Welcome to our dedicated page for Altamira Therapeutics news (Ticker: CYTO), a resource for investors and traders seeking the latest updates and insights on Altamira Therapeutics stock.
Altamira Therapeutics Ltd. reports developments around peptide-based nanoparticle technologies for RNA delivery to extrahepatic tissues. Company updates focus on the OligoPhore™ and SemaPhore™ platforms, preclinical siRNA programs including AM-401 for KRAS-driven cancer and AM-411 for rheumatoid arthritis, and the use of the delivery technology across RNA modalities.
Recurring news also covers Bentrio® nasal spray licensing and distribution through Altamira Medica, financing transactions involving common shares and warrants, interim financial results, business-update calls, and the company’s completed transition from Nasdaq trading to the OTCQB market under the CYTOF ticker.
Altamira Therapeutics (NASDAQ:CYTO) will hold an investor call on September 14, 2022, at 10:30 a.m. ET, to discuss its strategy in RNA therapeutics. Investors can access the call via a toll-free number or international number. The webcast starts 15 minutes prior, and questions can be submitted via email by September 11, 2022. A replay will be available 30 minutes post-call until September 28, 2022. Altamira focuses on RNA therapeutics, nasal sprays for allergens, and treatments for tinnitus and hearing loss.
Altamira Therapeutics (NASDAQ:CYTO) will participate in the 4th Annual RAS-Targeted Drug Development Summit from September 26-28, 2022, in Boston. Chief Scientific Officer Samuel Wickline, MD, will present on the OligoPhore platform for targeting KRAS-driven cancers. The summit aims to unite over 300 experts focused on therapeutic advancements for RAS-mutant cancers. Altamira has two RNA-based programs: AM-401 for KRAS-driven cancers and AM-411 for rheumatoid arthritis, emphasizing a unique approach that enhances delivery of RNA therapeutics to cancer cells.
Altamira Therapeutics (NASDAQ:CYTO) is shifting its focus to RNA therapeutics while planning to divest or spin off its legacy assets, including Bentrio and AM-125 nasal sprays. In H1 2022, Bentrio generated $1.3 million in revenue. The company aims to commercialize Bentrio globally through partnerships, with significant interest in the U.S. and European markets. Altamira is also moving forward with AM-125's development and preparing for an IND filing by Q4 2022. The company is making strides in RNA delivery technology, with promising results in preclinical studies.
Altamira Therapeutics (NASDAQ:CYTO) is transforming its business by focusing on RNA therapeutics, addressing unmet medical needs. CEO Thomas Meyer highlighted the company's strategy to out-license projects in oncology and rheumatoid arthritis, leveraging its patented RNA delivery technology. Plans for divesting legacy programs are underway, with milestones expected to drive growth. The company aims to establish itself as a pure RNA therapeutics player, enhancing its market position through innovative solutions.
Altamira Therapeutics (NASDAQ:CYTO) announces the continuation of enrollment in the COVAMID trial, increasing the participant count from 136 to 160 to enhance statistical power. The top-line results are anticipated by early Q4-22. The trial evaluates the efficacy of Bentrio, a drug-free nasal spray for COVID-19, in a randomized placebo-controlled study. Bentrio aims for label expansion into viral infections in key markets including the US and EU. The interim analysis indicated a higher standard deviation than expected, prompting the increase in subjects for rigorous efficacy testing.
Altamira Therapeutics (NASDAQ:CYTO) announced a peer-reviewed study confirming its OligoPhore delivery platform's potential in RNA treatments for osteoarthritis. Conducted by a Shanghai-based group, the study demonstrated that knockdown of the JMJD3 gene using OligoPhore significantly mitigated joint degeneration in an animal model. This innovative therapy targets inflammation specifically in the joints, offering a promising approach to treat osteoarthritis, which currently lacks disease-modifying treatments. The research emphasizes the role of OligoPhore in enhancing RNA therapeutic efficacy.
Altamira Therapeutics (NASDAQ:CYTO) has launched a new drug development program, AM-411, targeting rheumatoid arthritis (RA) utilizing its proprietary OligoPhore delivery platform. This initiative follows encouraging animal study results and aims to out-license AM-411 in the future. RA affects approximately 1.3 million adults in the US and is projected to be a $62.9 billion market by 2027. AM-411 demonstrated effective inflammation suppression in preclinical models, focusing on the NF-κB pathway, which is crucial in RA. The company also plans to advance its other project, AM-401, for KRAS-driven cancers.
Altamira Therapeutics (NASDAQ: CYTO) announced a peer-reviewed study published in Pharmaceutics that demonstrates the potential of cell-penetrating peptides (CPPs) in mRNA-based cancer therapies. The study highlighted the superior uptake and transfection capacity of Altamira's SemaPhore platform compared to cationic CPPs. The results indicate that SemaPhore-mRNA complexes enhance protein expression within cancer cells, showcasing an advantage over traditional lipid-based nanoparticles. Dr. Samuel Wickline emphasized SemaPhore's ability for effective systemic delivery to extrahepatic targets, relevant for various therapeutic areas.
Altamira Therapeutics (NASDAQ:CYTO) announced the publication of a peer-reviewed article in Biomaterials Advances that showcases the effectiveness of its patented RNA delivery platform in mitigating abdominal aortic aneurysm (AAA) progression and rupture in a murine model. The study, conducted independently by researchers at Washington University, identified NF-κB p50 as a key target for drug design. With AAA leading to approximately 15,000 deaths annually in the U.S., the findings highlight the potential of Altamira's OligoPhore platform as a non-surgical treatment for this severe condition.
Altamira Therapeutics (NASDAQ:CYTO) has announced the signing of marketing and distribution agreements for its Bentrio™ nasal spray in Pakistan and Egypt. Partnering with deKhon Global in Pakistan and Vie Pharma in Egypt, the company taps into significant markets with populations of 242 million and 106 million, respectively. These agreements expand Bentrio's global reach beyond Europe, Asia, and the Middle East, enhancing its distribution network. Bentrio is a drug-free product aimed at providing protection against airborne viruses and allergens, already cleared for allergic rhinitis treatment in the US.