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HALOZYME REPORTS RECORD SECOND QUARTER 2026 RESULTS, BEATS ESTIMATES AND RAISES FULL YEAR 2026 FINANCIAL GUIDANCE

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Halozyme (Nasdaq: HALO) reported record second quarter 2026 results, with total revenue of $481.0 million, up 48% year-over-year, and royalty revenue of $307.7 million, up 50%. Adjusted EBITDA rose to $328.8 million from $225.5 million and GAAP diluted EPS increased to $1.90 from $1.33.

For full-year 2026, Halozyme raised guidance to total revenue of $1.835–$1.910 billion, royalty revenue of $1.220–$1.245 billion, adjusted EBITDA of $1.225–$1.280 billion, and Non-GAAP diluted EPS of $8.65–$9.00. The company signed five new ENHANZE and Hypercon agreements year-to-date and repurchased 4.8 million shares for $332.8 million in Q2 under its buyback programs.

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Positive

  • Total revenue up 48% YoY to $481.0 million in Q2 2026
  • Royalty revenue up 50% YoY to $307.7 million in Q2 2026
  • GAAP diluted EPS increased to $1.90 from $1.33 YoY
  • Adjusted EBITDA up to $328.8 million from $225.5 million YoY
  • Raised 2026 total revenue guidance to $1.835–$1.910 billion from $1.710–$1.810 billion
  • Repurchased 4.8 million shares for $332.8 million at $69.30 average price in Q2 2026
  • Five new ENHANZE/Hypercon deals signed YTD 2026, exceeding full-year collaboration goal
  • Cash and securities increased to $231.9 million from $145.4 million since year-end 2025

Negative

  • Cost of sales rose to $79.2 million from $46.4 million YoY
  • R&D expense increased to $27.7 million from $17.5 million YoY
  • SG&A expense increased to $57.0 million from $41.6 million YoY, including higher litigation and acquisition-related costs
  • Amortization of intangibles rose to $29.5 million from $17.8 million YoY, largely from acquisitions

News Explained

The buyback is authorized up to $1.0 billion, but the company has repurchased $332.8 million and expects at least $400 million in 2026.

The added holder-relevant disclosure is that Halozyme's May 2026 program authorizes repurchases of up to $1.0 billion of outstanding common stock through December 31, 2028, while $332.8 million was repurchased in the second quarter.

That ceiling is not a completed or fully committed purchase amount: the release says the company expects to buy at least $400 million in 2026, rather than committing the full $1.0 billion.

The five collaborations are signed, but their disclosed consideration varies: Vertex's agreement includes a $15 million upfront payment, while Incyte's includes an upfront payment plus potential milestones and royalties and an option for up to two additional targets.

For interpreting the raised 2026 non-GAAP diluted EPS guidance, the release says it does not consider the impact of potential future share repurchases.

Market Reaction – HALO

+5.76% $90.70 1.6x vol
15m delay
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$90.70 Last Price
$82.50 $91.96 Day Range
$10.76B Market Cap
1.6x Rel. Volume

Following this news, HALO has gained 5.76%, reflecting a notable positive market reaction. Our momentum scanner has triggered 6 alerts so far, indicating moderate trading interest and price volatility. The stock is currently trading at $90.70. Trading volume is above average at 1.6x the average, suggesting increased trading activity.

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Total Revenue Increased 48% YOY to $481 million
Royalty Revenue Increased 50% YOY to $308 million

Raises 2026 Financial Guidance Ranges:
Total Revenue of $1.835 - $1.910 billion, YOY Growth of 31% - 37%
Royalty Revenue of $1.220 - $1.245 billion, YOY Growth of 41% - 43%
Adjusted EBITDA of $1.225 - $1.280 billion, YOY Growth of 86% - 95%1
Non-GAAP Diluted EPS of $8.65 - $9.00, YOY Growth of 108% - 117%1

Signed Five New ENHANZE® and Hypercon Collaboration Agreements YTD 2026, Exceeding Goal of Three for Full Year 2026

SAN DIEGO, Aug. 6, 2026 /PRNewswire/ -- Halozyme Therapeutics, Inc. (Nasdaq: HALO) ("Halozyme" or the "Company") today reported its financial and operating results for the second quarter ended June 30, 2026, and provided an update on its recent corporate activities.

"We delivered another quarter of strong performance, with multiple proof points demonstrating the attractive features of ENHANZE as a compounding platform engine: repeatability of success, scalability, diversification and durability of revenues," said Dr. Helen Torley, President and Chief Executive Officer. "Total revenue increased 48% year-over-year to $481 million, royalty revenue increased 50% to $308 million and adjusted EBITDA grew 46% to $329 million, reflecting the strength of our differentiated royalty business. Based on these record results, we are raising our full year 2026 financial guidance."

"Importantly, we are delivering on both our near-term and long-term growth objectives. The ENHANZE value proposition is attracting new partners and additional products from our current partners. We expanded our royalty revenue opportunity by signing five new ENHANZE and Hypercon collaborations through July, including agreements with Vertex, Oruka, GSK, Incyte and an undisclosed partner who is the first to license ENHANZE for a nucleic acid therapeutic. We have also demonstrated our commitment to returning significant capital to shareholders, repurchasing $333 million of shares in 2Q 2026, at an average price of $69.30. Overall, these results illustrate our continued ability to create multiple waves of revenue opportunities that will drive long-term shareholder value," concluded Dr. Torley.

Second Quarter Corporate Highlight:

  • In May 2026, the Company announced a new share repurchase program to repurchase up to $1.0 billion of its outstanding common stock by December 31, 2028, with an expectation of buying back at least $400 million of shares in 2026. During the second quarter of 2026, the Company repurchased 4.8 million shares for $332.8 million at an average price of $69.30 per share under the May 2026 and February 2024 share repurchase programs. The February 2024 share repurchase program was completed in June 2026.

Recent Partner Highlights:

  • In July 2026, Halozyme and Incyte entered into a global collaboration and license agreement to evaluate additional subcutaneous formulations of INCA033989, a first-in-class mutant calreticulin ("mutCALR")-targeted monoclonal antibody, in patients with mutCALR-expressing myeloproliferative neoplasms ("MPNs"), utilizing Halozyme's proprietary ENHANZE® drug delivery technology. Under the collaboration, Incyte also has the option to nominate up to two additional targets for use with ENHANZE®. Under the terms of the agreement, Incyte agreed to make an upfront payment and potential future milestone payments and royalties on net sales of products developed with ENHANZE®.
  • In the third quarter of 2026, the ongoing ARGX-119 adimanebart program was expanded to include a Phase 1 SC bioavailability study with ENHANZE®.

Second Quarter Partner Highlights:

  • In May 2026, Halozyme and an undisclosed company entered into a global collaboration and license agreement that provides the company access to ENHANZE® to develop a nucleic acid therapeutic.
  • In May 2026, Janssen announced pivotal results from the Phase 1b/2 OrigAMI-4 study showing that subcutaneous amivantamab and hyaluronidase-lpuj delivered durable responses in patients with advanced head and neck squamous cell carcinoma previously treated with immunotherapy and chemotherapy and submitted a supplemental Biologics License Application ("sBLA") to the U.S. Food and Drug Administration ("FDA").
  • In May 2026, Viatris initiated a Phase 1 study to evaluate the pharmacokinetics, pharmacodynamics, and tolerability of a single dose of selatogrel in Chinese adults with chronic coronary syndrome.
  • In May 2026, argenx announced FDA approval of a sBLA for VYVGART® Hytrulo with ENHANZE® for the treatment of adult patients with generalized myasthenia gravis including all serotypes – anti-AChR-Ab positive, anti-MuSK-Ab positive, anti-LRP4-Ab positive, and triple seronegative.
  • In May 2026, Halozyme and GSK plc ("GSK") entered into a global collaboration and license agreement for ENHANZE® with multiple oncology targets, including the first potential application in antibody-drug conjugates. Under the terms of the agreement, GSK made an upfront payment and agreed to make potential future milestone payments and royalties on net sales of products developed with ENHANZE®.
  • In May 2026, Halozyme and Oruka Therapeutics, Inc. ("Oruka") entered into a global exclusive collaboration and license agreement for Halozyme's Hypercon™ technology for use with ORKA-001, in development for psoriasis and related inflammatory diseases and one additional target. Under the terms of the agreement, Oruka made an upfront payment and agreed to make potential future milestone payments and mid-single digit royalties on net sales of products developed using the Hypercon™ technology.
  • In May 2026, Takeda announced positive topline results from its pivotal Phase 2/3 trial of TAK-881 with ENHANZE® in Primary Immunodeficiency Disease.
  • In April 2026, Halozyme and Vertex Pharmaceuticals Incorporated ("Vertex") entered into a global exclusive collaboration and license agreement that provides Vertex access to Halozyme's Hypercon™ technology for use in up to three targets. Under the terms of the agreement, Vertex made a $15 million upfront payment and agreed to make potential future milestone payments and royalties on net sales of products developed using the Hypercon™ technology.

Second Quarter 2026 Financial Highlights:

  • Total revenue was $481.0 million, compared to $325.7 million in the second quarter of 2025. The 48% year-over-year increase was primarily driven by royalty revenue growth and an increase in product sales. Revenue included $307.7 million in royalties, an increase of 50% compared to $205.6 million in the second quarter of 2025, primarily driven by continued sales uptake of ENHANZE® partner products that have launched since 2020, predominantly by VYVGART® Hytrulo by argenx and DARZALEX® SC Janssen in all geographies and contributions from other recently launched products.
  • Cost of sales was $79.2 million, compared to $46.4 million in the second quarter of 2025. The increase in cost of sales was primarily due to an increase in bulk rHuPH20 sales.
  • Amortization of intangibles expense was $29.5 million, compared to $17.8 million in the second quarter of 2025. The increase in amortization of intangibles expense was due to the acquisition of Elektrofi, Inc. ("Elektrofi") in November 2025.
  • Research and development expense was $27.7 million, compared to $17.5 million in the second quarter of 2025. The increase was primarily due to the acquisition of Elektrofi and Surf Bio, Inc. ("Surf Bio") in the fourth quarter of 2025.
  • Selling, general and administrative expense was $57.0 million, compared to $41.6 million in the second quarter of 2025. The increase was primarily due to an increase in consulting and professional service fees, including litigation costs incurred in connection with patent infringement litigation, the acquisition of Elektrofi and Surf Bio, and an increase in compensation expense.
  • Operating income was $287.7 million, compared to $202.4 million in the second quarter of 2025.
  • Net income was $229.9 million, compared to $165.2 million in the second quarter of 2025.
  • EBITDA was $321.9 million, compared to $222.9 million in the second quarter of 2025. Adjusted EBITDA was $328.8 million, compared to $225.5 million in the second quarter of 2025.1
  • GAAP diluted earnings per share was $1.90, compared to $1.33 in the second quarter of 2025. Non-GAAP diluted earnings per share was $2.28, compared to $1.54 in the second quarter of 2025.1
  • Cash, cash equivalents, restricted cash and marketable securities were $231.9 million on June 30, 2026, compared to $145.4 million on December 31, 2025. The increase was primarily driven by cash generated from operations.

Financial Outlook for 2026

The Company is raising its 2026 financial guidance ranges, which were last provided on May 11, 2026.

For the full year 2026, the Company expects:

  • Total revenue of $1.835 billion to $1.910 billion, representing growth of 31% to 37% over 2025 total revenue, primarily driven by increases in royalty revenue and product sales from API.
  • Revenue from royalties of $1.220 billion to $1.245 billion, representing growth of 41% to 43% over 2025.
  • Adjusted EBITDA of $1.225 billion to $1.280 billion, representing growth of 86% to 95% over 2025, including new Hypercon™ and Surf Bio investments of approximately $60 million.
  • Non-GAAP diluted earnings per share of $8.65 to $9.00, representing growth of 108% to 117% over 2025. The Company's earnings per share guidance includes new Hypercon™ and Surf Bio investments of approximately $60 million and does not consider the impact of potential future share repurchases.

Table 1. 2026 Financial Guidance



Previous Guidance Range

New Guidance Range


Total Revenue


$1.710 to $1.810 billion

$1.835 to $1.910 billion


Royalty Revenue


$1.130 to $1.170 billion

$1.220 to $1.245 billion


Adjusted EBITDA1


$1.125 to $1.205 billion

$1.225 to $1.280 billion


Non-GAAP Diluted EPS1


$7.75 to $8.25

$8.65 to $9.00


1 EBITDA, Adjusted EBITDA and Non-GAAP Diluted EPS are Non-GAAP financial measures. See "Note Regarding Use of Non-GAAP Financial Measures" below for an explanation of these measures. Reconciliations between GAAP reported and Non-GAAP financial information for actual results are provided at the end of this earnings release.

Webcast and Conference Call

Halozyme will host its Quarterly Update Conference Call for the second quarter ended June 30, 2026 today, Thursday, August 6, 2026, at 1:30 p.m. PT/4:30 p.m. ET. The conference call may be accessed live with pre-registration via link: https://events.q4inc.com/analyst/838122249?pwd=X5tkHKi. The call will also be webcast live through the "Investors" section of Halozyme's corporate website and a recording will be made available following the close of the call. To access the webcast and additional documents related to the call, please visit Halozyme.com.

About Halozyme

Halozyme is a biopharmaceutical company advancing disruptive solutions to improve patient experiences and outcomes for emerging and established therapies. As the innovators of ENHANZE® drug delivery technology with the proprietary enzyme rHuPH20, Halozyme's commercially-validated solution facilitates the subcutaneous delivery of injected drugs and fluids, reducing treatment burden and improving convenience. ENHANZE® has touched more than one million patient lives through ten commercialized products across over 100 global markets and is licensed to leading pharmaceutical and biotechnology companies including Roche, Takeda, Pfizer, Janssen, AbbVie, Eli Lilly, Bristol-Myers Squibb, argenx, ViiV Healthcare, Chugai Pharmaceutical, Acumen Pharmaceuticals, Merus N.V., Skye Bioscience, GSK and Incyte.

Halozyme expanded its drug delivery technology portfolio to develop partner products using Hypercon™ and Surf Bio's hyperconcentration technology. Hypercon™ is an innovative microparticle technology expected to set a new standard in hyperconcentration of drugs and biologics by reducing injection volume for the same dosage and enabling administration in at-home and healthcare-provider settings. The addition of Surf Bio's polymer-based hyperconcentration technology further broadens the range of biologics that can be delivered subcutaneously, meaningfully expanding the scope of opportunities across therapeutic modalities. Together, Hypercon™ and Surf Bio's technology complement ENHANZE® by enabling creation and delivery of highly concentrated biologics. The Hypercon™ technology has been licensed to leading biopharmaceutical partners, including Janssen, Eli Lilly, argenx, Vertex Pharmaceuticals, and Oruka Therapeutics.

Halozyme also develops, manufactures and commercializes drug-device combination products using advanced auto-injector technologies designed to improve convenience, reliability and tolerability, enhancing patient comfort and adherence. The Company has two proprietary commercial products, Hylenex® and XYOSTED®, partnered commercial products and ongoing development programs with Teva Pharmaceuticals and McDermott Laboratories Limited, an affiliate of Viatris Inc.

Halozyme is headquartered in San Diego, CA, with offices in Ewing, NJ; Minnetonka, MN; and Boston, MA. Minnetonka is also the site of its operations facility.

For more information, visit www.halozyme.com and connect with us on LinkedIn.

Note Regarding Use of Non-GAAP Financial Measures

In addition to disclosing financial measures prepared in accordance with U.S. generally accepted accounting principles ("GAAP"), this press release and the accompanying tables contain certain Non-GAAP financial measures. The Company reports earnings before interest, taxes, depreciation, and amortization ("EBITDA"), adjusted EBITDA, Non-GAAP diluted earnings per share, Non-GAAP diluted shares, and guidance with respect to those measures, in addition to, and not as a substitute for, or superior to, financial measures calculated in accordance with GAAP. The Company calculates Non-GAAP diluted earnings per share excluding share-based compensation expense, amortization of debt discounts, intangible asset amortization, one-time items, if any, such as changes in contingent liabilities, inventory adjustments, impairment charges, transaction costs for business combinations and share-based compensation acceleration expenses, intellectual property litigation costs, inducement expenses related to convertible notes, and certain adjustments to income tax expense. The Company calculates Non-GAAP diluted shares excluding the dilutive impact of convertible notes which is used in calculating Non-GAAP diluted earnings per share. The Company calculates EBITDA excluding interest, taxes, depreciation and amortization. The Company calculates adjusted EBITDA excluding one-time items, if any, such as changes in contingent liabilities, inventory adjustments, impairment charges, transaction costs for business combinations and share-based compensation acceleration expenses and intellectual property litigation costs. Reconciliations between GAAP and Non-GAAP financial measures are included at the end of this press release. The Company does not provide reconciliations for forward-looking adjusted measures to GAAP due to the inherent difficulty in forecasting and quantifying certain amounts that are necessary for such reconciliation, including adjustments that could be made for changes in share-based compensation expense and the effects of any discrete income tax items. For the same reasons, the Company is unable to address the probable significance of the unavailable information. The Company provides Non-GAAP financial measures that it believes will be achieved; however, it cannot accurately predict all of the components of the adjusted calculations and the GAAP measures may be materially different than the Non-GAAP measures.

The Company evaluates other items of income and expense on an individual basis for potential inclusion in the calculation of Non-GAAP financial measures and considers both the quantitative and qualitative aspects of the item, including (i) its size and nature, (ii) whether or not it relates to the Company's ongoing business operations and (iii) whether or not the Company expects it to occur as part of the Company's normal business on a regular basis. Non-GAAP financial measures do not have any standardized meaning and are therefore unlikely to be comparable to similarly titled measures presented by other companies. These Non-GAAP financial measures are not meant to be considered in isolation and should be read in conjunction with the Company's consolidated financial statements prepared in accordance with GAAP, and are not prepared under any comprehensive set of accounting rules or principles. In addition, from time to time in the future there may be other items that the Company may exclude for purposes of its Non-GAAP financial measures, and the Company may in the future cease to exclude items that it has historically excluded for purposes of its Non-GAAP financial measures.

The Company considers these Non-GAAP financial measures to be important because they provide useful measures of the operating performance of the Company, exclusive of factors that do not directly affect what the Company considers to be its core operating performance, as well as unusual events. The Non-GAAP measures also allow investors and analysts to make additional comparisons of the operating activities of the Company's core business over time and with respect to other companies, as well as assessing trends and future expectations. The Company uses Non-GAAP financial information in assessing what it believes is a meaningful and comparable set of financial performance measures to evaluate operating trends, as well as in establishing portions of our performance-based incentive compensation programs.

Safe Harbor Statement

In addition to historical information, the statements set forth in this press release include forward-looking statements including, without limitation, statements concerning the Company's financial performance (including the Company's expected financial outlook for 2026) and expectations for future growth, profitability, revenue durability, total revenue, royalty revenue, royalty revenue duration, EBITDA, Adjusted EBITDA, and non-GAAP diluted earnings-per-share, and shareholder value and potential future share repurchases. These forward-looking statements also include statements regarding the Company's potential receipt of upfront payments and payments associated with achievement of certain development, regulatory and sales-based milestones, and royalties on sales of commercialized products from recent collaboration agreements. Forward-looking statements regarding the Company's ENHANZE® drug delivery technology may include the possible benefits and attributes of ENHANZE®, its potential application to aid in the dispersion and absorption of other injected therapeutic drugs and facilitating more rapid delivery and administration of higher volumes of injectable medications through subcutaneous delivery including its potential application with antibody drug conjugates. Forward-looking statements regarding the Company's Hypercon™ and Surf Bio technologies include the possible benefits and attributes of these technologies, including the potential to reduce injection volume for the same dosage of drugs and biologics and possibly enabling administration in at‑home and healthcare‑provider settings and statements concerning certain other potential benefits of these technologies including facilitating administration of injectable medications through subcutaneous delivery by enabling creation and delivery of highly concentrated biologics and potentially lowering the treatment burden, easing treatment access and improving the treatment experience for patients. Forward-looking statements regarding the Company's business may include potential growth and receipt of royalty and milestone payments driven by our partners' development and commercialization efforts, potential new clinical trial study starts and advancement of partnered development programs, regulatory submissions and product launches, the size and growth prospects of our partners' drug franchises, potential new or expanded collaborations and collaborative targets, and potential approvals of new partnered or proprietary products, and the potential timing of these events. These forward-looking statements are typically, but not always, identified through use of the words "expect," "believe," "enable," "may," "will," "could," "intends," "estimate," "anticipate," "plan," "predict," "probable," "potential," "preliminary," "possible," "should," "continue," and other words of similar meaning and involve risk and uncertainties that could cause actual results to differ materially from those in the forward-looking statements. Actual results could differ materially from the expectations contained in these forward-looking statements as a result of several factors, including uncertainties concerning future matters such as unexpected results or delays in the Company's repurchases of the Company's shares under the share repurchase program, market conditions, changes in domestic and foreign business, changes in the competitive environment in which the Company operates, unexpected early expiration or termination of the patent terms for the Company's drug delivery technologies, unexpected levels of revenues, expenditures and costs, unexpected results or delays in the growth of the Company's business, or in the development, regulatory review or commercialization of the Company's partnered or proprietary products, regulatory approval requirements, unexpected adverse events or patient outcomes and competitive conditions. These and other factors that may result in differences are discussed in greater detail in the Company's most recent Annual Report on Form 10-K and Quarterly Report on Form 10-Q filed with the Securities and Exchange Commission, including under the headings "Risk Factors" and "Management's Discussion and Analysis of Financial Condition and Results of Operations". Except as required by law, the Company undertakes no duty to update forward-looking statements to reflect events after the date of this release.

Contacts: 
Tram Bui
VP, Investor Relations and Corporate Communications
609-333-7668
tbui@halozyme.com

Sydney Charlton
Teneo
917-972-8407
sydney.charlton@teneo.com

 

Halozyme Therapeutics, Inc.

Condensed Consolidated Statements of Operations

(Unaudited)

(In thousands, except per share amounts)




Three Months Ended


Six Months Ended



June 30,


June 30,



2026


2025


2026


2025

Revenues









Royalties


$   307,699


$   205,639


$   548,380


$   373,831

Product sales, net


129,626


81,510


260,050


159,551

Revenues under collaborative agreements


43,674


38,570


49,277


57,198

Total revenues


480,999


325,719


857,707


590,580

Operating expenses









Cost of sales


79,171


46,359


158,409


94,762

Amortization of intangibles


29,512


17,762


59,024


35,524

Research and development


27,664


17,543


53,224


32,342

Selling, general and administrative


56,998


41,614


114,879


83,976

Total operating expenses


193,345


123,278


385,536


246,604

Operating income


287,654


202,441


472,171


343,976

Other income (expense)









Investment and other income, net


2,836


6,891


4,154


13,709

Interest expense


(5,588)


(4,394)


(11,096)


(8,919)

Income before income tax expense


284,902


204,938


465,229


348,766

Income tax expense


54,989


39,778


85,267


65,511

Net income


$   229,913


$   165,160


$   379,962


$   283,255










Earnings per share









Basic


$       1.96


$       1.36


$       3.23


$       2.32

Diluted


$       1.90


$       1.33


$       3.11


$       2.26










Weighted average common shares outstanding









Basic


117,274


121,343


117,707


122,274

Diluted


121,215


124,158


122,092


125,452

 

Halozyme Therapeutics, Inc.

Condensed Consolidated Balance Sheets

(Unaudited)

(In thousands)





June 30,
2026


December 31,
2025

ASSETS





Current assets





Cash and cash equivalents


$      163,138


$      133,820

Marketable securities, available-for-sale


67,865


9,000

Accounts receivable, net and contract assets


455,827


441,273

Inventories


137,135


176,475

Prepaid expenses and other current assets


109,059


64,639

Total current assets


933,024


825,207

Property and equipment, net


84,271


82,137

Prepaid expenses and other assets


55,090


53,551

Goodwill


581,732


580,360

Intangible assets, net


922,443


981,467

Restricted cash


848


2,601

Total assets


$    2,577,408


$    2,525,323






               LIABILITIES AND STOCKHOLDERS' EQUITY





Current liabilities





Accounts payable


$        23,608


$        20,899

Accrued expenses


111,861


156,193

Current portion of long-term debt, net


208,970


Total current liabilities


344,439


177,092

Long-term debt, net


1,937,684


2,142,630

Other long-term liabilities


102,681


113,863

Deferred tax liabilities, net


49,061


42,924

Total liabilities


2,433,865


2,476,509






Stockholders' equity





Common stock


114


118

Additional paid-in capital



12,002

Accumulated other comprehensive loss


(7,830)


(18,092)

Retained earnings


151,259


54,786

Total stockholders' equity


143,543


48,814

Total liabilities and stockholders' equity


$    2,577,408


$    2,525,323

 

Halozyme Therapeutics, Inc.

GAAP to Non-GAAP Reconciliations

EBITDA

(Unaudited)

(In thousands)




Three Months Ended



June 30,



2026


2025

GAAP Net Income


$   229,913


$   165,160

Adjustments





Investment and other income, net


(2,581)


(6,891)

Interest expense


5,588


4,394

Income tax expense


54,989


39,778

Depreciation and amortization


33,967


20,502

EBITDA


321,876


222,943

Adjustments





Intellectual property litigation costs(1)


6,936


2,561

Adjusted EBITDA


$   328,812


$   225,504

(1)

Adjustment relates to litigation costs incurred by Halozyme in connection with Halozyme's patent infringement litigation against Merck Sharp & Dohme LLC ("Merck"). These charges are excluded because the Company does not believe they are reflective of the Company's ongoing business and operating results.

 

Halozyme Therapeutics, Inc.

GAAP to Non-GAAP Reconciliations

Net Income and Diluted EPS

(Unaudited)

(In thousands, except per share amounts)




Three Months Ended



June 30,



2026


2025

GAAP Net Income


$   229,913


$   165,160

Adjustments





Share-based compensation


17,698


12,161

Amortization of debt discount


2,253


1,852

Amortization of intangible assets


29,512


17,762

Intellectual property litigation costs(1)


6,936


2,561

Income tax effect of above adjustments(2)


(13,677)


(8,158)

Non-GAAP Net Income


$   272,635


$   191,338






GAAP Diluted EPS


$       1.90


$       1.33

Adjustments





Share-based compensation


0.15


0.10

Amortization of debt discount


0.02


0.01

Amortization of intangible assets


0.25


0.14

Intellectual property litigation costs(1)


0.06


0.02

Income tax effect of above adjustments(2)


(0.11)


(0.07)

Non-GAAP Diluted EPS


$       2.28


$       1.54






GAAP Diluted Shares


121,215


124,158

Adjustments





Adjustment for dilutive impact of 2028 Convertible Senior Notes(3)


(1,497)


(199)

Non-GAAP Diluted Shares


119,718


123,959

Dollar amounts, as presented, are rounded. Consequently, totals may not add up.


(1)

Adjustment relates to litigation costs incurred by Halozyme in connection with Halozyme's patent infringement litigation against Merck. These charges are excluded because the Company does not believe they are reflective of the Company's ongoing business and operating results.

(2)

Adjustments relate to taxes for the reconciling items, as well as excess benefits or tax deficiencies from share-based compensation, and the quarterly impact of other discrete items. 

(3)

Adjustment made for the dilutive effect of our Convertible Senior Notes due 2028 when the effect is not the same on a GAAP and Non-GAAP basis for the reporting period.



Halozyme Therapeutics, Inc. Logo. (PRNewsFoto/Halozyme Therapeutics, Inc.)

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SOURCE Halozyme Therapeutics, Inc.

FAQ

How did Halozyme (HALO) perform financially in Q2 2026?

Halozyme reported strong Q2 2026 growth, with total revenue of $481.0 million, up 48% year-over-year. According to Halozyme, royalty revenue reached $307.7 million (up 50%), adjusted EBITDA was $328.8 million, and GAAP diluted EPS increased to $1.90 from $1.33.

What full-year 2026 guidance did Halozyme (HALO) raise on August 6, 2026?

Halozyme raised 2026 guidance to total revenue of $1.835–$1.910 billion and royalty revenue of $1.220–$1.245 billion. According to Halozyme, adjusted EBITDA is now forecast at $1.225–$1.280 billion and Non-GAAP diluted EPS at $8.65–$9.00, all above prior ranges.

How much stock did Halozyme (HALO) repurchase in Q2 2026 and under what program?

Halozyme repurchased 4.8 million shares for $332.8 million in Q2 2026 at an average price of $69.30. According to Halozyme, these buybacks were executed under its May 2026 and February 2024 repurchase programs; the February 2024 program was completed in June 2026.

What new ENHANZE and Hypercon collaboration agreements did Halozyme (HALO) sign in 2026?

Halozyme signed five new collaborations year-to-date 2026, exceeding its full-year goal of three. According to Halozyme, partners include Vertex, Oruka, GSK, Incyte and an undisclosed company, expanding ENHANZE and Hypercon use into oncology, inflammatory disease and nucleic acid therapeutics.

How fast are Halozyme’s (HALO) royalties growing and what drives them?

Halozyme’s Q2 2026 royalty revenue grew 50% year-over-year to $307.7 million. According to Halozyme, growth is primarily driven by ENHANZE-based products launched since 2020, notably VYVGART Hytrulo by argenx and DARZALEX SC by Janssen, plus contributions from other recent launches.

What does Halozyme’s 2026 EPS guidance mean for HALO shareholders?

Halozyme expects 2026 Non-GAAP diluted EPS of $8.65–$9.00, implying 108–117% year-over-year growth. According to Halozyme, this outlook incorporates about $60 million of new Hypercon and Surf Bio investments and excludes any impact from potential future share repurchases on earnings per share.

How did Halozyme’s acquisitions affect Q2 2026 expenses and results?

Halozyme’s acquisitions of Elektrofi and Surf Bio contributed to higher R&D and amortization expenses in Q2 2026. According to Halozyme, R&D rose to $27.7 million and amortization of intangibles to $29.5 million, while overall operating income still increased to $287.7 million.