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Dynavax Reports Second Quarter 2025 Financial Results

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Dynavax (NASDAQ:DVAX) reported strong Q2 2025 financial results, highlighted by record HEPLISAV-B quarterly net product revenue of $92 million, representing 31% year-over-year growth. The company refined its full-year 2025 HEPLISAV-B revenue guidance to $315-325 million.

Total Q2 revenues reached $95.4 million, with GAAP net income of $18.7 million ($0.16 per share). HEPLISAV-B's U.S. market share increased to 45%, up from 42% in Q2 2024. The company expects the U.S. hepatitis B vaccine market to expand to over $900 million in annual sales by 2030.

Key pipeline updates include anticipated top-line results from Phase 1/2 shingles vaccine trial in August 2025 and completed dosing in Part 1 of the pandemic influenza adjuvant program trial.

Dynavax (NASDAQ:DVAX) ha riportato risultati finanziari solidi per il secondo trimestre del 2025, con un record di ricavi netti trimestrali del prodotto HEPLISAV-B pari a 92 milioni di dollari, che rappresentano una crescita del 31% rispetto allo stesso periodo dell'anno precedente. L'azienda ha rivisto la stima dei ricavi per HEPLISAV-B per l'intero 2025, prevedendo un intervallo di 315-325 milioni di dollari.

I ricavi totali del secondo trimestre hanno raggiunto 95,4 milioni di dollari, con un utile netto GAAP di 18,7 milioni di dollari (0,16 dollari per azione). La quota di mercato di HEPLISAV-B negli Stati Uniti è salita al 45%, rispetto al 42% nel secondo trimestre del 2024. L'azienda prevede che il mercato statunitense del vaccino per l'epatite B supererà i 900 milioni di dollari di vendite annue entro il 2030.

Tra gli aggiornamenti chiave della pipeline, sono attesi i risultati preliminari dello studio di Fase 1/2 sul vaccino per l'herpes zoster ad agosto 2025, mentre è stata completata la somministrazione nella Parte 1 dello studio sul programma di adiuvante per l'influenza pandemica.

Dynavax (NASDAQ:DVAX) reportó sólidos resultados financieros en el segundo trimestre de 2025, destacando un récord de ingresos netos trimestrales del producto HEPLISAV-B de 92 millones de dólares, lo que representa un crecimiento interanual del 31%. La compañía ajustó su pronóstico de ingresos para todo el año 2025 de HEPLISAV-B a 315-325 millones de dólares.

Los ingresos totales del segundo trimestre alcanzaron 95,4 millones de dólares, con un ingreso neto GAAP de 18,7 millones de dólares (0,16 dólares por acción). La cuota de mercado de HEPLISAV-B en EE.UU. aumentó al 45%, desde el 42% en el segundo trimestre de 2024. La empresa espera que el mercado estadounidense de vacunas contra la hepatitis B crezca a más de 900 millones de dólares en ventas anuales para 2030.

Entre las actualizaciones clave de la cartera, se esperan resultados preliminares del ensayo de fase 1/2 para la vacuna contra el herpes zóster en agosto de 2025 y se completó la dosificación en la Parte 1 del ensayo del programa de adyuvante para la influenza pandémica.

Dynavax (NASDAQ:DVAX)는 2025년 2분기 강력한 재무 실적을 보고했으며, 분기별 HEPLISAV-B 순제품 매출 9,200만 달러로 사상 최고치를 기록하며 전년 동기 대비 31% 성장했습니다. 회사는 2025년 전체 HEPLISAV-B 매출 가이던스를 3억 1,500만~3억 2,500만 달러로 조정했습니다.

2분기 총 매출은 9,540만 달러에 달했으며, GAAP 순이익은 1,870만 달러(주당 0.16달러)였습니다. HEPLISAV-B의 미국 시장 점유율은 2024년 2분기 42%에서 45%로 상승했습니다. 회사는 미국 B형 간염 백신 시장이 2030년까지 연간 매출 9억 달러 이상으로 성장할 것으로 예상합니다.

주요 파이프라인 업데이트로는 2025년 8월 대상포진 백신 1/2상 임상시험의 초기 결과 발표 예정과 팬데믹 인플루엔자 보조제 프로그램 시험 1부 용량 투여 완료가 포함됩니다.

Dynavax (NASDAQ:DVAX) a annoncé de solides résultats financiers pour le deuxième trimestre 2025, avec un record de 92 millions de dollars de revenus nets trimestriels du produit HEPLISAV-B, soit une croissance de 31 % par rapport à l'année précédente. La société a affiné ses prévisions de revenus annuels pour HEPLISAV-B à 315-325 millions de dollars.

Les revenus totaux du deuxième trimestre ont atteint 95,4 millions de dollars, avec un bénéfice net GAAP de 18,7 millions de dollars (0,16 dollar par action). La part de marché américaine de HEPLISAV-B est passée à 45 %, contre 42 % au deuxième trimestre 2024. La société prévoit que le marché américain du vaccin contre l'hépatite B dépassera 900 millions de dollars de ventes annuelles d'ici 2030.

Parmi les mises à jour clés du pipeline, on attend les résultats préliminaires de l'essai de phase 1/2 du vaccin contre le zona en août 2025, ainsi que la fin du dosage dans la première partie de l'essai du programme d'adjuvant pour la grippe pandémique.

Dynavax (NASDAQ:DVAX) meldete starke Finanzergebnisse für das zweite Quartal 2025, mit einem Rekord von HEPLISAV-B Nettoproduktumsatz im Quartal von 92 Millionen US-Dollar, was einem Wachstum von 31 % im Jahresvergleich entspricht. Das Unternehmen hat seine Umsatzprognose für HEPLISAV-B im Gesamtjahr 2025 auf 315-325 Millionen US-Dollar angepasst.

Die Gesamterlöse im zweiten Quartal betrugen 95,4 Millionen US-Dollar, mit einem GAAP-Nettogewinn von 18,7 Millionen US-Dollar (0,16 US-Dollar pro Aktie). Der Marktanteil von HEPLISAV-B in den USA stieg auf 45 %, gegenüber 42 % im zweiten Quartal 2024. Das Unternehmen erwartet, dass der US-Markt für Hepatitis-B-Impfstoffe bis 2030 auf über 900 Millionen US-Dollar Jahresumsatz anwachsen wird.

Zu den wichtigsten Pipeline-Updates gehören erwartete Zwischenergebnisse der Phase-1/2-Studie zum Gürtelrose-Impfstoff im August 2025 sowie der Abschluss der Dosierung im Teil 1 der Studie zum Pandemie-Grippe-Adjuvans-Programm.

Positive
  • Record HEPLISAV-B quarterly revenue of $91.9M, up 31% YoY
  • Market share increased to 45% from 42% YoY
  • Strong cash position of $613.7M as of June 30, 2025
  • GAAP net income increased to $18.7M from $11.4M YoY
  • Completed $200M share repurchase program
  • Raised lower end of full-year revenue guidance to $315-325M
Negative
  • Cash position decreased from $713.8M to $613.7M since December 2024
  • SG&A expenses increased 21% to $50.4M compared to Q2 2024
  • R&D expenses rose to $16.6M from $15.0M YoY

Insights

Dynavax delivered record HEPLISAV-B revenue, raised guidance, and advances promising pipeline with critical data expected soon.

Dynavax reported impressive Q2 2025 results, with HEPLISAV-B achieving record quarterly revenue of $91.9 million, representing 31% year-over-year growth compared to $70.2 million in Q2 2024. This robust performance led management to raise the lower end of their full-year HEPLISAV-B revenue guidance to $315-$325 million from the previous $305-$325 million.

The company's financial health remains strong, with $613.7 million in cash and investments, despite completing its $200 million share repurchase program. Profitability metrics show significant improvement, with GAAP net income reaching $18.7 million ($0.16 per share basic), up from $11.4 million ($0.09 per share) in Q2 2024. Adjusted EBITDA nearly doubled to $37.3 million from $20.5 million in the prior-year quarter.

HEPLISAV-B continues gaining market share, now at approximately 45% of the U.S. adult hepatitis B vaccine market, up from 42% a year ago. Management projects the market will expand to over $900 million in annual sales by 2030, with HEPLISAV-B capturing at least 60% market share. This forecast suggests significant revenue growth potential for the company's lead product.

Beyond HEPLISAV-B, Dynavax's pipeline is advancing with several promising vaccine candidates leveraging their CpG 1018 adjuvant technology. Most notably, the company expects to release top-line results from Part 1 of its Phase 1/2 shingles vaccine trial in August 2025, potentially positioning them to compete in what management describes as a "multi-billion-dollar shingles vaccine market." The plague vaccine program secured $30 million in Department of Defense funding through 2027, while the pandemic influenza and Lyme disease programs continue to progress.

Overall operating expenses increased year-over-year, with R&D expenses rising to $16.6 million from $15.0 million and SG&A expenses increasing to $50.4 million from $41.7 million, reflecting the company's investments in commercial expansion and pipeline development. However, the 29% revenue growth outpaced the expense increases, leading to improved profitability margins.

  • Record HEPLISAV-B® quarterly net product revenue of $92 million, representing 31% year-over-year growth
  • Refines full year 2025 HEPLISAV-B net product revenue guidance range to $315 to $325 million, from $305 to $325 million
  • Top-line results in Part 1 of Phase 1/2 shingles vaccine trial expected in August 2025
  • Completed dosing in Part 1 of Phase 1/2 trial of pandemic influenza adjuvant program
  • Conference call today at 4:30 p.m. ET/1:30 p.m. PT

EMERYVILLE, Calif., Aug. 7, 2025 /PRNewswire/ -- Dynavax Technologies Corporation (Nasdaq: DVAX), a commercial-stage biopharmaceutical company developing and commercializing innovative vaccines, today reported financial results and provided a business update for the quarter ended June 30, 2025.

"In the second quarter of 2025, we continued our momentum by delivering robust Q2 results, achieving our highest net product revenue quarter ever for HEPLISAV-B, while further growing our market share leading position in the U.S. adult hepatitis B vaccine market," said Ryan Spencer, Chief Executive Officer of Dynavax. "Our vaccine pipeline remains on track, with key clinical milestones achieved or expected this year across multiple programs. We look forward to reporting our top-line Phase 1/2 trial results for our novel shingles program in the coming weeks, an opportunity to further demonstrate a potential best-in-class profile for this program with the potential to disrupt the multi-billion-dollar shingles vaccine market."

BUSINESS UPDATES
HEPLISAV-B® [Hepatitis B Vaccine (Recombinant), Adjuvanted]
HEPLISAV-B vaccine is the first and only adult hepatitis B vaccine approved in the U.S., the European Union and the United Kingdom that enables series completion with only two doses in one month. In the U.S., hepatitis B vaccination is recommended for adults aged 19 to 59, and for adults aged 60 and older with risk factors, while adults aged 60 and older without known risk factors may also be vaccinated.

  • HEPLISAV-B achieved record quarterly net product revenue of $91.9 million for the second quarter of 2025, an increase of 31% compared to $70.2 million for the second quarter of 2024.
  • HEPLISAV-B total estimated market share in the U.S. increased to approximately 45%, compared to approximately 42% for the second quarter 2024.
  • Dynavax continues to expect the hepatitis B adult vaccine market in the U.S. to expand to a peak of over $900 million in annual sales by 2030, with HEPLISAV-B expected to achieve at least 60% total market share. Additionally, Dynavax believes the HEPLISAV-B U.S. market opportunity will remain substantial beyond 2030 due to the ongoing penetration of the unvaccinated eligible adult population, observed revaccination practices by healthcare providers, and continued gains in market share.

Clinical and Preclinical Pipeline
Dynavax is advancing a pipeline of differentiated product candidates that leverage its CpG 1018® adjuvant, which has demonstrated its ability to enhance the immune response with a favorable tolerability profile in a wide range of clinical trials and real-world commercial use.

Shingles Vaccine Program:
Z-1018 is an investigational vaccine candidate being developed for the prevention of shingles in adults aged 50 years and older.

  • Dynavax has completed enrollment in Part 1 of a Phase 1/2 clinical trial comparing Z-1018 to Shingrix® in 441 healthy adults aged 50 to 69, and anticipates reporting top-line immunogenicity and safety data in August 2025.
  • Dynavax plans to advance the selected vaccine formulation and regimen from Part 1 into Part 2 of the Phase 1/2 study in adults over age 70 years to generate clinical proof-of-concept in this key population, with key endpoints including tolerability and immunogenicity comparisons to Shingrix, ahead of advancement into a pivotal trial.

Plague Vaccine Program:
Dynavax is developing a plague (rF1V) vaccine candidate adjuvanted with CpG 1018 in collaboration with, and fully funded by, the U.S. Department of Defense (DoD).

  • In the fourth quarter of 2024, Dynavax and the DoD executed a new agreement for approximately $30 million through the first half of 2027 to support additional clinical and manufacturing activities, including a Phase 2 clinical trial expected to initiate in the second half of 2025.

Pandemic Influenza Adjuvant Program:
Dynavax is evaluating CpG 1018 in an adjuvanted H5N1 influenza vaccine as a proof-of-concept for its potential use with pandemic influenza vaccines.

  • Dynavax recently completed enrollment and dosing in Part 1 of a randomized, active-controlled Phase 1/2 study to evaluate the safety and immunogenicity of an investigational H5N1 influenza vaccine adjuvanted with CpG 1018 in 101 participants aged 18 to 49.
  • Dynavax expects to use the Part 1 data to select the optimal formulations of CpG 1018 adjuvant to advance to Part 2 of the Phase 1/2 trial, with top-line immunogenicity and safety data expected in 2026.

Lyme Disease Vaccine Program:
Dynavax is developing an investigational multivalent protein subunit vaccine candidate adjuvanted with CpG 1018 for the prevention of Lyme disease, a bacterial infection that is the most common vector-borne illness in the Northern Hemisphere.

  • There are currently no approved human vaccines for Lyme disease, and current vaccine candidates in clinical development require three-dose primary series and annual boosters. Dynavax believes its investigational Lyme disease vaccine adjuvanted with CpG 1018, which has a demonstrated ability to amplify immune responses and improve durability of protection, has the potential for a differentiated and best-in-class vaccine profile.
  • Dynavax's Lyme disease vaccine candidate has progressed into Investigational New Drug (IND)-enabling studies, with plans to initiate clinical development in 2027.

HEPLISAV-B for Adults on Hemodialysis:

  • Dynavax plans to conduct an observational retrospective cohort study to support its sBLA filing for a HEPLISAV-B® vaccine regimen for adults on hemodialysis. In the first quarter of 2025, Dynavax received feedback from the U.S. Food and Drug Administration (FDA) that its proposed patient database may be acceptable for the observational retrospective cohort study, and Dynavax is engaging with the FDA to finalize the study protocol.

SECOND QUARTER 2025 FINANCIAL HIGHLIGHTS

  • Total revenues were $95.4 million for the second quarter of 2025, a 29% increase compared to $73.8 million for the second quarter of 2024.
  • HEPLISAV-B net product revenue was $91.9 million for the second quarter of 2025, a 31% increase compared to $70.2 million for the second quarter of 2024.
  • Cost of sales - product for HEPLISAV-B were $14.0 million for the second quarter of 2025, compared to $12.0 million for the second quarter of 2024.
  • Research and development expenses (R&D) were $16.6 million for the second quarter of 2025, compared to $15.0 million for the second quarter of 2024.
  • Selling, general, and administrative expenses (SG&A) were $50.4 million for the second quarter of 2025, compared to $41.7 million for the second quarter of 2024.
  • GAAP net income was $18.7 million, or $0.16 per share basic and $0.14 diluted in the second quarter of 2025, compared to GAAP net income of $11.4 million, or $0.09 per share basic and $0.08 diluted in the second quarter of 2024.
  • Adjusted EBITDA* was $37.3 million for the second quarter of 2025, compared to $20.5 million for the second quarter of 2024.
  • Cash, cash equivalents and marketable securities were $613.7 million as of June 30, 2025, compared to $713.8 million as of December 31, 2024.
  • Share repurchase program: As of June 30, 2025, Dynavax completed repurchases under its $200 million share repurchase program.

FULL YEAR 2025 FINANCIAL GUIDANCE
Dynavax is updating its full year 2025 financial guidance, based on its current operating plan: 

  • HEPLISAV-B net product revenue is expected in the range of $315 to $325 million, an increase compared to the prior range of $305 to $325 million.
  • Adjusted EBITDA* is expected to be at least $75 million.

* Non-GAAP financial measure. Please refer to the "Non-GAAP Financial Measures" section for details regarding this measure.

Conference Call and Webcast Information
Dynavax will host a conference call and live audio webcast on Thursday, August 7, 2025, at 4:30 p.m. ET/1:30 p.m. PT. The live audio webcast may be accessed through the "Events & Presentations" page on the "Investors" section of Dynavax's website at https://investors.dynavax.com/events-presentations. A replay of the webcast will be available for 30 days following the live event.

To dial into the call, participants will need to register for the call using the caller registration link. It is recommended that participants dial into the conference call or log into the webcast approximately 10 minutes prior to the call.

WHAT IS HEPLISAV-B?
HEPLISAV-B is a shot given to adults 18 years of age and older to help prevent infection caused by the hepatitis B virus. HEPLISAV-B is usually given in the arm muscle. HEPLISAV-B is given in 2 doses, 1 month apart, by a healthcare provider.

IMPORTANT SAFETY INFORMATION
Do not administer HEPLISAV-B to individuals with a history of severe allergic reaction (e.g., anaphylaxis) after a previous dose of any hepatitis B vaccine or to any component of HEPLISAV-B, including yeast.

Appropriate medical treatment and supervision must be available to manage possible anaphylactic reactions following administration of HEPLISAV-B.

Immunocompromised persons, including individuals receiving immunosuppressant therapy, may have a diminished immune response to HEPLISAV-B.

Hepatitis B has a long incubation period. HEPLISAV-B may not prevent hepatitis B infection in individuals who have an unrecognized hepatitis B infection at the time of vaccine administration.

The most common patient-reported adverse reactions reported within 7 days of vaccination were injection site pain (23%-39%), fatigue (11%-17%), and headache (8%-17%).

There are no adequate and well-controlled studies of HEPLISAV-B in pregnant individuals. Available data, primarily in individuals who received one dose of HEPLISAV-B in the 28 days prior to or during pregnancy, do not suggest an increased risk of major birth defects and miscarriage.

It is not known whether HEPLISAV-B is excreted in human milk.

Data are not available to assess the effects of HEPLISAV-B on the breastfed infant or on milk production/excretion.

Vaccination with HEPLISAV-B may not result in protection of all vaccine recipients.

Talk to your healthcare provider to determine if HEPLISAV-B is right for you.
Please see full Prescribing Information

About Dynavax
Dynavax is a commercial-stage biopharmaceutical company developing and commercializing innovative vaccines to help protect the world against infectious diseases. Dynavax has two commercial products, HEPLISAV-B® vaccine [Hepatitis B Vaccine (Recombinant), Adjuvanted], which is approved in the U.S., the European Union and the United Kingdom for the prevention of infection caused by all known subtypes of hepatitis B virus in adults 18 years of age and older, and CpG 1018® adjuvant, currently used in HEPLISAV-B and multiple adjuvanted COVID-19 vaccines. For more information about Dynavax's marketed products and development pipeline, visit www.dynavax.com.

Non-GAAP Financial Measures
To supplement financial results presented on a GAAP basis, Dynavax has included information about adjusted EBITDA, a non-GAAP financial measure. Dynavax believes the presentation of this non-GAAP financial measure, when viewed with its results under GAAP and the accompanying reconciliation, provide analysts, investors and other third parties with insights into how Dynavax evaluates normal operational activities, including its ability to generate cash from operations, on a comparable year-over-year basis, and manage its budgeting and forecasting.

In quarterly and annual reports, earnings press releases and conference calls, Dynavax may discuss Adjusted EBITDA to supplement its consolidated financial statements presented on a GAAP basis.

Adjusted EBITDA
Adjusted EBITDA is a non-GAAP financial measure that represents GAAP net income or loss adjusted to exclude interest expense, interest income, the benefit from or provision for income taxes, depreciation, amortization, stock-based compensation, and other adjustments to reflect changes that occur in Dynavax's business but do not represent ongoing operations, including loss on debt extinguishment and proxy contest costs. Adjusted EBITDA, as used by Dynavax, may be calculated differently from, and therefore may not be comparable to, similarly titled measures used by other companies.
There are several limitations related to the use of adjusted EBITDA rather than net income or loss, which is the nearest GAAP equivalent, such as:

  • adjusted EBITDA excludes depreciation and amortization, and, although these are non-cash expenses, the assets being depreciated or amortized may have to be replaced in the future, the cash requirements for which are not reflected in adjusted EBITDA;
  • adjusted EBITDA does not reflect changes in, or cash requirements for, working capital needs;
  • adjusted EBITDA does not reflect the benefit from or provision for income taxes or the cash requirements to pay taxes;
  • adjusted EBITDA does not reflect historical cash expenditures or future requirements for capital expenditures or contractual commitments;
  • Dynavax excludes stock-based compensation expense from adjusted EBITDA although: (i) it has been, and will continue to be for the foreseeable future, a significant recurring expense for its business and an important part of its compensation strategy; and (ii) if Dynavax did not pay out a portion of its compensation in the form of stock-based compensation, the cash salary expense included in operating expenses would be higher, which would affect its cash position;
  • From time to time, Dynavax may exclude other expenses that are episodic in nature and do not directly correlate to the cost of operating its business on an ongoing basis, such as loss on debt extinguishment and proxy contest costs.

Reconciliation of each historical non-GAAP financial measure to Adjusted EBITDA can be found in the table accompanying this press release. The Company has not provided a reconciliation of its full-year 2025 guidance for Adjusted EBITDA to the most directly comparable forward-looking GAAP measures because the Company is unable to predict, without unreasonable efforts, the timing and amount of items that would be included in such a reconciliation, including, but not limited to, stock-based compensation expense, income tax expense or provision for income taxes. These items are uncertain and depend on various factors that are outside of the Company's control or cannot be reasonably predicted. While the Company is unable to address the probable significance of these items, they could have a material impact on GAAP net income for the guidance period. A reconciliation of Adjusted EBITDA would imply a degree of precision and certainty as to these future items that does not exist and could be confusing to investors.

Forward-Looking Statements
This press release contains "forward-looking" statements within the meaning of Section 27A of the Securities Act of 1933, as amended, and Section 21E of the Securities Exchange Act of 1934, as amended, which are subject to a number of risks and uncertainties. All statements that are not historical facts are forward-looking statements. Forward-looking statements can generally be identified by the use of words such as "anticipate," "believe," "continue," "could," "estimate," "expect," "forecast," "will," "may," "plan," "potential,"  "would" and similar expressions, or the negatives thereof, or they may use future dates. Forward-looking statements made in this document include statements regarding Dynavax's expected financial results for the quarter ended June 30, 2025 and full year guidance, expectations regarding its future growth and long-term performance, extent and timing of market growth and market share beyond 2030, the timing of IND filings, initiation and completion of clinical studies, potential of its clinical and pre-clinical pipeline, expected timing for data readouts, and interaction with regulators. Actual results may differ materially from those set forth in this press release due to the risks and uncertainties inherent in Dynavax's business, including, the risk that market size or actual demand for its products may differ from its expectations, risks relating to its ability to commercialize and supply HEPLISAV-B, risks related to the timing of completion and results of current clinical studies, risks related to the development and pre-clinical and clinical testing of vaccines containing CpG 1018 adjuvant, as well as other risks detailed in the "Risk Factors" section of its Quarterly Report on Form 10-Q for the three months ended June 30, 2025 and periodic filings made thereafter, as well as discussions of potential risks, uncertainties and other important factors in its other filings with the U.S. Securities and Exchange Commission. These forward-looking statements are made as of the date hereof, are qualified in their entirety by this cautionary statement and Dynavax undertakes no obligation to revise or update information herein to reflect events or circumstances in the future, even if new information becomes available. Information on Dynavax's website at www.dynavax.com is not incorporated by reference in its current periodic reports with the SEC.

Reference herein to any specific commercial products, process, or service by trade name, trademark, manufacturer, or otherwise, does not constitute or imply its endorsement, recommendation, or favoring by the U.S. Government and shall not be used for advertising or product endorsement purposes.

For Investors/Media:
Paul Cox
pcox@dynavax.com
510-665-0499

Nicole Arndt
narndt@dynavax.com
510-665-7264

 

DYNAVAX TECHNOLOGIES CORPORATION

CONSOLIDATED STATEMENTS OF OPERATIONS

(In thousands, except per share amounts)

(Unaudited) 



Three Months Ended June 30,


Six Months Ended June 30,


2025


2024


2025


2024

Revenues:








Product revenue, net

$            91,872


$            70,188


$          156,831


$          118,032

Other revenue

3,570


3,607


6,775


6,552

Total revenues

95,442


73,795


163,606


124,584

Operating expenses:








Cost of sales - product

14,035


11,985


27,804


22,952

Research and development

16,619


14,950


35,996


28,478

Selling, general and administrative

50,359


41,662


98,037


85,727

Bad debt expense



10,970


Total operating expenses

81,013


68,597


172,807


137,157

Income (loss) from operations

14,429


5,198


(9,201)


(12,573)

Other income (expense):








Interest income

6,798


9,201


14,537


18,668

Interest expense

(1,641)


(1,698)


(3,333)


(3,393)

Sublease income

2,226


2,205


4,452


603

Loss on debt extinguishment



(82,095)


Other (loss) income

(596)



(1,019)


103

Net income (loss) before income taxes

21,216


14,906


(76,659)


3,408

Provision for income taxes

(2,495)


(3,520)


(719)


(743)

Net income (loss)

$            18,721


$            11,386


$          (77,378)


$              2,665

Net income (loss) per share attributable to common     
stockholders








Basic

$                0.16


$                0.09


$              (0.63)


$                0.02

Diluted

$                0.14


$                0.08


$              (0.63)


$                0.02

Weighted-average shares used in computing net
income (loss) per share attributable to common
stockholders:








Basic

119,317


130,916


122,079


130,551

Diluted

138,356


154,468


122,079


133,582

 

DYNAVAX TECHNOLOGIES CORPORATION

SELECTED BALANCE SHEET DATA

(In thousands)

(Unaudited)



June 30,
2025


December 31,
2024

Assets




Cash, cash equivalents and marketable securities     

$                613,729


$                713,834

Inventories

$                  75,687


$                  70,054

Other current assets

$                  96,296


$                  65,053

Total current assets

$                785,712


$                848,941

Total non-current assets

$                132,737


$                137,315

Total assets

$                918,449


$                986,256





Liabilities and stockholders' equity




Total current liabilities

$                118,230


$                  78,634

Total long-term liabilities

$                306,057


$                310,823

Stockholders' equity

$                494,162


$                596,799

Total liabilities and stockholders' equity

$                918,449


$                986,256

 

DYNAVAX TECHNOLOGIES CORPORATION

RECONCILIATION OF GAAP NET LOSS TO ADJUSTED EBITDA

(In thousands)

(Unaudited)



Three Months Ended


Six Months Ended


June 30,


June 30,


2025


2024


2025


2024

GAAP net income (loss)

$           18,721


$           11,386


$          (77,378)


$              2,665

Adjustments:








Depreciation & amortization

374


376


748


751

Interest income

(6,798)


(9,201)


(14,537)


(18,668)

Interest expense

1,641


1,698


3,333


3,393

Benefit from income taxes

2,495


3,520


719


743

Total adjustments

(2,288)


(3,607)


(9,737)


(13,781)

EBITDA

16,433


7,779


(87,115)


(11,116)

Stock-based compensation

12,087


12,685


25,536


24,829

Loss on debt extinguishment     



82,095


Proxy contest costs

8,827



12,520


Adjusted EBITDA

$           37,347


$           20,464


$           33,036


$           13,713

Cision View original content to download multimedia:https://www.prnewswire.com/news-releases/dynavax-reports-second-quarter-2025-financial-results-302524697.html

SOURCE Dynavax Technologies

FAQ

What were Dynavax (DVAX) Q2 2025 earnings results?

Dynavax reported Q2 2025 total revenues of $95.4M, with HEPLISAV-B net product revenue of $91.9M. GAAP net income was $18.7M or $0.16 per share.

What is DVAX's market share for HEPLISAV-B in 2025?

HEPLISAV-B's total estimated market share in the U.S. reached 45% in Q2 2025, up from approximately 42% in Q2 2024.

What is Dynavax's revenue guidance for HEPLISAV-B in 2025?

Dynavax refined its HEPLISAV-B net product revenue guidance to $315-325 million for full year 2025, raised from the previous range of $305-325 million.

When will Dynavax report Phase 1/2 shingles vaccine trial results?

Dynavax expects to report top-line results from Part 1 of the Phase 1/2 shingles vaccine trial in August 2025.

What is Dynavax's cash position as of Q2 2025?

Dynavax reported cash, cash equivalents and marketable securities of $613.7 million as of June 30, 2025.
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