Welcome to our dedicated page for Harmony Biosciences Holdings news (Ticker: HRMY), a resource for investors and traders seeking the latest updates and insights on Harmony Biosciences Holdings stock.
Harmony Biosciences Holdings, Inc. develops and commercializes therapies for rare neurological diseases, with WAKIX® (pitolisant) as its commercial product for adult narcolepsy-associated cataplexy. News about HRMY centers on WAKIX revenue trends, market access and payer dynamics, intellectual-property protection, and product guidance.
Company updates also cover clinical and regulatory progress across its CNS pipeline, including pitolisant lifecycle programs and candidates such as EPX-100 for Dravet syndrome and Lennox-Gastaut syndrome. Recurring announcements include quarterly results, investor-conference presentations, executive and board changes, and pipeline data presentations at medical meetings.
Harmony Biosciences (NASDAQ: HRMY) will present encore open-label extension data from the Phase 3 ARGUS trial of EPX-100 (clemizole hydrochloride) for Dravet syndrome at the 2026 AAN Annual Meeting, April 18–22 in Chicago. Poster P10.010 is scheduled for April 22, 2026, 8:00–9:00 AM CT.
The ARGUS trial is currently enrolling; further trial information is available at argustrial.com.
Harmony Biosciences (Nasdaq: HRMY) appointed Glenn Reicin as Chief Financial Officer effective April 14, 2026 and reiterated 2026 net product revenue guidance of $1.0 to $1.04 billion in Wakix sales.
Reicin will oversee finance, FP&A, accounting, treasury, investor relations, and risk management and joins from prior CFO roles where he led IPO readiness and fundraising activities.
Harmony Biosciences (NASDAQ: HRMY) named Peter Anastasiou as Chief Operating Officer and updated its board, appointing Troy Ignelzi and nominating Geno J. Germano for election at the 2026 Annual Meeting.
Mr. Anastasiou resigned from the Board to join the executive team; Antonio Gracias will not stand for re-election. The moves aim to support Harmony's next growth phase and long‑term value creation.
Harmony Biosciences (Nasdaq: HRMY) said its management team will take part in a fireside chat at the 25th Annual Needham Virtual Healthcare Conference on April 13, 2026 at 9:30 a.m. ET. A live webcast will be available on Harmony's investor relations website.
Harmony Biosciences (Nasdaq: HRMY) said its management team will attend three investor conferences in Miami, FL on March 9–10, 2026: Leerink Partners Global Healthcare Conference, UBS Biotech Summit, and Barclays 28th Annual Global Healthcare Conference.
Investors can expect management presentations and meetings during those dates.
Harmony Biosciences (NASDAQ: HRMY) reported 2025 net product revenue of $868.5M for WAKIX and Q4 revenue of $243.8M, ~22% year-over-year growth. The company reiterated 2026 WAKIX guidance of $1.0–$1.04B, cited recent ANDA settlements, a Q2 2026 NDA plan for pitolisant GR, and multiple late-stage pipeline programs.
Cash and investments totaled $882.5M at year-end; R&D and operating expenses increased as the company advances lifecycle and label-expansion efforts.
Harmony Biosciences (Nasdaq: HRMY) announced FDA approval of WAKIX (pitolisant) for treatment of cataplexy in pediatric narcolepsy patients aged 6 years and older.
WAKIX is now the first-and-only FDA-approved non-scheduled treatment for pediatric and adult narcolepsy with or without cataplexy. The company is pursuing pediatric exclusivity (potential +6 months) and cites utility patents filed through 2044.
Harmony Biosciences (Nasdaq: HRMY) will report fourth quarter and full year 2025 financial results on February 24, 2026 before U.S. markets open. A conference call and webcast will be held on February 24, 2026 at 8:30 a.m. ET to discuss results.
Investors can join via domestic dial-in 800-274-7083 or international 203-518-9786 with passcode HRMYQ425. A live and replay webcast will be available on the company investor website.
Harmony Biosciences (Nasdaq: HRMY) reported preliminary, unaudited Q4 2025 net product revenue of ~$243 million and full-year 2025 net revenue of ~$868 million, a ~21% increase versus 2024. The company guided WAKIX revenue of $1.0–$1.04 billion for 2026 and noted ~8,500 average patients in Q4 2025 after adding ~400 patients. Harmony highlighted a late-stage CNS pipeline with five ongoing Phase 3 registrational trials, Phase 3 readouts for certain programs in 2026–2027, and a Phase 1 orexin-2 agonist (BP1.15205) with PK data expected mid-2026. The company also said the ZYN002 Fragile X program is being phased out and provided upcoming presentation details for the J.P. Morgan Healthcare Conference on January 13, 2026.
Harmony Biosciences (Nasdaq: HRMY) will present at the 44th Annual J.P. Morgan Healthcare Conference in San Francisco. Jeffrey M. Dayno, M.D., President and CEO, is scheduled to present on Tuesday, January 13, 2026 at 4:30 p.m. PT / 7:30 p.m. ET. A live webcast will be available on Harmony's investor relations website.
Investors can view the presentation via the company's webcast page at https://ir.harmonybiosciences.com/.