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EyePoint Pharmaceuticals reported financial results for the first quarter of 2024 and highlighted recent corporate developments. The company has $299 million in cash and investments as of March 31, 2024, ensuring cash runway through Phase 3 trials for DURAVYU for wet AMD in 2026. Despite the Phase 2 PAVIA trial not meeting the primary endpoint, DURAVYU showed a biologic effect in patients with NPDR. EyePoint plans to initiate the Phase 3 LUGANO trial for DURAVYU in wet AMD and present Phase 2 VERONA trial data in 2025.
EyePoint Pharmaceuticals announced topline results of the Phase 2 PAVIA trial evaluating DURAVYU in patients with non-proliferative diabetic retinopathy (NPDR). Although the trial did not meet the primary endpoint, DURAVYU demonstrated a favorable safety profile and potential in reducing NPDR progression at nine months. The Company plans to review full 12-month data to determine the future path for DURAVYU. Dr. Duker expressed optimism for DURAVYU's potential as a maintenance therapy for wet AMD patients based on positive data from DAVIO 2.
