Welcome to our dedicated page for Immatics N.V news (Ticker: IMTX), a resource for investors and traders seeking the latest updates and insights on Immatics N.V stock.
Immatics N.V. (NASDAQ: IMTX) is a clinical-stage biopharmaceutical company focused on T cell‑redirecting cancer immunotherapies, with a strong emphasis on precision targeting of PRAME. The IMTX news feed on Stock Titan aggregates company‑issued updates, investor communications and regulatory disclosures so readers can follow how Immatics’ pipeline and corporate strategy evolve over time.
Recent Immatics news has highlighted multiple strands of its PRAME franchise. These include data from the Phase 1b program of anzu‑cel (anzutresgene autoleucel, formerly IMA203) PRAME cell therapy in metastatic melanoma and uveal melanoma, the ongoing randomized Phase 3 SUPRAME trial in previously treated advanced cutaneous melanoma, and new results from the second‑generation PRAME cell therapy IMA203CD8 in advanced solid tumors such as ovarian carcinoma, melanoma and synovial sarcoma.
Investors and observers can also track updates on Immatics’ TCR Bispecific pipeline, including IMA402, a PRAME‑directed bispecific, and IMA401, a MAGEA4/8‑directed bispecific. Company releases describe Phase 1a dose escalation data, favorable tolerability at recommended dose ranges, and deep, durable responses in heavily pretreated patients with a range of solid tumors. Financial results, underwritten equity offerings, leadership appointments and collaboration milestones with partners such as Moderna are also reported in the company’s quarterly and transaction‑related news.
By following IMTX news, readers gain context on clinical trial progress, interim data readouts, financing activities and strategic shifts that shape Immatics’ development path in PRAME‑positive cancers and other solid tumors. Bookmark this page to access a consolidated stream of press releases and related announcements as they are published.
Immatics N.V. (NASDAQ: IMTX), a clinical-stage biopharmaceutical company focused on T cell-redirecting cancer immunotherapies, has announced an upcoming oral presentation at the 21st International Congress of the Society for Melanoma Research. The presentation will feature updated clinical data on the company's lead cell therapy candidate, ACTengine® IMA203, which targets PRAME in PD1-refractory metastatic melanoma.
The presentation is scheduled for October 11, 2024, from 8:00 to 8:20 am CDT, during the Plenary Session 1 on Developmental Immunotherapy. Dr. Martin Wermke from the University Hospital Dresden, Germany, will deliver the presentation titled 'ACTengine IMA203 TCR-T targeting PRAME in PD1-refractory metastatic melanoma – Clinical Update'.
Immatics N.V. (NASDAQ: IMTX) reported its Q2 2024 financial results and provided a business update. Key highlights include:
- ACTengine® IMA203 targeting PRAME showed a 55% confirmed objective response rate in 30 metastatic melanoma patients, with a median duration of response of 13.5 months.
- First Phase 1 data from TCER® IMA401 (MAGEA4/8) to be presented at ESMO Congress 2024.
- Cash position of $568.5 million as of June 30, 2024, funding operations into 2027.
- Q2 2024 revenue was $20.1 million, with a net loss of $19.3 million.
- Appointment of Alise Reicin M.D. to Board of Directors.
Immatics N.V. (NASDAQ: IMTX), a clinical-stage biopharmaceutical company focused on T cell-redirecting cancer immunotherapies, has appointed Alise Reicin, M.D., to its Board of Directors. Dr. Reicin, currently President and CEO of Tectonic Therapeutic, brings extensive experience in clinical development, including her role in the approval of Keytruda®. Her appointment comes as Immatics advances its pipeline of TCR-based cell therapy and bispecific product candidates.
Peter Chambré, Chairman of Immatics' Board, highlighted Dr. Reicin's expertise in facilitating the approval and launch of novel therapies. Dr. Reicin expressed enthusiasm for Immatics' potential, particularly noting the deep and durable responses from its lead cell therapy candidate, ACTengine® IMA203, in advanced metastatic melanoma patients. Her appointment continues through the Company's Annual General Meeting in 2025.
Immatics N.V. (NASDAQ: IMTX) has announced an upcoming oral presentation at the European Society for Medical Oncology (ESMO) Congress 2024. The presentation will showcase the first proof-of-concept clinical data for TCER® IMA401, their next-generation, half-life extended TCR Bispecific molecule targeting MAGEA4/8.
The presentation, titled "Initial safety, pharmacokinetics, and anti-tumor activity data of TCER IMA401, a MAGEA4/8-directed half-life extended TCR Bispecific, in Phase 1 dose escalation," will be delivered by Dr. Martin Wermke from University Hospital Dresden, Germany. It is scheduled for September 16, 2024, at 11:25 CEST in the Granada Auditorium - Hall 6, as part of the Investigational Immunotherapy session.
Full abstracts will be available on the ESMO website on September 9, 2024, at 00:05 CEST.
Immatics (NASDAQ: IMTX) reported its Q1 2024 financial results and provided a business update, including clinical data from their ongoing Phase 1 trial of ACTengine® IMA203 targeting PRAME. The trial showed a 55% confirmed objective response rate in heavily pre-treated metastatic melanoma patients, with tumor shrinkage in 87% and a median response duration of 13.5 months. IMA203 maintained a favorable safety profile. A Phase 2/3 trial is planned for 2024.
The company also completed a $201.5 million public offering in January 2024, ending the quarter with $609.7 million in cash and equivalents, funding operations into 2027. Q1 2024 revenues were $32.8 million, largely due to a terminated collaboration, while net loss narrowed to $3.4 million from $21.3 million in Q1 2023. Upcoming milestones include updates on IMA203, IMA203CD8, and TCER® programs in 2H 2024.
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