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AI Has Left the Lab: F5 Report Reveals 78% of Enterprises Now Run AI Inference as a Core Operation

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Key Terms

ai inference technical
AI inference is the step where a trained artificial intelligence model uses its learned patterns to analyze new data and produce an output — for example, predicting a stock trend, flagging a medical image, or generating text, much like using a recipe to cook a meal. It matters to investors because inference determines real-world performance, speed, and cost of AI features, affects user experience and scalability, and influences operating expenses, regulatory compliance, and competitive advantage.
hybrid multicloud technical
A hybrid multicloud is an IT approach that combines an organization’s private on‑site computing resources with services from two or more public cloud providers, letting data and applications move between them as needed. For investors, it matters because this setup can improve flexibility, resilience and cost control—like storing goods in a mix of your own warehouse and several rented facilities—while also creating vendor, security and execution risks that can affect a company’s profitability and growth prospects.
agentic ai technical
Agentic AI refers to computer systems that can make their own decisions and take actions without needing someone to tell them what to do each time. It's like giving a robot a degree of independence to solve problems or achieve goals on its own, which matters because it could change how we work and interact with technology in everyday life.
ai-as-a-service financial
A subscription-style offering that lets businesses access ready-made artificial intelligence tools and services over the internet instead of building them from scratch. Think of it as renting a powerful, constantly updated toolbox of smart features — like language understanding or image recognition — that a company plugs into its products or operations. Investors care because it usually creates recurring revenue, fast customer scaling, and predictable costs, but also ties value to usage, data quality, and ongoing platform trust.
multicloud technical
Multicloud is the practice of a company using cloud computing services from two or more different providers instead of relying on just one, like keeping money in several banks so you can use each bank’s strengths. For investors, it matters because it can lower operational risk, improve reliability and flexibility, and affect costs and growth prospects — all of which influence a company’s profitability and competitive position.
prompt layers technical
Prompt layers are a way of organizing the set of instructions and context given to an artificial-intelligence model by stacking or separating them into distinct levels—for example, general goals, specific steps, and real-time data—so the model processes each layer in order. Like a multi-step recipe that guides a cook through planning, prep and final plating, prompt layers help produce more reliable, reproducible outputs, which matters to investors because they affect product quality, operational risk, regulatory compliance, and the credibility of AI-driven claims.
application programming interfaces technical
Application programming interfaces (APIs) are sets of rules and tools that let different software programs talk to each other, like a waiter taking and delivering orders between a diner and the kitchen. For investors, APIs matter because they let companies add features, connect with partners, scale services and create new revenue streams quickly; they also introduce risks around reliance on third parties, security and ongoing maintenance costs.
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2026 F5 State of Application Strategy Report shows production AI model and agentic AI trends fundamentally shifting how enterprises deliver and secure apps in hybrid multicloud environments

SEATTLE--(BUSINESS WIRE)-- F5 (NASDAQ: FFIV), the global leader in delivering and securing every app and API, today released its annual State of Application Strategy (SOAS) Report, revealing that artificial intelligence has crossed a critical threshold: it is no longer an experimental initiative but a production workload demanding the same operational rigor as any mission-critical system. The research, based on responses from hundreds of enterprise IT and security leaders worldwide, shows that 78% of organizations are now running AI inference themselves—a clear signal that enterprises are choosing control over convenience as AI becomes central to business operations.

The findings arrive at a pivotal moment. With 93% of organizations operating across multiple clouds and 86% distributing applications across hybrid multicloud environments, the complexity of delivering and securing AI workloads has reached a new inflection point.

“AI has moved from experimentation to operations. The question now is not whether companies will use AI, but whether they can run it reliably, securely, and at scale,” said Kunal Anand, Chief Product Officer at F5. “This year’s data shows a clear shift: AI inference is becoming core to the business, which means AI delivery is now a traffic management challenge, and AI security is now a governance and control challenge. The companies that understand this shift early will be the ones that move faster and more safely.”

Key findings from the 2026 report

AI is an operational reality, not an experiment

AI is no longer a flashy experiment or future concern; it has become an operational reality deeply embedded in daily business outcomes. Organizations now coordinate an average of seven AI models in production, with 77% reporting that inference—running trained models to generate outputs—has become their dominant AI activity, surpassing model building and training. This shift emphasizes the operational governance of AI systems, treating inference as a managed, policy-driven workload integrated into the application stack and subject to the same architectural, security, and scalability demands as other production systems.

AI-as-a-Service strategies are already considered risky

AI-as-a-Service strategies are widely acknowledged as risky and misaligned with modern enterprise realities. Only 8% of organizations rely exclusively on public AI services. The overwhelming majority are building diversified model portfolios, requiring sophisticated routing, fallback, and policy controls to manage cost, accuracy, and availability.

Hybrid multicloud is the new delivery standard

This reflects the broader trend of multicloud, multi-environment operations, with 93% of enterprises leveraging multicloud setups and 86% running apps across on-prem, public cloud, and colocation environments. Similarly, AI workloads require advanced routing, fallback, and policy controls to optimize cost, accuracy, and availability. A unified delivery, security, and governance strategy across environments is now essential to manage the complexities of modern AI and application deployments.

While managing the complexities of such diverse infrastructures is essential, it must be paired with precise control across environment boundaries to ensure seamless integration, consistent policy enforcement, and unified security strategies. This balance reduces silos, minimizes operational disruptions, and maintains governance at scale, enabling enterprises to optimize cost, accuracy, and availability while unlocking the full potential of hybrid multicloud systems for AI and application deployments.

AI security and governance are now systemic requirements

As AI systems enter full-scale production, security has become an enterprise-wide priority. The report shows 88% of organizations have faced AI-related security challenges, while 98% are preparing for agentic AI—autonomous systems needing identities, permissions, and guardrails like human users. This shifts the security perimeter to prompt, token, and identity layers, rendering traditional models insufficient and making governance across every layer essential.

Prompt and token layers: The control points driving AI delivery

The report reveals a significant shift in AI workload management, with control moving to prompts, tokens, and APIs. Nearly 29% of organizations identify prompt layers as the top delivery mechanism, while 23% prioritize token layers for delivery and security. Governing these layers is key to optimizing cost, performance, and safety, giving enterprises a competitive edge over those focused solely on infrastructure.

Why it matters

The 2026 State of Application Strategy Report offers a data-driven view of the forces reshaping enterprise technology: the rapid operationalization of AI, the permanence of hybrid multicloud, and an evolving threat landscape that demands new thinking about security and control.

AI maturity is quickly becoming a measurable indicator of operational resilience and competitive positioning. Organizations that invest in observability, authentication, and unified control across every environment where AI runs will be the ones that turn AI’s promise into lasting business value.

Download the full 2026 State of Application Strategy Report to access complete findings, industry benchmarks, and strategic recommendations.

Additional resources

About F5

F5, Inc. (NASDAQ: FFIV) is the global leader that delivers and secures every app. Backed by three decades of expertise, F5 has built the industry’s premier platform—F5 Application Delivery and Security Platform (ADSP)—to deliver and secure every app, every API, anywhere: on-premises, in the cloud, at the edge, and across hybrid, multicloud environments. F5 is committed to innovating and partnering with the world’s largest and most advanced organizations to deliver fast, available, and secure digital experiences. Together, we help each other thrive and bring a better digital world to life.

For more information visit f5.com
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F5 is a trademark, service mark, or tradename of F5, Inc., in the U.S. and other countries. All other product and company names herein may be trademarks of their respective owners.

Source: F5, Inc.

Dan Sorensen
F5
(650) 228-4842
d.sorensen@f5.com

Holly Lancaster
We. Communications
(415) 547-7054
hlancaster@wecommunications.com

Source: F5, Inc.