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IGC Pharma Announces Publication of Landmark Caregiver Book on Alzheimer's Disease

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IGC Pharma (NYSE:IGC) announced publication of "Caring for a Loved One with Alzheimer's Disease: First Hand Experiences" on December 2, 2025, a caregiver-focused book sponsored by IGC and authored by clinical neuropsychologists including Dr. Juan Carlos Arango-Lasprilla and Dr. Sandra Báez.

The book combines science-based educational chapters (disease progression, diagnosis, treatments, caregiver health, planning) with first-person caregiver stories addressing emotional, behavioral, and social challenges. IGC said the publication aligns with its mission while it advances IGC-AD1 in the Phase 2 CALMA trial for agitation in Alzheimer's dementia and develops AI-driven therapeutic programs.

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Positive

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Negative

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News Market Reaction – IGC

-2.86%
1 alert
-2.86% Session close to close
$28.42M Market Cap
0.4x Rel. Volume

In the Dec 2 session, IGC declined 2.86%, reflecting a moderate negative market reaction.

Data tracked by StockTitan Argus on the day of publication.

Market Context

This announcement emphasizes IGC’s multidimensional approach to Alzheimer’s by pairing its Phase 2 C...
Analysis

This announcement emphasizes IGC’s multidimensional approach to Alzheimer’s by pairing its Phase 2 CALMA trial of IGC-AD1 with educational outreach through a caregiver book. Recent filings also detail ongoing clinical investment and a resale registration for existing shareholders, underscoring both development ambitions and potential secondary supply. Investors monitoring this story may focus on future CALMA data, AI program milestones, cash resources, and how outreach efforts support eventual commercialization.

Key Figures

Trial phase: Phase 2
1 metrics
Trial phase Phase 2 IGC-AD1 CALMA trial for agitation in Alzheimer’s dementia

Historical Context

5 past events · Latest: Dec 10 (Positive)
Pattern 5 events
Date Event Sentiment 24h Move Catalyst
Dec 10 Analyst coverage update Positive +14.8% Analyst raised price target after Q2 results and clinical progress outlook.
Dec 09 Clinical trial progress Positive +2.5% CALMA Phase 2 enrollment reached 65% with trial on track for early 2026.
Dec 02 Corporate mission update Positive -2.9% Publication of Alzheimer’s caregiver book reinforcing mission and pipeline focus.
Nov 25 AI platform update Positive -0.4% MINT-AD AI model progress using 14 large-scale studies for risk stratification.
Nov 17 Earnings and operations Negative -5.0% Q2 results with higher R&D, revenue decline, and a larger net loss.

24h Move is the share-price change in the day after each event; other market factors may also have contributed.

Pattern Detected

Positive clinical and analyst updates have often aligned with upside, while strategic or AI initiatives and this caregiver book have occasionally seen modest selloffs despite constructive narratives.

Recent Company History

Over the past month, IGC reported several developments around Alzheimer’s programs and corporate strategy. On Nov 17, Q2 results showed higher R&D, lower revenue, and a larger net loss. Later in November, the company highlighted advances in its MINT-AD AI platform. On Dec 2, it announced the Alzheimer’s caregiver book aligning with its CALMA Phase 2 trial of IGC-AD1. Subsequent updates included CALMA enrollment milestones and an analyst coverage report with a higher price target, which drew the strongest positive price reaction.

Key Terms

alzheimer's disease, phase 2, cannabinoid-based, amyloid plaques, +3 more
7 terms
alzheimer's disease medical
"Caring for a Loved One with Alzheimer's Disease: First Hand Experiences," a comprehensive"
A progressive brain disorder that slowly erodes memory, thinking and the ability to carry out daily tasks as nerve cells are damaged and lost; symptoms typically worsen over years and can lead to severe impairment. Investors care because it drives a large, growing market for diagnostics, treatments and care services, but also carries high scientific, regulatory and commercial risk—similar to developing a complex new product that must pass difficult safety tests before it can reach patients.
phase 2 medical
"IGC-AD1, currently advancing through the Phase 2 CALMA trial for agitation in Alzheimer's"
Phase 2 is the mid-stage clinical trial where a new drug or treatment is tested in a larger group of patients to see if it works and to keep checking safety after initial human testing. Think of it as a field test that proves whether a product actually delivers its promised benefit. Investors watch Phase 2 closely because its results strongly influence a medicine’s chances of reaching the market, the size of its potential sales, and the company’s valuation.
cannabinoid-based medical
"advancing IGC-AD1, a cannabinoid-based investigational therapy in Phase 2 trials for agitation"
Cannabinoid-based describes products, medicines, or technologies built around cannabinoids — chemical compounds originally found in cannabis plants or their synthetic equivalents — as the primary active ingredient. Investors care because these offerings carry specific market opportunities and risks tied to regulation, clinical proof, intellectual property and public acceptance; think of cannabinoids as the key ingredient in a recipe that can drive sales if safe and legal, or limit them if not.
amyloid plaques medical
"programs targeting amyloid plaques, tau pathology, neuroinflammation, and mitochondrial"
Protein fragments that collect into dense clumps between brain cells, similar to sticky residue building up on machinery and hindering normal signaling. They are most often associated with neurodegenerative disorders and matter to investors because their presence, measurement, and clearance drive clinical trial design, regulatory decisions, potential treatment approvals, and market expectations for companies developing diagnostics or therapies, which can have major effects on stock value and healthcare spending.
tau pathology medical
"programs targeting amyloid plaques, tau pathology, neuroinflammation, and mitochondrial"
Tau pathology is the buildup and abnormal clumping of a protein called tau inside brain cells, which disrupts their normal function and can lead to progressive memory and thinking problems. For investors, tau pathology matters because it is a central target for diagnostics and treatments in neurodegenerative diseases; progress or setbacks in detecting or treating tau-related damage can markedly affect the value of biotech companies and the outlook for related drug candidates.
neuroinflammation medical
"programs targeting amyloid plaques, tau pathology, neuroinflammation, and mitochondrial"
Neuroinflammation is the brain or spinal cord’s immune reaction to injury, infection, or abnormalities, where cells and molecules become active to protect or repair nervous tissue. It matters to investors because it underlies many neurological diseases and is a common target for drugs and diagnostic tools; positive or negative trial results, safety signals, or new therapies can change a company’s value much like a major repair plan or recall would affect a carmaker’s prospects.
mitochondrial dysfunction medical
"tau pathology, neuroinflammation, and mitochondrial dysfunction."
Mitochondrial dysfunction is when the cell’s energy factories, called mitochondria, fail to make enough energy for cells to work properly, which can cause tissue damage and contribute to many diseases. For investors, it matters because therapies, tests, or devices aimed at fixing or detecting this problem can create market opportunities or clinical risk; think of it as a failing car battery that drives demand for repairs, replacements, and related medical products.

AI-generated analysis. How Rhea-AI works. Not financial advice.

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New Caregiver Resource Showcases Expert Contributions and Reinforces IGC Pharma's Leadership in Alzheimer's Innovation

POTOMAC, MD / ACCESS Newswire / December 2, 2025 / IGC Pharma, Inc. (NYSE American:IGC) ("IGC" or the "Company"), a clinical-stage biotechnology company leveraging Artificial Intelligence (AI) to develop innovative treatments for Alzheimer's disease, today announced the publication of "Caring for a Loved One with Alzheimer's Disease: First Hand Experiences," a comprehensive caregiver-focused book sponsored by IGC Pharma and authored by several of the world's leading experts in neuropsychology and dementia care.

The book written by renowned clinical neuropsychologists Dr. Juan Carlos Arango-Lasprilla and Dr. Sandra Báez, alongside co-authors Dr. Valeria Villamizar, and Dr. Natalia Valech presents science-based education, practical strategies, and real-life narratives from families impacted by Alzheimer's disease. Dr. Sandra Báez serves as an external advisor to IGC Pharma, contributing her expertise to the company's long-term strategy to improve the understanding, treatment, and lived experience of Alzheimer's disease worldwide.

"This book represents an essential contribution to the global Alzheimer's community," said Ram Mukunda, CEO of IGC Pharma. "Our diverse pipeline of candidates, including IGC-AD1, currently advancing through the Phase 2 CALMA trial for agitation in Alzheimer's dementia, demonstrates how we are translating scientific innovation into potential treatments, and this book complements those efforts by supporting broader community engagement and awareness as we move toward commercialization."

A Comprehensive Guide Supporting Families and Caregivers
The book is organized into two major sections:

1. Educational Chapters on Alzheimer's Disease
Covering topics such as:

  • What Alzheimer's disease is and how it progresses

  • Causes, risk factors, and protective factors

  • Diagnosis and clinical evaluation

  • Myths and misconceptions

  • The role of the caregiver and the family

  • Caregiver mental and physical health

  • Planning for the future and long-term care

  • Available pharmacological and non-pharmacological treatments

These chapters provide scientifically grounded guidance for caregivers seeking clarity, validation, and practical support.

2. First-Person Caregiver Stories
The second half of the book contains real-life testimonies of families who have cared for loved ones with Alzheimer's disease. These narratives highlight:

  • Emotional challenges and resilience

  • Communication difficulties and behavioral symptoms

  • The importance of social support

  • The value of meaningful connections, even in advanced stages

Each story offers reflection, empathy, and concrete lessons for navigating the caregiving journey.

Strategic Alignment with IGC Pharma's Mission
The publication reinforces IGC Pharma's commitment to addressing Alzheimer's disease from every angle, scientific, social, and therapeutic. The company is currently advancing IGC-AD1, a cannabinoid-based investigational therapy in Phase 2 trials for agitation in Alzheimer's dementia, while simultaneously developing AI-driven tools and additional therapeutic programs targeting amyloid plaques, tau pathology, neuroinflammation, and mitochondrial dysfunction.

By supporting educational resources such as this book, IGC Pharma not only strengthens community awareness but also enhances its long-term strategic position as a leader in Alzheimer's therapeutic innovation and patient-centered solutions.

About the Authors (External Advisors to IGC Pharma)

  • Dr. Juan Carlos Arango-Lasprilla - A globally recognized neuropsychologist, author of 24 books and 450+ scientific articles.

  • Dr. Sandra Báez - Associate Professor at Los Andes University (Colombia) and award-winning researcher in social cognition and neuropsychology and 120+ scientific articles.

  • Natalia Valech - Neuropsychologist specializing in psychogerontology with clinical experience across Spain, Chile, and Canada.

  • Valeria Villamizar - Psychologist focused on cognition, behavior, and applied neuroscience in Alzheimer's care.

The book is now available for free download. To access it, click here for the English edition or here for the Spanish edition. We encourage caregivers, families, clinicians, and community organizations to share these resources widely to support all those affected by Alzheimer's disease.

About IGC Pharma (dba IGC):
IGC Pharma (NYSE American:IGC) is a clinical-stage biotechnology company leveraging AI to develop innovative treatments for Alzheimer's and metabolic disorders. Our lead asset, IGC-AD1, is a cannabinoid-based therapy currently in a Phase 2 trial (CALMA) for agitation in Alzheimer's dementia. Our pipeline includes TGR-63, targeting amyloid plaques, and early-stage programs focused on neurodegeneration, tau proteins, and metabolic dysfunctions. We integrate AI to accelerate drug discovery, optimize clinical trials, and enhance patient targeting. With a complete patent portfolio and a commitment to innovation, IGC Pharma is advancing breakthrough therapies.

Forward-Looking Statements:
This press release contains forward-looking statements. These forward-looking statements are based largely on IGC Pharma's expectations and are subject to several risks and uncertainties, certain of which are beyond IGC Pharma's control. Actual results could differ materially from these forward-looking statements as a result of, among other factors, the Company's failure or inability to commercialize one or more of the Company's products or technologies, including the products or formulations described in this release, or failure to obtain regulatory approval for the products or formulations, where required, or government regulations affecting AI or the AI algorithms not working as intended or producing accurate predictions; general economic conditions that are less favorable than expected; the FDA's general position regarding cannabis- and hemp-based products; and other factors, many of which are discussed in IGC Pharma's U.S. Securities and Exchange Commission ("SEC") filings. IGC incorporates by reference its Annual Report on Form 10-K filed with the SEC on June 27, 2025, as if fully incorporated and restated herein. Considering these risks and uncertainties, there can be no assurance that the forward-looking information contained in this release will occur. IGC Pharma, Inc. assumes no obligation to update forward-looking statements contained in this release as the result of new information or future events or developments.

Contact Information:
Rosalyn Christian / John Nesbett
IMS Investor Relations
igc@imsinvestorrelations.com
(203) 972-9200

SOURCE: IGC Pharma, Inc.



View the original press release on ACCESS Newswire

FAQ

What did IGC announce on December 2, 2025 regarding Alzheimer's caregiver resources?

IGC announced sponsorship and publication of a caregiver book titled "Caring for a Loved One with Alzheimer's Disease: First Hand Experiences" on December 2, 2025.

Who authored the IGC-sponsored Alzheimer's caregiver book and what expertise do they hold?

The book was authored by clinical neuropsychologists including Dr. Juan Carlos Arango-Lasprilla and Dr. Sandra Báez, who serves as an external advisor to IGC.

How does the new book relate to IGC Pharma's clinical program for Alzheimer's (IGC ticker IGC)?

IGC said the publication complements its therapeutic work while it advances IGC-AD1 in the Phase 2 CALMA trial for agitation in Alzheimer's dementia.

What topics are covered in IGC's caregiver book that may aid families and caregivers?

The book covers disease progression, causes and risk factors, diagnosis, treatments, caregiver health, planning for long-term care, and firsthand caregiver stories with practical strategies.

Will IGC's book provide real-life caregiver perspectives for families affected by Alzheimer's?

Yes; the second half contains first-person caregiver stories highlighting emotional challenges, communication difficulties, social support, and caregiving lessons.