Daxor Announces Duke University Study on Blood Volume Analysis in Heart Failure Published in American Heart Journal

Rhea-AI Summary

Daxor Corporation (DXR) announced significant findings from a Duke University Medical Center study published in the American Heart Journal regarding Blood Volume Analysis (BVA) in heart failure patients. The research demonstrates BVA's effectiveness in differentiating between true and dilutional anemia in heart failure patients.

Key findings revealed that among heart failure patients diagnosed with anemia, 60% had true anemia while 40% had dilutional pseudo-anemia. Patients with dilutional pseudo-anemia showed higher tendencies toward heart failure hospitalization. The study also found that heart failure patients with red blood cell mass deficit or true anemia demonstrated poorer exercise capacity.

The research validates BVA's importance in heart failure management, as standard blood panels are not sufficiently sensitive or specific for this purpose.

Positive

• Study validates BVA technology's effectiveness in differentiating anemia types in heart failure patients
• Research published in prestigious American Heart Journal adds credibility to Daxor's technology
• BVA addresses a key requirement in Heart Failure Guidelines by major cardiovascular societies

Negative

• None.

Published Research Demonstrates the Value of BVA in Meeting Key Goal of Identifying Anemia in Heart Failure Patients

Oak Ridge, TN, May 14, 2025 (GLOBE NEWSWIRE) -- Daxor Corporation (Nasdaq: DXR), Daxor Corporation, the global leader in blood volume measurement technology, today announces significant new findings from Duke University Medical Center published in the prestigious American Heart Journal. The research demonstrates how Blood Volume Analysis (BVA) enables precise measurement of red blood cell mass (RBCM) and effectively differentiates between true and dilutional anemia in heart failure (HF) patients.

The detection of true anemia and its management is a key part of Heart Failure Guidelines published by cardiovascular societies, including the American College of Cardiology and the Heart Failure Society of America, but standard blood panels of hematocrit and hemoglobin levels are not sensitive or specific to enable care for this key objective.

The study, titled, "Relationship of Red Blood Cell Mass Profiles and Anemia Type to Outcomes and Cardiopulmonary Exercise Performance in Chronic Heart Failure," highlights the connections between RBCM profiles using BVA, different anemia types, heart failure outcomes, and cardiopulmonary exercise test (CPET) parameters.

Dr. Veraprapas Kittipibul, the study's lead investigator, outlined key findings:

• Anemia is prevalent in heart failure patients and can be categorized by type using BVA.
• Among heart failure patients diagnosed with anemia by WHO hemoglobin criteria, 60% had true anemia while 40% had dilutional pseudo-anemia. (Only truly anemic patients need red cell therapy while pseudo-anemic patients do not, yet WHO criteria does not differentiate this need.)
• Patients with dilutional pseudo-anemia.showed a tendency toward higher heart failure hospitalization compared to those with no anemia or true anemia.
• No significant difference in heart failure hospitalization rates was observed across different RBCM profiles.
• Heart failure patients with RBCM deficit or true anemia demonstrated poorer exercise capacity.

“This research from Duke University provides additional compelling evidence for the value of BVA in heart failure management,” said John L. Jefferies, MD, MPH, MBA, Daxor's Chief Medical Officer. “The ability to differentiate between true and dilutional pseudo-anemia fundamentally changes a patient’s treatment approach. Accurate volume status directly impacts therapeutic decisions, patient outcomes and quality of life, and reinforces why blood volume measurement should be standard in comprehensive heart failure care."

About Daxor Corporation

Daxor Corporation (Nasdaq: DXR), is the global leader in blood volume measurement technology focused on blood volume testing innovation. We developed and market the BVA-100^® (Blood Volume Analyzer), the only diagnostic blood test cleared by the FDA to provide safe, accurate, objective quantification of blood volume status and composition compared to patient-specific norms. Over 70,000+ tests have been performed at leading hospital centers across the U.S., enhancing hospital performance metrics in a broad range of surgical and medical conditions, including significantly reducing mortality and readmissions in heart failure and critical care. Daxor has several ongoing trials in the areas of heart failure treatment with support from the NIH and is under contract developing analyzers to improve combat casualty care with the U.S. Department of Defense. Daxor's mission is to advance healthcare by enabling optimal fluid management with blood volume analysis. Daxor’s vision is optimal blood volume for all. For more information, please visit our website at Daxor.com. Sign up to receive news on Daxor’s innovative technology HERE.

Forward-Looking Statements

Certain statements in this release may include forward-looking statements within the meaning of the Private Securities Litigation Reform Act of 1995, including without limitation, statements regarding the impact of hiring sales staff and expansion of our distribution channels. Forward-looking statements are predictions, projections and other statements about future events that are based on current expectations and assumptions and, as a result, are subject to risks and uncertainties. Many factors could cause actual future events to differ materially from the forward-looking statements in this release, including, without limitation, those risk associated with our post-market clinical data collection activities, benefits of our products to patients, our expectations with respect to product development and commercialization efforts, our ability to increase market and physician acceptance of our products, potentially competitive product offerings, intellectual property protection, FDA regulatory actions, our ability to integrate acquired businesses, our expectations regarding anticipated synergies with and benefits from acquired businesses, and additional other risks and uncertainties described in our filings with the SEC. Forward-looking statements speak only as of the date when made. Daxor does not assume any obligation to publicly update or revise any forward-looking statements, whether as a result of new information, future events or otherwise.

Investor Relations Contact:
Bret Shapiro
Sr. Managing Partner, CORE IR
1-516-222-2560
brets@coreir.com

FAQ

What did the Duke University study reveal about Daxor's (DXR) Blood Volume Analysis technology?

The study showed BVA can effectively differentiate between true anemia (60%) and dilutional pseudo-anemia (40%) in heart failure patients, with true anemia patients requiring red cell therapy while pseudo-anemic patients do not.

How does Daxor's (DXR) Blood Volume Analysis impact heart failure patient outcomes?

BVA helps identify accurate volume status and anemia type, which directly impacts therapeutic decisions and patient outcomes. The study found patients with RBCM deficit or true anemia showed poorer exercise capacity.

What percentage of heart failure patients have true vs. pseudo-anemia according to Daxor's (DXR) study?

According to the Duke University study, 60% of heart failure patients diagnosed with anemia had true anemia, while 40% had dilutional pseudo-anemia.

Why is Daxor's (DXR) Blood Volume Analysis important for heart failure treatment?

BVA is important because standard blood panels aren't sensitive or specific enough to meet Heart Failure Guidelines requirements. BVA enables precise measurement of red blood cell mass and helps determine appropriate treatment approaches.