under its repurchase programs, at an average price of $7.73 per share, for an aggregate amount of $3.7 million. These shares were returned to the status of authorized but unissued shares of common stock. Following these repurchases, the Company had approximately $65.9 million in total repurchase authorization available under its two repurchase programs.

Updated Guidance for Continuing Operations for Full-Year Fiscal 2025

  • The Company now expects total revenue from continuing operations for fiscal year 2025 to be in the range of $170.0 million to $174.0 million. The Company's 2025 guidance is dependent on its current business and expectations, which may be further impacted by, among other things, factors that are outside of our control, such as national economic factors, the global macroeconomic and geopolitical environment, supply chain constraints, inflationary pressures, the continued U.S. federal government shutdown, tariffs and other trade restrictions and/or the effects of foreign currency fluctuations, as well as the other factors described in the Company's filings with the Securities and Exchange Commission ("SEC"), including in the "Risk Factors" section of its most recently filed periodic reports on Form 10-K and Form 10-Q, as well as in its subsequent filings with the SEC.

Note: All reconciliations of GAAP to adjusted (non-GAAP) figures above are detailed in the reconciliation tables included later in the press release.

Additional Information

Further information on Cryoport's financial results is included in the attached condensed consolidated balance sheets and statements of operations, and additional explanations of Cryoport's financial performance are provided in the Company's Quarterly Report on Form 10-Q for the three months ended September 30, 2025, which is expected to be filed with the SEC on November 6, 2025. Additionally, the full report will be available in the SEC Filings section of the Investor Relations section of Cryoport's website at www.cryoportinc.com.

Earnings Conference Call Information

IMPORTANT INFORMATION: In addition to the earnings release, a document titled "Cryoport Third Quarter 2025 in Review", providing a review of Cryoport's business update, will be issued at 4:05 p.m. ET on Tuesday, November 4, 2025. The document is designed to be read in advance of the questions and answers conference call and will be accessible at https://ir.cryoportinc.com/news-events/ir-calendar.

Cryoport management will host a conference call at 5:00 p.m. ET on November 4, 2025. The conference call will be in the format of a questions and answers session and will address any queries investors have regarding the Company's reported results. A slide deck will accompany the call.

Conference Call Information

Date:

Tuesday, November 4, 2025

Time:

5:00 p.m. ET

Dial-in numbers:

1-800-717-1738 (U.S.), 1-646-307-1865 (International)

Confirmation code:

Request the "Cryoport Call" or Conference ID: 1120106

Live webcast:

'Investor Relations' section at www.cryoportinc.com or click here.

 

Please allow 10 minutes prior to the call to visit this site to download and install any necessary audio software.

The questions and answers call will be recorded and available approximately three hours after completion of the live event in the Investor Relations section of the Company's website at www.cryoportinc.com for a limited time. To access the replay of the questions and answers click here. A dial-in replay of the call will also be available to those interested, until November 11, 2025. To access the replay, dial 1-844-512-2921 (United States) or 1-412-317-6671 (International) and enter replay entry code: 1120106#.

About Cryoport, Inc.

Cryoport, Inc. (Nasdaq: CYRX), is a leading global provider of temperature-controlled supply chain solutions for the life sciences, with an emphasis on regenerative medicine. We support biopharmaceutical companies, contract manufacturers (CDMOs), contract research organizations (CROs), developers, and researchers with a comprehensive suite of services and products designed to minimize risk and maximize reliability across the temperature-controlled supply chain for the life sciences. Our integrated supply chain platform includes the Cryoportal® Logistics Management Platform, advanced temperature-controlled packaging, informatics, specialized biologistics, biostorage, bioservices, cryopreservation services, and cryogenic systems, which in varying combinations deliver end-to-end solutions that meet the rigorous demands of the life sciences. With innovation, regulatory compliance, and agility at our core, we are "Enabling the Future of Medicine™." 

Headquartered in Nashville, Tennessee, our company maintains a strong global presence with operations across the Americas, EMEA, and APAC.

For more information, visit www.cryoportinc.com or follow via LinkedIn at https://www.linkedin.com/company/cryoportinc or @cryoport on X, formerly known as Twitter at https://x.com/cryoport for live updates.

Forward-Looking Statements
Statements in this press release which are not purely historical, including statements regarding the Company's intentions, hopes, beliefs, expectations, representations, projections, plans or predictions of the future, are forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995. These forward-looking statements include, but are not limited to, those related to the Company's industry, business, long-term growth prospects, plans, strategies, acquisitions, future financial results and financial condition, such as the Company's outlook and updated guidance for full-year 2025 revenue and the related assumptions and factors expected to drive revenue, projected growth trends in the markets in which the Company operates, the Company's plans and expectations regarding the launch of new products and services, such as the expected timing and benefits of such products and services launches, the Company's expectations about future benefits of its acquisitions, and anticipated regulatory filings, approvals, label/geographic expansions or moves to earlier lines of treatment approved with respect to the products of the Company's clients. Forward-looking statements also include those related to the Company's expectations about future benefits relating to the CRYOPDP divestiture and strategic partnership with DHL (collectively, the "DHL Transaction") and the Company's plans regarding the completion of its Global Supply Chain Centers, including expected timing. It is important to note that the Company's actual results could differ materially from those in any such forward-looking statements. Factors that could cause actual results to differ materially include, but are not limited to, risks and uncertainties associated with the effect of changing economic and geopolitical conditions, supply chain constraints, inflationary pressures, tariffs and other trade restrictions, the effects of foreign currency fluctuations, trends in the products markets, the continued U.S federal government shutdown, variations in the Company's cash flow, market acceptance risks, and technical development risks. Additional risks and uncertainties relating to the DHL Transaction include, but are not limited to, the risk that any disruption resulting from the DHL Transaction may adversely affect our businesses and business relationships, including with employees and suppliers. The Company's business could be affected by other factors discussed in the Company's SEC reports, including in the "Risk Factors" section of its most recently filed periodic reports on Form 10-K and Form 10-Q, as well as in its subsequent filings with the SEC. The forward-looking statements contained in this press release speak only as of the date hereof and the Company cautions investors not to place undue reliance on these forward-looking statements. Except as required by law, the Company disclaims any obligation and does not undertake to update or revise any forward-looking statements in this press release.

 

Cryoport, Inc. and Subsidiaries





Condensed Consolidated Statements of Operations






Three Months Ended
September 30,
(unaudited)

Nine Months Ended
September 30,
(unaudited)

(in thousands, except share and per share data)

2025

2024

2025

2024

Revenue





Life Sciences Services revenue

$                   24,258

$                   20,931

$                   71,492

$                   60,568

Life Sciences Products revenue

19,975

17,386

59,235

54,749

Total revenue

44,233

38,317

130,727

115,317

Cost of revenue:





Cost of services revenue

12,201

10,822

36,570

32,578

Cost of products revenue

10,707

10,059

32,814

32,576

Total cost of revenue

22,908

20,881

69,384

65,154

Gross margin

21,325

17,436

61,343

50,163

Operating costs and expenses:





Selling, general and administrative

26,734

26,668

75,543

81,725

Engineering and development

4,523

4,157

12,575

13,555

Impairment loss

-

-

-

63,809

Total operating costs and expenses:

31,257

30,825

88,118

159,089

Loss from operations

(9,932)

(13,389)

(26,775)

(108,926)

Other income (expense):





Investment income

3,402

3,059

6,441

8,468

Interest expense

(526)

(882)

(1,727)

(3,398)

Gain on extinguishment of debt, net

-

17,326

-

18,505

Other income (expense), net

525

(1,878)

(2,714)

(1,691)

Income (loss) before provision for income taxes

(6,531)

4,236

(24,775)

(87,042)

Provision for income taxes

(165)

(316)

(673)

(493)

Income (loss) from continuing operations

$                   (6,696)

$                     3,920

$                (25,448)

$                (87,535)

Income (loss) from discontinued operations, net

(247)

(3,115)

115,393

(8,544)

Net income (loss)

$                   (6,943)

$                        805

$                 89,945

$                (96,079)

Paid-in-kind dividend on Series C convertible preferred stock

(2,000)

(2,000)

(6,000)

(6,000)

Net income (loss) attributable to common stockholders

$                   (8,943)

$                   (1,195)

$                 83,945

$              (102,079)

Net income (loss) per share attributable to common stockholders:





Basic

$                     (0.18)

$                     (0.02)

$                     1.68

$                    (2.07)

Weighted average common shares issued and outstanding:





Basic

50,125,268

49,417,757

50,110,450

49,261,717

 

Cryoport, Inc. and Subsidiaries



Condensed Consolidated Balance Sheets




September 30,

December 31,


2025

2024

(in thousands)



Current assets



Cash and cash equivalents

$                     255,811

$                       34,137

Short-term investments

165,503

216,460

Accounts receivable, net

34,914

25,304

Inventories

23,326

21,476

Prepaid expenses and other current assets

5,289

7,944

Current assets held for sale

-

36,251

Total current assets

484,843

341,572

Property and equipment, net

83,233

80,013

Operating lease right-of-use assets

40,224

39,920

Intangible assets, net

141,254

147,927

Goodwill

22,409

20,569

Deposits

2,097

1,951

Deferred tax assets

268

842

Long-term assets held for sale

-

70,699

 Total assets 

$                     774,328

$                     703,493




Current liabilities



Accounts payable and other accrued expenses

$                       13,884

$                       15,895

Accrued compensation and related expenses

10,864

11,209

Deferred revenue

1,447

1,061

Current portion of operating lease liabilities

4,126

3,399

Current portion of finance lease liabilities

428

315

Current portion of convertible senior notes, net

-

14,298

Current portion of notes payable

-

143

Current portion of contingent consideration

-

2,808

Current liabilities held for sale

-

15,435

Total current liabilities

30,749

64,563

Convertible senior notes, net

184,799

183,919

Notes payable, net

1,291

1,114

Operating lease liabilities, net

39,376

38,551

Finance lease liabilities, net

840

800

Deferred tax liabilities

664

804

Other long-term liabilities

2,708

296

Contingent consideration, net

630

3,751

Long-term liabilities held for sale

-

7,797

    Total liabilities

261,057

301,595

    Total stockholders' equity

513,271

401,898

    Total liabilities and stockholders' equity

$                     774,328

$                     703,493

Note Regarding Use of Non-GAAP Financial Measures

To supplement our financial statements, which are presented on the basis of U.S. generally accepted accounting principles (GAAP), the following non-GAAP measures of financial performance as defined in Regulation G of the Securities Exchange Act of 1934 are included in this release: adjusted operating costs and expenses, adjusted net income (loss), and adjusted EBITDA from continuing operations. Non-GAAP financial measures are not calculated in accordance with GAAP, are not based on any comprehensive set of accounting rules or principles and may be different from non-GAAP financial measures presented by other companies. Non-GAAP financial measures, including adjusted operating costs and expenses, adjusted net income (loss), and adjusted EBITDA from continuing operations, should not be considered as a substitute for, or superior to, measures of financial performance prepared in accordance with GAAP.

Adjusted operating costs and expenses is defined as operating costs and expenses, excluding impairment losses, if any. Adjusted net income (loss) is defined as net income (loss), excluding impairment losses, gain on extinguishment of debt, net, and income (loss) from discontinued operations, including gain on sale, if any. Management believes these measures, when read in conjunction with, and as supplemental to, the corresponding GAAP financial measures, provide useful measures to investors of Cryoport's expenses and operating results, meaningful comparisons with historical results, and insight into Cryoport's operating performance.

Adjusted EBITDA from continuing operations is defined as income (loss) from continuing operations adjusted for net interest expense, income taxes, depreciation and amortization expense, stock-based compensation expense, acquisition and integration costs, cost reduction initiatives, investment income, unrealized (gain)/loss on investments, foreign currency (gain)/loss, net gain on extinguishment of debt, impairment loss, changes in fair value of contingent consideration and charges or gains resulting from non-recurring events, as applicable.

Management believes that adjusted EBITDA from continuing operations provides a useful measure of Cryoport's operating results, a meaningful comparison with historical results and with the results of other companies, and insight into Cryoport's ongoing operating performance. Further, management and the Company's board of directors utilize adjusted EBITDA from continuing operations to gain a better understanding of Cryoport's comparative operating performance from period to period and as a basis for planning and forecasting future periods. Adjusted EBITDA from continuing operations is also a significant performance measure used by Cryoport in connection with its incentive compensation programs. Management believes adjusted EBITDA from continuing operations, when read in conjunction with Cryoport's GAAP financials, is useful to investors because it provides a basis for meaningful period-to-period comparisons of Cryoport's ongoing operating results, including results of operations, against investor and analyst financial models, helps identify trends in Cryoport's underlying business and in performing related trend analyses, and it provides a better understanding of how management plans and measures Cryoport's underlying business.

Cryoport, Inc. and Subsidiaries





Reconciliation of GAAP operating cost and expenses to Non-GAAP adjusted operating cost and expenses







Three Months Ended
September 30,
(unaudited)

Nine Months Ended
September 30,
(unaudited)


2025

2024

2025

2024

(in thousands)





GAAP operating costs and expenses

$         31,257

$              30,825

$         88,118

$      159,089

Non-GAAP adjustments to operating costs and expenses





Impairment loss

(63,809)

Non-GAAP adjusted operating costs and expenses

$         31,257

$              30,825

$         88,118

$        95,280






Cryoport, Inc. and Subsidiaries





Reconciliation of GAAP net income (loss) to Non-GAAP adjusted net income (loss)









Three Months Ended
September 30,
(unaudited)

Nine Months Ended
September 30,
(unaudited)


2025

2024

2025

2024

(in thousands)





GAAP net income (loss)

$         (6,943)

$                 805

$         89,945

$      (96,079)

Non-GAAP adjustments to net income (loss)





Income (loss) from discontinued operations, including gain on sale

(247)

115,393

Gain on extinguishment of debt, net

17,326

18,505

Impairment loss

(63,809)

Non-GAAP adjusted net income (loss)

$         (6,696)

$           (16,521)

$       (25,448)

$      (50,775)

 

Cryoport, Inc. and Subsidiaries





Reconciliation of GAAP income (loss) from continuing operations to adjusted EBITDA


(unaudited)






Three Months Ended
September 30,

Nine Months Ended
September 30,


2025

2024

2025

2024

(in thousands)





GAAP income (loss) from continuing operations

$           (6,696)

$               3,920

$         (25,448)

$         (87,535)

Non-GAAP adjustments to income (loss):





Depreciation and amortization expense

6,415

6,041

18,798

17,573

Acquisition and integration costs

38

118

69

652

Cost reduction initiatives

160

397

642

532

Investment income

(3,402)

(3,059)

(6,441)

(8,468)

Unrealized (gain)/loss on investments

(655)

3,535

620

2,593

Foreign currency (gain)/loss

274

(1,621)

2,521

(778)

Interest expense, net

526

882

1,727

3,398

Stock-based compensation expense

2,526

4,056

7,635

12,923

Gain on extinguishment of debt, net

(17,326)

(18,505)

Impairment loss

63,809

Change in fair value of contingent consideration

43

(5,178)

(1,602)

Income taxes

165

316

673

493

Adjusted EBITDA from continuing operations

$              (649)

$            (2,698)

$           (4,382)

$         (14,915)

 

 

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/cryoport-reports-third-quarter-2025-financial-results-302604558.html

SOURCE Cryoport, Inc.

FAQ

What were Cryoport (CYRX) Q3 2025 total revenues and YoY growth?

Cryoport reported Q3 2025 total revenue of $44.2M, a 15% year‑over‑year increase.

How much did Cryoport's commercial cell & gene therapy revenue (CYRX) grow in Q3 2025?

Commercial cell & gene therapy revenue grew 36% YoY to $8.3M in Q3 2025.

What FY2025 revenue guidance did Cryoport (CYRX) update on Nov 4, 2025?

Cryoport raised full‑year continuing operations revenue guidance to $170.0M–$174.0M for 2025.

What was Cryoport's gross margin and adjusted EBITDA in Q3 2025?

Q3 2025 gross margin was 48.2%; adjusted EBITDA from continuing operations was a $0.6M loss.

How much cash did Cryoport (CYRX) hold as of September 30, 2025?

Cryoport held $421.3M in cash, cash equivalents, and short‑term investments as of September 30, 2025.

Did Cryoport (CYRX) complete any share repurchases in Q3 2025 and for how much?

Yes; Cryoport repurchased 483,397 shares for an aggregate $3.7M in Q3 2025.

What operational expansions did Cryoport (CYRX) announce in Q3 2025?

Cryoport opened a Global Supply Chain Center near Paris CDG, launched MVE dry vapor shippers, and advanced a DHL partnership.
Cryoport Inc

NASDAQ:CYRX

CYRX Rankings

CYRX Latest News

CYRX Latest SEC Filings

CYRX Stock Data

452.61M
47.31M
3.82%
100.71%
5.44%
Integrated Freight & Logistics
Pharmaceutical Preparations
Link
United States
BRENTWOOD