Foghorn Therapeutics Inc. Stock Price, News & Analysis

Foghorn Therapeutics (Nasdaq: FHTX) released its Q2 2024 financial and corporate update, highlighting key advancements and financial status. The company reported a successful $110 million financing, boosting cash reserves to $285.2 million, extending expected cash runway into 2027.

Clinical milestones include anticipated topline Phase 1 data for FHD-286 in AML patients in Q4 2024, and the dosing of the first patient in the Phase 1 trial for SMARCA2 selective inhibitor FHD-909 in H2 2024. IND-enabling studies for the Selective CBP degrader program are also on track for year-end 2024.

Financial highlights show collaboration revenue of $6.9 million, up from $5.6 million YoY. R&D expenses decreased to $23.8 million from $29.2 million, and G&A expenses dropped to $7.3 million from $8.4 million. The net loss narrowed to $23.0 million from $29.5 million YoY.

Foghorn continues to leverage its Gene Traffic Control platform to develop innovative oncology treatments.

Flagship Pioneering has unveiled Abiologics, a company developing a new class of supranatural and programmable medicines called Synteins™. These are computationally-generated and synthesized with novel building blocks, aiming to overcome limitations of traditional biologics. The Abiologics platform uses generative AI and high-throughput chemical protein synthesis to create Synteins with extraordinary properties.

Flagship has initially committed $50 million to advance the platform and develop a pipeline of medicines, focusing on oncology and immunology. Synteins can be programmed to interact with virtually any therapeutic target while evading the body's natural defenses, offering advantages such as less frequent dosing, oral delivery, and access to previously unreachable parts of the body.

Flagship Pioneering, a bioplatform innovation company, announced it has raised $3.6 billion to foster the growth of 25 groundbreaking companies in human health, sustainability, and AI. This includes $2.6 billion into Fund VIII and $1 billion from sector-specific partnerships, bringing the total capital raised since 2021 to $6.4 billion. The company now operates with an aggregate capital pool of $10.9 billion and manages $14 billion in assets.

Flagship's recent partnerships include collaborations with Pfizer, Samsung, Thermo Fisher Scientific, and Novo Nordisk. These alliances are part of Flagship's Innovation Supply Chain Partnership (ISC) model, which maximizes innovation across various stages of product development.

The company has expanded globally, establishing hubs in London and Singapore to enhance its R&D collaborations and access international talent. Flagship has also bolstered its leadership team with several key hires and promotions to drive its growth and innovation strategy.

Flagship Pioneering, a bioplatform innovation company, has expanded its leadership team with new appointments and promotions. These changes accompany an expanded capital base of $3.6 billion for the development of 25 breakthrough platform companies in human health, sustainability, and AI.

Key promotions include Lovisa Afzelius to General Partner, Paul Biondi to General Partner, Dina Ciarimboli as General Counsel, Marcello Damiani as Senior Partner, Gary Pisano as Chief Strategist, and other critical roles filled by experienced professionals. These leaders bring significant expertise from major firms like Pfizer, Bristol-Myers Squibb, Moderna, and Harvard Business School.

Flagship aims to leverage these appointments to drive innovation, enhance strategic partnerships, and improve operational efficiency across its ecosystem of companies, furthering its mission to pioneer transformative technologies.

Foghorn Therapeutics (Nasdaq: FHTX), a clinical-stage biotech company focused on treating serious diseases by correcting abnormal gene expression, announced its participation in two major investor conferences in June 2024. The Jefferies Global Healthcare Conference will feature Adrian Gottschalk, CEO, presenting on June 5, 2024, at 3:30 p.m. ET in New York. The Goldman Sachs 45th Annual Global Healthcare Conference will also include a presentation by Gottschalk on June 10, 2024, at 3:20 p.m. ET in Miami Beach. Both presentations will be accessible via webcast for 30 days on the company's website.

Foghorn Therapeutics has successfully closed a registered direct offering, raising approximately $110 million. This funding will bolster the company’s platform and advance its diverse pipeline of treatments for diseases, especially in oncology. The offering, which includes new and existing investors like BVF Partners and Flagship Pioneering, strengthens Foghorn's balance sheet, extending its cash runway into 2027. With $310 million in cash, cash equivalents, and short-term investments, the company is well-positioned for upcoming data readouts and clinical milestones. The offering priced 12,743,039 common shares at $5.51 each, and pre-funded warrants to buy 7,220,794 shares at $5.5099 each.

Foghorn Therapeutics (FHTX) has announced a registered direct offering of 12,743,039 shares of its common stock at $5.51 per share and pre-funded warrants for 7,220,794 shares at $5.5099 per warrant. This offering aims to raise approximately $110 million in gross proceeds. The closing is expected around May 22, 2024, pending customary conditions. Proceeds will be used for advancing preclinical and clinical programs and general corporate purposes. Jefferies, TD Cowen, and Evercore ISI are managing the offering. The securities are offered pursuant to an effective shelf registration statement filed with the SEC.

Foghorn Therapeutics Inc. provided a financial and corporate update for Q1 2024. The company showcased strong preclinical anti-tumor activity in multiple pipeline programs and progress in AML and NSCLC studies, with data expected in the second half of 2024. IND filing for a first-in-class oral BRM inhibitor was submitted, along with updates on selective CBP and EP300 degrader programs. The company presented promising data at AACR, appointed a new CFO, and reported cash reserves of $206.7 million.