Welcome to our dedicated page for Altamira Therapeutics news (Ticker: CYTO), a resource for investors and traders seeking the latest updates and insights on Altamira Therapeutics stock.
Altamira Therapeutics Ltd. (historically Nasdaq: CYTO) generates news primarily around its RNA delivery platforms, legacy therapeutic assets, and capital markets activity. Company announcements describe ongoing development of its peptide-based nanoparticle technologies OligoPhore and SemaPhore for efficient RNA delivery to extrahepatic tissues, along with preclinical progress in its flagship siRNA programs AM-401 for KRAS-driven cancer and AM-411 for rheumatoid arthritis.
News items frequently cover business updates and financial results, where Altamira outlines its strategic repositioning around RNA delivery, reports on research milestones, and discusses collaborations with biotech and pharma partners. Press releases have highlighted independent preclinical publications using its SemaPhore platform in oncology and inflammatory disease models, as well as internal advances in nanoparticle formulation and process development.
Altamira-related news also includes developments from its associated company Altamira Medica AG and the commercial-stage nasal spray Bentrio. Announcements have detailed license and distribution agreements for Bentrio in regions such as East and South East Asia and Scandinavia, expansion of partner territories, and clinical data supporting its use in allergic rhinitis and protection against airborne particles. Additional releases have addressed topics like Bentrio’s suitability for athletes based on analytical testing for substances on the World Anti-Doping Agency list.
Capital markets and listing updates form another important category of news. The company has issued releases on public offerings of common shares and warrants, use of proceeds for working capital and research, and its transition from the Nasdaq Capital Market to the OTCQB marketplace following a Nasdaq delisting decision related to the minimum bid price rule. Investors following CYTO can use this news stream to monitor scientific progress, partnering activity, commercialization steps for Bentrio, and changes in trading venue or financing transactions.
Altamira Therapeutics (NASDAQ:CYTO) announced that animal study data presented at the American Heart Association Annual Scientific Sessions 2022 demonstrated effective delivery of SOD2 mRNA using its SemaPhore technology. The research showed significant improvements in mitochondrial protection and plaque stability in atherosclerosis models. Following treatment, mice exhibited a 25% reduction in inflammatory macrophages and a 98% increase in smooth muscle cells, indicating less plaque vulnerability. This highlights the potential of nanoparticle-based mRNA therapeutics in addressing atherosclerosis complications.
Altamira Therapeutics Ltd. (NASDAQ:CYTO) announced its participation in the TIDES Europe event from November 16-18, 2022, in Vienna, Austria. Covadonga Pañeda, Ph.D., Chief Development Officer, will present on the benefits of the OligoPhoreTM / SemaPhoreTM RNA delivery technology and discuss two proprietary RNA programs: AM-401 for KRAS-driven cancers and AM-411 for rheumatoid arthritis. Altamira aims to become a leader in RNA delivery technology through partnerships and out-licensing its platforms and programs.
Altamira Therapeutics Ltd. (NASDAQ: CYTO) announced on November 8, 2022, that it has regained compliance with Nasdaq listing requirements. The company received confirmation that its share price had been at or above $1.00 for ten consecutive business days, thus meeting the Minimum Bid Price Requirement. This marks a significant milestone for Altamira, ensuring its continued listing on the Nasdaq exchange while it focuses on advancing its pipeline of therapeutics targeting unmet medical needs.
Altamira Therapeutics Ltd. (NASDAQ: CYTO) announced the publication of a peer-reviewed study in the International Archives of Allergy and Immunology on Bentrio, a drug-free nasal spray for allergic rhinitis. The study demonstrated Bentrio's rapid onset of action and superior efficacy compared to a marketed HPMC spray, with participants rating it twice as favorable. With FDA clearance obtained in June 2022, Bentrio is currently distributed in Europe and Asia, and plans for divestiture in North America and Europe are in progress.
Altamira Therapeutics Ltd. (NASDAQ:CYTO) announced a 1-for-20 reverse stock split, effective October 25, 2022, to meet NASDAQ's $1.00 minimum bid price requirement. This action will consolidate every 20 shares into one, reducing the total shares outstanding from approximately 21.5 million to about 1.1 million. The reverse split will not affect the percentage ownership or voting rights of shareholders. The authorized common shares will decrease to 5 million, with a new par value of CHF 0.20 per share, while fractional shares will be compensated in cash.
Altamira Therapeutics (NASDAQ:CYTO) has entered a definitive agreement to sell a 90% stake in its subsidiary Zilentin, focusing on inner ear therapeutics. The deal includes an immediate cash payment of $2 million and potential future payments totaling $55 million. Zilentin will acquire the option to purchase remaining inner ear assets for $25 million cash. This transaction aligns with Altamira's strategy to concentrate solely on RNA delivery technology. CEO Thomas Meyer will oversee Zilentin while continuing at Altamira, which is also working to divest its Bentrio nasal spray by year-end.
Altamira Therapeutics (Nasdaq: CYTO) will participate in the RNA Leaders USA Congress on October 18-19, 2022, in Boston, MA. Chief Scientific Officer Samuel Wickline, MD, will present their OligoPhore/SemaPhore delivery platform, emphasizing its advantages for siRNA therapeutics. Key benefits include a universal formulation process, extrahepatic delivery with minimal off-target effects, and deep tissue penetration. Altamira aims to out-license this innovative platform to biotech firms and is developing internal programs targeting KRAS-driven cancers and rheumatoid arthritis.
Altamira Therapeutics (NASDAQ:CYTO) has resumed participant enrollment in its NASAR clinical trial for the Bentrio nasal spray aimed at treating seasonal allergic rhinitis in Australia, coinciding with the onset of pollen season. The study will include 100 patients and compare the safety and efficacy of Bentrio against a saline nasal spray, with data results expected by Q1 2023. The trial, initially started in fall 2021, faced a temporary suspension in spring 2022. Interim data previously assisted in obtaining FDA clearance for Bentrio.
Altamira Therapeutics Ltd. (NASDAQ:CYTO) announces the re-launch of its Bentrio nasal spray in selected European countries, starting in Germany in early October 2022. The product aims to alleviate allergic symptoms from airborne allergens like pollen and dust mites. Bentrio's protective effects have been supported by clinical trials. The company is also engaged in partnership discussions for distribution in Europe and the US, expected to conclude by Q4 2022. Additionally, interim data from ongoing clinical studies may support further labeling expansions.
Altamira Therapeutics (NASDAQ:CYTO) announced it has reached its extended enrollment target of 160 patients in the COVAMID clinical trial, which evaluates the efficacy of Bentrio™ nasal spray for acute COVID-19 treatment. Top-line data is anticipated in Q4-2022. Bentrio, a drug-free nasal spray, is designed to protect against airborne viruses and allergens and has recently received OTC marketing clearance in the US for allergic rhinitis. A successful trial outcome could expand its product label to include viral infections.