Gain Therapeutics, Inc. Stock Price, News & Analysis

Gain Therapeutics, Inc. (Nasdaq: GANX) announced CEO Eric Richman will participate in the H.C. Wainwright BioConnect Conference from January 10-13, 2022. This virtual event will enable investor access via webcast, available for 90 days post-event. Gain Therapeutics focuses on innovative drug discovery, particularly targeting allosteric binding sites related to neurodegenerative diseases and lysosomal storage disorders. Supported by notable foundations and programs, the company aims to provide new treatment options for challenging disorders linked to protein misfolding.

Gain Therapeutics, Inc. (Nasdaq: GANX) granted Chief Operating Officer Matthias Alder an option to purchase 200,000 shares and 200,000 restricted stock units. These incentives, part of the 2021 Inducement Equity Incentive Plan, aim to motivate Alder upon joining the company. The options will vest over four years, with a $5.86 exercise price per share, matching the closing stock price on December 22, 2021. The restricted units' vesting is contingent on business and clinical milestones. Gain focuses on innovative treatments for neurodegenerative diseases.

Gain Therapeutics (Nasdaq: GANX) provided a scientific update on its Krabbe disease program, highlighting statistically significant increases in the GALC enzyme and a reduction in toxic substrate psychosine. This breakthrough suggests potential treatment options for patients with Krabbe disease, a severe genetic disorder affecting the nervous system. Initial tests on compounds showed promise in reducing psychosine levels. The next phase involves further evaluation of compounds in complex in vitro models.

Gain Therapeutics, Inc. (Nasdaq: GANX) will present a corporate overview at the Imagine AI + Healthcare Investor Summit on December 7, 2021. CEO Eric Richman and Chief Scientific Officer Xavier Barril, Ph.D., will discuss Gain's innovative approach to targeting allosteric binding sites for neurodegenerative diseases and lysosomal storage disorders. The summit is an opportunity for investors to engage with various companies and learn about advancements in AI within healthcare.

Gain Therapeutics (NASDAQ: GANX) reported its Q3 2021 financial results and announced key corporate developments. The company has $40.98 million in cash, providing a strong financial runway into the second half of 2023. Significant progress was made in patient-derived iPSC studies, showing STAR compounds positively affecting Gaucher and Parkinson's disease markers. Matthias Alder was appointed COO, and a five-member Scientific Advisory Board was established to advance the company’s clinical programs. Q3 revenues increased to $27 thousand, while net loss rose to $4.66 million, reflecting higher R&D and administrative expenses.

Gain Therapeutics (Nasdaq: GANX) presented promising preclinical data on GT-02287, a compound targeting glucocerebrosidase (GCase) for Parkinson’s Disease, at the Society for Neuroscience Annual Meeting. The findings revealed that GT-02287 significantly reduced alpha-synuclein pathology and neuroinflammation while improving behavioral deficits in an animal model. With a favorable toxicity profile, this orally bioavailable compound shows potential in addressing unmet needs for patients suffering from Parkinson’s, particularly those with GBA1 mutations.

Gain Therapeutics (Nasdaq: GANX) announced breakthrough results from a study on its STAR compounds, GT-02287 and GT-02329, for treating Gaucher and GBA1 Parkinson's Disease. Conducted at the University of Maryland, the study demonstrated significant increases in GCase protein levels in iPSC-derived dopaminergic neurons and reductions in phosphorylated α-synuclein. These findings reveal a potential new approach for neurodegenerative disorders, showing a 129% increase in GCase enzyme levels. The company plans to initiate IND-enabling studies soon, promising hope for patients with alpha synucleinopathies.

Gain Therapeutics (Nasdaq: GANX) announced participation at the 12th Annual Jefferies London Healthcare Conference on November 16-19, 2021. CEO Eric Richman will present on November 17 from 9:20 to 9:55 a.m. GMT. Investors can engage in one-on-one meetings either in-person or virtually. The presentation will focus on Gain's innovative drug development strategies targeting neurodegenerative diseases and lysosomal storage disorders through its proprietary SEE-Tx™ platform. For more details, visit Gain’s official website.

Gain Therapeutics, Inc. (Nasdaq: GANX) announced that its management team will present at key medical conferences, including The Michael J. Fox Foundation’s Parkinson’s Disease Therapeutics Webinars on November 10, 2021, and The Society of Neuroscience Annual Meeting on November 9, 2021. The webinars aim to showcase advancements in Parkinson’s research, featuring topics like drug discovery and brain-penetrant allosteric regulators. These sessions will provide insights into ongoing research supported by the foundation. For registration and further information, visit the respective conference websites.