STOCK TITAN

Gain Therapeutics to Present at the 38th Annual ROTH Conference

Rhea-AI Impact
(Neutral)
Rhea-AI Sentiment
(Positive)
Tags

Gain Therapeutics (NASDAQ: GANX) announced that Gene Mack, President and CEO, will participate in a fireside chat and one-on-one meetings at the 38th Annual ROTH Conference in Dana Point, CA, March 22-24, 2026. The fireside chat is scheduled for March 23, 2026 at 11:30 a.m. PT.

Investors can access a live webcast or replay via the company website or contact ir@gaintherapeutics.com to arrange meetings through ROTH representatives.

Loading...
Loading translation...

Positive

  • None.

Negative

  • None.

Key Figures

Net loss: $5.28M EPS: $(0.15) Net loss (9M): $15.62M +5 more
8 metrics
Net loss $5.28M Q3 2025 net loss vs. $4.49M prior year
EPS $(0.15) Q3 2025 loss per share
Net loss (9M) $15.62M First nine months of 2025
Cash & equivalents $8.81M Balance at Sept 30, 2025; less than 12-month runway
Shelf capacity $100,000,000 Maximum mixed shelf registration on Form S-3/A
Shares outstanding 36,241,000 Common shares outstanding as of Nov 3, 2025
Net loss (6M) $10.34M Six months ended June 30, 2025
Cash & equivalents $6.69M Balance at June 30, 2025, per 10-Q

Market Reality Check

Price: $1.90 Vol: Volume 692,375 is below t...
normal vol
$1.90 Last Close
Volume Volume 692,375 is below the 20-day average of 951,783, suggesting no unusual trading ahead of this conference update. normal
Technical Shares at $1.90 are trading below the 200-day MA of $2.16 and well under the $4.34 52-week high.

Peers on Argus

Two biotech peers, CUE and INKT, appeared on the momentum scanner, both moving d...
2 Down

Two biotech peers, CUE and INKT, appeared on the momentum scanner, both moving down about 5–6%. This aligns with broader weakness in the biotechnology group around this time.

Historical Context

5 past events · Latest: Mar 18 (Positive)
Pattern 5 events
Date Event Sentiment Move Catalyst
Mar 18 Clinical data update Positive -25.6% Phase 1b GT-02287 and new chemical series data presented at AD/PD 2026.
Mar 12 Conference & FDA update Positive -3.2% AD/PD 2026 presentation plans and U.S. FDA IND response timeline for Phase 2.
Feb 19 Conference participation Neutral +3.3% Oppenheimer conference fireside chat and one-on-one investor meetings.
Jan 07 Conference participation Neutral -5.5% Participation in multiple JPM Healthcare Conference–week investor events.
Jan 06 Biomarker data update Positive -14.1% Phase 1b GT-02287 biomarker and clinical results showing large GluSph reductions.
Pattern Detected

Recent positive clinical and biomarker updates have often been followed by negative price reactions, indicating a pattern of selling into good news.

Recent Company History

Over the past six months, GANX has focused on advancing GT-02287 and increasing visibility through conferences. Biomarker and clinical data releases on Jan 6, 2026 and Dec 18, 2025 highlighted substantial GluSph reductions and supportive safety data, yet shares fell 14.14% and showed pressure after these updates. The Mar 18, 2026 AD/PD Phase 1b data coincided with a 25.57% drop. Multiple conference participation announcements (January, February) produced mixed but generally modest moves. Today’s ROTH conference news fits the pattern of ongoing outreach rather than a new clinical or financial catalyst.

Regulatory & Risk Context

Active S-3 Shelf · $100,000,000
Shelf Active
Active S-3 Shelf Registration 2025-11-07
$100,000,000 registered capacity

An amended mixed shelf registration on Nov 7, 2025 registered up to $100,000,000 of various securities for potential future offerings. The filing is noted as not yet effective and has not been used to date, but it provides flexibility to raise capital for working capital and general corporate purposes if activated.

Market Pulse Summary

This announcement highlights GANX’s participation in the 38th Annual ROTH Conference, continuing a s...
Analysis

This announcement highlights GANX’s participation in the 38th Annual ROTH Conference, continuing a strategy of active investor outreach via events and fireside chats. It follows recent Phase 1b data for GT-02287 and ongoing regulatory updates. From a fundamental standpoint, investors may focus on liquidity metrics such as cash of $8.81M at Sept 30, 2025, prior net losses of $5.28M in Q3 2025, and the existing $100,000,000 mixed shelf that could support future capital raising.

Key Terms

allosteric, small molecule
2 terms
allosteric medical
"leading the discovery and development of the next generation of allosteric small molecule therapies"
Allosteric describes a way drugs or molecules change a biological target’s behavior by attaching at a spot separate from the main active site, causing the target to shift shape and work differently. For investors, allosteric mechanisms can mean more precise drugs with fewer side effects, fresh patent pathways and differentiated market potential, because they can fine-tune a target rather than simply switching it fully on or off—like using a dimmer knob instead of a basic light switch.
small molecule medical
"leading the discovery and development of the next generation of allosteric small molecule therapies"
A small molecule is a low-weight chemical compound that can enter cells easily and interact with specific proteins or biological pathways to change how they work, much like a small key fitting into a lock. Investors care because small molecules are a common and often faster route to develop medicines, can be manufactured at scale, and may offer clearer regulatory and commercial paths compared with larger biologic therapies, affecting potential costs, timelines and returns.

AI-generated analysis. Not financial advice.

BETHESDA, Md., March 19, 2026 (GLOBE NEWSWIRE) -- Gain Therapeutics, Inc. (Nasdaq: GANX) (“Gain”, or the “Company”), a clinical-stage biotechnology company leading the discovery and development of the next generation of allosteric small molecule therapies, today announced that Gene Mack, President and CEO, will participate in a fireside chat and one-on-one meetings at the 38th Annual ROTH Conference, being held March 22-24, 2026, in Dana Point, CA.

Fireside Chat Details

Date: Monday, March 23, 2026

Time: 11:30 a.m. PT

Access a live webcast or a replay of the fireside chat here or visit the “Investors & Media/News & Events” section of the Company’s website at https://gaintherapeutics.com.

If you are unable to attend the conference and would like to schedule a meeting with Gain management, please contact either your ROTH representative or ir@gaintherapeutics.com.

About Gain Therapeutics, Inc.
Gain Therapeutics, Inc. is a clinical-stage biotechnology company leading the discovery and development of next generation allosteric therapies. Gain’s lead drug candidate, GT-02287 is currently being evaluated for the treatment of Parkinson’s disease with or without a GBA1 mutation in a Phase 1b clinical trial. GT-02287 has further potential in Gaucher’s disease, dementia with Lewy bodies, and Alzheimer’s disease. Gain has multiple undisclosed preclinical assets targeting lysosomal storage disorders, metabolic diseases, and solid tumors.

Gain’s unique approach enables the discovery of novel, allosteric small molecule modulators that can restore or disrupt protein function. Deploying its highly advanced Magellan™ platform, Gain is accelerating drug discovery and unlocking novel disease-modifying treatments for untreatable or difficult-to-treat disorders including neurodegenerative diseases, rare genetic disorders and oncology.

Forward-Looking Statements
This release contains “forward-looking statements” made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. These statements are typically preceded by words such as “believes,” “expects,” “anticipates,” “intends,” “will,” “may,” “should,” or similar expressions. These forward-looking statements reflect management’s current knowledge, assumptions, judgment and expectations regarding future performance or events. Although management believes that the expectations reflected in such statements are reasonable, they give no assurance that such expectations will prove to be correct or that those goals will be achieved, and you should be aware that actual results could differ materially from those contained in the forward-looking statements. Such forward-looking statements include, but are not limited to, statements regarding: the development of the Company’s current or future product candidates including GT-02287 and GT-04686; expectations regarding the completion and timing of results from a Phase 1b clinical study for GT-02287, including any extension studies; expectations regarding the timing of patient enrollment for a Phase 1b clinical study for GT-02287, including any extension studies; the timing of any submissions to the FDA or other regulatory bodies and agencies and the timing of any responses from the FDA or other regulatory bodies and agencies; the timing of the commencement of any Phase 2 clinical studies for GT-02287; and the potential therapeutic and clinical benefits of the Company’s product candidates, including GT-02287 and GT-04686. For a further description of the risks and uncertainties that could cause actual results to differ from those expressed in these forward-looking statements, as well as risks relating to the Company’s business in general, please refer to the Company’s Form 10-K for the year ended December 31, 2024, and other filings made with the SEC. All forward-looking statements are expressly qualified in their entirety by this cautionary notice. You are cautioned not to place undue reliance on any forward-looking statements, which speak only as of the date of this release. We have no obligation, and expressly disclaim any obligation, to update, revise or correct any of the forward-looking statements, whether because of new information, future events or otherwise.

Investors:
Gain Therapeutics, Inc. 
Apaar Jammu 
Director, Investor Relations and Public Relations
ajammu@gaintherapeutics.com

LifeSci Advisors LLC
Chuck Padala
Managing Director
chuck@lifesciadvisors.com

Media:
Russo Partners LLC
Nic Johnson and Elio Ambrosio
nic.johnson@russopartnersllc.com
elio.ambrosio@russopartnersllc.com
(760) 846-9256


FAQ

When will Gain Therapeutics (GANX) present at the 38th Annual ROTH Conference?

The fireside chat is on March 23, 2026 at 11:30 a.m. PT. According to the company, Gene Mack will speak in a fireside chat and hold one-on-one meetings during the March 22-24, 2026 conference in Dana Point, California.

How can investors watch Gain Therapeutics (GANX) at the ROTH Conference if they cannot attend?

Investors can watch a live webcast or replay via the company website. According to the company, the fireside chat will be accessible through the Investors & Media/News & Events section at gaintherapeutics.com.

Who from Gain Therapeutics (GANX) will participate at the ROTH Conference?

Gene Mack, President and CEO, will participate in a fireside chat and one-on-one meetings. According to the company, he will represent Gain during the March 22-24, 2026 conference in Dana Point, CA.

How can I schedule a meeting with Gain Therapeutics (GANX) management at ROTH Conference?

To schedule a meeting, contact your ROTH representative or email ir@gaintherapeutics.com. According to the company, meetings can be arranged through ROTH or directly via the investor relations email provided.

Where is the 38th Annual ROTH Conference held for Gain Therapeutics (GANX)?

The conference is being held in Dana Point, California from March 22-24, 2026. According to the company, Gain Therapeutics will host the fireside chat on March 23, 2026 at 11:30 a.m. PT.

Will Gain Therapeutics (GANX) provide a replay of the ROTH Conference fireside chat?

Yes, a replay will be available on the company website. According to the company, both a live webcast and a replay of the March 23 fireside chat will be accessible via the Investors & Media section.
Gain Therapeutics, Inc.

NASDAQ:GANX

View GANX Stock Overview

GANX Rankings

GANX Latest News

GANX Latest SEC Filings

GANX Stock Data

75.00M
37.15M
Biotechnology
Pharmaceutical Preparations
Link
United States
BETHESDA