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Structure Therapeutics Inc. develops oral small-molecule therapeutics for chronic metabolic diseases, with a focus on obesity. The clinical-stage global biopharmaceutical company uses a structure-based drug discovery platform and GPCR-targeted pipeline to advance wholly owned compounds, including aleniglipron, an oral nonpeptide GLP-1 receptor agonist, and ACCG-2671, an oral amylin receptor agonist.
Recurring company updates include clinical data from the ACCESS aleniglipron program, obesity and weight-management research presentations, financial results, research-and-development funding, ADS and warrant financings, and leadership or governance changes. The company’s American depositary shares trade under GPCR, with each ADS representing three ordinary shares.
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Structure Therapeutics Inc. (NASDAQ: GPCR) reported its financial results for Q4 2022 and the full year ended December 31, 2022. The company completed its upsized IPO, raising approximately $185.3 million, with net proceeds of around $166.7 million. This funding bolsters its efforts to develop GSBR-1290, an oral GLP-1 agonist for type 2 diabetes and obesity. The Phase 1b study is now completed, and the firm anticipates topline data from the upcoming Phase 1b and Phase 2a studies in the second half of 2023. The net loss for 2022 was $51.3 million, a significant increase from $38.0 million in 2021, primarily due to heightened R&D expenses.
Structure Therapeutics Inc. (NASDAQ: GPCR) has successfully closed its upsized initial public offering (IPO) of 12,351,000 American depositary shares (ADSs) at a price of $15.00 per ADS, generating approximately $185.3 million before expenses. This offering included the full exercise of underwriters' options to purchase an additional 1,611,000 ADSs. The shares commenced trading on Nasdaq on February 3, 2023. Jefferies, SVB Securities, Guggenheim Securities, and BMO Capital Markets served as joint book-running managers for the offering. Structure Therapeutics focuses on developing novel oral small molecule therapeutics for metabolic and pulmonary diseases targeting the GPCR family.