Gain Therapeutics, Inc. Stock Price, News & Analysis

Gain Therapeutics (Nasdaq: GANX) announced that CEO Eric Richman will participate in a fireside chat at the B. Riley Securities 2022 Virtual Neuro & Ophthalmology Conference on April 28, 2022, from 2:00 to 2:30 p.m. ET. Investors are invited to join via webcast. Gain Therapeutics specializes in drug discovery using its proprietary computational platform, SEE-Tx®, targeting allosteric regulators for various diseases. The company’s lead program focuses on Parkinson’s disease, supported by funding from notable organizations.

Gain Therapeutics (Nasdaq: GANX) presented promising pre-clinical data for its lead candidate GT-02287 at the 2022 Synuclein Meeting in Belgium. The compound enhances GCase levels, promotes lysosomal health, and depletes alpha-synuclein, indicating potential benefits for Parkinson's Disease patients. Key findings include increased GCase activity and neuron survival in relevant models. CEO Eric Richman emphasized the candidate's disease-modifying potential, while the data supports a therapeutic strategy targeting GCase for neurodegenerative diseases.

Gain Therapeutics (Nasdaq: GANX) announced promising pre-clinical data for its Gaucher Disease program, presented at the 2022 Glycolipid and Sphingolipid Biology GRC. The study highlighted that lead compounds significantly increase the levels and activity of the beta-glucocerebrosidase (GCase) protein, enhancing its co-localization with lysosomes and reducing toxic substrate accumulation in neurons. These orally bioavailable compounds may offer a potential treatment for patients with neuronopathic Gaucher disease, addressing a significant unmet medical need.

Gain Therapeutics, Inc. (Nasdaq: GANX) announced significant progress in its lead program for GBA1 Parkinson’s Disease, highlighted by compelling preclinical data and a strong cash position of $36.88 million as of December 31, 2021. The company plans to initiate a first-in-human clinical trial by the end of 2022, following their collaboration with Zentalis Pharmaceuticals to identify novel oncology molecules. Despite increased operating expenses leading to a net loss of $13.89 million, the increase in revenue to $165,000 indicates growing traction in their development efforts.

Gain Therapeutics (Nasdaq: GANX) presented new pre-clinical data at the International Conference on Alzheimer’s and Parkinson’s Diseases demonstrating the potential of their STAR small molecules in treating neurodegenerative diseases. The data shows that enhancing glucocerebrosidase (GCase) activity improves key pathological features linked to Parkinson’s and Alzheimer’s. Results from both Parkinson’s and Alzheimer’s models indicated reductions in neurotoxicity, inflammation, and toxic proteins, suggesting a promising therapeutic avenue for CNS diseases caused by protein misfolding.

Gain Therapeutics (NASDAQ: GANX) announced its participation in key investor and scientific conferences, emphasizing its commitment to neurodegenerative disease research. CEO Eric Richman will present at the Oppenheimer 32nd Annual Healthcare Conference on March 17, 2022, with a webcast available for investors. Additionally, Gain will showcase scientific data at the AD/PD™ 2022 Conference, running from March 15-20, 2022, and sponsor the Krabbe Translational Research Network Meeting from March 15-18, 2022. The company focuses on innovative treatments using its SEE-Tx™ platform.

Gain Therapeutics (NASDAQ: GANX) has unveiled promising pre-clinical data on its Gaucher Disease program at the 18th Annual WORLDSymposium. The study demonstrated that its STARs compounds significantly increase GCase protein levels, diminish inflammatory cytokines, and enhance lysosomal functions in GD-iPSC-derived dopaminergic neurons. These findings validate the company’s drug discovery platform, SEE-Tx®, and indicate potential for a first-in-class therapy. Gain aims to commence IND-enabling studies in Q4 2022, addressing unmet needs in neuronopathic Gaucher Disease treatment.

Gain Therapeutics (Nasdaq: GANX) held its inaugural R&D day webinar, highlighting its advancements in drug discovery through the SEE-Tx platform. The company focuses on developing treatments for GBA1 Parkinson's and Gaucher diseases, alongside other lysosomal storage disorders and metabolic diseases. Key 2022 priorities include initiating a Phase 1 trial for GBA1 Parkinson's and advancing its Gaucher disease program. Their innovative approach leverages new computational methods to identify allosteric targets and accelerate drug discovery.

Gain Therapeutics (Nasdaq: GANX) announced its upcoming R&D Day on February 4, 2022, focusing on utilizing computational technology for allosteric drug discovery. The event will feature expert presentations discussing advancements in targeting undruggable proteins, including key topics on neurodegenerative diseases and oncology. Gain's proprietary SEE-Tx® Platform aims to transform drug discovery by identifying novel allosteric targets. The event is expected to shed light on Gain's pipeline and recent research data relevant to treatments for conditions like Parkinson's and Gaucher Disease.